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Merck & Company (MRK)
NYSE:MRK
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Merck & Company (MRK) AI Stock Analysis

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MRK

Merck & Company

(NYSE:MRK)

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Neutral 68 (OpenAI - 5.2)
Rating:68Neutral
Price Target:
$126.00
▲(5.82% Upside)
Action:Reiterated
Date:05/23/26
The score is driven primarily by solid financial performance (high margins and strong free cash flow) and a constructive earnings-call outlook (raised/narrowed non-GAAP guidance and continued KEYTRUDA momentum). Offsetting these positives are earnings/GAAP volatility from large one-time charges and business mix headwinds (e.g., GARDASIL decline), alongside mixed technical signals and less interpretable valuation due to a negative P/E.
Positive Factors
Free Cash Flow Strength
Merck's sustained and growing free cash flow (~$14.1B TTM, +~14%) and FCF at ~79% of net income provide a durable funding base for R&D, acquisitions, dividends and buybacks. Strong cash generation supports strategic optionality and cushions the business through cyclical sales or timing swings.
Negative Factors
Elevated Leverage
Debt-to-equity near ~1.07 TTM indicates meaningful reliance on debt financing. Elevated leverage reduces financial flexibility for large BD or unexpected downturns, increases interest and refinancing risk, and leaves less cushion if profitability or cash conversion weakens over the medium term.
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Positive Factors
Negative Factors
Free Cash Flow Strength
Merck's sustained and growing free cash flow (~$14.1B TTM, +~14%) and FCF at ~79% of net income provide a durable funding base for R&D, acquisitions, dividends and buybacks. Strong cash generation supports strategic optionality and cushions the business through cyclical sales or timing swings.
Read all positive factors

Merck & Company Key Performance Indicators (KPIs)

Any
Any
Operating Expense Breakdown
Operating Expense Breakdown
Details core costs like R&D, marketing, and admin, offering insight into how efficiently the company runs and where it’s prioritizing investment.
Chart InsightsR&D is the clear driver of Merck’s opex, producing lumpy, large-quarter spikes tied to milestone, acquisition and restructuring activity, while SG&A is a steadier, seasonal expense. ‘Restructuring’ and ‘Other’ are noisy and episodic (notable mid‑2022 and 2023 spikes), which masks the underlying run‑rate. Management’s 2026 guidance confirms a one‑time ~$9B Sidera upfront charge that will materially inflate reported operating expenses and depress EPS; strip that out and the company continues heavy R&D investment supporting the pipeline and a path back to normalized margins.
Data provided by:The Fly

Merck & Company (MRK) vs. SPDR S&P 500 ETF (SPY)

Merck & Company Business Overview & Revenue Model

Company Description
Merck & Co., Inc. operates as a healthcare company worldwide. It operates through two segments, Pharmaceutical and Animal Health. The Pharmaceutical segment offers human health pharmaceutical products in the areas of oncology, hospital acute care,...
How the Company Makes Money
Merck primarily makes money by selling branded prescription medicines and vaccines. Revenue is generated when its products are purchased by wholesalers, distributors, hospitals, pharmacies, governments, and other healthcare providers, with demand ...

Merck & Company Earnings Call Summary

Earnings Call Date:Apr 30, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 04, 2026
Earnings Call Sentiment Positive
The call mixed strong commercial and pipeline execution with near-term financial and clinical headwinds. Merck reported solid Q1 revenue growth (+5% YoY; $16.3B), robust KEYTRUDA momentum (+8%, $8.0B), notable product and regulatory milestones (IDVYNSO approval, priority reviews for I-DXd and multiple WELIREG filings), accelerating new-product launches and AI partnerships, and raised/narrowed 2026 guidance. Offsetting these positives were a very large one-time $9B Cidara charge that drove a GAAP loss and distorted tax rate, an expected one-time R&D impact from the proposed Terns deal (~$5.8B), meaningful declines in GARDASIL (-22%), a failed LITESPARK-012 readout, and several near-term reimbursement/seasonality headwinds for specific products (ENFLONSIA, OHTUVAYRE). Overall the company emphasized long-term pipeline value and raised guidance despite near-term charges and select clinical setbacks.
Positive Updates
Quarterly Revenue Growth and Raised Guidance
Total company revenue of $16.3 billion in Q1, up 5% year-over-year (3% ex-FX). Management narrowed and raised 2026 revenue guidance to $65.8B–$67.0B (growth of 1%–3%, including ~1ppt FX) and raised non-GAAP EPS guidance to $5.04–$5.16 (including ~$0.10 FX benefit).
Negative Updates
Large One-Time Cidara Charge and GAAP Loss
Recorded a $9 billion one-time operating charge related to the Cidara acquisition, producing a pretax loss and an effective tax rate of negative 43.5% for the quarter. Reported GAAP loss of $1.28 per share in Q1, which included a negative impact of approximately $3.62 per share from the Cidara charge.
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Q1-2026 Updates
Negative
Quarterly Revenue Growth and Raised Guidance
Total company revenue of $16.3 billion in Q1, up 5% year-over-year (3% ex-FX). Management narrowed and raised 2026 revenue guidance to $65.8B–$67.0B (growth of 1%–3%, including ~1ppt FX) and raised non-GAAP EPS guidance to $5.04–$5.16 (including ~$0.10 FX benefit).
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Company Guidance
Merck narrowed and raised the midpoint of its 2026 non‑GAAP guidance, forecasting revenue of $65.8–$67.0 billion (growth of 1%–3%, including ~1 percentage‑point positive FX impact using mid‑April rates) with a gross margin of ~82%; operating expenses of $36.0–$36.8 billion (range excludes the proposed Terns acquisition and other potential large BD items); other expense of ~$1.3 billion; a full‑year tax rate of 23.5%–24.5% (reflecting the nondeductible Cidara charge); ~2.48 billion shares outstanding; and EPS of $5.04–$5.16 (including an approximate $0.10 FX benefit). Management noted Q1 revenue of $16.3 billion (up 5% year‑over‑year, 3% ex‑FX) and a Q1 loss per share of $1.28 that included a $3.62 per‑share onetime Cidara charge, and warned the Terns deal is expected to add a onetime R&D charge of about $5.8 billion (~$2.35 per share) plus an ~ $0.12 EPS drag in 2026; they remain on pace for roughly $3 billion of share repurchases for the year.

Merck & Company Financial Statement Overview

Summary
Strong underlying profitability (high gross margin and ~28% TTM operating margin) and strong/free-cash-flow generation support financial quality, but earnings have been volatile (sharp 2023 drop, rebound in 2024–2025, with TTM net margin ~14% below peak levels) and leverage is moderate (debt-to-equity ~1.07 TTM).
Income Statement
74
Positive
Balance Sheet
66
Positive
Cash Flow
78
Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue65.59B64.93B64.17B60.12B59.28B48.70B
Gross Profit49.79B46.73B48.98B43.99B41.87B35.08B
EBITDA22.69B29.32B25.71B6.91B21.32B17.90B
Net Income8.94B18.25B17.12B365.00M14.52B13.05B
Balance Sheet
Total Assets128.69B136.87B117.11B106.67B109.16B105.69B
Cash, Cash Equivalents and Short-Term Investments5.70B14.56B13.69B7.09B13.19B8.10B
Total Debt49.12B50.53B38.27B36.27B31.98B34.63B
Total Liabilities82.75B84.20B70.73B69.04B63.10B67.44B
Stockholders Equity45.88B52.61B46.31B37.58B45.99B38.18B
Cash Flow
Free Cash Flow14.12B12.36B18.10B9.14B14.71B9.66B
Operating Cash Flow17.89B16.47B21.47B13.01B19.09B14.11B
Investing Cash Flow-22.46B-13.74B-7.73B-14.08B-4.96B-16.55B
Financing Cash Flow852.00M-1.92B-7.03B-4.81B-9.12B2.59B

Merck & Company Technical Analysis

Technical Analysis Sentiment
Positive
Last Price119.07
Price Trends
50DMA
115.68
Positive
100DMA
114.77
Positive
200DMA
101.32
Positive
Market Momentum
MACD
0.31
Negative
RSI
67.65
Neutral
STOCH
81.81
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MRK, the sentiment is Positive. The current price of 119.07 is above the 20-day moving average (MA) of 112.80, above the 50-day MA of 115.68, and above the 200-day MA of 101.32, indicating a bullish trend. The MACD of 0.31 indicates Negative momentum. The RSI at 67.65 is Neutral, neither overbought nor oversold. The STOCH value of 81.81 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MRK.

Merck & Company Risk Analysis

Merck & Company disclosed 31 risk factors in its most recent earnings report. Merck & Company reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Merck & Company Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$166.82B21.4142.20%2.52%3.83%55.01%
71
Outperform
£215.82B24.4122.41%1.53%4.64%26.75%
69
Neutral
$107.45B15.5514.41%4.58%11.19%-0.23%
68
Neutral
$302.33B17.93%3.12%2.70%-48.28%
67
Neutral
$277.96B23.1031.54%2.87%5.60%9.68%
63
Neutral
$147.62B14.708.37%6.65%1.36%-5.39%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MRK
Merck & Company
122.41
47.55
63.52%
GILD
Gilead Sciences
134.36
29.77
28.46%
NVS
Novartis
152.01
41.43
37.46%
PFE
Pfizer
25.90
4.10
18.83%
SNY
Sanofi
44.29
-5.70
-11.40%
GB:AZN
AstraZeneca
13,916.00
3,658.77
35.67%

Merck & Company Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Merck Completes $6 Billion Multi-Tranche Senior Notes Offering
Positive
May 22, 2026
On May 22, 2026, Merck Co., Inc. completed an underwritten public offering of multiple tranches of senior notes with maturities ranging from 2028 to 2056, including floating rate notes and fixed-rate notes carrying coupons between 4.300% and 5.85...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 23, 2026