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PBE - ETF AI Analysis

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PBE

Invesco Dynamic Biotechnology & Genome ETF (PBE)

Rating:71Outperform
Price Target:
PBE, the Invesco Dynamic Biotechnology & Genome ETF, earns a solid overall rating thanks to several strong, well-positioned biotech leaders like Vertex, Regeneron, Gilead, and United Therapeutics, which show robust financial performance, healthy revenue growth, and positive earnings outlooks. Royalty Pharma also adds strength with strong profitability and strategic acquisitions, while weaker names like Alnylam and Bio-Techne, which face high valuations and leverage or slowing revenue, slightly weigh on the fund. The main risk factor is the ETF’s heavy concentration in the biotechnology and genome sector, which can make it more sensitive to industry-specific news, regulation, and market swings.
Positive Factors
Strong Recent Performance
The ETF has shown strong gains over the past three and twelve months, indicating positive momentum in its biotech holdings.
Leading Biotech Companies in Top Holdings
Several major positions like Amgen, Biogen, and Vertex have delivered solid year-to-date performance, helping support the fund’s returns.
Focused Exposure to Innovative Health Care
Almost all assets are invested in U.S. health care and biotech companies, giving investors targeted exposure to a high-innovation sector.
Negative Factors
High Sector Concentration
With nearly all assets in health care and biotech, the fund is heavily exposed to swings in one industry rather than being broadly diversified.
Mixed Performance Among Top Holdings
Some key holdings like Regeneron and Alnylam have shown weak year-to-date performance, which can drag on overall fund results.
Above-Average Expense Ratio
The fund’s fee is higher than many broad market ETFs, which means more of the returns are used to cover costs.

PBE vs. SPDR S&P 500 ETF (SPY)

PBE Summary

PBE is the Invesco Dynamic Biotechnology & Genome ETF, which follows the Dynamic Biotech & Genome Intellidex Index. It focuses on U.S. health care companies working in biotechnology and genetics, including well-known names like Amgen and Gilead Sciences. Investors might consider PBE if they want growth potential from new medical treatments and drugs, while spreading their money across many biotech firms instead of picking single stocks. However, biotech stocks can be very volatile, often moving sharply on drug trial news or regulation changes, so the ETF’s price can go up and down a lot.
How much will it cost me?The expense ratio for the Invesco Dynamic Biotechnology & Genome ETF (PBE) is 0.58%, which means you’ll pay $5.80 per year for every $1,000 invested. This is higher than average because the fund is actively managed, focusing on specialized biotechnology and genomic research companies that require more in-depth analysis and management.
What would affect this ETF?The Invesco Dynamic Biotechnology & Genome ETF (PBE) could benefit from advancements in biotechnology and genomic research, as well as increased demand for innovative healthcare solutions. However, it may face challenges from regulatory changes, high research and development costs, or economic downturns that could impact funding for biotech companies. The ETF’s focus on U.S.-based firms and top holdings like Vertex Pharmaceuticals and Gilead Sciences highlights its reliance on the performance of leading biotech innovators.

PBE Top 10 Holdings

PBE is a pure-play U.S. biotech fund, and its story is all about a few big science names setting the tone. Royalty Pharma and a surging CareDx have been the real engines, giving the ETF a lift as their shares keep climbing. Amgen and Biogen are also pulling their weight, staying generally upbeat despite some bumps. On the flip side, Regeneron and Alnylam feel more like headwinds, with recent weakness dulling some of the fund’s shine. With nearly everything in health care, this ETF lives and dies by biotech’s mood swings.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Amgen5.08%$14.38M$202.95B24.88%
77
Outperform
Vertex Pharmaceuticals4.98%$14.11M$121.16B3.94%
78
Outperform
Royalty Pharma4.95%$14.00M$33.88B58.47%
79
Outperform
Regeneron4.77%$13.50M$68.78B19.43%
78
Outperform
Biogen4.70%$13.31M$29.85B54.81%
74
Outperform
Gilead Sciences4.43%$12.53M$160.55B15.47%
78
Outperform
Alnylam Pharma4.27%$12.10M$36.28B-14.28%
60
Neutral
CareDx4.18%$11.82M$1.92B184.28%
77
Outperform
United Therapeutics4.14%$11.72M$22.43B77.08%
79
Outperform
Bio-Techne3.69%$10.46M$11.21B22.32%
64
Neutral

PBE Technical Analysis

Technical Analysis Sentiment
Positive
Last Price
Price Trends
50DMA
86.48
Positive
100DMA
82.59
Positive
200DMA
80.70
Positive
Market Momentum
MACD
RSI
STOCH
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For PBE, the sentiment is Positive. The current price of undefined is equal to the 20-day moving average (MA) of 90.85, equal to the 50-day MA of 86.48, and equal to the 200-day MA of 80.70, indicating a bullish trend. The MACD of ― indicates undefined momentum. The RSI at ― is undefined, neither overbought nor oversold. The STOCH value of ― is undefined, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PBE.

PBE Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$288.75M0.58%
71
Outperform
$744.69M0.40%
71
Outperform
$478.93M0.35%
56
Neutral
$453.30M0.57%
69
Neutral
$368.74M0.51%
65
Neutral
$204.25M0.50%
47
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PBE
Invesco Dynamic Biotechnology & Genome ETF
91.13
27.07
42.26%
RSPH
Invesco S&P 500 Equal Weight Health Care ETF
XPH
SPDR S&P Pharmaceuticals ETF
PJP
Invesco Dynamic Pharmaceuticals ETF
PINK
Simplify Health Care ETF
SBIO
ALPS Medical Breakthroughs ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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