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Abbvie (ABBV)
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AbbVie (ABBV) AI Stock Analysis

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ABBV

AbbVie

(NYSE:ABBV)

Rating:75Outperform
Price Target:
$232.00
▲(10.74% Upside)
AbbVie's strong earnings call performance and technical indicators are the most significant factors driving the score. The company's strategic R&D investments and raised guidance reflect confidence in future growth. However, high leverage and valuation concerns temper the overall score. Investors should consider the potential for sustained growth against financial risks and high valuation.
Positive Factors
Clinical Trials
Rinvoq recently reported compelling results from its Phase 3 alopecia areata trial.
Earnings Performance
AbbVie reported a big Q2 beat - with revenues at $15.4B, and EPS of $2.97, both exceeding consensus estimates.
Product Performance
Continued strong outperformance from the company’s foundational growth assets, Skyrizi and Rinvoq, contributing to a 2-3% topline beat.
Revenue Guidance
A second straight raise to revenue guidance, representing an $800mn increase to the prior guide.
Negative Factors
Product Deterioration
More rapid deterioration of Humira counterbalances the upsides in R&S and Vyalev.
Sales Decline
Sales in Aesthetics declined again sequentially due to economic challenges and low consumer sentiment.

AbbVie (ABBV) vs. SPDR S&P 500 ETF (SPY)

AbbVie Business Overview & Revenue Model

Company DescriptionAbbVie Inc. is a global biopharmaceutical company that focuses on the research, development, and commercialization of advanced therapies for complex diseases. Established in 2013 as a spinoff from Abbott Laboratories, AbbVie operates primarily in the sectors of immunology, oncology, neuroscience, and virology. Its core products include the blockbuster drug Humira, which treats autoimmune conditions, as well as other therapies like Imbruvica for cancer and Rinvoq for inflammatory diseases. The company is dedicated to addressing unmet medical needs through innovation and scientific advancement.
How the Company Makes MoneyAbbVie generates revenue primarily through the sale of its pharmaceutical products, with significant contributions from its leading therapies such as Humira, Imbruvica, and Rinvoq. The company's revenue model is largely driven by direct sales to healthcare providers and hospitals, as well as through partnerships and collaborations with other pharmaceutical companies for co-development and marketing. AbbVie also earns revenue through licensing agreements for its proprietary drugs and technologies, which further diversify its income streams. Additionally, the company benefits from a strong pipeline of new therapies that are in various stages of clinical development, enhancing its future revenue potential.

AbbVie Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Analyzes revenue from different business segments, highlighting which areas drive growth and profitability, and indicating strategic focus or diversification.
Chart InsightsAbbVie's Neuroscience segment is experiencing robust growth, reflecting strategic success in this area, with a notable boost from Vraylar and a strong migraine portfolio. Despite challenges in the Aesthetics segment, which faces economic pressures and declining consumer sentiment, the company has raised its full-year revenue guidance due to overall strong performance, particularly from Skyrizi and Rinvoq. The decline in HUMIRA sales due to biosimilar competition is a concern, but the diversified portfolio and R&D advancements are positioning AbbVie for sustained growth.
Data provided by:Main Street Data

AbbVie Earnings Call Summary

Earnings Call Date:Jul 31, 2025
(Q2-2025)
|
% Change Since: 10.67%|
Next Earnings Date:Oct 24, 2025
Earnings Call Sentiment Positive
The earnings call reflects a strong overall performance with significant achievements in revenue growth, pipeline advancement, and strategic acquisitions. However, challenges remain in specific segments such as HUMIRA sales and the aesthetics market.
Q2-2025 Updates
Positive Updates
Strong Financial Performance
Adjusted earnings per share of $2.97, $0.11 above guidance midpoint. Total net revenues were $15.4 billion, exceeding expectations by over $400 million.
Robust Growth in Key Segments
Sales growth of 22% from the ex-HUMIRA platform, with Skyrizi and Rinvoq expected to deliver more than $25 billion in combined sales this year. Neuroscience segment also showed strong double-digit growth driven by Vraylar, Vyalev, and migraine portfolio.
Increased Guidance
Full-year revenue guidance raised by $1.5 billion since the start of the year, now expecting $60.5 billion. Adjusted EPS guidance increased to between $11.88 and $12.08.
Pipeline Advancements
Notable approvals for EMRELIS in non-small cell lung cancer and Rinvoq for GCA. Regulatory submission for TrenibotE in aesthetics and positive Phase III results in alopecia areata.
Strategic Acquisitions and Collaborations
Over 30 business development transactions since last year, including acquisition of Capstan Therapeutics and collaboration with ADARx for siRNA therapies.
Negative Updates
Decline in HUMIRA Sales
HUMIRA global sales down 58.2% due to biosimilar competition, with continued decrease expected as more plans select exclusionary formularies.
Challenges in Aesthetics Market
Aesthetics segment sales down 8% on an operational basis, impacted by economic challenges and lower consumer sentiment.
Competition in Oncology
IMBRUVICA global sales down 9.5% due to competitive dynamics in CLL. Venclexta showing modest growth, but still facing competitive pressures.
Company Guidance
During AbbVie's Second Quarter 2025 Earnings Conference Call, the company reported adjusted earnings per share of $2.97, exceeding the guidance midpoint by $0.11. Total net revenues for the quarter were $15.4 billion, surpassing expectations by over $400 million, with significant contributions from Skyrizi and Rinvoq, which together are projected to achieve more than $25 billion in sales this year. The company raised its full-year revenue guidance by $800 million to $60.5 billion and increased its full-year adjusted earnings per share guidance by $0.21 to a range of $11.88 to $12.08. AbbVie highlighted strong double-digit growth in neuroscience and noted progress in its R&D pipeline, including several late-stage program approvals and strategic acquisitions to bolster its future growth.

AbbVie Financial Statement Overview

Summary
AbbVie shows strong operational profitability with a high gross profit margin, yet faces challenges due to high leverage and modest revenue growth. The balance sheet indicates significant financial risk from high debt levels, while cash flow reflects robust generation but declining free cash flow growth.
Income Statement
75
Positive
AbbVie's income statement reflects strong gross profit margins and a consistent ability to generate EBIT from revenues, indicating operational efficiency. The TTM (Trailing-Twelve-Months) gross profit margin stands at approximately 77.5%, and the EBIT margin is 28.3%, showcasing solid profitability. However, the net profit margin is relatively low at 7.3%, suggesting pressure on net income possibly due to high interest expenses or other non-operating costs. Revenue growth is modest, indicating stable but not rapid growth.
Balance Sheet
65
Positive
The balance sheet reveals significant leverage with a debt-to-equity ratio of 49.2 in the TTM, indicating a high level of debt relative to equity, which could pose financial risk. Return on Equity (ROE) is weak at 295.4%, driven by low equity levels rather than high net income. The equity ratio is low at 1.0%, suggesting limited equity financing and high financial leverage.
Cash Flow
70
Positive
AbbVie has a strong cash flow position with stable free cash flow generation. The operating cash flow to net income ratio is 3.91 in the TTM, indicating robust cash generation relative to net income. However, the free cash flow growth rate is negative at -13.7%, signifying a decline in free cash flow compared to the previous period, which could impact long-term cash sustainability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue57.37B56.33B54.32B58.05B56.20B45.80B
Gross Profit40.55B39.43B33.90B40.64B38.75B30.42B
EBITDA14.82B14.91B17.17B24.17B23.93B12.32B
Net Income4.20B4.28B4.86B11.84B11.54B4.62B
Balance Sheet
Total Assets136.16B135.16B134.71B138.81B146.53B150.56B
Cash, Cash Equivalents and Short-Term Investments5.18B5.55B12.82B9.23B9.83B8.48B
Total Debt69.89B67.84B60.12B64.19B77.58B87.06B
Total Liabilities134.70B131.80B124.31B121.52B131.09B137.47B
Stockholders Equity1.42B3.33B10.36B17.25B15.41B13.08B
Cash Flow
Free Cash Flow15.38B17.83B22.06B24.25B21.99B16.79B
Operating Cash Flow16.40B18.81B22.84B24.94B22.78B17.59B
Investing Cash Flow-11.97B-20.82B-2.01B-623.00M-2.34B-37.56B
Financing Cash Flow-17.29B-5.21B-17.22B-24.80B-19.04B-11.50B

AbbVie Technical Analysis

Technical Analysis Sentiment
Positive
Last Price209.50
Price Trends
50DMA
192.38
Positive
100DMA
188.05
Positive
200DMA
185.94
Positive
Market Momentum
MACD
5.16
Negative
RSI
75.61
Negative
STOCH
83.95
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABBV, the sentiment is Positive. The current price of 209.5 is above the 20-day moving average (MA) of 199.72, above the 50-day MA of 192.38, and above the 200-day MA of 185.94, indicating a bullish trend. The MACD of 5.16 indicates Negative momentum. The RSI at 75.61 is Negative, neither overbought nor oversold. The STOCH value of 83.95 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ABBV.

AbbVie Risk Analysis

AbbVie disclosed 29 risk factors in its most recent earnings report. AbbVie reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbbVie Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
82
Outperform
$143.96B13.4612.16%6.61%14.72%
81
Outperform
$215.01B13.2735.44%3.66%2.00%20.01%
79
Outperform
$245.82B29.6319.76%1.93%15.08%29.15%
78
Outperform
$428.20B19.0230.21%2.80%4.69%34.88%
75
Outperform
$370.09B99.70112.90%3.07%6.05%-29.75%
67
Neutral
$159.11B24.1899.14%3.20%13.10%110.67%
51
Neutral
kr6.13B8.03-27.68%2.19%50.66%15.10%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABBV
AbbVie
210.60
19.98
10.48%
AMGN
Amgen
293.72
-22.49
-7.11%
AZN
AstraZeneca
80.97
-3.87
-4.56%
JNJ
Johnson & Johnson
179.29
19.87
12.46%
MRK
Merck & Company
87.37
-25.10
-22.32%
PFE
Pfizer
25.88
-1.14
-4.22%

AbbVie Corporate Events

Executive/Board ChangesShareholder Meetings
AbbVie Expands Board, Appoints New Independent Director
Neutral
May 13, 2025

On May 9, 2025, AbbVie Inc. expanded its Board of Directors from fourteen to fifteen members, appointing Thomas J. Falk as an independent director and member of the Audit Committee. The Board also announced a future reduction to thirteen directors with the retirement of Richard A. Gonzalez and Glenn F. Tilton on July 1, 2025. Additionally, Robert A. Michael was elected to succeed Mr. Gonzalez as Chairman, with a revised compensation package reflecting his new role. During the 2025 Annual Meeting of Stockholders, several key votes were held, including the election of Class I directors and the ratification of Ernst & Young LLP as the independent accounting firm. However, proposals to amend the certificate of incorporation for voting changes were not approved.

The most recent analyst rating on (ABBV) stock is a Buy with a $190.00 price target. To see the full list of analyst forecasts on AbbVie stock, see the ABBV Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 19, 2025