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Genmab A/S (GMAB)
NASDAQ:GMAB
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Genmab (GMAB) AI Stock Analysis

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GMAB

Genmab

(NASDAQ:GMAB)

Rating:82Outperform
Price Target:
$28.00
▲(13.59% Upside)
Genmab's overall stock score is driven by strong earnings call results and positive technical indicators, highlighting robust growth prospects and market momentum. The company's solid financial performance, despite recent revenue and cash flow challenges, supports its stability. Valuation metrics suggest the stock is undervalued, offering potential upside. The absence of significant corporate events does not impact the score.
Positive Factors
Financial performance
Genmab recorded a diluted net income of $5.42 per share, which exceeded the previously forecasted $4.13 per share.
Pipeline development
Management provided insights on the future development strategy for both programs, which collectively informed their confidence in achieving long-term revenue growth for the company.
Negative Factors
Competitive landscape
Data to date in NSCLC for acasunlimab has been lackluster in a highly competitive space.
Patent concerns
The outlook remains guarded given uncertainty as to whether Genmab can overcome the Darzalex patent cliff by 2030.

Genmab (GMAB) vs. SPDR S&P 500 ETF (SPY)

Genmab Business Overview & Revenue Model

Company DescriptionGenmab A/S develops antibody therapeutics for the treatment of cancer and other diseases primarily in Denmark. The company markets DARZALEX, a human monoclonal antibody for the treatment of patients with multiple myeloma (MM); teprotumumab for the treatment of thyroid eye disease; ofatumurnab, a human monoclonal antibody to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis; and Amivantamab for advanced or metastatic gastric or esophageal cancer and NSCLC. Its products include daratumumab to treat MM, non-MM blood cancers, and AL amyloidosis; GEN1047; tisotumab vedotin for treating cervical, ovarian, and solid cancers; DuoBody-PD-L1x4-1BB, and DuoBody-CD40x4-1BB for treating solid tumors; Epcoritamab for relapsed/refractory diffuse large B-cell lymphoma and chronic lymphocytic leukemia; and HexaBody-CD38 and DuoHexaBody-CD37 for treating hematological malignancies. The company's also develops products, which is in Phase 2 comprise Teclistamab for vaso-occlusive crises; Camidanlumab tesirine to treat hodgkin lymphoma and solid tumors; JNJ-64007957 and JNJ-64407564 to treat MM; PRV-015 for treating celiac disease; Mim8 for treating haemophilia A; and Lu AF82422 for treating multiple system atrophy disease. In addition, it has approximately 20 active pre-clinical programs. The company has a commercial license and collaboration agreement with Seagen Inc. to co-develop tisotumab vedotin. It also has a collaboration agreement with CureVac AG for the research and development of differentiated mRNA-based antibody products; AbbVie for the development of epcoritamab; and collaborations with BioNTech, Janssen, Novo Nordisk A/S, BliNK Biomedical SAS, and Bolt Biotherapeutics, Inc. Genmab A/S was founded in 1999 and is headquartered in Copenhagen, Denmark.
How the Company Makes MoneyGenmab primarily generates revenue through a combination of product sales, royalties, and collaboration agreements. The company's flagship product, Darzalex, has become a significant source of income since its approval, generating substantial sales revenue as it is used in various cancer treatments. In addition to product sales, Genmab earns royalties from the commercialization of its products by partners, particularly in the case of Darzalex, which is marketed by Janssen Biotech. Furthermore, Genmab engages in strategic partnerships and licensing agreements with other pharmaceutical companies, which provide upfront payments, milestone payments based on clinical development progress, and additional royalties on future sales. These collaborative efforts enhance its revenue streams and foster innovation while mitigating development risks.

Genmab Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: 14.60%|
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Positive
The earnings call reflects a strong financial performance and promising clinical trial results, particularly for EPKINLY and Rina-S. The company is strategically investing in its pipeline and expanding its market presence. However, challenges such as the discontinuation of HexaBody-OX40 and potential regulatory hurdles were noted.
Q2-2025 Updates
Positive Updates
Strong Financial Performance
Total revenue grew by 19%, with operating profit increasing by 56%. Recurring revenue also rose by 27%, driven by strong product sales from EPKINLY and Tivdak.
Positive Phase III EPCORE-FL1 Trial Results
The EPCORE-FL1 trial met its dual primary endpoints, reducing the risk of disease progression or death by 79%. This supports global regulatory submissions and highlights the potential to transform treatment paradigms.
Continued Commercial Success
EPKINLY and Tivdak sales grew by 60% year-over-year, contributing 31% of total revenue growth. EPKINLY posted a 74% increase in global sales.
Expanded Pipeline and Strategic Investments
The company is investing in high-impact programs with plans for additional Phase III trials for Rina-S and evaluating acasunlimab in advanced melanoma.
Improved 2025 Financial Guidance
Revenue guidance increased to $3.5 billion to $3.7 billion, reflecting a robust 15% growth at the midpoint.
Negative Updates
Discontinuation of HexaBody-OX40
The HexaBody-OX40 program was discontinued due to lack of differentiation and prioritization of other opportunities.
Regulatory Environment Concerns
Concerns were raised about potential regulatory pushback from the FDA on certain submissions, though the company expressed confidence in navigating these challenges.
Company Guidance
During the Genmab First Half 2025 Financial Results Conference Call, key guidance metrics included a 19% growth in total revenue, a 56% increase in operating profit, and an end-of-period cash reserve of around $3 billion. The company completed a share buyback in June, indicating confidence in its future. Notably, Genmab's late-stage pipeline is progressing, with the FDA granting priority review to their sBLA for epcoritamab in second-line follicular lymphoma, which could make it the first bispecific antibody combination available for this indication. The EPCORE FL-1 study showed a 79% reduction in disease progression or death risk. EPKINLY sales reached $211 million, a 74% increase year-over-year, contributing to a 31% share of total revenue growth alongside Tivdak. Genmab also raised its 2025 revenue guidance to $3.5 to $3.7 billion, reflecting a 15% growth at the midpoint, with recurring revenues anticipated to grow by 22%.

Genmab Financial Statement Overview

Summary
Genmab demonstrates robust financial health with strong profitability, a solid balance sheet, and effective cash flow management. Despite a slight recent revenue decline, the company maintains a strong market position with efficient operations and low leverage, providing resilience against market volatility.
Income Statement
85
Very Positive
Genmab exhibits strong profitability with a consistent gross profit margin exceeding 95% across the years. The net profit margin for TTM is a robust 37.1%, highlighting effective cost management. Revenue growth is evident, although there was a decline in the most recent period compared to the previous year, indicating potential market fluctuations or competitive pressures.
Balance Sheet
90
Very Positive
The balance sheet reflects strong financial stability with a low debt-to-equity ratio of 0.027 in TTM, indicating low financial leverage. The equity ratio is high, around 80.4%, showcasing a solid equity base. Return on equity is impressive at 12.7%, reflecting efficient use of equity capital.
Cash Flow
88
Very Positive
Cash flow statements reveal a strong cash generation capability, with a high operating cash flow to net income ratio of 0.97 and a free cash flow to net income ratio of 0.95 in TTM. However, free cash flow growth has seen some fluctuations, indicating potential investment cycles or operational changes.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue17.84B21.53B16.47B14.60B8.48B10.11B
Gross Profit16.88B20.54B16.25B14.60B8.48B10.11B
EBITDA5.27B9.70B5.56B7.35B3.15B6.54B
Net Income5.64B7.84B4.35B5.45B2.96B4.76B
Balance Sheet
Total Assets6.46B45.81B35.29B30.28B24.63B21.14B
Cash, Cash Equivalents and Short-Term Investments2.90B21.10B28.14B22.32B19.34B16.08B
Total Debt148.00M1.03B770.00M597.00M425.00M319.00M
Total Liabilities1.16B9.11B3.68B2.84B2.43B2.02B
Stockholders Equity5.30B36.70B31.61B27.44B22.20B19.12B
Cash Flow
Free Cash Flow4.91B7.58B7.00B3.60B1.98B6.13B
Operating Cash Flow5.09B7.77B7.38B3.91B2.23B6.43B
Investing Cash Flow289.00M-9.91B-1.28B-2.76B-961.00M-2.35B
Financing Cash Flow-692.00M-3.92B-606.00M-789.00M-420.00M71.00M

Genmab Technical Analysis

Technical Analysis Sentiment
Positive
Last Price24.65
Price Trends
50DMA
22.01
Positive
100DMA
21.16
Positive
200DMA
21.12
Positive
Market Momentum
MACD
0.63
Negative
RSI
67.82
Neutral
STOCH
94.44
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GMAB, the sentiment is Positive. The current price of 24.65 is above the 20-day moving average (MA) of 22.67, above the 50-day MA of 22.01, and above the 200-day MA of 21.12, indicating a bullish trend. The MACD of 0.63 indicates Negative momentum. The RSI at 67.82 is Neutral, neither overbought nor oversold. The STOCH value of 94.44 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GMAB.

Genmab Risk Analysis

Genmab disclosed 51 risk factors in its most recent earnings report. Genmab reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Genmab Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
82
Outperform
$14.54B11.9226.08%23.25%64.46%
80
Outperform
$16.69B19.6024.30%18.87%1088.27%
78
Outperform
$14.17B11.9719.30%17.62%19.89%
78
Outperform
$11.00B17.1711.62%17.38%153.58%
73
Outperform
$10.10B18.1629.00%10.73%81.66%
61
Neutral
$11.79B357.68%55.77%46.81%
51
Neutral
$7.82B-0.16-39.78%2.19%21.38%-1.56%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GMAB
Genmab
24.65
-2.71
-9.90%
BMRN
BioMarin Pharmaceutical
58.58
-31.40
-34.90%
EXEL
Exelixis
38.63
12.90
50.14%
INCY
Incyte
85.04
19.88
30.51%
UTHR
United Therapeutics
312.23
-34.44
-9.93%
ASND
Ascendis Pharma
194.30
55.77
40.26%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 20, 2025