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Mannkind Corp. (MNKD)
NASDAQ:MNKD
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MannKind (MNKD) AI Stock Analysis

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MNKD

MannKind

(NASDAQ:MNKD)

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Neutral 64 (OpenAI - 4o)
Rating:64Neutral
Price Target:
$6.50
▲(15.45% Upside)
MannKind's overall stock score reflects a mix of strengths and challenges. The most significant factor is the company's strong revenue growth and strategic acquisitions, as highlighted in the earnings call. Technical analysis supports a positive outlook with bullish momentum. However, the high P/E ratio and balance sheet concerns, including negative equity, weigh on the score.
Positive Factors
Revenue Growth
Record revenue growth indicates strong demand and successful product performance, particularly from Tyvaso DPI and Afrezza, supporting long-term business expansion.
Strategic Acquisitions
The acquisition of scPharmaceuticals expands MannKind's product portfolio into cardiorenal medicine, enhancing its market position and growth potential in new therapeutic areas.
Cash Flow Generation
Strong cash flow generation supports MannKind's ability to fund operations and strategic initiatives, ensuring financial stability and flexibility for future growth.
Negative Factors
Balance Sheet Health
Negative equity and high leverage pose risks to financial stability, potentially limiting MannKind's ability to invest in growth and manage economic downturns.
SG&A Expenses
Rising SG&A expenses could pressure margins and profitability, necessitating careful management to maintain operational efficiency and long-term financial health.
VGo Revenue Decline
Declining VGo revenue reflects challenges in product demand, potentially affecting overall revenue diversification and necessitating strategic adjustments.

MannKind (MNKD) vs. SPDR S&P 500 ETF (SPY)

MannKind Business Overview & Revenue Model

Company DescriptionMannKind Corporation, a biopharmaceutical company, focuses on the development and commercialization of inhaled therapeutic products for endocrine and orphan lung diseases in the United States. It offers Afrezza, an inhaled insulin used to improve glycemic control in adults with diabetes. It also promotes Thyquidity to adult and pediatric endocrinologists, and other healthcare providers for the treatment of hypothyroidism. The company has a license and collaboration agreement with United Therapeutics Corporation. It also has an agreement with NRx Pharmaceuticals to develop a dry powder formulation of ZYESAMI (aviptadil), a synthetic form of human vasoactive intestinal peptide to help protect cells against inflammatory conditions. MannKind Corporation was incorporated in 1991 and is headquartered in Westlake Village, California.
How the Company Makes MoneyMannKind generates revenue primarily through the sales of Afrezza, which is marketed to patients with diabetes requiring insulin therapy. The company earns money from the direct sale of Afrezza to pharmacies and healthcare providers, as well as from partnerships with pharmaceutical distributors. Additionally, MannKind may receive royalties and milestone payments from collaborations with other companies that utilize its Technosphere technology for their own drug formulations. The company’s revenue model is heavily impacted by the demand for Afrezza, market competition, and ongoing marketing efforts to educate both healthcare professionals and patients about the benefits of inhaled insulin.

MannKind Earnings Call Summary

Earnings Call Date:Nov 05, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue performance driven by Tyvaso DPI and Afrezza, alongside strategic growth initiatives such as the acquisition of scPharmaceuticals. However, challenges such as a decline in VGo revenue and increased SG&A expenses were noted. Overall, the positive aspects of revenue growth and strategic acquisitions outweighed the lowlights.
Q3-2025 Updates
Positive Updates
Record Revenue in Q3 2025
MannKind Corporation delivered a record revenue quarter of $82 million, primarily driven by strong performance from Tyvaso DPI and Afrezza.
Acquisition of scPharmaceuticals
MannKind completed the acquisition of scPharmaceuticals, enhancing its portfolio and expanding its footprint into cardiorenal medicine.
Strong Performance of Tyvaso DPI
Tyvaso DPI generated $33 million in royalties and $26 million in manufacturing-related revenue, marking the highest revenue quarter for the product.
FUROSCIX Revenue Growth
FUROSCIX revenue reached $47.1 million year-to-date, a 95% increase over the same period in 2024, with over 27,000 doses dispensed in Q3 2025, up 153% from the previous year.
Afrezza Prescription Growth
Afrezza saw a 31% increase in new prescriptions and a 27% increase in total prescriptions year-over-year, with net revenue up 23% in Q3 2025 compared to Q3 2024.
Negative Updates
VGo Revenue Decline
VGo contributed $3.8 million in Q3, down 19% over the prior year period, as the company no longer actively promotes the product.
High SG&A Expenses
Selling, general, and administrative expenses increased by $5.2 million or 22% in the third quarter versus the prior year period, driven by investments in Afrezza and acquisition-related expenses.
GAAP Net Income Decrease
GAAP net income for Q3 2025 was $8 million, compared to $11.6 million in the prior year, indicating a decrease despite strong revenue growth.
Company Guidance
In the MannKind Corporation's third-quarter 2025 earnings call, CEO Michael Castagna highlighted several key metrics and developments. The company achieved a record revenue of $82 million, with significant contributions from Tyvaso DPI, generating $59 million in royalty and manufacturing revenue. MannKind's recent acquisition of scPharmaceuticals aims to enhance its portfolio, particularly with FUROSCIX, which saw a 153% increase in doses dispensed year-over-year. The Afrezza segment reported a 23% revenue increase compared to Q3 2024, although a 15% decline in units per script was noted as the focus shifted toward type 1 diabetes and pediatrics. Additionally, a supplemental BLA for Afrezza was accepted, with a PDUFA date set for Q2 2026. MannKind is also advancing its pipeline with the sNDA submission for FUROSCIX auto-injector, expected to receive a PDUFA date in Q3 2026, and is working on expanding its Technosphere technology applications. Financially, the company reported a 17% revenue growth over the prior year, with non-GAAP net income of $22.4 million, reflecting a strong operational performance despite increased investments in growth drivers.

MannKind Financial Statement Overview

Summary
MannKind's financial performance is mixed. The income statement shows growth and improved profitability, with a strong gross profit margin of 74.91% and a net profit margin of 10.87%. The cash flow statement highlights robust cash generation capabilities with a 50.72% increase in free cash flow. However, the balance sheet presents significant challenges, including negative stockholders' equity and high financial leverage, posing potential risks.
Income Statement
65
Positive
MannKind's income statement shows a positive trajectory with a consistent increase in total revenue and gross profit margins over the years. The TTM data reflects a gross profit margin of 74.91% and a net profit margin of 10.87%, indicating improved profitability. However, the EBIT and EBITDA margins have slightly decreased compared to the previous year, suggesting some operational challenges. Overall, the revenue growth rate of 3.99% in the TTM period is a positive indicator of growth.
Balance Sheet
40
Negative
The balance sheet reveals significant challenges with a negative stockholders' equity, leading to a negative debt-to-equity ratio. This indicates high financial leverage and potential risk. The return on equity is also negative, reflecting the company's struggle to generate profits from its equity base. Despite a stable asset base, the negative equity ratio is a concern for long-term financial stability.
Cash Flow
70
Positive
Cash flow analysis shows a strong improvement in free cash flow growth at 50.72% in the TTM period, indicating better cash generation capabilities. The operating cash flow to net income ratio is positive, suggesting efficient cash conversion from operations. The free cash flow to net income ratio of 83.33% further supports the company's ability to generate cash relative to its net income, showcasing a healthy cash flow position.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue313.79M285.50M198.96M99.77M75.44M65.14M
Gross Profit240.39M208.90M136.19M42.27M36.59M40.50M
EBITDA74.15M77.47M15.13M-56.34M-61.09M-45.01M
Net Income29.23M27.59M-11.94M-112.17M-91.79M-57.24M
Balance Sheet
Total Assets494.64M393.84M475.20M295.28M321.16M108.61M
Cash, Cash Equivalents and Short-Term Investments260.04M197.26M295.10M170.85M204.12M67.00M
Total Debt46.48M47.70M382.38M382.91M382.74M123.44M
Total Liabilities539.19M472.66M721.37M545.82M530.51M289.03M
Stockholders Equity-44.55M-78.82M-246.17M-250.54M-209.35M-180.42M
Cash Flow
Free Cash Flow43.39M32.82M-8.35M-88.27M-73.17M-32.91M
Operating Cash Flow48.86M42.51M34.09M-80.68M-61.71M-28.13M
Investing Cash Flow35.38M-96.65M-1.99M4.87M-151.54M15.22M
Financing Cash Flow-19.21M-137.27M136.61M21.41M270.27M49.85M

MannKind Technical Analysis

Technical Analysis Sentiment
Positive
Last Price5.63
Price Trends
50DMA
5.44
Positive
100DMA
4.64
Positive
200DMA
4.78
Positive
Market Momentum
MACD
0.11
Negative
RSI
54.29
Neutral
STOCH
55.49
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MNKD, the sentiment is Positive. The current price of 5.63 is above the 20-day moving average (MA) of 5.47, above the 50-day MA of 5.44, and above the 200-day MA of 4.78, indicating a bullish trend. The MACD of 0.11 indicates Negative momentum. The RSI at 54.29 is Neutral, neither overbought nor oversold. The STOCH value of 55.49 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MNKD.

MannKind Risk Analysis

MannKind disclosed 50 risk factors in its most recent earnings report. MannKind reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

MannKind Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$1.86B60.4517.44%24.15%
52
Neutral
$1.55B-5.38%26.90%62.72%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$1.48B45.38%92.85%
45
Neutral
$1.82B-21.37%47.15%-311.26%
38
Underperform
$1.58B-27.17%-30.25%-9.70%
37
Underperform
$1.97B-95.40%4.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MNKD
MannKind
5.63
-1.71
-23.30%
BCRX
BioCryst
7.09
-0.69
-8.87%
CLDX
Celldex
22.90
-3.32
-12.66%
SRPT
Sarepta Therapeutics
17.63
-103.98
-85.50%
COGT
Cogent Biosciences
14.82
4.61
45.15%
IMCR
Immunocore Holdings
33.50
-1.19
-3.43%

MannKind Corporate Events

MannKind Corporation Reports Strong Q3 2025 Growth
Nov 6, 2025

MannKind Corporation is a biopharmaceutical company focused on developing and commercializing innovative therapies for chronic diseases, particularly in the cardiometabolic and orphan lung disease sectors. In its third quarter of 2025, MannKind reported a revenue increase of 17% compared to the same period in 2024, reaching $82.1 million. The company also completed the acquisition of scPharmaceuticals, which is expected to accelerate revenue growth through FUROSCIX, a therapy for edema associated with chronic heart failure and kidney disease. Key financial highlights include a 23% increase in Afrezza sales and a 14% year-to-date revenue growth. MannKind’s strategic initiatives include the FDA’s acceptance of Afrezza’s pediatric sBLA, the submission of FUROSCIX ReadyFlow Autoinjector sNDA, and progress in clinical trials for MNKD-101 and MNKD-201. Looking ahead, MannKind’s management remains optimistic about the company’s growth prospects, driven by its diversified portfolio and ongoing clinical developments.

MannKind’s Record Q3 2025 Earnings and Strategic Moves
Nov 6, 2025

MannKind Corporation’s recent earnings call painted a picture of robust growth and strategic expansion, despite some challenges. The company reported strong revenue performance, largely driven by Tyvaso DPI and Afrezza, and highlighted strategic growth initiatives such as the acquisition of scPharmaceuticals. Although there were challenges like a decline in VGo revenue and increased SG&A expenses, the positive aspects of revenue growth and strategic acquisitions were more prominent.

Business Operations and StrategyM&A Transactions
MannKind Completes Acquisition of scPharma
Positive
Oct 9, 2025

On October 7, 2025, MannKind completed the acquisition of scPharma, making it a wholly-owned subsidiary. This acquisition was facilitated through a merger agreement and involved a contingent value rights agreement, which outlines milestone payments based on FDA approval and sales targets. The acquisition was funded by MannKind’s available cash and borrowings under a credit agreement, with a total transaction cost of approximately $296.5 million. The merger aims to enhance MannKind’s market position by integrating scPharma’s drug-device combination products and leveraging potential sales growth.

The most recent analyst rating on (MNKD) stock is a Buy with a $11.00 price target. To see the full list of analyst forecasts on MannKind stock, see the MNKD Stock Forecast page.

MannKind Corporation’s Phase 3 Study: A Potential Game-Changer for Nontuberculous Mycobacterial Infections
Sep 7, 2025

Study Overview: MannKind Corporation is conducting a Phase 3 clinical study titled ICoN-1: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Efficacy and Safety of Clofazimine Inhalation Suspension When Added to Guideline-Based Therapy in Participants With Nontuberculous Mycobacterial Infection. The study aims to evaluate the efficacy and safety of Clofazimine Inhalation Suspension compared to a placebo in treating nontuberculous mycobacterial infections, which are notoriously difficult to treat and can significantly impact patient health.

Business Operations and StrategyProduct-Related Announcements
MannKind Amends License Agreement with United Therapeutics
Positive
Aug 27, 2025

On August 24, 2025, MannKind Corporation amended its global license agreement with United Therapeutics to include an additional development product. MannKind will use its Technosphere® platform to formulate an investigational molecule and manufacture clinical trial materials, while United Therapeutics will handle preclinical and clinical development. MannKind will receive a $5 million upfront payment, up to $35 million in milestone payments, and 10% royalties on net sales if the product is approved.

The most recent analyst rating on (MNKD) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on MannKind stock, see the MNKD Stock Forecast page.

Business Operations and StrategyM&A Transactions
MannKind Announces Acquisition of scPharmaceuticals
Positive
Aug 25, 2025

On August 24, 2025, MannKind Corporation announced a definitive merger agreement to acquire scPharmaceuticals Inc. for $5.35 per share in cash and a contingent value right (CVR) worth up to $1.00 per share. This acquisition is expected to diversify and accelerate MannKind’s revenue growth, particularly with the FUROSCIX product, and strengthen its position in cardiometabolic and lung diseases. The merger is anticipated to close in the fourth quarter of 2025, subject to regulatory approvals, and aims to integrate scPharmaceuticals’ commercial capabilities into MannKind’s existing infrastructure, potentially expanding market opportunities and creating value for stakeholders.

The most recent analyst rating on (MNKD) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on MannKind stock, see the MNKD Stock Forecast page.

MannKind Corporation’s Earnings Call Highlights Growth and Challenges
Aug 8, 2025

MannKind Corporation’s recent earnings call showcased a positive sentiment, driven by robust financial metrics and promising developments in their product pipeline. The company reported significant growth in Tyvaso DPI and Afrezza revenues, although challenges were noted in V-Go revenue and manufacturing timing. Despite these hurdles, the outlook remains optimistic with strategic plans and financial resources poised to support future growth.

MannKind Corporation Reports Q2 2025 Financial Growth
Aug 7, 2025

MannKind Corporation is a pharmaceutical company specializing in the development and commercialization of inhaled therapeutic products, primarily targeting endocrine and orphan lung diseases.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 06, 2025