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Royalty Pharma PLC (RPRX)
NASDAQ:RPRX

Royalty Pharma (RPRX) AI Stock Analysis

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RPRX

Royalty Pharma

(NASDAQ:RPRX)

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Outperform 79 (OpenAI - 4o)
Rating:79Outperform
Price Target:
$44.00
▲(13.99% Upside)
Royalty Pharma's strong financial performance and positive earnings call are the most significant factors driving the stock's score. The company's robust profitability, strategic acquisitions, and raised guidance underscore its growth potential. While technical analysis and valuation suggest a stable outlook, the strategic corporate event further enhances its financial position. Overall, the stock is well-positioned for future growth in the biotechnology industry.
Positive Factors
Strategic Acquisitions
Strategic acquisitions enhance Royalty Pharma's portfolio, providing long-term revenue streams and strengthening its market position.
Pipeline Expansion
Expanding the pipeline to 17 therapies positions Royalty Pharma for future growth, with potential new revenue sources from successful drug launches.
Strong Financial Performance
Consistent growth in portfolio and royalty receipts underscores the company's robust financial health and ability to generate sustainable income.
Negative Factors
Declining Promacta Royalties
The decline in Promacta royalties due to generics impacts future revenue, highlighting the need for diversification in revenue streams.
Increased Interest Expenses
Rising interest expenses from recent debt issuance could pressure cash flow, affecting financial flexibility and profitability.
Negative Free Cash Flow Growth
Declining free cash flow growth may limit the company's ability to invest in new opportunities and manage debt, impacting long-term growth.

Royalty Pharma (RPRX) vs. SPDR S&P 500 ETF (SPY)

Royalty Pharma Business Overview & Revenue Model

Company DescriptionRoyalty Pharma plc operates as a buyer of biopharmaceutical royalties and a funder of innovations in the biopharmaceutical industry in the United States. It is also involved in the identification, evaluation, and acquisition of royalties on various biopharmaceutical therapies. In addition, the company collaborates with innovators from academic institutions, research hospitals and not-for-profits, small and mid-cap biotechnology companies, and pharmaceutical companies. Its portfolio consists of royalties on approximately 35 marketed therapies and 10 development-stage product candidates that address various therapeutic areas, such as rare disease, cancer, neurology, infectious disease, hematology, and diabetes. The company was founded in 1996 and is based in New York, New York.
How the Company Makes MoneyRoyalty Pharma generates revenue primarily through its portfolio of royalty interests in various biopharmaceutical products. The company acquires these royalties from other companies, often taking an upfront payment in exchange for a percentage of future sales from established drugs. This revenue model capitalizes on the success of marketed therapies, allowing Royalty Pharma to earn income as long as the drugs continue to generate sales. Key revenue streams include royalties from high-performing drugs in areas such as oncology, rare diseases, and infectious diseases. Additionally, Royalty Pharma has formed strategic partnerships and collaborations with leading biopharmaceutical companies, which enhance its revenue opportunities and provide access to new drugs in development. The company's ability to identify and invest in promising therapies is a significant factor contributing to its earnings.

Royalty Pharma Key Performance Indicators (KPIs)

Any
Any
Portfolio Receipts
Portfolio Receipts
Tracks the income generated from the company's portfolio of royalty interests, highlighting cash flow stability and the effectiveness of its investment strategy in acquiring lucrative royalty streams.
Chart InsightsRoyalty Pharma's Portfolio Receipts have shown significant growth, particularly in early 2023, reflecting a robust and diversified portfolio. The recent earnings call highlighted a 17% increase in Portfolio Receipts, driven by strong performance and strategic capital allocation, including a $2 billion share buyback plan. The company raised its full-year guidance, anticipating 6% to 12% growth, supported by promising developments like the Phase 3 R&D collaboration with Biogen. However, potential regulatory challenges and a royalty dispute with Vertex could pose risks to future growth.
Data provided by:The Fly

Royalty Pharma Earnings Call Summary

Earnings Call Date:Nov 05, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 17, 2026
Earnings Call Sentiment Positive
Royalty Pharma reported a strong financial performance with significant growth and strategic acquisitions in the third quarter of 2025, leading to an upward revision of its full-year guidance. Despite challenges such as the upcoming decline in Promacta royalties and increased interest expenses, the company's diversified portfolio and pipeline expansion underline its growth potential.
Q3-2025 Updates
Positive Updates
Strong Financial Performance
Royalty Pharma reported an 11% growth in both portfolio receipts and royalty receipts, driven by a diversified portfolio. The company raised its full-year 2025 guidance for portfolio receipts to $3.2 billion to $3.25 billion, representing growth of 14% to 16%.
Successful Capital Deployment
The company deployed $1 billion in the quarter on loyalty transactions, totaling $1.7 billion for the first 9 months. It also repurchased 4 million shares, totaling $1.15 billion in share repurchases for the year.
Strategic Acquisitions
Acquired royalty interests in Amgen's Imdelltra for up to $950 million, Zenas Biopharma's obexelimab for up to $300 million, and Alnylam's Amvuttra for $310 million.
Pipeline Expansion
Development-stage pipeline expanded to 17 therapies, with expectations of multiple pivotal readouts in the near future. The pipeline is expected to generate over $36 billion in cumulative peak sales.
Consistent Returns
Return on invested capital maintained at 15.7% and return on invested equity at 22.9%.
Negative Updates
Upcoming Challenges with Promacta
Minimal royalties from Promacta expected in 2026 due to the launch of generics in the United States and Europe in 2025.
Increased Interest Expenses
Interest paid is expected to be between $350 million to $360 million in 2026, including interest payments on $2 billion of senior secured notes issued in September 2025.
Company Guidance
During Royalty Pharma's third quarter earnings call, the company reported a robust 11% growth in both portfolio and royalty receipts, showcasing the strength of its diversified portfolio. The company also introduced new quarterly metrics, revealing a return on invested capital of 15.7% and a return on invested equity of 22.9% for the past 12 months. Throughout the quarter, Royalty Pharma deployed $1 billion on value-creating transactions, raising its full-year top-line guidance for 2025 to $3.2 billion to $3.25 billion, representing a 14% to 16% growth. The company completed several significant transactions, including a $950 million royalty interest acquisition on Amgen's Imdelltra and a $310 million royalty on Alnylam's Amvuttra. Additionally, Royalty Pharma repurchased 4 million shares, totaling $1.15 billion in share buybacks for the year, and expanded its development-stage pipeline to 17 therapies. The guidance increase marks the third raise this year and the 14th since the company's IPO in 2020.

Royalty Pharma Financial Statement Overview

Summary
Royalty Pharma exhibits strong financial health with high profitability, efficient cash flow management, and a solid equity base. While revenue growth is stable, the company shows potential for further expansion. Leverage is moderate, and cash flow generation remains robust, although recent free cash flow growth has declined slightly.
Income Statement
85
Very Positive
Royalty Pharma demonstrates strong profitability with a consistent gross profit margin of 100% and a robust EBIT margin of 83.76% in TTM. The net profit margin has improved to 44.28% in TTM, indicating enhanced efficiency. Revenue growth is modest at 1.94% in TTM, showing stability but limited expansion. Overall, the company maintains high profitability and stable revenue growth.
Balance Sheet
78
Positive
The company's debt-to-equity ratio stands at 1.26 in TTM, indicating moderate leverage. Return on equity is healthy at 15.20%, reflecting effective use of equity to generate profits. The equity ratio is not directly provided, but the balance sheet shows a solid equity base. While leverage is slightly high, the company maintains a strong equity position and profitability.
Cash Flow
80
Positive
Operating cash flow to net income ratio is strong at 2.05 in TTM, indicating efficient cash generation relative to net income. Free cash flow to net income ratio is stable at 1.0, showing consistent cash flow management. However, free cash flow growth is negative at -2.55%, suggesting a slight decline in cash flow generation. Overall, cash flow metrics are solid, with some room for improvement in growth.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.35B2.26B2.35B2.24B2.29B2.12B
Gross Profit2.35B2.26B2.35B2.24B2.29B1.89B
EBITDA1.58B1.56B1.89B423.69M1.43B1.68B
Net Income764.96M858.98M1.13B42.83M619.73M975.04M
Balance Sheet
Total Assets19.35B18.22B16.38B16.81B17.52B16.02B
Cash, Cash Equivalents and Short-Term Investments955.04M1.77B1.23B2.43B2.80B2.65B
Total Debt8.97B7.61B6.14B7.12B7.10B5.82B
Total Liabilities9.73B7.88B6.30B7.29B7.27B6.12B
Stockholders Equity6.41B6.95B6.53B5.63B5.78B4.82B
Cash Flow
Free Cash Flow2.41B2.77B2.99B2.14B2.02B2.03B
Operating Cash Flow2.41B2.77B2.99B2.14B2.02B2.03B
Investing Cash Flow-1.27B-2.68B-2.07B-1.03B-1.87B-2.76B
Financing Cash Flow-1.14B361.14M-2.15B-944.86M385.11M1.49B

Royalty Pharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price38.60
Price Trends
50DMA
38.17
Positive
100DMA
37.07
Positive
200DMA
35.14
Positive
Market Momentum
MACD
-0.01
Positive
RSI
49.57
Neutral
STOCH
38.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RPRX, the sentiment is Positive. The current price of 38.6 is below the 20-day moving average (MA) of 39.02, above the 50-day MA of 38.17, and above the 200-day MA of 35.14, indicating a neutral trend. The MACD of -0.01 indicates Positive momentum. The RSI at 49.57 is Neutral, neither overbought nor oversold. The STOCH value of 38.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RPRX.

Royalty Pharma Risk Analysis

Royalty Pharma disclosed 59 risk factors in its most recent earnings report. Royalty Pharma reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Royalty Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
81
Outperform
$20.16B17.2330.39%18.09%3563.21%
79
Outperform
$22.28B22.0711.51%2.28%3.72%-31.46%
79
Outperform
$22.27B19.6020.04%13.50%17.16%
76
Outperform
$19.87B13.6428.20%24.98%127.06%
53
Neutral
$22.24B-35.16-2.94%7.04%-25.24%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$12.22B-47.09103.32%47.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RPRX
Royalty Pharma
38.60
13.97
56.72%
INCY
Incyte
102.69
32.85
47.04%
UTHR
United Therapeutics
517.13
153.48
42.21%
ASND
Ascendis Pharma
199.99
60.29
43.16%
GMAB
Genmab
32.38
11.62
55.97%
BNTX
BioNTech SE
92.50
-21.01
-18.51%

Royalty Pharma Corporate Events

Private Placements and FinancingBusiness Operations and Strategy
Royalty Pharma Completes $2 Billion Senior Notes Offering
Positive
Sep 16, 2025

On September 16, 2025, Royalty Pharma plc successfully completed its offering of senior notes totaling $2 billion, consisting of $600 million in 4.450% Senior Notes due 2031, $900 million in 5.200% Senior Notes due 2035, and $500 million in 5.950% Senior Notes due 2055. This financial maneuver, backed by senior unsecured guarantees, is part of a strategic move to strengthen the company’s capital structure and potentially enhance its market position. The offering, governed by an underwriting agreement established on September 2, 2025, includes standard terms for such financial instruments and highlights Royalty Pharma’s proactive approach in managing its financial obligations.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 09, 2025