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Pfizer Inc (PFE)
NYSE:PFE
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Pfizer (PFE) AI Stock Analysis

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PFE

Pfizer

(NYSE:PFE)

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Neutral 66 (OpenAI - 5.2)
Rating:66Neutral
Price Target:
$27.00
â–²(10.02% Upside)
Action:Reiterated
Date:08/04/26
The score is primarily driven by mid-range financial performance: improving TTM revenue and positive cash flow, but with elevated leverage and earnings still well below prior peaks. Technicals add moderate support with mildly bullish momentum and price holding above key moving averages (20/50/200DMA). Valuation is a positive contributor due to the high dividend yield alongside a moderate P/E. The latest earnings call was net supportive on guidance and operational execution, though tempered by impairment-related setbacks, reduced COVID expectations, and LOE/leverage risks.
Positive Factors
Launched & acquired product growth
Sustained double-digit growth from launched and acquired products demonstrates successful portfolio replenishment and commercial execution. That $3.2B tranche growing 18% operationally is a durable revenue engine that can offset post‑COVID declines, supports near‑term revenue stability and aids reinvestment for further launches.
Negative Factors
Elevated leverage
Higher leverage and relatively low operating‑cashflow coverage constrain financial flexibility across a multi‑year LOE transition. With leverage near 2.7x and modest OCF relative to debt, the company faces limited room for large acquisitions or aggressive share repurchase without stronger cash conversion or realized cost savings.
Read all positive and negative factors
Positive Factors
Negative Factors
Launched & acquired product growth
Sustained double-digit growth from launched and acquired products demonstrates successful portfolio replenishment and commercial execution. That $3.2B tranche growing 18% operationally is a durable revenue engine that can offset post‑COVID declines, supports near‑term revenue stability and aids reinvestment for further launches.
Read all positive factors

Pfizer Key Performance Indicators (KPIs)

Any
Any
Revenue by Geography
Revenue by Geography
Breaks down revenue across different regions, revealing where Pfizer is strongest and where it may face risk or growth potential due to local economic conditions or market share shifts.
Chart InsightsPfizer's revenue from Emerging and Developed Markets shows a declining trend, while the US market exhibits volatility with recent recovery signs. The earnings call highlights a 10% operational revenue increase, driven by strong product demand and strategic cost management, despite challenges from pricing pressures and competition in oncology. The company's focus on R&D and strategic partnerships, alongside improved EPS guidance, suggests a strategic pivot towards innovation and margin expansion, aiming to counteract geographic revenue declines and enhance long-term shareholder value.
Data provided by:The Fly

Pfizer (PFE) vs. SPDR S&P 500 ETF (SPY)

Pfizer Business Overview & Revenue Model

Company Description
Pfizer Inc. is a global biopharmaceutical leader engaged in the research, development, production, marketing, and distribution of a wide array of medicinal and vaccine products worldwide. Its comprehensive portfolio addresses diverse therapeutic a...
How the Company Makes Money
Pfizer makes money primarily by selling branded prescription pharmaceuticals and vaccines. Revenue is generated when Pfizer supplies products—manufactured internally or through third-party manufacturing partners—to wholesalers, retailers and pharm...

Pfizer Earnings Call Summary

Earnings Call Date:Aug 04, 2026
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Nov 03, 2026
Earnings Call Sentiment Positive
The call conveyed a generally positive operational and strategic narrative: management beat Q2 revenue and adjusted EPS expectations, raised full-year revenue guidance, highlighted strong growth across launched and acquired products (notably Seagen assets, Padcev, NURTEC, and Eliquis), and outlined robust R&D progress (numerous readouts, pivotal starts and promising clinical data across obesity, oncology and immunology). At the same time, material near-term setbacks were disclosed: a Phase III SV miss that drove a $4.3 billion impairment and a GAAP loss, lower-than-expected COVID revenues (notably Paxlovid), removal of Oxbryta revenue from forecasts, and elevated near-term R&D spend. Management emphasized cost-savings initiatives (now targeting ~ $9.7B through 2029), maintained dividend commitments, and raised confidence in returning to growth by the end of the decade. Overall, positives (revenue/EPS beats, guidance raise, strong launched/acquired product growth, and significant pipeline progress) outweigh the material but specific negatives tied largely to one clinical readout and COVID variability.
Positive Updates
Quarterly Revenue and Underlying Growth
Total Q2 2026 revenue of $15.0 billion, a 1% year-over-year operational increase. Excluding COVID products, the underlying business grew 5% operationally.
Negative Updates
SV Phase III Miss and Large Impairment Charge
Primary overall survival endpoint not met in the ITT population for the SV non-squamous NSCLC Phase III readout. Q2 GAAP results included $4.3 billion in noncash intangible asset impairments (partly tied to the SV readout and removal of Oxbryta revenue projection). Reported GAAP loss per share was -$0.04 for the quarter.
Read all updates
Q2-2026 Updates
Negative
Quarterly Revenue and Underlying Growth
Total Q2 2026 revenue of $15.0 billion, a 1% year-over-year operational increase. Excluding COVID products, the underlying business grew 5% operationally.
Read all positive updates
Company Guidance
Pfizer raised full‑year 2026 revenue guidance to $60.5–$62.5 billion (midpoint up $0.5B) and reaffirmed adjusted diluted EPS of $2.80–$3.00 (which absorbs an ~ $0.10 headwind tied to a $650M acquired IPR&D charge), while trimming 2026 COVID revenue to ~ $4B (from $5B). Management expects adjusted gross margin in the mid‑70s (Q2 was 76%), and Q2 results included $15B revenue (+1% operational; +5% ex‑COVID), $0.77 adjusted diluted EPS (reported loss per share –$0.04), $3.2B in launched/acquired product revenue (up 18% operational; 27% ex‑one‑time items), 35% adjusted operating margin, $6.1B adjusted operating expenses (R&D +12% op, SG&A –3% op), $3.45B operating cash flow and 2.7x leverage. Pfizer reiterated productivity targets — $700M of Phase‑1 manufacturing savings in 2026 (with $175M realized in Q2), remains on track for most of $7.2B in net savings by end‑2026, and expanded programs to target roughly $9.7B of total net savings through 2029 (including ~ $3B from manufacturing optimization).

Pfizer Financial Statement Overview

Summary
Revenue rebounded strongly in the TTM period (+60.2%) with solid profitability (~69% gross margin, ~11.8% net margin), but earnings remain well below the 2021–2022 peak and have been volatile since 2023. Balance sheet leverage is moderate-to-elevated (debt-to-equity ~0.72 TTM) with modest ROE (~8.4% TTM). Cash flow is positive and improving (TTM FCF $11.0B, +15.84%), but debt coverage and cash conversion remain constrained (OCF-to-debt ~0.35; FCF ~79% of net income).
Income Statement
63
Positive
Balance Sheet
66
Positive
Cash Flow
58
Neutral
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue63.70B62.58B63.63B59.55B100.33B81.29B
Gross Profit45.43B44.01B41.85B30.34B62.09B46.88B
EBITDA12.62B15.10B18.13B9.56B41.03B30.79B
Net Income4.33B7.77B8.02B2.13B31.36B22.15B
Balance Sheet
Total Assets201.13B208.16B213.40B226.50B197.21B181.48B
Cash, Cash Equivalents and Short-Term Investments11.70B13.60B20.48B12.69B22.73B31.07B
Total Debt63.19B67.42B66.99B70.84B34.86B37.00B
Total Liabilities115.64B121.39B124.90B137.21B101.29B104.01B
Stockholders Equity85.19B86.48B88.20B89.01B95.66B77.20B
Cash Flow
Free Cash Flow10.99B9.08B9.84B4.79B26.03B29.87B
Operating Cash Flow13.40B11.71B12.74B8.70B29.27B32.58B
Investing Cash Flow-5.68B-1.35B2.65B-32.28B-15.78B-22.55B
Financing Cash Flow-8.40B-10.30B-17.14B26.07B-14.83B-9.82B

Pfizer Technical Analysis

Technical Analysis Sentiment
Positive
Last Price24.54
Price Trends
50DMA
25.11
Positive
100DMA
25.45
Positive
200DMA
25.21
Positive
Market Momentum
MACD
0.82
Negative
RSI
71.75
Negative
STOCH
82.34
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PFE, the sentiment is Positive. The current price of 24.54 is below the 20-day moving average (MA) of 26.30, below the 50-day MA of 25.11, and below the 200-day MA of 25.21, indicating a bullish trend. The MACD of 0.82 indicates Negative momentum. The RSI at 71.75 is Negative, neither overbought nor oversold. The STOCH value of 82.34 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PFE.

Pfizer Risk Analysis

Pfizer disclosed 26 risk factors in its most recent earnings report. Pfizer reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 3 New Risks
1.
We have expended and will continue to expend significant time and resources in connection with the acquisition of Seagen and have incurred substantial indebtedness to fund the acquisition. Q3, 2023
2.
We may not be successful in identifying and executing potential business development transactions, such as our acquisition of Seagen, or realizing the financial and strategic goals that were contemplated at the time of any historical or potential business development transaction, which could have an adverse impact on our ability to meet our growth objectives. Q3, 2023
3.
We may be unable to complete the acquisition of Seagen within the anticipated timeframe or at all, which could prevent us from receiving the anticipated benefits from the acquisition in the anticipated timeframe or at all. Q3, 2023

Pfizer Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
$651.25B31.2425.73%1.99%8.07%-7.21%
75
Outperform
$237.52B27.0989.32%2.61%9.89%31.69%
68
Neutral
$291.05B24.1229.64%3.06%2.33%-4.08%
66
Neutral
$159.99B37.094.89%7.01%-0.21%-59.71%
65
Neutral
$468.22B74.66-136.50%2.63%10.39%68.16%
62
Neutral
$376.37B121.076.60%2.56%4.51%-80.62%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PFE
Pfizer
28.07
4.58
19.49%
AMGN
Amgen
439.33
158.65
56.52%
JNJ
Johnson & Johnson
270.24
95.18
54.37%
MRK
Merck & Company
152.55
70.00
84.80%
NVS
Novartis
158.86
36.22
29.53%
ABBV
AbbVie
264.96
63.66
31.62%

Pfizer Corporate Events

Business Operations and StrategyExecutive/Board ChangesFinancial Disclosures
Pfizer Reaffirms 2026 Outlook Amid CFO Transition
Positive
Jun 18, 2026
Following its June 18, 2026 announcement of a Chief Financial Officer transition, Pfizer reaffirmed the full-year 2026 financial guidance it first issued on December 16, 2025 and reiterated on May 5, 2026. The company continues to project 2026 rev...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 04, 2026