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Regeneron (REGN)
NASDAQ:REGN

Regeneron (REGN) AI Stock Analysis

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REGN

Regeneron

(NASDAQ:REGN)

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Outperform 78 (OpenAI - 4o)
Rating:78Outperform
Price Target:
$898.00
▲(17.66% Upside)
Regeneron's strong financial performance and robust earnings call results are the primary drivers of its high stock score. The company demonstrates solid revenue growth and profitability, supported by a strong balance sheet and cash flow. Technical indicators show bullish momentum, though caution is advised due to overbought signals. Valuation metrics suggest the stock is fairly valued, aligning with its growth potential. Despite some operational challenges, Regeneron's commitment to innovation and strategic investments position it well for future growth.
Positive Factors
Revenue Growth
Dupixent's strong sales growth indicates robust demand and market penetration, supporting Regeneron's revenue expansion and long-term growth prospects.
R&D Pipeline Progress
Advancements in the R&D pipeline demonstrate Regeneron's commitment to innovation and potential for future product launches, enhancing competitive positioning.
Collaboration Agreement
The collaboration with ModeX Therapeutics leverages Regeneron's expertise in multispecific antibodies, potentially expanding its therapeutic offerings and market reach.
Negative Factors
EYLEA Affordability Issues
Affordability challenges for EYLEA could limit its market growth and impact Regeneron's revenue from this key product, necessitating strategic adjustments.
FDA Setback for EYLEA HD
FDA setbacks for EYLEA HD could delay product enhancements and affect sales momentum, impacting Regeneron's competitive edge in the ophthalmology market.
EYLEA U.S. Sales Decline
The decline in EYLEA's U.S. sales suggests potential market saturation or increased competition, which could pressure Regeneron's revenue growth from this segment.

Regeneron (REGN) vs. SPDR S&P 500 ETF (SPY)

Regeneron Business Overview & Revenue Model

Company DescriptionRegeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; and diabetic retinopathy, as well as macular edema following retinal vein occlusion, including macular edema following central retinal vein occlusion and macular edema following branch retinal vein occlusion. It also provides Dupixent injection to treat atopic dermatitis and asthma in adults and pediatrics; Libtayo injection to treat metastatic or locally advanced cutaneous squamous cell carcinoma;Praluent injection for heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in adults; REGEN-COV for covid-19; and Kevzara solution for treating rheumatoid arthritis in adults. In addition, the company offers Inmazeb injection for infection caused by Zaire ebolavirus; ARCALYST injection for cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and muckle-wells syndrome; and ZALTRAP injection for intravenous infusion to treat metastatic colorectal cancer; and develops product candidates for treating patients with eye, allergic and inflammatory, cardiovascular and metabolic, infectious, and rare diseases; and cancer, pain, and hematologic conditions. It has collaboration and license agreements with Sanofi; Bayer; Teva Pharmaceutical Industries Ltd.; Mitsubishi Tanabe Pharma Corporation; Alnylam Pharmaceuticals, Inc.; Roche Pharmaceuticals; and Kiniksa Pharmaceuticals, Ltd., as well as has an agreement with the U.S. Department of Health and Human Services, as well as with Zai Lab Limited; Intellia Therapeutics, Inc.; Biomedical Advanced Research Development Authority; and AstraZeneca PLC. The company was incorporated in 1988 and is headquartered in Tarrytown, New York.
How the Company Makes MoneyRegeneron generates revenue primarily through the sale of its proprietary pharmaceutical products. The company's key revenue streams include sales of EYLEA and Dupixent, which are significant contributors to its overall earnings. Additionally, Regeneron engages in partnerships and collaborations with other pharmaceutical companies and research institutions to develop new therapies, which can also provide financial benefits through milestone payments and royalties. For example, Regeneron has a notable collaboration with Sanofi for the development and commercialization of Dupixent. The company's revenue model is further supported by its robust pipeline of investigational drugs, which, if successfully developed and approved, can lead to additional revenue streams in the future.

Regeneron Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Shows how revenue is distributed across different business units, highlighting which areas are driving growth and which might need strategic adjustments.
Chart InsightsRegeneron's recent revenue trends highlight strong growth in the Collaboration segment, driven by strategic partnerships, while Net Product revenue shows volatility, reflecting challenges with EYLEA sales. The earnings call underscores robust sales growth for Dupixent and Libtayo, offset by EYLEA's decline due to competitive pressures and regulatory delays. The company's strategic pivot to EYLEA HD and a robust R&D pipeline with 45 candidates signal potential future growth, despite current hurdles. Investors should watch for updates on FDA inspections and pivotal data releases in key therapeutic areas.
Data provided by:The Fly

Regeneron Earnings Call Summary

Earnings Call Date:Oct 28, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Jan 30, 2026
Earnings Call Sentiment Neutral
Regeneron demonstrated strong sales growth in key products like Dupixent and Libtayo, along with significant R&D pipeline progress. However, challenges such as affordability issues for EYLEA and FDA-related setbacks tempered some positive outcomes. Overall, the company shows a robust financial position and commitment to innovation, but faces operational hurdles that need addressing.
Q3-2025 Updates
Positive Updates
Dupixent Sales Growth
Worldwide net product sales for Dupixent increased by 26% compared to the third quarter of last year. In the U.S., Dupixent net product sales grew 28%.
Libtayo Sales and FDA Approval
Global Libtayo net product sales were $365 million, up 24% on a constant currency basis. The FDA approved Libtayo for high-risk adjuvant cutaneous squamous cell carcinoma.
EYLEA HD Performance
EYLEA HD in the U.S. grew by 10%, with net product sales reaching $431 million, an all-time high.
R&D Pipeline Progress
Positive Phase III or registration-enabling data for six distinct programs in immunology, neurology, allergy, and rare diseases.
Regeneron's Financial Strength
Generated $3.2 billion in free cash flow through the first 9 months of 2025, with cash and marketable securities less debt of approximately $16 billion.
Negative Updates
EYLEA Affordability Issues
Affordability issues continue to dampen branded anti-VEGF category growth, with EYLEA's match program receiving less than $1 million in donations.
FDA Complete Response Letter for EYLEA HD
FDA issued a complete response letter for the prefilled syringe supplemental BLA due to unresolved inspection findings at Catalent.
EYLEA U.S. Sales Decline
EYLEA's third quarter U.S. net sales decreased 10% quarter-over-quarter, reflecting a commensurate decline in unit demand.
Company Guidance
During the call, Regeneron Pharmaceuticals provided guidance indicating robust growth for several key products. In the third quarter of 2025, Dupixent's global net sales reached $4.9 billion, reflecting a 26% increase over the previous year. Libtayo's sales grew by 24% to $365 million worldwide, with a 12% increase in the U.S., bolstered by its recent FDA approval for high-risk adjuvant cutaneous squamous cell carcinoma. EYLEA HD's U.S. net product sales rose to $431 million, marking a 10% growth. The company anticipates moderate to high single-digit sequential demand growth for EYLEA HD in the fourth quarter. Regeneron also highlighted its intention to invest over $7 billion in manufacturing infrastructure in the U.S. and plans to advance multiple substantial registrational programs in 2026, with a forecasted mid-teens percentage increase in R&D spending.

Regeneron Financial Statement Overview

Summary
Regeneron exhibits strong financial health with impressive revenue growth and profitability metrics. The low leverage and solid equity position enhance financial stability, while healthy cash flows support ongoing operations and potential investments. Despite minor fluctuations in margins and cash flow ratios, the company is well-positioned for sustained growth and resilience in the biotechnology sector.
Income Statement
Regeneron has demonstrated strong revenue growth with a 23.6% increase in the TTM period, indicating robust demand for its products. The company maintains high profitability with a gross profit margin of 85.4% and a net profit margin of 32.1%, showcasing efficient cost management. However, there is a slight decline in EBIT and EBITDA margins compared to previous years, which could indicate rising operational costs or increased competition.
Balance Sheet
The balance sheet is solid with a low debt-to-equity ratio of 0.087, reflecting conservative financial leverage and a strong equity base. Return on equity remains healthy at 15.3%, indicating effective use of shareholder funds. The equity ratio is also strong, suggesting a stable financial position with a significant portion of assets financed by equity.
Cash Flow
Regeneron's cash flow is robust, with a positive free cash flow growth rate of 8.1% in the TTM period. The operating cash flow to net income ratio of 1.15 indicates strong cash generation relative to earnings. However, the free cash flow to net income ratio has slightly decreased, suggesting potential reinvestment needs or increased capital expenditures.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue14.25B14.20B13.12B12.17B16.07B8.50B
Gross Profit12.17B12.23B10.87B10.47B13.35B7.14B
EBITDA5.71B5.32B4.69B5.26B9.67B4.10B
Net Income4.58B4.41B3.95B4.34B8.08B3.51B
Balance Sheet
Total Assets40.17B37.76B33.08B29.21B25.43B17.16B
Cash, Cash Equivalents and Short-Term Investments8.44B9.01B10.84B7.74B5.69B3.59B
Total Debt2.71B2.70B2.70B2.70B2.70B2.70B
Total Liabilities9.21B8.41B7.11B6.55B6.67B6.14B
Stockholders Equity30.96B29.35B25.97B22.66B18.77B11.03B
Cash Flow
Free Cash Flow4.15B3.66B3.67B4.42B6.53B2.00B
Operating Cash Flow5.07B4.42B4.59B5.01B7.08B2.62B
Investing Cash Flow-498.80M-2.47B-3.19B-3.78B-5.38B-70.60M
Financing Cash Flow-4.07B-2.20B-1.79B-1.01B-1.01B-1.97B

Regeneron Technical Analysis

Technical Analysis Sentiment
Positive
Last Price763.23
Price Trends
50DMA
714.49
Positive
100DMA
644.75
Positive
200DMA
603.55
Positive
Market Momentum
MACD
17.45
Positive
RSI
55.99
Neutral
STOCH
49.80
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For REGN, the sentiment is Positive. The current price of 763.23 is above the 20-day moving average (MA) of 754.65, above the 50-day MA of 714.49, and above the 200-day MA of 603.55, indicating a bullish trend. The MACD of 17.45 indicates Positive momentum. The RSI at 55.99 is Neutral, neither overbought nor oversold. The STOCH value of 49.80 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for REGN.

Regeneron Risk Analysis

Regeneron disclosed 47 risk factors in its most recent earnings report. Regeneron reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Regeneron Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
81
Outperform
$19.98B17.0830.39%18.09%3563.21%
79
Outperform
$49.36B37.6224.75%89.58%
78
Outperform
$80.22B18.2715.19%0.45%2.89%0.50%
78
Outperform
$113.87B31.6322.31%10.53%
60
Neutral
$52.56B1,654.8732.73%53.24%
53
Neutral
$23.29B-36.81-2.94%7.04%-25.24%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
REGN
Regeneron
763.23
36.96
5.09%
ALNY
Alnylam Pharma
397.83
161.88
68.61%
INCY
Incyte
101.79
28.60
39.08%
VRTX
Vertex Pharmaceuticals
448.80
40.48
9.91%
ARGX
Argenx Se
800.88
152.26
23.47%
BNTX
BioNTech SE
96.85
-30.03
-23.67%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 26, 2025