Clinical Program DiscontinuationAnalyst reports that discontinuation of the MNKD‑101 trial for nebulized clofazimine due to futility removes a potential development asset and reduces pipeline optionality and future revenue prospects.
Execution And Partner RiskAnalyst flags commercial execution difficulties, clinical trial failures, regulatory setbacks, and reliance on a commercialization partner as key risks that could limit revenue realization.
Under‑dosing Efficacy ReportsReal‑world reports linking Afrezza's perceived lack of efficacy to under‑dosing underscore the need for clearer dosing guidance and could slow adoption if not resolved.