Efficacy DifferentiationThere is no clear safety and efficacy differentiation between Zanza and Cabo, though the data set is limited.
Regulatory ChallengesThe FDA announced an ADCOM for the cabozantinib review in neuroendocrine tumors due to uncertainties in the study outcomes.
Safety ConcernsSafety concerns, including serious adverse events, are likely to be discussed during the cabozantinib ADCOM.