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Merck & Company (MRK)
NYSE:MRK
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Merck & Company (MRK) AI Stock Analysis

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MRK

Merck & Company

(NYSE:MRK)

Rating:81Outperform
Price Target:
$96.00
▲(11.52% Upside)
Merck's strong financial performance and attractive valuation are the primary drivers of its stock score. The company's robust profitability and efficient cost management are complemented by a favorable P/E ratio and dividend yield. However, challenges such as declining GARDASIL sales and potential future revenue and asset base declines temper the overall outlook. Technical indicators suggest a neutral trend, while the earnings call highlights both growth opportunities and significant challenges.
Positive Factors
Business Strategy
The newly announced $3bn optimization initiative is viewed as a sensible re-allocation of capital to fund new launches and R&D.
Product Performance
Performance from the company’s key new product cycle, Winrevair, remains intact with optimism on potential label expansion and data from the HYPERION trial.
Negative Factors
Gardasil Franchise
Continued softness and uncertainty around when the Gardasil franchise will find its footing drives investor concerns.
Regulatory Risk
Potential macroeconomic discussions are anticipated regarding new EU tariffs and shifts in Medicare pricing.

Merck & Company (MRK) vs. SPDR S&P 500 ETF (SPY)

Merck & Company Business Overview & Revenue Model

Company DescriptionMerck & Company, known as Merck Sharp & Dohme (MSD) outside the United States and Canada, is a leading global healthcare company dedicated to discovering, developing, and providing innovative medicines, vaccines, and animal health products. Founded in 1891, Merck operates in two primary sectors: Human Health, which includes prescription medicines, vaccines, biologics, and over-the-counter products, and Animal Health, which offers a range of products for livestock and companion animals. The company is renowned for its contributions to medical science, including advancements in oncology, infectious diseases, and vaccines.
How the Company Makes MoneyMerck & Company's revenue model is primarily based on the sales of its pharmaceutical products and vaccines. The Human Health segment generates the majority of its revenue, driven by sales of blockbuster drugs such as Keytruda (for cancer treatment) and Gardasil (a vaccine for HPV). The company also earns revenue from its Animal Health segment, which includes pharmaceuticals, vaccines, and diagnostic products for livestock and pets. Additionally, Merck engages in strategic partnerships and collaborations with other pharmaceutical companies, research institutions, and healthcare organizations, which can provide milestone payments, royalties, and shared revenues. The company further invests in research and development to innovate and expand its product pipeline, which is critical for sustaining long-term growth and profitability.

Merck & Company Key Performance Indicators (KPIs)

Any
Any
Operating Expense Breakdown
Operating Expense Breakdown
Details core costs like R&D, marketing, and admin, offering insight into how efficiently the company runs and where it’s prioritizing investment.
Chart InsightsMerck's operating expenses have shown volatility, particularly in R&D, which spiked in mid-2023, possibly due to strategic investments in new product launches like WINREVAIR. The recent earnings call highlights a multiyear optimization program aimed at redirecting $3 billion from lower-growth areas into high-potential ones, reflecting a strategic shift to bolster growth in oncology and Animal Health. Despite challenges like declining GARDASIL sales in China, Merck's focus on innovation and cost optimization could enhance long-term profitability.
Data provided by:Main Street Data

Merck & Company Earnings Call Summary

Earnings Call Date:Jul 30, 2025
(Q2-2025)
|
% Change Since: 4.18%|
Next Earnings Date:Oct 30, 2025
Earnings Call Sentiment Neutral
The call highlighted Merck's strong performance with new product launches and a robust pipeline, particularly in oncology and cardiopulmonary. However, challenges in China with GARDASIL and competitive pressures from biosimilars were notable lowlights.
Q2-2025 Updates
Positive Updates
WINREVAIR Achieves Significant Milestone
WINREVAIR achieved $1 billion of cumulative sales in just over a year since approval, demonstrating strong market penetration and impact on patients with pulmonary arterial hypertension.
Positive Oncology Pipeline Developments
KEYTRUDA marked its 10th earlier-stage approval, and the company presented encouraging data across multiple novel candidates at ASCO, reinforcing the potential of its oncology portfolio.
Strong Animal Health Growth
Animal Health sales increased by 11%, reflecting higher demand across all species and improved supply.
Successful Launch of ENFLONSIA
ENFLONSIA, a monoclonal antibody for RSV prevention, received FDA approval and ACIP recommendation, showcasing Merck's expansion into new therapeutic areas.
Negative Updates
Decline in GARDASIL Sales
GARDASIL sales decreased by 55%, primarily due to a $1.3 billion decline in China, highlighting challenges in that market.
Revenue Impact from Foreign Exchange
Total company revenues decreased by 2%, affected by foreign exchange impacts and a decline in sales of GARDASIL in China.
Early Biosimilar Entry
An early entrant of a biosimilar for pembrolizumab in Argentina impacted revenues, reflecting competitive pressures in international markets.
Company Guidance
During the Merck & Co., Inc. Q2 2025 conference call, the company reported revenue of $15.8 billion, reflecting a 2% decrease from the previous year, both nominally and excluding foreign exchange impacts. Key growth drivers included oncology and Animal Health, with notable contributions from new products like WINREVAIR, which achieved $1 billion in cumulative sales since its approval. Sales of KEYTRUDA increased by 9% to $8 billion, driven by demand in metastatic and earlier-stage cancers. The company announced a multiyear optimization initiative aiming to reallocate $3 billion from lower-growth areas to support burgeoning growth drivers. They maintained their full-year revenue guidance between $64.3 billion and $65.3 billion, representing 1% to 2% growth, and adjusted their EPS guidance to $8.87 to $8.97. The call highlighted Merck’s strategic focus on expanding its innovative pipeline, with over 80 Phase III studies underway, and confidence in overcoming the upcoming patent expiration of KEYTRUDA.

Merck & Company Financial Statement Overview

Summary
Merck displays strong profitability and cash generation with robust margins and a stable balance sheet. However, recent declines in revenue and asset base suggest potential challenges ahead.
Income Statement
85
Very Positive
Merck & Company has demonstrated consistent revenue growth from $41.52 billion in 2020 to $63.92 billion in TTM (Trailing-Twelve-Months) 2025. The gross profit margin is robust at 81.98% TTM, indicating efficient cost management. Net profit margin is strong at 27.27% TTM, reflecting solid profitability. The EBIT and EBITDA margins at 36.94% and 40.50% TTM, respectively, show a healthy operational performance. However, a slight decline in revenue from 2024 to 2025 suggests potential challenges in sustaining growth.
Balance Sheet
78
Positive
The balance sheet is solid, with a debt-to-equity ratio of 0.72 TTM, indicating a manageable level of leverage. Return on equity (ROE) is impressive at 36.07% TTM, showcasing effective use of shareholder funds. The equity ratio stands at 49.13% TTM, suggesting a stable capital structure. Nonetheless, a decreasing trend in total assets over the recent periods could indicate potential risks in asset management.
Cash Flow
82
Very Positive
Operating cash flow remains strong at $20.88 billion TTM, supporting healthy free cash flow of $17.04 billion. The free cash flow to net income ratio is substantial, highlighting solid cash generation relative to profits. However, a decrease in free cash flow growth rate from 2024 to 2025 may signal future liquidity pressures if not addressed.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue64.17B60.12B59.28B48.70B41.52B
Gross Profit48.98B43.99B41.87B35.08B27.90B
EBITDA25.71B6.91B21.32B17.90B10.18B
Net Income17.12B365.00M14.52B13.05B7.07B
Balance Sheet
Total Assets117.11B106.67B109.16B105.69B91.59B
Cash, Cash Equivalents and Short-Term Investments13.69B7.09B13.19B8.10B8.05B
Total Debt37.11B35.05B30.69B33.10B31.79B
Total Liabilities70.73B69.04B63.10B67.44B66.18B
Stockholders Equity46.31B37.58B45.99B38.18B25.32B
Cash Flow
Free Cash Flow18.10B9.14B14.71B9.66B5.57B
Operating Cash Flow21.47B13.01B19.09B14.11B10.25B
Investing Cash Flow-7.73B-14.08B-4.96B-16.55B-9.44B
Financing Cash Flow-7.03B-4.81B-9.12B2.59B-2.83B

Merck & Company Technical Analysis

Technical Analysis Sentiment
Positive
Last Price86.08
Price Trends
50DMA
81.49
Positive
100DMA
80.14
Positive
200DMA
87.22
Negative
Market Momentum
MACD
0.99
Negative
RSI
65.24
Neutral
STOCH
82.56
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MRK, the sentiment is Positive. The current price of 86.08 is above the 20-day moving average (MA) of 82.08, above the 50-day MA of 81.49, and below the 200-day MA of 87.22, indicating a neutral trend. The MACD of 0.99 indicates Negative momentum. The RSI at 65.24 is Neutral, neither overbought nor oversold. The STOCH value of 82.56 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MRK.

Merck & Company Risk Analysis

Merck & Company disclosed 31 risk factors in its most recent earnings report. Merck & Company reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Merck & Company Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
82
Outperform
$143.96B13.4612.16%6.74%14.72%
81
Outperform
$212.14B13.0935.44%3.78%2.00%20.01%
79
Outperform
$245.82B29.6319.76%1.94%15.08%29.15%
78
Outperform
$238.56B17.9732.82%3.14%12.83%-11.92%
76
Outperform
$122.81B12.488.39%4.38%-9.32%120.62%
67
Neutral
$159.11B24.1899.14%3.12%13.10%110.67%
51
Neutral
$7.77B-0.12-39.78%2.21%22.68%-1.42%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MRK
Merck & Company
86.08
-26.71
-23.68%
AMGN
Amgen
295.76
-24.98
-7.79%
AZN
AstraZeneca
80.46
-4.42
-5.21%
NVS
Novartis
126.82
11.75
10.21%
PFE
Pfizer
25.74
-1.26
-4.67%
SNY
Sanofi
50.61
-3.86
-7.09%

Merck & Company Corporate Events

M&A TransactionsBusiness Operations and StrategyFinancial Disclosures
Merck & Co. Announces New Restructuring Program
Neutral
Jul 29, 2025

On July 25, 2025, Merck & Co. announced a new restructuring program aimed at advancing its pipeline and launching new products, which will involve reducing certain positions and optimizing its manufacturing network. The program is expected to be completed by the end of 2027, with some manufacturing actions extending to 2029, and aims to achieve $3 billion in annual cost savings by reinvesting in strategic growth areas. In the second quarter of 2025, Merck reported a 2% decrease in total worldwide sales to $15.8 billion compared to the same period in 2024, with notable growth in KEYTRUDA sales but a significant decline in GARDASIL sales. The company also announced the acquisition of Verona Pharma and received FDA approval for ENFLONSIA, highlighting its strategic focus on innovation and growth.

The most recent analyst rating on (MRK) stock is a Buy with a $145.00 price target. To see the full list of analyst forecasts on Merck & Company stock, see the MRK Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Merck & Co. Concludes Annual Shareholders Meeting
Neutral
May 29, 2025

On May 27, 2025, Merck & Co., Inc. held its Annual Meeting of Shareholders where several key decisions were made. The meeting resulted in the election of board members, approval of executive compensation, and ratification of the company’s accounting firm for 2025. However, shareholder proposals regarding human rights impact assessment, tax transparency, DEI goals in executive pay, and civil liberties in advertising services were not approved.

The most recent analyst rating on (MRK) stock is a Buy with a $145.00 price target. To see the full list of analyst forecasts on Merck & Company stock, see the MRK Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 14, 2025