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Jazz Pharmaceuticals (JAZZ)
NASDAQ:JAZZ
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Jazz Pharmaceuticals (JAZZ) AI Stock Analysis

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JAZZ

Jazz Pharmaceuticals

(NASDAQ:JAZZ)

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Outperform 78 (OpenAI - 5.2)
Rating:78Outperform
Price Target:
$292.00
▲(15.02% Upside)
Action:Reiterated
Date:08/11/26
The score is driven primarily by strengthening financial performance (lower leverage and durable free cash flow) and a positive earnings update with raised 2026 revenue guidance and strong commercial execution. Technicals support the view with an established uptrend, while valuation is reasonable but lacks dividend support.
Positive Factors
Cash generation & liquidity
Consistent, accelerating free cash flow and a multi‑billion cash balance give Jazz durable financial flexibility. That cash supports R&D, label-expansion programs, M&A (e.g., Actio), debt paydown and funding new launches without relying on dilutive capital, reducing execution risk over 2–6 months.
Negative Factors
Historical profitability volatility
Past multi‑year earnings volatility demonstrates sensitivity to product mix, one‑time items and R&D cycles. That history makes near‑term earnings less predictable if pipeline or launch assumptions slip, raising forecasting and capital allocation risk over the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash generation & liquidity
Consistent, accelerating free cash flow and a multi‑billion cash balance give Jazz durable financial flexibility. That cash supports R&D, label-expansion programs, M&A (e.g., Actio), debt paydown and funding new launches without relying on dilutive capital, reducing execution risk over 2–6 months.
Read all positive factors

Jazz Pharmaceuticals Key Performance Indicators (KPIs)

Any
Any
Neroscience Revenue Breakdown
Neroscience Revenue Breakdown
Highlights revenue generated from neuroscience products, indicating the company's strength and focus in treating neurological disorders, and potential growth in this specialized market.
Chart InsightsXywav has taken over as the growth engine in sleep, largely replacing steeply eroding Xyrem sales and driving overall revenue expansion, a trend management confirmed with patient adds and mid‑teens growth; Epidiolex is a steady second pillar with durable double‑digit volume gains. Sunosi revenues have effectively exited the portfolio. The company’s pivot to newer sleep, epilepsy and oncology products improves upside but creates near‑term margin and competitive risk as management warned of H2 generic/wake‑promoter pressure and ongoing IP/litigation exposure.
Data provided by:The Fly

Jazz Pharmaceuticals (JAZZ) vs. SPDR S&P 500 ETF (SPY)

Jazz Pharmaceuticals Business Overview & Revenue Model

Company Description
Jazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally. The company offers Xywav to treat cataplexy or excessive daytime sleepiness (EDS) with narcolepsy and idio...
How the Company Makes Money
Jazz Pharmaceuticals makes money primarily by selling branded prescription drugs to healthcare providers and patients through pharmaceutical distribution channels. Its core revenue stream is net product revenue, which is driven by: (1) sales volum...

Jazz Pharmaceuticals Earnings Call Summary

Earnings Call Date:Aug 03, 2026
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Nov 11, 2026
Earnings Call Sentiment Positive
The call presented multiple strong commercial and pipeline wins — record revenue, raised guidance, double-digit growth across key brands (oncology +32%, Xywav +13%, Epidiolex +16%, Zepzelca +42%) and a solid balance sheet — while acknowledging manageable margin pressure from royalties, rising SG&A/R&D investments, label adjustments for Zepzelca second-line, and potential future competitive/generic risks for the oxybate franchise. On balance, the positive execution, guidance raise, cash generation and late-stage regulatory momentum outweigh the identified challenges.
Positive Updates
Record Quarterly Revenue and Raised Full-Year Guidance
Record revenue of $1.21 billion in 2Q26, up 16% year-over-year; updated 2026 revenue guidance raised to $4.60B–$4.75B driven by strong first-half performance.
Negative Updates
Gross Margin Pressure from Royalties
Non-GAAP adjusted gross margin declined slightly year-over-year, attributed to higher sales of Zepzelca and Modeyso which carry third-party royalties.
Read all updates
Q2-2026 Updates
Negative
Record Quarterly Revenue and Raised Full-Year Guidance
Record revenue of $1.21 billion in 2Q26, up 16% year-over-year; updated 2026 revenue guidance raised to $4.60B–$4.75B driven by strong first-half performance.
Read all positive updates
Company Guidance
Management raised 2026 revenue guidance to $4.60–$4.75 billion and set rare-sleep revenue at $2.025–$2.125 billion, citing record Q2 revenue of $1.21 billion (16% YoY), strong oncology growth (+32% Y/Y), and robust first‑half operating cash flow of $824 million and $2.2 billion cash on the balance sheet; they expect double‑digit Xywav growth in 2026, modestly higher SG&A guidance (non‑GAAP SG&A and R&D each rose 11% this quarter), a slightly lower non‑GAAP gross margin, a non‑GAAP effective tax rate moderately above prior guidance, updated fully diluted share count guidance to 69–70 million shares, and reported Q2 non‑GAAP EPS of $5.71 (including $0.94 of IPR&D charges), with product-level drivers including Xywav Q2 sales of $471 million (~525 net patient adds; ~17,125 active patients, >12% YoY), Epidiolex $292 million (16% Y/Y; ~12% volume growth), Zepzelca $106 million (42% Y/Y), Modeyso $48 million and Ziihera $15 million.

Jazz Pharmaceuticals Financial Statement Overview

Summary
Improving fundamentals supported by strong TTM profitability (~20% net margin), meaningfully reduced leverage (debt-to-equity ~0.22 in TTM), and consistently positive/accelerating free cash flow. Score is held back by historically uneven earnings with multiple loss years despite the recent rebound.
Income Statement
74
Positive
Balance Sheet
78
Positive
Cash Flow
85
Very Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue4.60B4.27B4.07B3.83B3.66B3.09B
Gross Profit3.90B3.76B3.62B3.40B3.12B2.65B
EBITDA1.48B108.46M1.52B1.45B1.47B1.03B
Net Income940.76M-356.15M560.12M414.83M-224.06M-328.95M
Balance Sheet
Total Assets11.08B11.66B12.01B11.39B10.84B12.30B
Cash, Cash Equivalents and Short-Term Investments2.20B2.44B2.99B1.63B881.48M591.45M
Total Debt4.41B5.42B6.16B5.79B5.81B6.15B
Total Liabilities6.28B7.34B7.92B7.66B7.75B8.33B
Stockholders Equity4.80B4.32B4.09B3.74B3.09B3.97B
Cash Flow
Free Cash Flow1.54B1.15B1.35B1.07B773.78M732.98M
Operating Cash Flow1.66B1.36B1.40B1.09B1.27B778.51M
Investing Cash Flow-221.96M-1.51B-508.19M-163.06M-446.23M-5.21B
Financing Cash Flow-1.01B-873.38M20.52M-305.25M-529.49M3.97B

Jazz Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price253.87
Price Trends
50DMA
243.47
Positive
100DMA
228.13
Positive
200DMA
198.33
Positive
Market Momentum
MACD
1.34
Positive
RSI
54.22
Neutral
STOCH
34.18
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JAZZ, the sentiment is Positive. The current price of 253.87 is above the 20-day moving average (MA) of 253.62, above the 50-day MA of 243.47, and above the 200-day MA of 198.33, indicating a neutral trend. The MACD of 1.34 indicates Positive momentum. The RSI at 54.22 is Neutral, neither overbought nor oversold. The STOCH value of 34.18 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JAZZ.

Jazz Pharmaceuticals Risk Analysis

Jazz Pharmaceuticals disclosed 47 risk factors in its most recent earnings report. Jazz Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Jazz Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
80
Outperform
$11.69B29.26180.63%41.15%-21.44%
78
Outperform
$16.12B16.7621.37%12.59%
78
Outperform
$12.67B225.338.37%16.02%-59.24%
72
Outperform
$11.33B61.878.90%0.45%-0.38%152.69%
64
Neutral
$26.18B-95.37-6.12%-67.58%45.61%
58
Neutral
$45.44B-23.93-96.44%-95.67%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JAZZ
Jazz Pharmaceuticals
253.07
133.87
112.31%
CORT
Corcept Therapeutics
118.10
47.91
68.26%
HALO
Halozyme
104.89
34.91
49.89%
TECH
Bio-Techne
72.22
17.60
32.22%
RVMD
Revolution Medicines
216.00
179.46
491.13%
ROIV
Roivant Sciences
37.37
25.61
217.77%

Jazz Pharmaceuticals Corporate Events

Business Operations and StrategyM&A Transactions
Jazz Pharmaceuticals to Acquire Actio Biosciences in Merger
Positive
Aug 10, 2026
On August 10, 2026, Jazz Pharmaceuticals, Inc. agreed to acquire Actio Biosciences, Inc. in a cash-based merger valued at an initial $820 million, with customary balance sheet adjustments, making Actio a wholly owned subsidiary. The deal structure...
Business Operations and StrategyM&A Transactions
Jazz Pharmaceuticals to Acquire Rare Epilepsy Specialist Actio
Positive
Aug 10, 2026
On August 10, 2026, Jazz Pharmaceuticals agreed to acquire privately held Actio Biosciences in a deal featuring an $820 million upfront payment and up to $500 million in milestone-based contingent consideration. The transaction, unanimously approv...
Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
Jazz Pharmaceuticals Shareholders Reaffirm Board and Governance Plans
Positive
Jul 24, 2026
At its July 23, 2026 annual general meeting in Dublin, Jazz Pharmaceuticals’ shareholders elected three directors—Bruce C. Cozadd, Heather Ann McSharry and Rick E. Winningham—to serve until the 2029 annual meeting, signaling cont...
Executive/Board Changes
Jazz Pharmaceuticals announces planned board leadership transition
Neutral
May 29, 2026
On May 25, 2026, Jazz Pharmaceuticals disclosed that Anne O’Riordan, a Class III director whose term ends at the 2026 annual meeting, has notified the board that she will not stand for re-election. The company said her departure is not due t...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 11, 2026