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Pfizer Inc (PFE)
NYSE:PFE
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Pfizer (PFE) AI Stock Analysis

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PFE

Pfizer

(NYSE:PFE)

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Neutral 64 (OpenAI - 5.2)
Rating:64Neutral
Price Target:
$28.00
â–²(1.60% Upside)
Action:Reiterated
Date:06/19/26
Overall score reflects improving fundamentals and a positive earnings-call outlook (reaffirmed guidance, strong ex‑COVID momentum, cost-savings and pipeline progress), supported by an attractive dividend yield. The rating is held back by only moderate financial statement strength (higher leverage and weaker cash conversion) and a largely neutral technical setup.
Positive Factors
Late-stage R&D success
Multiple positive Phase III readouts materially de‑risk the pipeline, increasing probability of new approvals and label expansions. Over the medium term this supports durable revenue potential, offsets LOE, and strengthens Pfizer’s long‑term product mix and commercial optionality.
Negative Factors
Elevated leverage
Higher leverage reduces balance sheet flexibility and increases financing risk over the medium term. With debt elevated versus pre‑2023 levels, Pfizer has less capacity for large opportunistic M&A or accelerated buybacks without improving cash conversion or reducing net debt, constraining capital allocation optionality.
Read all positive and negative factors
Positive Factors
Negative Factors
Late-stage R&D success
Multiple positive Phase III readouts materially de‑risk the pipeline, increasing probability of new approvals and label expansions. Over the medium term this supports durable revenue potential, offsets LOE, and strengthens Pfizer’s long‑term product mix and commercial optionality.
Read all positive factors

Pfizer Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where Pfizer is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsPfizer's revenue from Emerging and Developed Markets shows a declining trend, while the US market exhibits volatility with recent recovery signs. The earnings call highlights a 10% operational revenue increase, driven by strong product demand and strategic cost management, despite challenges from pricing pressures and competition in oncology. The company's focus on R&D and strategic partnerships, alongside improved EPS guidance, suggests a strategic pivot towards innovation and margin expansion, aiming to counteract geographic revenue declines and enhance long-term shareholder value.
Data provided by:The Fly

Pfizer (PFE) vs. SPDR S&P 500 ETF (SPY)

Pfizer Business Overview & Revenue Model

Company Description
Pfizer Inc. is a global biopharmaceutical leader engaged in the research, development, production, marketing, and distribution of a wide array of medicinal and vaccine products worldwide. Its comprehensive portfolio addresses diverse therapeutic a...
How the Company Makes Money
Pfizer makes money primarily by selling branded prescription pharmaceuticals and vaccines. Revenue is generated when Pfizer supplies products—manufactured internally or through third-party manufacturing partners—to wholesalers, retailers and pharm...

Pfizer Earnings Call Summary

Earnings Call Date:May 05, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 04, 2026
Earnings Call Sentiment Positive
The call conveyed strong operational execution: a revenue and EPS beat, healthy underlying growth ex-COVID (~7%), substantial momentum from launched and acquired products (22% operational growth, $3.1B in Q1), multiple positive clinical readouts and meaningful strategic wins (Vyndamax settlement, favorable Belgian court ruling). Management balanced near-term challenges — LOE dynamics, COVID seasonality, higher accrued royalties and increased R&D spend — with clear actions to drive long-term growth (pipeline advancement, vaccine programs, manufacturing and cost-savings targets, BD capacity). Overall, positives around commercial performance, pipeline progress and legal/cash-flow clarity meaningfully outweigh the manageable near-term headwinds.
Positive Updates
Revenue and EPS Beat in Q1 2026
Total revenues of $14.5 billion in Q1 2026, exceeding expectations and representing a 2% operational increase year-over-year. Reported diluted EPS was $0.47 and adjusted diluted EPS was $0.75, both above expectations.
Negative Updates
Loss of Near-Term Exclusivity (LOE) Headwinds
Management reiterated significant LOE pressures through 2028 and stated leverage may remain around current levels or slightly higher during the transition. While settlement extended exclusivity for Vyndamax and reduced LOE impact, LOEs remain a material multi‑billion-dollar headwind over the coming years (company referenced prior ~$17B now ~ $14–15B).
Read all updates
Q1-2026 Updates
Negative
Revenue and EPS Beat in Q1 2026
Total revenues of $14.5 billion in Q1 2026, exceeding expectations and representing a 2% operational increase year-over-year. Reported diluted EPS was $0.47 and adjusted diluted EPS was $0.75, both above expectations.
Read all positive updates
Company Guidance
Pfizer reaffirmed 2026 guidance, targeting total revenues of $59.5–$62.5 billion and adjusted diluted EPS of $2.80–$3.00, with adjusted gross margins expected in the mid‑70s; that outlook is supported by a strong Q1 showing (revenues $14.5B, +2% operational; ex‑COVID ~+7% operational), Q1 reported EPS $0.47 and adjusted EPS $0.75, adjusted gross margin ~76% and adjusted operating margin 38%. Management emphasized ongoing cost discipline and productivity targets—$7.2B of total net savings by end‑2026 (Phase I savings ~$700M this year, ~$175M realized in Q1)—while noting Q1 metrics such as launch/acquired product revenue $3.1B (+22% op), adjusted Opex $5.5B, operating cash flow $2.6B, leverage ~2.8x, $2.5B invested in R&D, $2.4B returned via dividends, BD capacity of ~ $7B (including ~$1.65B ViiV proceeds) and a $2.6B final TCJA payment; they also flagged assumptions that Paxlovid demand will remain low near term and most Comirnaty sales will be back‑half seasonal, and reiterated a long‑term view of entering a high single‑digit 5‑year revenue CAGR starting in 2029.

Pfizer Financial Statement Overview

Summary
Financials are stabilizing after the post‑2022 reset: TTM revenue has returned to modest growth and margins recovered meaningfully versus 2023 (TTM net margin ~11.8%). Offsetting this, leverage is higher than prior years (debt-to-equity ~0.72) and cash conversion is weaker than ideal (operating cash flow low vs EBIT and FCF trails net income), keeping overall quality moderate.
Income Statement
66
Positive
Balance Sheet
62
Positive
Cash Flow
58
Neutral
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue63.31B62.58B63.63B59.55B100.33B81.29B
Gross Profit43.91B44.01B41.85B30.34B62.09B46.88B
EBITDA16.75B15.10B18.13B9.56B41.03B30.79B
Net Income7.49B7.77B8.02B2.13B31.36B22.15B
Balance Sheet
Total Assets207.62B208.16B213.40B226.50B197.21B181.48B
Cash, Cash Equivalents and Short-Term Investments13.07B13.60B20.48B12.69B22.73B31.07B
Total Debt64.45B67.42B66.99B70.84B34.86B37.00B
Total Liabilities117.21B121.39B124.90B137.21B101.29B104.01B
Stockholders Equity90.10B86.48B88.20B89.01B95.66B77.20B
Cash Flow
Free Cash Flow9.48B9.08B9.84B4.79B26.03B29.87B
Operating Cash Flow11.98B11.71B12.74B8.70B29.27B32.58B
Investing Cash Flow-3.84B-1.35B2.65B-32.28B-15.78B-22.55B
Financing Cash Flow-7.93B-10.30B-17.14B26.07B-14.83B-9.82B

Pfizer Technical Analysis

Technical Analysis Sentiment
Negative
Last Price27.56
Price Trends
50DMA
25.65
Negative
100DMA
26.23
Negative
200DMA
25.26
Negative
Market Momentum
MACD
-0.51
Positive
RSI
32.86
Neutral
STOCH
19.41
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PFE, the sentiment is Negative. The current price of 27.56 is above the 20-day moving average (MA) of 25.18, above the 50-day MA of 25.65, and above the 200-day MA of 25.26, indicating a bearish trend. The MACD of -0.51 indicates Positive momentum. The RSI at 32.86 is Neutral, neither overbought nor oversold. The STOCH value of 19.41 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PFE.

Pfizer Risk Analysis

Pfizer disclosed 26 risk factors in its most recent earnings report. Pfizer reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Pfizer Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
$309.64B35.2317.93%3.12%2.70%-48.28%
71
Outperform
$611.38B29.2926.26%2.50%7.87%-3.56%
71
Outperform
$282.14B22.1231.54%2.87%5.60%9.68%
66
Neutral
$195.01B24.9589.41%3.00%9.94%31.14%
64
Neutral
$136.10B18.238.37%6.65%1.36%-5.39%
61
Neutral
$443.57B123.1068.01%2.87%9.50%-13.63%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PFE
Pfizer
23.88
0.21
0.90%
AMGN
Amgen
361.33
73.14
25.38%
JNJ
Johnson & Johnson
253.98
101.34
66.39%
MRK
Merck & Company
125.37
45.65
57.26%
NVS
Novartis
154.14
32.71
26.94%
ABBV
AbbVie
251.06
66.33
35.91%

Pfizer Corporate Events

Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
Pfizer Reaffirms 2026 Outlook Amid CFO Transition
Positive
Jun 18, 2026
Following its June 18, 2026 announcement of a Chief Financial Officer transition, Pfizer reaffirmed the full-year 2026 financial guidance it first issued on December 16, 2025 and reiterated on May 5, 2026. The company continues to project 2026 rev...
Executive/Board ChangesShareholder Meetings
Pfizer Shareholders Reaffirm Leadership, Governance at 2026 Meeting
Positive
Apr 27, 2026
Pfizer shareholders held their Annual Meeting on April 23, 2026, where they re-elected the full slate of board nominees, including Chief Executive Albert Bourla and other incumbent directors, for terms lasting until the next annual meeting. Invest...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 19, 2026