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Gilead Sciences (GILD)
NASDAQ:GILD

Gilead Sciences (GILD) AI Stock Analysis

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GILD

Gilead Sciences

(NASDAQ:GILD)

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Outperform 78 (OpenAI - 4o)
Rating:78Outperform
Price Target:
$138.00
▲(14.62% Upside)
Gilead Sciences' strong financial performance and positive earnings call sentiment are the most significant factors driving the stock score. The company's strategic focus on its HIV portfolio and successful product launches contribute positively. Technical indicators suggest some short-term caution, but the long-term outlook remains favorable. The recent patent settlement further enhances Gilead's market position.
Positive Factors
HIV Portfolio Growth
Strong growth in HIV therapies like Biktarvy and Descovy demonstrates Gilead's robust market position in antiviral treatments, ensuring sustained revenue streams.
Patent Protection
Securing patent protection for Biktarvy until 2036 strengthens Gilead's competitive edge, ensuring continued market exclusivity and revenue stability.
Cash Flow Management
Strong cash flow management with high free cash flow growth enhances Gilead's ability to invest in R&D and strategic initiatives, supporting long-term growth.
Negative Factors
Oncology Revenue Decline
Declining oncology revenue indicates competitive pressures and challenges in expanding this segment, potentially impacting future diversification efforts.
Cell Therapy Sales Decline
A decline in cell therapy sales suggests difficulties in maintaining market share, which could hinder Gilead's growth in innovative treatment areas.
Medicare Part D Impact
The Medicare Part D redesign poses a significant financial challenge, potentially affecting Gilead's revenue growth and necessitating strategic adjustments.

Gilead Sciences (GILD) vs. SPDR S&P 500 ETF (SPY)

Gilead Sciences Business Overview & Revenue Model

Company DescriptionGilead Sciences, Inc. is a biopharmaceutical company headquartered in Foster City, California, focused on the discovery, development, and commercialization of innovative medicines in areas of unmet medical need. The company primarily operates in the therapeutic sectors of antiviral, oncology, and inflammation, with a strong emphasis on treatments for HIV/AIDS, liver diseases, and cancer. Gilead's core products include well-known antiviral medications such as Truvada, Biktarvy, and Harvoni, along with a growing portfolio of oncology therapies and other therapeutic agents.
How the Company Makes MoneyGilead Sciences generates revenue primarily through the sale of its pharmaceutical products, particularly those targeting HIV, hepatitis C, and cancer. The company’s key revenue streams include direct sales to healthcare providers and hospitals, as well as partnerships with other pharmaceutical companies for co-marketing and distribution of certain products. Gilead also engages in licensing agreements that allow it to earn royalties on the sales of its drugs by other manufacturers. Significant partnerships, such as collaborations with research institutions and other biotech firms, play a critical role in expanding Gilead’s product pipeline and market reach, ultimately bolstering its earnings. The company maintains a strong focus on research and development, which enables it to introduce new products that can drive future revenue growth.

Gilead Sciences Key Performance Indicators (KPIs)

Any
Any
Revenue by Type
Revenue by Type
Analyzes income from different sources, highlighting which areas are driving growth and which might be underperforming, crucial for assessing the company's financial health and strategic focus.
Chart InsightsGilead Sciences' product revenue shows resilience with a steady upward trend, bolstered by a 2% year-over-year increase, despite a decline in Veklury sales due to reduced COVID-19 hospitalizations. The recent FDA approval of Yeztugo for HIV prevention and strong growth in Biktarvy and Descovy sales highlight strategic advancements in the HIV segment. The company has raised its full-year revenue guidance, reflecting confidence in its robust product pipeline and commercial execution, particularly in HIV and oncology, which are key growth drivers amid challenges in cell therapy and HCV sales.
Data provided by:The Fly

Gilead Sciences Earnings Call Summary

Earnings Call Date:Oct 30, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 10, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant growth in the HIV portfolio and successful launches of new products like Yeztugo, boosting revenue expectations despite challenges in oncology and cell therapy segments. The overall sentiment is positive, driven by strong commercial execution and strategic advancements.
Q3-2025 Updates
Positive Updates
Strong HIV Portfolio Performance
HIV therapies saw impressive growth with Biktarvy up 6% year-over-year, Descovy up 20% year-over-year, and a 35% sequential growth for Livdelzi. Overall, HIV sales increased 4% versus the prior year.
Yeztugo Launch Success
Yeztugo achieved 75% payer coverage nearly 3 months ahead of schedule, contributing $39 million in sales for Q3, indicating a strong start for the new HIV prevention therapy.
Rising Revenue Expectations
Gilead increased its full-year HIV revenue growth expectations to approximately 5% despite a $900 million headwind from the Medicare Part D redesign.
Livdelzi Growth
Livdelzi sales reached over $100 million for the first time, showing a 12% year-over-year growth in the liver portfolio.
Trodelvy Advancements
Trodelvy demonstrated a 38% reduction in disease progression or death in first-line metastatic triple-negative breast cancer patients, with regulatory decisions expected in 2026.
Negative Updates
Decline in Oncology Revenue
Oncology revenue decreased partly due to competitive headwinds and unfavorable inventory dynamics in Trodelvy sales, which were down 2% sequentially.
Cell Therapy Sales Decline
Cell therapy sales were down 11% year-over-year and sequentially, with expectations of a 10% decline for the full year 2025 due to competitive headwinds.
Impact of Medicare Part D Redesign
The HIV business faced a $900 million headwind in 2025 due to the Medicare Part D redesign, impacting overall revenue growth.
Company Guidance
In the third quarter of 2025, Gilead reported robust financial and operational performance, highlighting significant growth across its key therapeutic areas. The company achieved a 6% year-over-year increase in sales for Biktarvy and a 20% rise for Descovy, alongside a notable 35% sequential growth in Livdelzi sales. Non-GAAP EPS grew by 22% year-over-year, driven by disciplined operating expense management, even after accounting for a nonrecurring $0.25 benefit. Gilead's HIV portfolio, including the new Yeztugo for HIV prevention, delivered third-quarter sales of $39 million, with a strong payer coverage of 75% achieved ahead of schedule. Despite a $900 million headwind from Medicare Part D redesign, the company raised its 2025 HIV revenue growth expectations to approximately 5%. Gilead is also progressing its oncology pipeline, aiming for a 2026 commercial launch of Trodelvy in first-line metastatic triple-negative breast cancer. Additionally, the company is preparing for the FDA approval process for bulevirtide in chronic hepatitis delta virus, with a U.S. launch expected in 2026.

Gilead Sciences Financial Statement Overview

Summary
Gilead Sciences presents a strong financial position with robust profitability and improved leverage. The company has shown resilience in revenue growth and effective cash flow management. While past leverage and cash flow volatility pose some risks, the current trajectory indicates solid financial health and operational efficiency.
Income Statement
85
Very Positive
Gilead Sciences shows strong profitability with a high gross profit margin of 78.7% and a net profit margin of 27.9% in TTM. The revenue growth rate has been positive, indicating a recovery from previous declines. EBIT and EBITDA margins are robust, reflecting efficient operations. However, the volatility in EBIT margins over the years suggests some operational challenges.
Balance Sheet
75
Positive
The company has significantly improved its debt-to-equity ratio to 0.13 in TTM, indicating reduced leverage and improved financial stability. Return on equity is strong at 40.7%, showcasing effective use of equity to generate profits. The equity ratio is healthy, but past high leverage levels pose a potential risk if not managed carefully.
Cash Flow
80
Positive
Gilead Sciences demonstrates strong cash flow management with a significant free cash flow growth rate of 161.2% in TTM. The operating cash flow to net income ratio is solid, indicating efficient cash generation relative to net income. The free cash flow to net income ratio is nearly 1, highlighting strong cash conversion. However, past fluctuations in free cash flow growth suggest potential volatility.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue29.09B28.75B27.12B27.28B27.30B24.69B
Gross Profit22.89B22.50B20.62B21.62B20.70B20.12B
EBITDA13.67B4.43B10.50B8.85B11.33B4.13B
Net Income8.11B480.00M5.67B4.59B6.22B123.00M
Balance Sheet
Total Assets58.53B58.99B62.13B63.17B67.95B68.41B
Cash, Cash Equivalents and Short-Term Investments7.35B11.57B7.26B6.38B6.52B7.41B
Total Debt24.94B26.71B24.99B25.23B26.70B31.40B
Total Liabilities37.08B39.75B39.38B41.96B46.89B50.19B
Stockholders Equity21.54B19.33B22.83B21.24B21.07B18.20B
Cash Flow
Free Cash Flow9.16B10.30B7.42B8.34B10.80B7.52B
Operating Cash Flow9.67B10.83B8.01B9.07B11.38B8.17B
Investing Cash Flow-3.18B-3.45B-2.27B-2.47B-3.13B-14.62B
Financing Cash Flow-4.22B-3.43B-5.13B-6.47B-8.88B770.00M

Gilead Sciences Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price120.40
Price Trends
50DMA
121.60
Negative
100DMA
117.72
Positive
200DMA
112.37
Positive
Market Momentum
MACD
-0.21
Positive
RSI
44.55
Neutral
STOCH
37.24
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GILD, the sentiment is Neutral. The current price of 120.4 is below the 20-day moving average (MA) of 124.22, below the 50-day MA of 121.60, and above the 200-day MA of 112.37, indicating a neutral trend. The MACD of -0.21 indicates Positive momentum. The RSI at 44.55 is Neutral, neither overbought nor oversold. The STOCH value of 37.24 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GILD.

Gilead Sciences Risk Analysis

Gilead Sciences disclosed 22 risk factors in its most recent earnings report. Gilead Sciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Gilead Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
80
Outperform
$248.95B13.2739.51%3.27%1.59%58.02%
78
Outperform
$149.38B18.6540.53%2.62%2.76%6407.19%
78
Outperform
$106.69B17.7033.84%4.84%1.26%
77
Outperform
$171.10B24.5681.71%3.00%11.03%65.22%
75
Outperform
$119.28B12.108.39%4.54%-9.32%120.62%
74
Outperform
$146.98B15.0710.59%6.65%4.44%128.96%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GILD
Gilead Sciences
120.40
30.26
33.57%
AMGN
Amgen
317.74
59.64
23.11%
BMY
Bristol-Myers Squibb
52.41
-0.81
-1.52%
MRK
Merck & Company
100.30
3.04
3.13%
PFE
Pfizer
25.85
2.30
9.77%
SNY
Sanofi
48.68
4.21
9.47%

Gilead Sciences Corporate Events

Executive/Board Changes
Gilead Sciences Announces Executive Vice President Departure
Neutral
Nov 19, 2025

On November 19, 2025, Gilead Sciences announced that Deborah H. Telman will step down from her role as Executive Vice President, Corporate Affairs and General Counsel, effective December 5, 2025, with her employment terminating later in the month. This leadership change could impact Gilead’s corporate affairs strategy and legal operations, potentially influencing its industry positioning and stakeholder relations.

Product-Related AnnouncementsLegal Proceedings
Gilead Sciences Settles Patent Litigation on Biktarvy
Positive
Oct 6, 2025

On October 6, 2025, Gilead Sciences announced settlement agreements with Lupin Ltd., Cipla Ltd., and Laurus Labs Ltd. to resolve patent litigations concerning generic versions of Biktarvy®. These agreements prevent the entry of generic Biktarvy tablets in the U.S. market before April 1, 2036, securing Gilead’s market position and patent protection for this product.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 09, 2025