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Genmab A/S (GMAB)
NASDAQ:GMAB

Genmab (GMAB) AI Stock Analysis

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GMAB

Genmab

(NASDAQ:GMAB)

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Outperform 76 (OpenAI - 5.2)
Rating:76Outperform
Price Target:
$38.00
▲(19.12% Upside)
Genmab's strong financial performance and positive earnings call sentiment are the primary drivers of its score. The company's strategic initiatives and solid valuation further support its potential, despite some technical indicators suggesting caution.
Positive Factors
Strong balance sheet and liquidity
Extremely low leverage and a high equity ratio provide durable financial flexibility. Combined with roughly $3.4B cash noted on the earnings call, the company can fund late-stage trials, M&A and commercialization investments without immediate outside financing over the next 2-6 months.
High margins and robust profitability
Very strong gross and operating margins indicate durable economics from royalties and product sales. High profitability and ROE (~24.7%) support reinvestment into R&D and commercialization, insulating operating cash generation versus revenue swings over the medium term.
Strategic M&A strengthens late‑stage pipeline
Completing the Merus acquisition is a structural boost: it adds a late‑stage asset with breakthrough designations and is projected to be accretive long‑term. This diversifies the clinical portfolio and accelerates Genmab’s shift toward a broader oncology commercial footprint.
Negative Factors
Declining revenue and free cash flow growth
Material deceleration in reported revenue growth and a notable drop in free cash flow growth reduce internal funding capacity for expensive late‑stage programs. Over 2-6 months this can force tougher prioritization, slower program progress or increased reliance on external financing.
Concentration risk from partner royalties
Large reliance on DARZALEX royalties creates durable revenue concentration and exposure to partner commercial execution, pricing, or competitive threats. Adverse developments at the product or partner level could materially affect Genmab’s revenue base and cash generation over the medium term.
Increased leverage and potential dilution to fund M&A
Significant debt issuance and large term loans for the acquisition increase interest burden and financial leverage, reducing flexibility. Coupled with Articles changes allowing warrants/convertibles, this raises medium‑term dilution and higher fixed costs that could constrain strategic optionality.

Genmab (GMAB) vs. SPDR S&P 500 ETF (SPY)

Genmab Business Overview & Revenue Model

Company DescriptionGenmab A/S develops antibody therapeutics for the treatment of cancer and other diseases primarily in Denmark. The company markets DARZALEX, a human monoclonal antibody for the treatment of patients with multiple myeloma (MM); teprotumumab for the treatment of thyroid eye disease; ofatumurnab, a human monoclonal antibody to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis; and Amivantamab for advanced or metastatic gastric or esophageal cancer and NSCLC. Its products include daratumumab to treat MM, non-MM blood cancers, and AL amyloidosis; GEN1047; tisotumab vedotin for treating cervical, ovarian, and solid cancers; DuoBody-PD-L1x4-1BB, and DuoBody-CD40x4-1BB for treating solid tumors; Epcoritamab for relapsed/refractory diffuse large B-cell lymphoma and chronic lymphocytic leukemia; and HexaBody-CD38 and DuoHexaBody-CD37 for treating hematological malignancies. The company's also develops products, which is in Phase 2 comprise Teclistamab for vaso-occlusive crises; Camidanlumab tesirine to treat hodgkin lymphoma and solid tumors; JNJ-64007957 and JNJ-64407564 to treat MM; PRV-015 for treating celiac disease; Mim8 for treating haemophilia A; and Lu AF82422 for treating multiple system atrophy disease. In addition, it has approximately 20 active pre-clinical programs. The company has a commercial license and collaboration agreement with Seagen Inc. to co-develop tisotumab vedotin. It also has a collaboration agreement with CureVac AG for the research and development of differentiated mRNA-based antibody products; AbbVie for the development of epcoritamab; and collaborations with BioNTech, Janssen, Novo Nordisk A/S, BliNK Biomedical SAS, and Bolt Biotherapeutics, Inc. Genmab A/S was founded in 1999 and is headquartered in Copenhagen, Denmark.
How the Company Makes MoneyGenmab generates revenue primarily through collaborations and partnerships with major pharmaceutical companies, where it receives upfront payments, milestone payments based on the progress of drug development, and royalties on sales of commercialized products. The company has significant collaborations with firms such as Johnson & Johnson and AbbVie, which contribute to its earnings through shared development costs and revenue from successful products. Additionally, Genmab also earns revenue from the sale of its own proprietary products, such as Darzalex (daratumumab), which is marketed for multiple myeloma, contributing to a steady stream of income from sales. These diverse revenue streams, including both collaboration agreements and product sales, form the backbone of Genmab's financial model.

Genmab Earnings Call Summary

Earnings Call Date:Nov 10, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:May 07, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth, a solid financial position, and strategic advancements with the proposed acquisition of Merus. However, there were some challenges, including the termination of GEN1042 development in head and neck cancer and a sales miss for EPKINLY. Overall, the positives of strong financial performance and strategic growth initiatives outweigh the negatives.
Q3-2025 Updates
Positive Updates
Significant Revenue Growth
Total revenue grew by 21%, with operating profit increasing by 52%. EPKINLY and TIVDAK sales rose by 54% year-over-year, contributing to 25% of total revenue growth.
Strong Financial Position
Genmab ended the first half with around $3.4 billion in cash, providing a solid financial foundation for continued growth.
Proposed Acquisition of Merus
The acquisition is expected to advance Genmab's evolution into a global biotech leader, adding high potential assets like petosemtamab to the portfolio.
EPKINLY's Market Performance
EPKINLY posted $333 million through Q3, a 64% year-over-year increase, reinforcing its position as a leader in the third-line setting for diffuse large B-cell lymphoma and follicular lymphoma.
Advancements in Rina-S Development
Rina-S showed deep and durable responses in endometrial cancer. The program is progressing with three ongoing Phase III trials.
Negative Updates
Challenges with GEN1042 Development
Data in frontline head and neck cancer did not meet the high bar for continued development, leading to termination of this line of research.
Miss in EPKINLY Sales Expectations
There was a miss in EPKINLY sales performance this quarter, though future growth is anticipated as it moves into earlier lines of therapy.
Company Guidance
During the Genmab financial results call for the first nine months of 2025, the company reported a 21% increase in total revenue, driven by a growth in recurring revenue, and an impressive 52% growth in operating profit. Genmab ended the first half with around $3.4 billion in cash, supporting its strategy of investing in high-impact late-stage programs. Key developments included rapid progress for EPKINLY and Rina-S, with additional Phase III trials initiated for Rina-S. The proposed acquisition of Merus is seen as transformative, potentially adding petosemtamab to the portfolio, which has received two breakthrough therapy designations. Genmab's guidance for 2025 projects revenue between $3.5 billion and $3.7 billion, with an anticipated 15% growth and operating profit expected between $1.1 billion and $1.4 billion, highlighting disciplined investment and operational efficiency.

Genmab Financial Statement Overview

Summary
Genmab shows strong profitability with high margins and a solid balance sheet with low leverage. However, the decline in revenue and free cash flow growth poses potential risks.
Income Statement
75
Positive
Genmab's income statement shows strong profitability with a high gross profit margin of 94.46% and a net profit margin of 37.38% for TTM. However, the revenue growth rate has declined by 24.35% in the TTM period, indicating a potential challenge in maintaining growth momentum. The EBIT and EBITDA margins remain robust at 36.81% and 38.60% respectively, showcasing operational efficiency.
Balance Sheet
85
Very Positive
The balance sheet reflects a solid financial position with a low debt-to-equity ratio of 0.028, indicating minimal leverage. The return on equity is strong at 24.67%, suggesting effective use of equity capital. The equity ratio stands at 81.92%, highlighting a stable capital structure with a significant portion of assets funded by equity.
Cash Flow
70
Positive
Cash flow analysis reveals a decline in free cash flow growth by 21.73% in the TTM period, which could be a concern for future liquidity. However, the operating cash flow to net income ratio is healthy at 1.77, and the free cash flow to net income ratio is strong at 0.94, indicating efficient cash generation relative to net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue14.04B21.53B16.47B14.51B8.42B10.11B
Gross Profit13.24B20.54B16.25B14.51B8.42B10.11B
EBITDA5.96B9.70B5.95B7.35B4.18B6.16B
Net Income6.57B7.84B4.35B5.45B2.96B4.76B
Balance Sheet
Total Assets7.02B45.81B35.29B30.12B24.63B21.14B
Cash, Cash Equivalents and Short-Term Investments3.41B21.10B28.14B22.32B19.34B16.08B
Total Debt142.00M1.03B770.00M597.00M425.00M319.00M
Total Liabilities1.27B9.11B3.68B2.84B2.43B2.02B
Stockholders Equity5.75B36.70B31.61B27.28B22.20B19.12B
Cash Flow
Free Cash Flow2.91B7.58B7.00B3.60B1.98B6.13B
Operating Cash Flow3.21B7.77B7.38B3.91B2.23B6.43B
Investing Cash Flow-67.42M-9.91B-1.28B-2.76B-961.00M-2.35B
Financing Cash Flow-2.64B-3.92B-606.00M-789.00M-420.00M71.00M

Genmab Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price31.90
Price Trends
50DMA
32.49
Negative
100DMA
31.32
Positive
200DMA
26.73
Positive
Market Momentum
MACD
0.08
Positive
RSI
44.87
Neutral
STOCH
33.39
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GMAB, the sentiment is Neutral. The current price of 31.9 is below the 20-day moving average (MA) of 33.36, below the 50-day MA of 32.49, and above the 200-day MA of 26.73, indicating a neutral trend. The MACD of 0.08 indicates Positive momentum. The RSI at 44.87 is Neutral, neither overbought nor oversold. The STOCH value of 33.39 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GMAB.

Genmab Risk Analysis

Genmab disclosed 51 risk factors in its most recent earnings report. Genmab reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Genmab Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
81
Outperform
$20.14B17.2130.39%18.09%3563.21%
80
Outperform
$25.22B24.5711.51%2.23%3.72%-31.46%
76
Outperform
$19.53B13.4428.20%24.98%127.06%
71
Outperform
$11.07B21.599.07%12.31%60.21%
53
Neutral
$26.15B-41.37-2.94%7.04%-25.24%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$13.43B-51.74103.32%47.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GMAB
Genmab
31.90
12.43
63.84%
BMRN
BioMarin Pharmaceutical
57.62
-6.57
-10.23%
INCY
Incyte
102.60
27.34
36.33%
ASND
Ascendis Pharma
219.73
90.32
69.79%
BNTX
BioNTech SE
108.77
-13.61
-11.12%
RPRX
Royalty Pharma
43.68
13.00
42.37%

Genmab Corporate Events

Genmab Reports 2025 DARZALEX Net Sales of USD 14.4 Billion
Jan 21, 2026

On January 21, 2026, Genmab reported that 2025 worldwide net trade sales of the multiple myeloma therapy DARZALEX (daratumumab), including its subcutaneous formulation DARZALEX FASPRO, reached USD 14.351 billion, according to figures from license partner Johnson & Johnson’s Janssen unit. Sales totaled USD 8.266 billion in the United States and USD 6.085 billion in the rest of the world, and Genmab earns royalties on all global DARZALEX sales under its exclusive worldwide license agreement with J&J, underscoring the product’s continued commercial strength and its importance as a major revenue driver for the Danish biotech.

The most recent analyst rating on (GMAB) stock is a Buy with a $39.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Reports Positive Phase 3 Progression-Free Survival Data for Epcoritamab in Relapsed/Refractory DLBCL
Jan 16, 2026

On January 16, 2026, Genmab reported topline Phase 3 results from its global EPCORE DLBCL-1 trial of subcutaneous bispecific antibody epcoritamab in patients with relapsed or refractory diffuse large B‑cell lymphoma who were ineligible for high‑dose chemotherapy and autologous stem cell transplant. The study, which enrolled 483 patients and compared epcoritamab monotherapy with standard chemo‑immunotherapy regimens R‑GemOx or BR, showed a statistically significant improvement in progression‑free survival and gains in complete response rate, duration of response and time to next treatment, while overall survival did not reach statistical significance and safety findings appeared consistent with the known profile. Genmab and partner AbbVie plan to discuss the data with global regulators and continue to position epcoritamab as a potential core therapy across B‑cell malignancies, supported by multiple ongoing Phase 3 programs in both frontline and relapsed DLBCL and follicular lymphoma that could further expand its clinical and commercial footprint if successful.

The most recent analyst rating on (GMAB) stock is a Buy with a $38.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Drops Acasunlimab to Refocus Investment on Late-Stage Cancer Pipeline
Dec 29, 2025

On December 29, 2025, Genmab announced it would discontinue further clinical development of acasunlimab following a portfolio review and assessment of a more competitive market landscape. Although the company described the drug’s clinical profile to date as encouraging, management said it will redirect resources toward late-stage programs it sees as having higher potential impact, notably EPKINLY (epcoritamab), petosemtamab and rinatabart sesutecan (Rina-S). The move underscores Genmab’s disciplined approach to portfolio prioritization and capital allocation, and the company emphasized that the decision will not affect its full-year 2025 financial guidance, reassuring investors that its broader pipeline momentum and financial outlook remain intact.

The most recent analyst rating on (GMAB) stock is a Hold with a $26.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Completes Acquisition of Merus N.V. to Bolster Oncology Portfolio
Dec 12, 2025

On December 12, 2025, Genmab A/S announced the successful completion of its tender offer to acquire all outstanding common shares of Merus N.V. for $97 per share, marking a significant step in its strategy to become a global biotechnology leader. This acquisition adds petosemtamab, a late-stage asset with two Breakthrough Therapy Designations, to Genmab’s portfolio, and is expected to be accretive to the company’s EBITDA by the end of 2029, with potential multi-billion-dollar annual revenue thereafter.

The most recent analyst rating on (GMAB) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab A/S Discloses Managerial Share Transactions as of December 1, 2025
Dec 1, 2025

On December 1, 2025, Genmab A/S announced transactions involving shares and linked securities conducted by its managerial employees and their closely associated persons. These transactions, which were acquisitions due to the vesting of restricted stock units, reflect internal movements within the company’s stock holdings. The disclosure is in compliance with market regulations and highlights the vested interests of key personnel in Genmab’s operational success.

The most recent analyst rating on (GMAB) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab A/S Updates Articles of Association for Financial Flexibility
Nov 26, 2025

On November 26, 2025, Genmab A/S announced updates to its Articles of Association, which include authorizations for the Board of Directors to increase the company’s share capital and issue warrants and convertible debt instruments. These changes are aimed at providing financial flexibility and supporting the company’s growth strategy, potentially impacting shareholder value and market positioning.

The most recent analyst rating on (GMAB) stock is a Buy with a $45.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Grants Stock Units and Warrants to Employees
Nov 20, 2025

On November 20, 2025, Genmab A/S announced the grant of 6,933 restricted stock units and 7,377 warrants to its employees and subsidiaries. These grants are part of Genmab’s compensation strategy to incentivize and retain talent, with the restricted stock units and warrants vesting over a period of three years. This move underscores Genmab’s commitment to aligning employee interests with company growth and enhancing its competitive positioning in the biotechnology industry.

The most recent analyst rating on (GMAB) stock is a Buy with a $41.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab A/S Discloses Managerial Share Transactions
Nov 19, 2025

On November 19, 2025, Genmab A/S announced transactions involving shares and linked securities conducted by its managerial employees and their closely associated persons. These transactions, disclosed in accordance with market abuse regulations, involved the sale of 175 shares at an average price of DKK 1,960.35 across multiple exchanges. This announcement reflects the company’s transparency in financial dealings, potentially impacting stakeholder trust and market perception.

The most recent analyst rating on (GMAB) stock is a Buy with a $41.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab A/S Updates Articles of Association to Enhance Capital Flexibility
Nov 19, 2025

Genmab A/S has updated its Articles of Association, authorizing the Board of Directors to increase the company’s share capital and issue warrants and convertible debt instruments. These changes, effective until 2029, aim to provide flexibility in capital management and potentially enhance shareholder value.

The most recent analyst rating on (GMAB) stock is a Buy with a $41.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Announces Capital Increase Following Employee Warrant Exercise
Nov 18, 2025

On November 18, 2025, Genmab A/S announced a capital increase of 32,059 shares following the exercise of employee warrants, generating approximately DKK 43.2 million. This increase, which represents about 0.05% of the company’s share capital, will be listed on Nasdaq Copenhagen and is expected to be finalized shortly. The new shares are ordinary, freely transferable, and come with rights to dividends. This move reflects Genmab’s ongoing efforts to enhance its financial position and support its strategic goals in the biotechnology sector.

The most recent analyst rating on (GMAB) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab’s EPKINLY® Combination Therapy Gains FDA Approval for Follicular Lymphoma
Nov 18, 2025

On November 18, 2025, Genmab A/S announced that the U.S. FDA approved EPKINLY® (epcoritamab-bysp) in combination with rituximab and lenalidomide for treating relapsed or refractory follicular lymphoma. This approval is significant as it marks the first FDA approval for a bispecific combination therapy in the lymphoma space, potentially setting a new standard of care. The approval was based on the Phase 3 EPCORE® FL-1 trial, which demonstrated superior progression-free survival and overall response rates compared to standard treatments. The approval could enhance Genmab’s positioning in the oncology market and provide new treatment options for patients with follicular lymphoma.

The most recent analyst rating on (GMAB) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Announces $2.5 Billion Note Offering for Merus Acquisition
Nov 12, 2025

On November 10, 2025, Genmab A/S announced a proposed private offering of $1.5 billion in senior secured notes due 2032 and $1.0 billion in senior unsecured notes due 2033, alongside the syndication of a new $2.0 billion senior secured term loan facility. The funds raised will be used to finance the acquisition of Merus N.V., a strategic move expected to enhance Genmab’s market position in the biotechnology sector. The offering is part of a broader financing strategy that includes previously syndicated credit facilities, and it underscores Genmab’s commitment to expanding its operational capabilities and market reach.

The most recent analyst rating on (GMAB) stock is a Buy with a $41.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Genmab Reports Strong Financial Growth and Announces Acquisition of Merus
Nov 6, 2025

On November 6, 2025, Genmab announced its financial results for the first nine months of 2025, reporting a 21% increase in revenue to $2,662 million, driven by higher royalties from DARZALEX and Kesimpta. The company also revealed its proposed acquisition of Merus N.V., a move expected to enhance its late-stage portfolio and accelerate its growth as a global biotechnology leader. This acquisition, valued at approximately $8 billion, is anticipated to close by early 2026, subject to customary conditions.

The most recent analyst rating on (GMAB) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Genmab stock, see the GMAB Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 13, 2025