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Royalty Pharma PLC (RPRX)
NASDAQ:RPRX
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Royalty Pharma (RPRX) AI Stock Analysis

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RPRX

Royalty Pharma

(NASDAQ:RPRX)

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Outperform 79 (OpenAI - 5.2)
Rating:79Outperform
Price Target:
$63.00
▲(26.00% Upside)
Action:Reiterated
Date:06/05/26
The score is driven primarily by strong financial performance (high profitability and exceptional free-cash-flow generation) and constructive technical momentum (price above key moving averages with positive MACD). The raised guidance and positive earnings-call tone further support the outlook, while valuation is the main drag given the higher P/E and only modest dividend yield.
Positive Factors
Cash generation
Very strong and consistent cash generation provides durable capacity to fund acquisitions, support dividend increases and buybacks, and service interest. High FCF to net income and cash coverage (~4.9x) materially improve financial flexibility even if revenue timing fluctuates.
Negative Factors
Elevated interest expense
Material interest outlays are a persistent cash drag given sizeable debt stock. Semiannual timing swings can compress quarterly cash available for reinvestment or distributions, and higher-for-longer rates would structurally increase financing costs and reduce net cash returns.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash generation
Very strong and consistent cash generation provides durable capacity to fund acquisitions, support dividend increases and buybacks, and service interest. High FCF to net income and cash coverage (~4.9x) materially improve financial flexibility even if revenue timing fluctuates.
Read all positive factors

Royalty Pharma Key Performance Indicators (KPIs)

Any
Any
Portfolio Receipts
Portfolio Receipts
Tracks the income generated from the company's portfolio of royalty interests, highlighting cash flow stability and the effectiveness of its investment strategy in acquiring lucrative royalty streams.
Chart InsightsPortfolio receipts have trended higher and become more stepwise—driven by large, discrete royalty acquisitions and milestone timing rather than steady organic growth. Management’s recent 11% quarterly growth and repeated guidance raises reflect successful capital deployment (high ROIC/ROE) and active deal flow, but receipts are now more sensitive to transaction cadence and the upcoming Promacta cliff in 2026; rising interest costs mean higher gross receipts won’t fully cushion earnings or free cash without continued accretive deals.
Data provided by:The Fly

Royalty Pharma (RPRX) vs. SPDR S&P 500 ETF (SPY)

Royalty Pharma Business Overview & Revenue Model

Company Description
Royalty Pharma plc, headquartered in New York City and founded in 1996, operates within the United States as a key player in the biopharmaceutical industry. The company primarily focuses on the acquisition of royalties from biopharmaceutical produ...
How the Company Makes Money
Royalty Pharma makes money primarily by collecting royalty and similar payments that are contractually based on the net sales of specific biopharmaceutical products. Its core revenue stream is “portfolio receipts” (cash inflows from its royalty in...

Royalty Pharma Earnings Call Summary

Earnings Call Date:May 06, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 12, 2026
Earnings Call Sentiment Positive
The call was strongly positive: Royalty Pharma reported double-digit recurring revenue growth, attractive returns (ROIC ~14.1%, ROIE ~19.7%), robust cash generation ($722M portfolio cash flow), active capital deployment (>$0.5B) and strategic deal flow including R&D co-funding momentum (J&J and Teva deals) and high-impact clinical/regulatory wins (daraxonrasib, Avlayah, Myqorzo). Key risks highlighted were a material decline in milestone receipts (~53% drop), elevated interest expense timing, some market/policy headwinds (Promacta LOE, biosimilar Tysabri, MFN uncertainty) and optionality/execution risk in future co-funding tranches. Overall, the positive operating and balance-sheet trends and raised guidance outweigh the limited but meaningful risks discussed.
Positive Updates
Top-line and Recurring Cash Flow Growth
Portfolio receipts grew 10% in Q1 and royalty receipts (recurring cash flows) grew 13% year-over-year, driven by strong performances from Tremfya, Voranigo and Evrysdi; the company absorbed a ~3% headwind from loss of exclusivity on Promacta and still delivered double-digit royalty growth.
Negative Updates
Decline in Milestones and Other Contractual Receipts
Significant year-over-year decline in milestones and other contractual receipts; expected drop from $128 million in 2025 to approximately $60 million in 2026 (a decline of ~53%), which weighed on portfolio receipts growth versus recurring royalties.
Read all updates
Q1-2026 Updates
Negative
Top-line and Recurring Cash Flow Growth
Portfolio receipts grew 10% in Q1 and royalty receipts (recurring cash flows) grew 13% year-over-year, driven by strong performances from Tremfya, Voranigo and Evrysdi; the company absorbed a ~3% headwind from loss of exclusivity on Promacta and still delivered double-digit royalty growth.
Read all positive updates
Company Guidance
Royalty Pharma raised its 2026 full‑year portfolio receipts guidance to $3.325–$3.45 billion (from $3.275–$3.425B), with royalty receipts expected to grow ~4%–8%; Q2 portfolio receipts are guided at $740–$760 million. Management expects milestones and other contractual receipts to decline from $128 million in 2025 to roughly $60 million in 2026, operating and professional costs to run about 5.5%–6.5% of portfolio receipts (Q1 was 3.9%), and interest paid to be ~$350–$360 million for the year (with ≈$175M due in Q3 and de minimis in Q2 and Q4); interest received (not included) was $6M in Q1. Q1 portfolio cash flow (adjusted EBITDA less net interest) was $722M, net interest paid was $167M, net margin ~78%, capital deployed in Q1 was $528M and the company returned ≈$186M to shareholders (including $50M of buybacks for 1M shares and a 7% dividend increase). On the balance sheet, cash and equivalents were $586M at March 31, investment‑grade debt outstanding was $9.2B with a ~12‑year weighted average duration, Fitch upgraded the rating to BBB (from BBB‑), leverage stood at 2.9x total debt/adjusted EBITDA (2.7x net), the $1.8B revolver is undrawn, and management cites roughly $4 billion of total financial flexibility.

Royalty Pharma Financial Statement Overview

Summary
Strong TTM profitability (EBIT margin ~46%, net margin ~34%) and standout cash generation (TTM operating cash flow and free cash flow ~ $2.65B; FCF to net income 1.0). Offsetting factors include meaningful debt (TTM debt-to-equity ~0.90) and historically volatile revenue/profit trends.
Income Statement
78
Positive
Balance Sheet
62
Positive
Cash Flow
88
Very Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.44B2.38B2.26B2.35B2.24B2.29B
Gross Profit2.44B2.38B2.26B2.35B2.24B2.29B
EBITDA1.70B1.64B1.56B1.89B423.69M1.43B
Net Income827.60M770.95M858.98M1.13B42.83M619.73M
Balance Sheet
Total Assets19.82B19.62B18.22B16.38B16.81B17.52B
Cash, Cash Equivalents and Short-Term Investments608.29M637.50M1.77B1.23B2.43B2.80B
Total Debt8.96B8.95B7.61B6.14B7.12B7.10B
Total Liabilities9.88B9.91B7.88B6.30B7.29B7.27B
Stockholders Equity6.89B6.48B6.95B6.53B5.63B5.78B
Cash Flow
Free Cash Flow2.65B2.49B2.77B2.99B2.14B2.02B
Operating Cash Flow2.65B2.49B2.77B2.99B2.14B2.02B
Investing Cash Flow-2.64B-1.61B-2.68B-2.07B-1.03B-1.87B
Financing Cash Flow-517.34M-1.19B361.14M-2.15B-944.86M385.11M

Royalty Pharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price50.00
Price Trends
50DMA
51.51
Positive
100DMA
48.10
Positive
200DMA
42.74
Positive
Market Momentum
MACD
1.00
Positive
RSI
53.88
Neutral
STOCH
34.65
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RPRX, the sentiment is Positive. The current price of 50 is below the 20-day moving average (MA) of 54.41, below the 50-day MA of 51.51, and above the 200-day MA of 42.74, indicating a neutral trend. The MACD of 1.00 indicates Positive momentum. The RSI at 53.88 is Neutral, neither overbought nor oversold. The STOCH value of 34.65 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RPRX.

Royalty Pharma Risk Analysis

Royalty Pharma disclosed 58 risk factors in its most recent earnings report. Royalty Pharma reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Royalty Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
84
Outperform
$21.68B14.2029.31%21.48%1853.63%
79
Outperform
$31.60B28.3212.67%2.23%7.79%-22.14%
79
Outperform
$23.17B18.5719.24%5.87%8.18%
63
Neutral
$14.99B18.5020.51%21.02%-24.83%
62
Neutral
$13.60B23.45-5641.90%155.14%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$22.90B-15.82-6.67%10.01%-71.78%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RPRX
Royalty Pharma
54.27
19.91
57.94%
INCY
Incyte
101.98
30.76
43.19%
UTHR
United Therapeutics
549.57
261.01
90.45%
ASND
Ascendis Pharma
223.29
45.58
25.65%
GMAB
Genmab
24.58
1.72
7.52%
BNTX
BioNTech SE
90.80
-15.53
-14.61%

Royalty Pharma Corporate Events

Business Operations and StrategyExecutive/Board ChangesStock BuybackShareholder Meetings
Royalty Pharma Shareholders Back Board, Pay and Flexibility
Positive
Jun 4, 2026
On June 4, 2026, Royalty Pharma held its 2026 Annual General Meeting of Shareholders, where investors representing 88.08% of voting power participated, establishing a strong quorum and signaling solid shareholder engagement. All nine director nomi...
Business Operations and StrategyPrivate Placements and Financing
Royalty Pharma Secures New $1.8 Billion Credit Facility
Positive
May 28, 2026
On May 22, 2026, Royalty Pharma plc entered into a new $1.8 billion unsecured revolving credit facility with a syndicate of lenders led by Bank of America, replacing its prior revolving credit agreement from 2021 and fully repaying and terminating...
Business Operations and StrategyPrivate Placements and FinancingProduct-Related Announcements
Royalty Pharma Expands Daraxonrasib Royalty Stake After Milestone
Positive
Apr 13, 2026
On April 13, 2026, Revolution Medicines reported positive Phase 3 results for its RAS(ON) inhibitor daraxonrasib in previously treated metastatic pancreatic cancer, fulfilling primary and key secondary endpoints and supporting planned global regul...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 05, 2026