Royalty Pharma (RPRX) AI Stock Analysis

• Market Cap: $21.29B
• Dividend Yield: 2.39%
• Average Volume (3M): 2.92M
• Price to Earnings (P/E): 15.9
• Beta (1Y): 0.30
• Revenue Growth: 3.04%
• EPS Growth: 53.03%
• Country: US
• Employees: 75
• Sector: Healthcare
• Sector Strength: 49
• Industry: Biotechnology
• EPS (TTM): 1.14
• Shares Outstanding: 432,293,060
• 10 Day Avg. Volume: 3,450,653
• 30 Day Avg. Volume: 2,917,518
• PEG Ratio: N/A
• Price to Book (P/B): N/A
• Price to Sales (P/S): N/A
• P/FCF Ratio: N/A
• Enterprise Value/Market Cap: 1.45
• Enterprise Value/Revenue: 13.35
• Enterprise Value/Gross Profit: 17.85
• Enterprise Value/Ebitda: 16.27
• 1Y Price Target: $43.33
• Price Target Upside: 19.20% Upside
• Rating Consensus: Strong Buy
• Number of Analyst Covering: 6

• Rating: 78 Outperform
• Price Target: $42.00 ▲(15.54% Upside)

Royalty Pharma's strong operational efficiency and positive earnings call are the most significant factors driving the score. The stock's technical indicators show positive momentum, and its valuation is reasonable. Corporate governance improvements further support the stock's outlook. However, challenges in profitability and a royalty dispute with Vertex present risks.

Positive Factors

Oncology Asset Upside

The announced royalty financing deal with Revolution Medicines allows Royalty Pharma to participate in the upside of the target asset daraxonrasib for oncology.

Regulatory Achievements

FDA has granted Breakthrough Therapy Designation to daraxonrasib for previously treated metastatic PDAC in patients with KRAS G12 mutations.

Strategic Direction

The transaction sets Royalty Pharma on track to meet or exceed its 5-year capital deployment target, demonstrating confidence in their strategic direction.

Negative Factors

Market Competition

Tremfya should fight Skyrizi to a draw in ulcerative colitis, and RPRX garners a tiered mid-single digit royalty on Tremfya through 2031-32.

Pipeline Challenges

The company can adapt to potential changes in the regulatory environment due to the absence of an internal pipeline.

Royalty Pharma Business Overview & Revenue Model

Company Description

Royalty Pharma plc operates as a buyer of biopharmaceutical royalties and a funder of innovations in the biopharmaceutical industry in the United States. It is also involved in the identification, evaluation, and acquisition of royalties on various biopharmaceutical therapies. In addition, the company collaborates with innovators from academic institutions, research hospitals and not-for-profits, small and mid-cap biotechnology companies, and pharmaceutical companies. Its portfolio consists of royalties on approximately 35 marketed therapies and 10 development-stage product candidates that address various therapeutic areas, such as rare disease, cancer, neurology, infectious disease, hematology, and diabetes. The company was founded in 1996 and is based in New York, New York.

How the Company Makes Money

Royalty Pharma makes money by acquiring royalty interests in drugs and biopharmaceutical products from various stakeholders, including academic institutions, research hospitals, and pharmaceutical companies. The company's primary revenue stream comes from the royalties it receives from the sales of these drugs, which can include treatments for a wide range of medical conditions. Royalty Pharma strategically invests in high-potential drugs and typically pays the original innovators a lump sum in exchange for a portion of future sales revenue. This model allows Royalty Pharma to benefit from the commercial success of these drugs. Additionally, the company often forms partnerships and collaborations to enhance its portfolio and maximize its revenue potential. Key factors contributing to its earnings include the success of the drugs in its portfolio, market expansion, and strategic acquisitions of new royalty interests.

Royalty Pharma Financial Statement Overview

Summary

Royalty Pharma demonstrates strong operational efficiency with impressive gross margins and robust cash flow generation. However, challenges in net income growth and profitability impact the overall financial health. Despite moderate leverage and strong equity levels, the company should focus on enhancing profitability to improve financial performance.

Income Statement

The income statement shows stable revenue with a slight decline over the TTM period compared to previous years. Gross profit margins remain strong, over 99%, indicating efficient cost management. However, the net profit margin has decreased due to higher expenses relative to revenue. The EBIT and EBITDA margins show strong operational efficiency, though the decline in net income suggests some profitability challenges.

Balance Sheet

The balance sheet indicates a moderate debt-to-equity ratio, suggesting manageable leverage levels. The equity ratio is stable, supporting financial stability. However, the return on equity (ROE) fluctuates due to varying net income, highlighting potential profitability issues. Overall, the company maintains a solid asset base with appropriate equity levels.

Cash Flow

Cash flows are robust, with strong operating cash flow relative to net income, indicating efficient cash generation from operations. The free cash flow remains positive, supporting financial flexibility. However, the free cash flow growth rate has slowed, suggesting a need for future improvements in cash flow generation to sustain growth.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	2.31B	2.26B	2.35B	2.24B	2.29B	2.12B
Gross Profit	1.73B	2.26B	1.79B	2.23B	2.27B	2.03B
EBITDA	1.89B	1.29B	1.89B	928.56M	1.45B	1.68B
Net Income	1.02B	859.00M	1.13B	42.83M	478.75M	495.20M
Balance Sheet
Total Assets	18.32B	18.22B	16.38B	16.81B	17.52B	21.10B
Cash, Cash Equivalents and Short-Term Investments	645.11M	987.23M	495.31M	2.43B	2.80B	1.99B
Total Debt	8.02B	7.61B	6.14B	7.12B	7.10B	5.82B
Total Liabilities	8.82B	7.88B	6.30B	7.29B	7.27B	6.12B
Stockholders Equity	6.35B	6.95B	6.53B	5.63B	5.78B	9.90B
Cash Flow
Free Cash Flow	2.47B	2.77B	2.99B	2.14B	2.02B	2.03B
Operating Cash Flow	2.47B	2.77B	2.99B	2.14B	2.02B	2.03B
Investing Cash Flow	-1.56B	-2.68B	-2.07B	-1.03B	-1.87B	-2.76B
Financing Cash Flow	-2.04B	361.14M	-2.15B	-944.86M	385.11M	1.49B

Royalty Pharma Technical Analysis

• Technical Analysis Sentiment: Positive
• Last Price: 36.35
• 50DMA: Positive
• 100DMA: Positive
• 200DMA: Positive
• MACD: Positive
• RSI: Neutral
• STOCH: Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RPRX, the sentiment is Positive. The current price of 36.35 is below the 20-day moving average (MA) of 36.55, above the 50-day MA of 35.68, and above the 200-day MA of 31.23, indicating a neutral trend. The MACD of 0.20 indicates Positive momentum. The RSI at 51.20 is Neutral, neither overbought nor oversold. The STOCH value of 22.27 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RPRX.

Royalty Pharma Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
GMAB	84 Outperform	$14.07B	11.54	26.08%	―	23.25%	64.46%
RPRX	78 Outperform	$21.29B	15.89	15.92%	2.39%	3.04%	53.03%
INCY	75 Outperform	$16.82B	19.76	24.30%	―	18.87%	1088.27%
EXEL	73 Outperform	$10.31B	18.37	29.00%	―	10.73%	81.66%
BNTX	63 Neutral	$27.09B	―	-1.81%	―	7.51%	30.53%
Sector *	51 Neutral	kr6.00B	8.79	-28.70%	2.24%	51.61%	19.20%
MRNA	45 Neutral	$10.38B	―	-27.50%	―	-38.95%	51.07%

Royalty Pharma Corporate Events

Henry Fernandez Steps Down from Royalty Pharma Board

On August 13, 2025, Henry Fernandez stepped down from his role as Lead Independent Director of Royalty Pharma‘s Board of Directors. Fernandez, who joined the board in July 2020 and was appointed Lead Independent Director in March 2021, has been credited with helping the company achieve significant milestones and positioning it for future growth. His departure was not due to any disagreements with the company, and the board expressed gratitude for his contributions. Royalty Pharma plans to appoint a new Lead Independent Director soon.

The most recent analyst rating on (RPRX) stock is a Buy with a $42.00 price target. To see the full list of analyst forecasts on Royalty Pharma stock, see the RPRX Stock Forecast page.

Royalty Pharma Strengthens Board with New Appointments

On July 17, 2025, Royalty Pharma announced the appointment of Carole Ho and Elizabeth Weatherman to its Board of Directors, enhancing its corporate governance with over 90% independent representation. This move underscores the company’s commitment to governance following its acquisition of an external manager. Both appointees bring extensive experience in biopharma and finance, expected to support Royalty Pharma’s growth strategy and strengthen its board with their unique insights.

The most recent analyst rating on (RPRX) stock is a Buy with a $42.00 price target. To see the full list of analyst forecasts on Royalty Pharma stock, see the RPRX Stock Forecast page.

Royalty Pharma Completes Major Acquisition and Restructuring

Royalty Pharma has recently undergone significant restructuring and financial transactions. On May 16, 2024, RPH acquired all equity interests of RP LLC, involving a cash payment of $200 million and the issuance of 24,530,266 non-voting Class E ordinary shares. The transaction also included the assumption of a $380 million term loan facility. Additionally, the company amended its articles of association to provide new rights and streamline shareholder processes. These changes are expected to impact the company’s financial structure and governance, potentially influencing its market position and stakeholder relationships.

The most recent analyst rating on (RPRX) stock is a Buy with a $42.00 price target. To see the full list of analyst forecasts on Royalty Pharma stock, see the RPRX Stock Forecast page.