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Biogen (BIIB)
NASDAQ:BIIB

Biogen (BIIB) AI Stock Analysis

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BIIB

Biogen

(NASDAQ:BIIB)

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Outperform 74 (OpenAI - 4o)
Rating:74Outperform
Price Target:
$168.00
▲(2.18% Upside)
Biogen's overall stock score is driven by strong technical momentum and positive earnings call insights, highlighting growth in new products and a robust pipeline. Financial performance shows resilience, though challenges in revenue growth and declining margins persist. Valuation is moderate, with no dividend yield.
Positive Factors
Pipeline Advancements
Biogen's initiation of multiple Phase III studies indicates a robust pipeline, which is crucial for long-term growth and maintaining competitive advantage in the biotech industry.
Cash Flow Management
Strong cash flow management enhances Biogen's ability to invest in R&D and strategic initiatives, supporting sustainable growth and financial resilience.
Strategic Collaborations
Strategic collaborations, like the agreement with Vanqua, expand Biogen's portfolio and enhance its R&D capabilities, positioning it for long-term success in the biotech sector.
Negative Factors
Declining Profitability Margins
Declining profitability margins suggest challenges in cost management and operational efficiency, which could impact Biogen's long-term financial health and competitiveness.
MS Revenue Challenges
Competitive pressures in the MS market, particularly from generics, threaten Biogen's revenue streams and market position, potentially affecting long-term growth.
Arbitration with Eisai
The arbitration with Eisai highlights potential partnership challenges, which could disrupt strategic collaborations and impact Biogen's market strategy in Europe.

Biogen (BIIB) vs. SPDR S&P 500 ETF (SPY)

Biogen Business Overview & Revenue Model

Company DescriptionBiogen Inc. discovers, develops, manufactures, and delivers therapies for treating neurological and neurodegenerative diseases. The company offers TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI, and FAMPYRA for multiple sclerosis (MS); SPINRAZA for spinal muscular atrophy; and FUMADERM to treat plaque psoriasis. It also provides BENEPALI, an etanercept biosimilar referencing ENBREL; ADUHELM for the treatment of Alzheimer's disease; IMRALDI, an adalimumab biosimilar referencing HUMIRA; and FLIXABI, an infliximab biosimilar referencing REMICADE. In addition, the company offers RITUXAN for treating non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, two forms of ANCA-associated vasculitis, and pemphigus vulgaris; RITUXAN HYCELA for non-Hodgkin's lymphoma and CLL; GAZYVA to treat CLL and follicular lymphoma; and OCREVUS for treating relapsing MS and primary progressive MS; and other anti-CD20 therapies. Further, it develops BIIB135, BIIB061, BIIB091, and BIIB107 for MS and neuroimmunology; Aducanumab, Lecanemab, BIIB076, and BIIB080 to treat Alzheimer's disease and dementia; BIIB067, BIIB078, BIIB105, BIIB100, and BIIB110 to treat neuromuscular disorders; BIIB124, BIIB094, BIIB118, BIIB101, and BIIB122 for treating Parkinson's disease and movement disorders; BIIB125 and BIIB104 for treating neuropsychiatry; Dapirolizumab pegol and BIIB059 to treat immunology related diseases; BIIB093 and BIIB131 to treat acute neurology; BIIB074 for neuropathic pain; and BYOOVIZ, BIIB800, and SB15 biosimilars, which are under various stages of development. The company has collaboration and license agreements with Acorda Therapeutics, Inc.; Alkermes Pharma Ireland Limited; Denali Therapeutics Inc.; Eisai Co., Ltd.; Genentech, Inc.; Neurimmune SubOne AG; Ionis Pharmaceuticals, Inc.; Samsung Bioepis Co., Ltd.; Sangamo Therapeutics, Inc.; and Sage Therapeutics, Inc. Biogen Inc. was founded in 1978 and is headquartered in Cambridge, Massachusetts.
How the Company Makes MoneyBiogen generates revenue primarily through the sale of its pharmaceutical products, particularly those targeting neurological disorders. The company's key revenue streams include sales from its multiple sclerosis therapies, which account for a significant portion of its income. Additionally, Biogen earns revenue from royalties and collaborations with other pharmaceutical companies, often involving joint ventures or co-development agreements for new therapies. Their partnership with companies like Eisai for Alzheimer's treatments also plays a crucial role in their financial strategy. Furthermore, Biogen invests in research and development to create new drugs, which, once approved, can significantly enhance its product portfolio and drive future revenues.

Biogen Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where Biogen is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsBiogen's U.S. revenue shows a gradual recovery since 2023, while international revenue faces challenges, likely due to competitive pressures and inventory issues. The earnings call highlights strong growth from new product launches, particularly LEQEMBI, which offsets declines in other areas. Despite international hurdles, Biogen's raised EPS guidance and promising pipeline developments suggest a positive long-term outlook. Investors should watch for the impact of competitive pressures in the ex-US market, especially for TECFIDERA, and potential financial implications from the arbitration with Eisai.
Data provided by:The Fly

Biogen Earnings Call Summary

Earnings Call Date:Oct 30, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 06, 2026
Earnings Call Sentiment Positive
Biogen's earnings call reflected a strong performance in new product launches and pipeline progress, with significant revenue growth in key segments offsetting some challenges, particularly in Europe and China. The financial results and strategic focus on pipeline expansion suggest a positive outlook.
Q3-2025 Updates
Positive Updates
Strong Revenue Growth in Launch Products
Biogen's launch products demonstrated a year-on-year growth of 67% in Q3 2025, significantly offsetting the decline in MS revenue.
LEQEMBI Sales and Global Demand
LEQEMBI continues to show strong global demand with Q3 sales of $121 million and positive feedback from customers and payers.
Pipeline Progress
Litifilimab Phase III studies in SLE are fully enrolled with expected readouts in 2026, indicating strong commercial potential.
ZURZUVAE Revenue Growth
ZURZUVAE saw a 19% revenue growth compared to the previous quarter, driven by increased demand and new prescribers.
Financial Performance
Biogen delivered a 3% revenue growth overall, with non-GAAP diluted EPS growth of 18% and $1.2 billion in free cash flow in Q3 2025.
Negative Updates
TECFIDERA Generic Erosion in Europe
Accelerated erosion in TECFIDERA revenue due to generic launches in Europe, including Germany, with a sequential net decrease of $28 million.
Challenges in China for LEQEMBI
Negligible LEQEMBI sales in China for Q3 due to a $35 million inventory build in the prior quarter, impacting current quarter sales.
U.S. SKYCLARYS Revenue Impact
In the U.S., SKYCLARYS revenue was impacted by a $6 million adjustment related to channel mix and IRA changes to Medicare.
Company Guidance
During Biogen's Third Quarter 2025 Earnings Call, the company provided guidance highlighting significant growth across its portfolio. Key metrics included a 67% year-over-year growth in launch products, with LEQEMBI sales reaching $121 million globally. SKYCLARYS showed a 30% revenue growth year-over-year, while ZURZUVAE achieved a remarkable 150% revenue growth in the same period. The company's late-stage pipeline is robust, with 10 Phase III or Phase III-ready programs, and they are expanding their early-stage pipeline with assets like BIIB142 for autoimmune diseases. The financial guidance was updated to reflect a stronger business outlook, with anticipated sales growth of up to 1% at constant currency and a focus on business development activities impacting non-GAAP EPS guidance by approximately $1.25 per share. Biogen also emphasized its commitment to delivering $1 billion in gross savings as part of the Fit-for-Growth initiative by the end of 2025.

Biogen Financial Statement Overview

Summary
Biogen's financial performance shows resilience with a strong balance sheet and improving cash flow generation. However, challenges in revenue growth and declining margins impact overall profitability. The company maintains a solid capital structure and effective cash management.
Income Statement
65
Positive
Biogen's income statement shows a mixed performance. The TTM gross profit margin is strong at 56.76%, but has decreased from previous years, indicating some pressure on cost management. The net profit margin is healthy at 15.98%, though it has declined from 29.95% in 2022. Revenue growth has been negative in recent years, but the TTM shows a slight recovery with a 0.69% increase. EBIT and EBITDA margins have also decreased, reflecting reduced operational efficiency.
Balance Sheet
70
Positive
The balance sheet indicates a stable financial position with a debt-to-equity ratio of 0.36 in the TTM, showing a decrease from previous years, which is positive. The return on equity has decreased to 9.25% in the TTM from 22.76% in 2022, suggesting reduced profitability. The equity ratio remains strong, indicating a solid capital structure.
Cash Flow
75
Positive
Cash flow analysis reveals a positive trend with a TTM free cash flow growth rate of 22.66%, indicating improved cash generation. The operating cash flow to net income ratio is 0.75, showing good cash conversion. The free cash flow to net income ratio is high at 0.93, suggesting efficient cash management.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue9.99B9.68B9.84B10.17B10.98B13.44B
Gross Profit7.00B7.37B7.30B7.90B8.87B11.64B
EBITDA3.49B3.00B2.38B3.54B3.92B5.11B
Net Income1.61B1.63B1.16B3.05B1.56B4.00B
Balance Sheet
Total Assets29.21B28.05B26.84B24.55B23.88B24.62B
Cash, Cash Equivalents and Short-Term Investments3.96B2.38B1.05B4.89B3.80B2.61B
Total Debt6.59B6.63B7.34B6.61B7.60B7.83B
Total Liabilities11.00B11.33B12.05B11.17B12.92B13.93B
Stockholders Equity18.21B16.72B14.80B13.40B10.90B10.70B
Cash Flow
Free Cash Flow2.28B2.52B1.24B1.14B3.38B3.81B
Operating Cash Flow2.45B2.88B1.55B1.38B3.64B4.23B
Investing Cash Flow-158.00M-799.20M-4.09B1.59B-563.70M-608.60M
Financing Cash Flow-157.00M-683.50M137.00M-1.76B-2.09B-5.27B

Biogen Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price164.42
Price Trends
50DMA
173.67
Negative
100DMA
159.26
Positive
200DMA
143.31
Positive
Market Momentum
MACD
-0.12
Positive
RSI
35.55
Neutral
STOCH
9.96
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BIIB, the sentiment is Neutral. The current price of 164.42 is below the 20-day moving average (MA) of 176.93, below the 50-day MA of 173.67, and above the 200-day MA of 143.31, indicating a neutral trend. The MACD of -0.12 indicates Positive momentum. The RSI at 35.55 is Neutral, neither overbought nor oversold. The STOCH value of 9.96 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for BIIB.

Biogen Risk Analysis

Biogen disclosed 30 risk factors in its most recent earnings report. Biogen reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Biogen Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
78
Outperform
$150.44B18.7840.53%2.52%2.76%6407.19%
77
Outperform
$177.71B25.5181.71%3.00%11.03%65.22%
77
Outperform
$99.76B13.8235.62%3.41%5.97%128.66%
74
Outperform
$24.73B14.999.31%5.00%-1.03%
73
Outperform
$115.26B19.1233.84%4.84%1.26%
66
Neutral
$383.08B163.55138.53%2.87%7.40%-53.78%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BIIB
Biogen
164.42
23.44
16.63%
AMGN
Amgen
330.41
66.88
25.38%
BMY
Bristol-Myers Squibb
55.26
0.96
1.77%
GILD
Gilead Sciences
124.91
34.48
38.13%
GSK
GlaxoSmithKline
48.22
16.16
50.39%
ABBV
AbbVie
214.35
48.36
29.13%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 22, 2025