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BioCryst
(NASDAQ:BCRX)
BioCryst (BCRX) vs. SPDR S&P 500 ETF (SPY)
BioCryst Business Overview & Revenue Model
BioCryst Key Performance Indicators (KPIs)
Analyzes revenue from different business segments, offering insight into which parts of BioCryst's operations are most profitable and where there may be opportunities or challenges.
Main Street DataBioCryst Earnings Call Summary
BioCryst Financial Statement Overview
| Breakdown | TTM | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 503.49M | 450.71M | 331.41M | 270.83M | 157.17M | 17.81M |
| Gross Profit | 487.82M | 438.44M | 325.10M | 262.80M | 149.13M | 16.14M |
| EBITDA | 43.80M | 12.81M | -116.33M | -143.85M | -121.74M | -167.56M |
| Net Income | -53.47M | -88.88M | -226.54M | -247.12M | -184.06M | -182.81M |
Balance Sheet | ||||||
| Total Assets | 480.05M | 490.42M | 516.96M | 550.00M | 588.15M | 334.71M |
| Cash, Cash Equivalents and Short-Term Investments | 295.09M | 320.85M | 388.99M | 424.31M | 507.60M | 300.37M |
| Total Debt | 794.99M | 841.42M | 848.71M | 741.45M | 593.24M | 279.50M |
| Total Liabilities | 931.97M | 966.35M | 972.49M | 844.60M | 695.14M | 353.98M |
| Stockholders Equity | -451.93M | -475.93M | -455.53M | -294.60M | -106.99M | -19.26M |
Cash Flow | ||||||
| Free Cash Flow | -27.29M | -53.14M | -97.31M | -163.20M | -144.54M | -137.73M |
| Operating Cash Flow | -26.25M | -52.02M | -95.14M | -161.85M | -142.16M | -137.22M |
| Investing Cash Flow | 50.93M | 52.59M | -131.50M | -128.24M | 15.80M | -6.86M |
| Financing Cash Flow | -4.18M | -5.76M | 32.48M | 88.03M | 359.67M | 300.59M |
BioCryst Technical Analysis
BioCryst Risk Analysis
BioCryst Peers Comparison
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
61 Neutral | $1.14B | 33.85 | -35.00% | ― | 21.48% | 162.30% | |
58 Neutral | $2.13B | 3.32 | 64.05% | ― | 30.57% | ― | |
53 Neutral | $2.85B | ― | -33.26% | ― | -49.51% | -44.09% | |
51 Neutral | $7.44B | -0.20 | -46.00% | 2.27% | 22.80% | -2.27% | |
50 Neutral | $1.75B | ― | 18.68% | ― | 45.85% | 76.36% | |
47 Neutral | $2.46B | ― | -34.80% | ― | 2816.21% | 73.33% | |
43 Neutral | $2.05B | ― | -26.36% | ― | ― | -22.19% |
BioCryst Corporate Events
On August 6, 2025, Dr. Helen Thackray announced her resignation as Chief Research and Development Officer of BioCryst Pharmaceuticals, effective September 1, 2025, after not being selected as the next CEO. The company has entered into a Separation Agreement with Dr. Thackray, offering various benefits, and a Consulting Agreement for transition services until the end of 2025, ensuring a smooth transition and continuity in operations.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
In the second quarter of 2025, BioCryst Pharmaceuticals reported a significant financial performance with ORLADEYO net revenue reaching $156.8 million, a 45% increase year-over-year, and an operating profit of $29.8 million, marking a 239% rise. The company also announced plans to retire its remaining term debt through the sale of its European ORLADEYO business, which is expected to further strengthen its financial position. The growth in ORLADEYO’s demand, particularly in the U.S., and the promising pipeline developments, including new drug applications and ongoing trials, highlight BioCryst’s strategic focus on expanding its market presence and delivering value to stakeholders.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On July 31, 2025, BioCryst Pharmaceuticals announced the retirement of Jon Stonehouse as President and CEO, effective December 31, 2025, with Charlie Gayer appointed as the new President effective August 1, 2025, and CEO starting January 1, 2026. Gayer, who has been instrumental in the commercial success of ORLADEYO and shaping the company’s business strategy, is expected to continue driving growth and value creation for stakeholders.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On July 7, 2025, BioCryst Pharmaceuticals announced the appointment of Babar Ghias as Chief Financial Officer and Head of Corporate Development. Mr. Ghias brings extensive experience from his previous roles at AvenCell Therapeutics and Paragon Biosciences, where he was instrumental in launching biotechnology companies and raising significant capital. His appointment is expected to bolster BioCryst’s leadership team as the company aims to accelerate growth and enhance value creation. This strategic move is seen as pivotal for BioCryst’s operational excellence and financial discipline, supporting its ambitious growth plans.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On June 27, 2025, BioCryst Pharmaceuticals entered into a Stock Purchase Agreement to sell its equity interests in BioCryst Ireland to Neopharmed Gentili S.p.A. for $250 million, with potential additional payments based on revenue milestones. This transaction, expected to close in October 2025, will involve amendments to existing intellectual property agreements and establish BioCryst as the exclusive supplier of ORLADEYO® to the company, impacting BioCryst’s operations and market positioning in Europe.
The most recent analyst rating on (BCRX) stock is a Buy with a $11.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On June 27, 2025, BioCryst Pharmaceuticals announced the sale of its European ORLADEYO business to Neopharmed Gentili for up to $264 million. The transaction will allow BioCryst to eliminate its remaining term debt, saving approximately $70 million in future interest payments, and is expected to leave the company with $700 million in cash by the end of 2027. This strategic move aligns with BioCryst’s goal of enhancing profitability and sustaining growth, while Neopharmed Gentili aims to strengthen its position in the European specialty pharmaceutical market.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On June 23, 2025, the FDA extended the PDUFA goal date for BioCryst‘s new drug application for ORLADEYO® oral granules for pediatric HAE patients aged 2 to 11. This extension, moving the target action date to December 12, 2025, was due to the submission of additional reports and data, which the FDA considered a major amendment requiring a full review.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On June 11, 2025, George B. Abercrombie announced his retirement from BioCryst‘s Board of Directors, effective at the 2025 Annual Meeting. The company expressed gratitude for his 13 years of service. On June 12, 2025, BioCryst’s stockholders approved an amendment to the Stock Incentive Plan, increasing available shares by 11 million. The meeting also included the election of directors, ratification of Ernst & Young LLP as accountants, and approval of executive compensation.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
BioCryst Pharmaceuticals extended a Consulting Agreement with its former CFO, Anthony Doyle, to ensure a smooth transition in leadership. The agreement, effective April 9, 2025, and extended on May 31, 2025, will continue on a month-to-month basis after December 31, 2025, providing stability during the CFO transition.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.
On May 14, 2025, BioCryst Pharmaceuticals announced that the FDA accepted its new drug application for ORLADEYO® oral granules for pediatric patients with hereditary angioedema aged 2 to 11 years, granting it priority review with a target action date of September 12, 2025. If approved, ORLADEYO would be the first targeted oral prophylactic therapy for this age group, potentially improving disease management and reducing acute attacks, with additional regulatory filings planned in Europe, Japan, and Canada.
The most recent analyst rating on (BCRX) stock is a Buy with a $13.00 price target. To see the full list of analyst forecasts on BioCryst stock, see the BCRX Stock Forecast page.