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Genmab A/S (GMAB)
NASDAQ:GMAB

Genmab (GMAB) AI Stock Analysis

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Genmab

(NASDAQ:GMAB)

Rating:82Outperform
Price Target:
$26.00
▲(13.74%Upside)
Genmab's overall stock score is driven primarily by its strong financial performance, with a robust balance sheet and effective cash flow management. The technical analysis also supports a positive outlook, although the stock may be nearing overbought levels. Valuation metrics are favorable, though the lack of a dividend yield is a minor drawback.
Positive Factors
Clinical Trials and Data
Rina-S in endometrial cancer shows a promising overall response rate well above standard-of-care treatments, highlighting its potential as a superior therapy.
Company Strategy
Broad activity of Rina-S and development strategy strengthen confidence in success amid growing competition.
Stock Performance
There is increased confidence in the blockbuster potential of Rina-S, with continued clinical success as a key driver to upside in Genmab stock.
Negative Factors
Competitive Landscape
The company provided updates addressing several key questions, including concerns around myelosuppression and positioning within the competitive landscape.
Drug Development Challenges
Management highlighted the challenges of different dose selection due to patient BMI and body surface-area guided dosing.

Genmab (GMAB) vs. SPDR S&P 500 ETF (SPY)

Genmab Business Overview & Revenue Model

Company DescriptionGenmab A/S develops antibody therapeutics for the treatment of cancer and other diseases primarily in Denmark. The company markets DARZALEX, a human monoclonal antibody for the treatment of patients with multiple myeloma (MM); teprotumumab for the treatment of thyroid eye disease; ofatumurnab, a human monoclonal antibody to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis; and Amivantamab for advanced or metastatic gastric or esophageal cancer and NSCLC. Its products include daratumumab to treat MM, non-MM blood cancers, and AL amyloidosis; GEN1047; tisotumab vedotin for treating cervical, ovarian, and solid cancers; DuoBody-PD-L1x4-1BB, and DuoBody-CD40x4-1BB for treating solid tumors; Epcoritamab for relapsed/refractory diffuse large B-cell lymphoma and chronic lymphocytic leukemia; and HexaBody-CD38 and DuoHexaBody-CD37 for treating hematological malignancies. The company's also develops products, which is in Phase 2 comprise Teclistamab for vaso-occlusive crises; Camidanlumab tesirine to treat hodgkin lymphoma and solid tumors; JNJ-64007957 and JNJ-64407564 to treat MM; PRV-015 for treating celiac disease; Mim8 for treating haemophilia A; and Lu AF82422 for treating multiple system atrophy disease. In addition, it has approximately 20 active pre-clinical programs. The company has a commercial license and collaboration agreement with Seagen Inc. to co-develop tisotumab vedotin. It also has a collaboration agreement with CureVac AG for the research and development of differentiated mRNA-based antibody products; AbbVie for the development of epcoritamab; and collaborations with BioNTech, Janssen, Novo Nordisk A/S, BliNK Biomedical SAS, and Bolt Biotherapeutics, Inc. Genmab A/S was founded in 1999 and is headquartered in Copenhagen, Denmark.
How the Company Makes MoneyGenmab generates revenue through a combination of royalties, collaboration agreements, and milestone payments. A significant portion of its revenue comes from royalties on sales of its marketed products, such as DARZALEX, which is commercialized by Janssen Biotech, a subsidiary of Johnson & Johnson. The company also enters into strategic partnerships and licensing agreements with major pharmaceutical companies to co-develop and commercialize its antibody products, which provides upfront payments, development milestones, and sales-based royalties. Additionally, Genmab invests in its own proprietary product pipeline with the potential for future commercialization, thus creating multiple avenues for revenue generation.

Genmab Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q4-2024)
|
% Change Since: 10.97%|
Next Earnings Date:Aug 07, 2025
Earnings Call Sentiment Positive
The earnings call reflects a strong financial performance in 2024 with significant revenue and profit growth, driven by the success of commercialized medicines like EPKINLY and TIVDAK. The company has a robust pipeline with strategic investments and provided optimistic guidance for 2025. However, there are minor concerns about EPKINLY's flat sales in Q4 and the company's dependency on key products amid competitive pressures.
Q4-2024 Updates
Positive Updates
Strong Revenue and Profit Growth
Genmab achieved a 31% total revenue growth in 2024, driven by the success of its commercialized medicines, including EPKINLY and TIVDAK. The company also grew operating profit by 26% and ended the year with nearly $3 billion in cash.
EPKINLY's Market Expansion
EPKINLY received multiple regulatory approvals and achieved $281 million in sales for 2024, driven by strong performance in the U.S. and Japan. The drug is expected to have a peak sales opportunity exceeding $3 billion.
Pipeline and Strategic Investments
Genmab has 12 products in 30 clinical trials, including seven Phase III trials. The company made strategic investments such as the $1.8 billion acquisition of ProfoundBio to accelerate development.
TIVDAK's Continued Growth
TIVDAK achieved $131 million in sales during 2024 and is regarded as the global standard of care in second-line plus recurrent or metastatic cervical cancer.
Robust Financial Guidance for 2025
Genmab provided 2025 guidance with expected revenue growth of 12% at the midpoint and a recurring revenue growth of 18%.
Negative Updates
Flat EPKINLY Sales in Q4
EPKINLY's sales were flat in Q4 compared to Q3, partly due to a one-time accounting adjustment in Europe.
Dependency on Key Products
Genmab's revenue heavily relies on key products like DARZALEX, with potential impacts from emerging competitors like Blenrep.
Company Guidance
On the Genmab Full Year 2024 Financial Results Conference Call held on February 14, 2025, the company reported a robust financial performance, with total revenue growth of 31%, driven by the success of its eight commercialized medicines, including EPKINLY and TIVDAK. Genmab's operating profit grew by 26% despite significant investments, such as the $1.8 billion acquisition of ProfoundBio and a $500 million share buyback. The company ended the year with nearly $3 billion in cash, reinforcing its financial strength. Genmab is advancing its pipeline, with 12 products or product candidates in 30 clinical trials, including seven Phase III trials. The company expects significant revenue growth from its late-stage programs, EPKINLY, Rina-S, and Acasunlimab, by the end of the decade. For 2025, Genmab provided guidance for revenue in the range of $3.3 to $3.7 billion and operating expenses between $2.1 billion and $2.2 billion, projecting 16% growth in operating profit.

Genmab Financial Statement Overview

Summary
Genmab demonstrates robust financial health with strong profitability, a solid balance sheet, and effective cash flow management. Despite a slight recent revenue decline, the company maintains a strong market position with efficient operations and low leverage, providing resilience against market volatility.
Income Statement
85
Very Positive
Genmab exhibits strong profitability with a consistent gross profit margin exceeding 95% across the years. The net profit margin for TTM is a robust 37.1%, highlighting effective cost management. Revenue growth is evident, although there was a decline in the most recent period compared to the previous year, indicating potential market fluctuations or competitive pressures.
Balance Sheet
90
Very Positive
The balance sheet reflects strong financial stability with a low debt-to-equity ratio of 0.027 in TTM, indicating low financial leverage. The equity ratio is high, around 80.4%, showcasing a solid equity base. Return on equity is impressive at 12.7%, reflecting efficient use of equity capital.
Cash Flow
88
Very Positive
Cash flow statements reveal a strong cash generation capability, with a high operating cash flow to net income ratio of 0.97 and a free cash flow to net income ratio of 0.95 in TTM. However, free cash flow growth has seen some fluctuations, indicating potential investment cycles or operational changes.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
22.32B21.53B16.47B14.60B8.48B10.11B
Gross Profit
21.23B20.54B16.25B14.60B8.48B10.11B
EBIT
6.27B6.70B5.32B6.27B2.95B6.31B
EBITDA
6.62B9.70B5.56B7.35B3.15B6.54B
Net Income Common Stockholders
6.71B7.84B4.35B5.45B2.96B4.76B
Balance SheetCash, Cash Equivalents and Short-Term Investments
3.23B21.10B28.14B22.32B19.34B16.08B
Total Assets
6.59B45.81B35.29B30.28B24.63B21.14B
Total Debt
143.00M1.03B770.00M597.00M425.00M319.00M
Net Debt
-1.48B-8.83B-14.10B-9.30B-8.53B-6.94B
Total Liabilities
1.29B9.11B3.68B2.84B2.43B2.02B
Stockholders Equity
5.30B36.70B31.61B27.44B22.20B19.12B
Cash FlowFree Cash Flow
6.35B7.58B7.00B3.60B1.98B6.13B
Operating Cash Flow
6.54B7.77B7.38B3.91B2.23B6.43B
Investing Cash Flow
-8.51B-9.91B-1.28B-2.76B-961.00M-2.35B
Financing Cash Flow
-3.34B-3.92B-606.00M-789.00M-420.00M71.00M

Genmab Technical Analysis

Technical Analysis Sentiment
Positive
Last Price22.86
Price Trends
50DMA
20.55
Positive
100DMA
20.64
Positive
200DMA
21.77
Positive
Market Momentum
MACD
0.68
Negative
RSI
65.52
Neutral
STOCH
88.25
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GMAB, the sentiment is Positive. The current price of 22.86 is above the 20-day moving average (MA) of 21.65, above the 50-day MA of 20.55, and above the 200-day MA of 21.77, indicating a bullish trend. The MACD of 0.68 indicates Negative momentum. The RSI at 65.52 is Neutral, neither overbought nor oversold. The STOCH value of 88.25 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GMAB.

Genmab Risk Analysis

Genmab disclosed 51 risk factors in its most recent earnings report. Genmab reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Genmab Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
84
Outperform
$11.39B18.9430.22%24.49%244.87%
82
Outperform
$14.04B12.8322.69%25.11%46.46%
76
Outperform
$12.78B11.3119.94%19.85%21.16%
74
Outperform
$13.79B220.360.47%17.13%-88.78%
71
Outperform
$10.79B20.879.64%17.99%152.10%
54
Neutral
$5.34B3.27-45.10%3.30%16.80%0.02%
52
Neutral
$10.31B357.68%10.69%34.71%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GMAB
Genmab
22.86
-2.94
-11.40%
BMRN
BioMarin Pharmaceutical
56.24
-27.91
-33.17%
EXEL
Exelixis
41.75
20.19
93.65%
INCY
Incyte
71.22
9.78
15.92%
UTHR
United Therapeutics
288.56
-17.48
-5.71%
ASND
Ascendis Pharma
177.71
54.52
44.26%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.