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Biomarin Pharmaceutical Inc. (BMRN)
:BMRN

BioMarin Pharmaceutical (BMRN) AI Stock Analysis

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BioMarin Pharmaceutical

(NASDAQ:BMRN)

Rating:71Outperform
Price Target:
$64.00
▲(16.43%Upside)
BioMarin's overall stock score reflects strong financial performance and positive earnings call sentiment as the most significant factors. Technical analysis indicates current market weakness, while valuation suggests a fair price relative to earnings. Strategic growth initiatives and global revenue diversification buffer against market uncertainties.
Positive Factors
Business Strategy
BioMarin's recent deal with Inozyme is seen as a capital-efficient way to scale the ERT business, supporting the company's potential for diversification and growth.
Drug Development
BioMarin has the potential for long-term competitiveness with the development of its own once-weekly drug, BMN333, for achondroplasia.
Market Position
The analyst maintains a Buy rating for BioMarin, suggesting confidence in the company's future potential.
Negative Factors
Clinical Concerns
Concerns that BMRN raised during their earnings call, namely durability of effects and potential of hGH-associated longer-term side effects, are still valid.
Competition
Voxzogo faces potential competitive headwinds from Ascendis' TransCon CNP, which could lead to patient switches as the drug secures approval in various countries.
Market Share
A quarter of Voxzogo-treated patients could switch to TransCon CNP, which poses a risk to maintaining Voxzogo's patient base.

BioMarin Pharmaceutical (BMRN) vs. SPDR S&P 500 ETF (SPY)

BioMarin Pharmaceutical Business Overview & Revenue Model

Company DescriptionBioMarin Pharmaceutical Inc. is a biotechnology company that specializes in developing and commercializing innovative biopharmaceuticals for serious and life-threatening rare genetic diseases. Headquartered in San Rafael, California, BioMarin operates within the healthcare and biotechnology sectors, focusing on enzyme replacement therapies and gene therapies. Its core products include treatments for conditions such as phenylketonuria (PKU), mucopolysaccharidosis (MPS) disorders, and achondroplasia.
How the Company Makes MoneyBioMarin Pharmaceutical makes money primarily through the sale of its proprietary biopharmaceutical products. The company's revenue streams are driven by the commercialization of its approved therapies, which are often high-priced due to their specificity and effectiveness in treating rare diseases. Key revenue-generating products include Vimizim, Naglazyme, and Palynziq, among others. Additionally, BioMarin invests in research and development to expand its product pipeline, which could lead to future revenue opportunities. The company also engages in strategic partnerships and collaborations with other pharmaceutical firms and research institutions to enhance its product offerings and market reach, contributing to its earnings.

BioMarin Pharmaceutical Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Breaks down revenue across different business units, highlighting which products or services drive the most sales and indicating areas of growth or potential risk.
Chart InsightsBioMarin's revenue growth is driven by VOXZOGO, which has seen a significant increase, reflecting strong global demand. PALYNZIQ also contributes to growth with a 22% rise. The earnings call highlights a strategic focus on innovation and global diversification, with two-thirds of revenue from outside the U.S., providing stability against local economic fluctuations. However, VOXZOGO's revenue dynamics may face challenges due to global order patterns, with most growth anticipated in the latter half of 2025. BioMarin's robust pipeline and strategic initiatives position it well for future growth.
Data provided by:Main Street Data

BioMarin Pharmaceutical Earnings Call Summary

Earnings Call Date:May 01, 2025
(Q1-2025)
|
% Change Since: -12.34%|
Next Earnings Date:Aug 05, 2025
Earnings Call Sentiment Positive
BioMarin reported strong financial performance with notable revenue growth and profitability expansion, supported by successful pipeline progress. However, potential challenges include analyzing exposure to future pharmaceutical tariffs and managing VOXZOGO's revenue dynamics amid global order patterns. The overall sentiment leans towards optimism with strategic growth initiatives and robust financial results.
Q1-2025 Updates
Positive Updates
Strong Revenue Growth
BioMarin reported a 15% increase in total revenues for Q1 2025, reaching $745 million compared to the same period last year. VOXZOGO's global revenue also increased by 40% year-over-year.
Profitability Expansion
Non-GAAP earnings per share reached $1.13, representing a 59% year-over-year increase. Non-GAAP operating margin expanded by 11.9 percentage points year-over-year to 35.7%.
Pipeline Progress
Completed enrollment in a pivotal Phase 3 study with VOXZOGO in children with hypochondroplasia, aiming for a launch in 2027. Progress in BMN 351 for Duchenne Muscular Dystrophy and BMN 333, with early clinical results expected later this year.
Enzyme Therapies Growth
Revenue from the Enzyme Therapies business unit grew 8% year-over-year, with PALYNZIQ increasing by 22% compared to Q1 2024.
Geographical Revenue Diversification
Approximately two-thirds of BioMarin’s total revenues originate from outside the United States, providing insulation from US-specific economic conditions.
Negative Updates
Potential Tariff Impact
BioMarin is analyzing potential exposure to pharmaceutical tariffs under multiple scenarios, although they currently have immaterial exposure to US tariffs for China, Mexico, and Canada.
VOXZOGO Revenue Dynamics
Despite patient growth, quarterly revenues for VOXZOGO appear relatively similar quarter-to-quarter due to global order dynamics, with revenue growth expected mostly in the second half of 2025.
Company Guidance
In the BioMarin Pharmaceuticals First Quarter 2025 Conference Call, the company reported a strong financial performance with a 15% increase in revenue, reaching $745 million, and a 59% year-over-year rise in non-GAAP earnings per share, which stood at $1.13. The growth was fueled by VOXZOGO, which saw a 40% increase in global revenue to $214 million, and PALYNZIQ, which grew by 22%. The non-GAAP operating margin expanded to 35.7%, up by 11.9 percentage points from the previous year. The company reiterated its full-year non-GAAP operating margin guidance of 32% to 33%. BioMarin projects full-year 2025 VOXZOGO revenues between $900 million and $950 million, reflecting a 26% increase at the midpoint. The company also highlighted its strategic transformation, ongoing innovation, and robust global presence as key factors positioning it well amidst market uncertainties, with two-thirds of its revenue originating outside the United States.

BioMarin Pharmaceutical Financial Statement Overview

Summary
BioMarin demonstrates strong financial performance with significant revenue growth, improved profit margins, and robust cash flow management. The financial stability is highlighted by a low debt-to-equity ratio and strong equity financing, although debt levels need monitoring.
Income Statement
85
Very Positive
BioMarin Pharmaceutical has demonstrated a robust financial performance with strong revenue growth, rising from $2.09 billion in 2022 to $2.93 billion TTM (Trailing-Twelve-Months). The gross profit margin remains healthy, supported by efficient cost management. The net profit margin and EBIT margins have also shown significant improvement, indicating enhanced profitability. The consistent EBITDA margin growth highlights operational efficiency gains.
Balance Sheet
78
Positive
The company's balance sheet is strong, characterized by a low debt-to-equity ratio, suggesting prudent financial leverage. The equity ratio is impressive, indicating a high level of asset financing through equity. The return on equity has improved substantially, showcasing the company's ability to generate profits from shareholders' investments. However, the company should continue monitoring its debt levels to maintain financial flexibility.
Cash Flow
82
Very Positive
BioMarin Pharmaceutical has demonstrated strong cash flow dynamics with significant growth in free cash flow, reflecting effective capital expenditure management. The operating cash flow to net income ratio is favorable, indicating robust cash generation capabilities. The improved free cash flow to net income ratio further underscores the company's solid cash flow management.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.94B2.85B2.42B2.10B1.85B1.86B
Gross Profit2.32B2.27B1.84B1.61B1.38B1.34B
EBITDA738.30M650.86M310.28M267.51M48.03M-5.85M
Net Income523.88M426.86M167.65M141.56M-64.08M854.03M
Balance Sheet
Total Assets7.15B6.99B6.84B6.38B6.00B5.85B
Cash, Cash Equivalents and Short-Term Investments1.27B1.14B1.07B1.29B1.01B1.07B
Total Debt595.65M602.71M1.10B1.08B1.08B1.08B
Total Liabilities1.35B1.33B1.89B1.77B1.73B1.74B
Stockholders Equity5.79B5.66B4.95B4.60B4.27B4.11B
Cash Flow
Free Cash Flow620.18M475.42M51.65M44.36M185.31M-52.15M
Operating Cash Flow700.26M572.84M159.26M175.90M304.54M85.36M
Investing Cash Flow122.49M136.49M-111.24M-20.03M-366.31M-53.62M
Financing Cash Flow-522.43M-526.45M-18.73M-18.65M-48.00K181.12M

BioMarin Pharmaceutical Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price54.97
Price Trends
50DMA
58.36
Negative
100DMA
62.71
Negative
200DMA
64.86
Negative
Market Momentum
MACD
-0.98
Negative
RSI
48.66
Neutral
STOCH
61.68
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BMRN, the sentiment is Neutral. The current price of 54.97 is below the 20-day moving average (MA) of 55.73, below the 50-day MA of 58.36, and below the 200-day MA of 64.86, indicating a neutral trend. The MACD of -0.98 indicates Negative momentum. The RSI at 48.66 is Neutral, neither overbought nor oversold. The STOCH value of 61.68 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for BMRN.

BioMarin Pharmaceutical Risk Analysis

BioMarin Pharmaceutical disclosed 46 risk factors in its most recent earnings report. BioMarin Pharmaceutical reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioMarin Pharmaceutical Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
84
Outperform
$11.91B20.0030.22%24.49%244.87%
78
Outperform
$12.72B11.6022.69%25.11%46.46%
76
Outperform
$12.82B11.4719.94%19.85%21.16%
74
Outperform
$13.23B210.710.47%17.13%-88.78%
71
Outperform
$10.58B20.409.64%17.99%152.10%
52
Neutral
$10.40B357.68%10.69%34.71%
51
Neutral
$7.44B0.40-61.90%2.33%17.14%1.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BMRN
BioMarin Pharmaceutical
56.19
-24.79
-30.61%
EXEL
Exelixis
43.62
21.66
98.63%
INCY
Incyte
68.73
11.07
19.20%
UTHR
United Therapeutics
290.91
-20.13
-6.47%
ASND
Ascendis Pharma
172.00
37.82
28.19%
GMAB
Genmab
20.74
-4.41
-17.53%

BioMarin Pharmaceutical Corporate Events

Shareholder MeetingsBusiness Operations and Strategy
BioMarin Pharmaceutical Approves Equity Plan Amendment
Positive
May 22, 2025

On May 20, 2025, BioMarin Pharmaceutical Inc. held its Annual Meeting of Stockholders, where stockholders approved an amendment to the 2017 Equity Incentive Plan, increasing the number of shares reserved for issuance by 8,000,000. This amendment, effective immediately, was previously approved by the Compensation Committee, indicating strong internal support for expanding equity incentives. Additionally, stockholders elected ten directors, ratified KPMG LLP as the independent registered public accounting firm, and approved executive compensation, reflecting continued confidence in the company’s leadership and strategic direction.

The most recent analyst rating on (BMRN) stock is a Buy with a $120.00 price target. To see the full list of analyst forecasts on BioMarin Pharmaceutical stock, see the BMRN Stock Forecast page.

M&A TransactionsBusiness Operations and Strategy
BioMarin Acquires Inozyme Pharma for $270 Million
Positive
May 16, 2025

On May 16, 2025, BioMarin Pharmaceutical Inc. announced an agreement to acquire Inozyme Pharma, Inc. for approximately $270 million. This acquisition aims to enhance BioMarin’s enzyme therapy portfolio by adding INZ-701, a late-stage enzyme replacement therapy for ENPP1 Deficiency, a rare genetic condition. The transaction is expected to close in the third quarter of 2025, pending regulatory approval and other conditions. The acquisition is strategically significant for BioMarin, as it aligns with their commitment to advancing treatments for serious genetic conditions, potentially offering the first treatment for ENPP1 Deficiency. The first pivotal data readout for INZ-701 in children is anticipated in early 2026, with a potential launch in 2027, marking a significant step forward in addressing unmet medical needs.

The most recent analyst rating on (BMRN) stock is a Buy with a $120.00 price target. To see the full list of analyst forecasts on BioMarin Pharmaceutical stock, see the BMRN Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 23, 2025