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Moderna (MRNA)
NASDAQ:MRNA
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Moderna (MRNA) AI Stock Analysis

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MRNA

Moderna

(NASDAQ:MRNA)

Rating:55Neutral
Price Target:
$35.00
▲(2.49%Upside)
Moderna's financial performance is the most significant factor affecting its stock score, with substantial declines in revenue and profitability. Technical indicators provide some positive momentum, but valuation remains weak due to negative earnings. Despite strategic cost reductions and market expansions, challenges persist, particularly in revenue generation and regulatory hurdles.
Positive Factors
Clinical Trial Results
Moderna reported positive results from the Phase III P304 study investigating the relative vaccine efficacy (rVE) of its seasonal flu mRNA vaccine (mRNA-1010) in adults >50 years old.
Regulatory Approvals
Regulatory filings for the flu and flu+COVID combination vaccine (mRNA-1083) will be submitted shortly, highlighting a significant commercial opportunity.
Vaccine Efficacy
MRNA-1010 achieves superior vaccine efficacy to Fluarix in Phase III study, opening up regulatory path for a combination flu/COVID vaccine.
Negative Factors
Market Skepticism
Positioning in the stock skews short, indicating some market skepticism.
Regulatory Challenges
A more onerous vaccine regulatory environment is weighing not just on approvability and recommended use of Moderna's vaccines, but also on operating expenses.
Revenue Estimates
Lower expected COVID-19 revenue has led to a slight reduction in total revenue estimates.

Moderna (MRNA) vs. SPDR S&P 500 ETF (SPY)

Moderna Business Overview & Revenue Model

Company DescriptionModerna, Inc. is a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines to create a new generation of transformative medicines for patients. The company is involved in the development and commercialization of mRNA-based vaccines and therapeutics across various therapeutic areas, including infectious diseases, oncology, cardiovascular diseases, and rare genetic disorders. Moderna's most notable product is its COVID-19 vaccine, which has played a significant role in addressing the global pandemic.
How the Company Makes MoneyModerna makes money primarily through the sale of its mRNA-based COVID-19 vaccine, which became a major source of revenue following its emergency use authorization and subsequent full approval in numerous countries worldwide. The company enters into supply agreements with governments and international organizations to distribute its vaccines. Additionally, Moderna is exploring and developing other therapeutic and vaccine candidates, aiming to expand its product portfolio. Revenue also comes from collaborations and partnerships with other pharmaceutical and biotech companies, research grants, and government contracts that support the development of its pipeline products. These partnerships often involve significant upfront payments, milestone payments, and royalties on future product sales, contributing to the company's earnings.

Moderna Key Performance Indicators (KPIs)

Any
Any
Product Sales by Geography
Product Sales by Geography
Shows where Moderna's products are selling the most, highlighting regional strengths and potential vulnerabilities due to local market conditions or regulatory environments.
Chart InsightsModerna's product sales have experienced significant volatility across geographies, with a notable decline in Europe and the Rest of World regions in recent quarters. The U.S. market showed a temporary rebound in late 2024 but remains inconsistent. The earnings call highlights a strategic focus on cost reduction and market expansion, yet the company faces challenges with declining revenues and a net loss. Despite these hurdles, Moderna's strong cash position and expansion in oncology and international vaccine markets suggest a potential for long-term growth.
Data provided by:Main Street Data

Moderna Earnings Call Summary

Earnings Call Date:May 01, 2025
(Q1-2025)
|
% Change Since: 19.66%|
Next Earnings Date:Aug 01, 2025
Earnings Call Sentiment Neutral
Moderna has made significant progress in cost reduction and market expansion, particularly in the oncology and international vaccine markets. However, the company still faces challenges with declining revenues, significant net losses, and extended regulatory review timelines for key products.
Q1-2025 Updates
Positive Updates
Cost Reduction Achievements
Moderna achieved a 19% reduction in combined R&D, SG&A, and cost of sales compared to Q1 2024. This marks the third consecutive quarter of double-digit year-over-year declines in these expenses.
Expansion of Commercial Markets
Moderna expanded its commercial reach by receiving approvals for its mRESVIA vaccine in Australia, Taiwan, the UK, and Switzerland, in addition to previous approvals in the US, EU, and Canada.
Oncology Portfolio Expansion
Moderna announced the expansion of its oncology portfolio with the addition of the Checkpoint medicine program, showing early but encouraging data.
Strong Cash Position
Moderna ended Q1 2025 with $8.4 billion in cash and investments, maintaining a strong financial position despite a net loss for the quarter.
Negative Updates
Significant Revenue Decline
Total revenue for Q1 2025 was $108 million, reflecting a 35% decrease year-over-year, attributed to the seasonal nature of the respiratory vaccines and lower vaccination rates.
Net Loss for the Quarter
Moderna reported a net loss of $1 billion for Q1 2025, an improvement from a $1.2 billion loss in Q1 2024, but still a significant negative financial result.
COVID Vaccine Sales Decline
Net product sales were $86 million, primarily driven by COVID vaccine sales. This was a decline from the previous year due to the transition of COVID into routine seasonal vaccination patterns.
Extended Review Timeline for Flu COVID Combination Vaccine
The FDA now requires flu vaccine efficacy data to support the application for the flu COVID combination vaccine, extending the review timeline into 2026.
Company Guidance
During the Moderna first quarter 2025 conference call, the company provided detailed guidance on various financial and operational metrics. For Q1 2025, Moderna reported revenues of $0.1 billion with a net loss of $1 billion, aligning with their expectations due to the seasonal nature of their respiratory vaccine business. They ended the quarter with $8.4 billion in cash and investments. Moderna achieved a 19% reduction in combined cost of sales, R&D, and SG&A expenses compared to Q1 2024. Net product sales were $86 million, mainly from COVID vaccine sales, with the U.S. contributing about one-third of these sales. The company expects total revenue for 2025 to range between $1.5 billion and $2.5 billion, with projected cost of sales at approximately $1.2 billion. R&D expenses are anticipated to be $4.1 billion for the year, while SG&A expenses are expected to be around $1.1 billion. Looking ahead, Moderna plans to drive $1.4 billion to $1.7 billion in cost reductions by 2027, aiming for a cash cost of $4.2 billion that year. The company continues to focus on expanding its product portfolio, with advancements in its oncology pipeline and ongoing late-stage trials for several vaccines.

Moderna Financial Statement Overview

Summary
Moderna faces significant financial challenges with declining revenue and profitability. Operational losses and negative cash flows pose risks to financial stability despite a strong equity base and low leverage.
Income Statement
45
Neutral
Moderna's income statement shows a significant decline in revenue from 2022 to TTM (Trailing-Twelve-Months) 2025, with revenue dropping from $19.26 billion to $3.16 billion. Both EBIT and net income have turned negative, indicating substantial operational losses. The gross profit margin has also decreased sharply. These trends suggest substantial challenges in maintaining profitability and revenue growth.
Balance Sheet
55
Neutral
The balance sheet indicates a strong equity position with stockholders' equity consistently making up a large portion of total assets. However, the recent increase in total liabilities and the decrease in total assets since 2021 suggest a weakening financial position. The debt-to-equity ratio remains low, and the company has maintained a positive net cash position, reducing immediate financial risk.
Cash Flow
40
Negative
Moderna's cash flow statement shows a concerning trend with negative operating cash flow and declining free cash flow. The free cash flow has deteriorated from a strong positive in 2022 to a negative in TTM 2025. The operating cash flow to net income ratio and free cash flow to net income ratio reflect operational inefficiencies and cash management challenges.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue3.24B6.85B19.26B17.74B274.49M
Gross Profit1.77B2.15B13.85B15.12B266.56M
EBITDA-3.39B-3.28B9.77B13.53B-732.00M
Net Income-3.56B-4.71B8.36B12.20B-747.06M
Balance Sheet
Total Assets14.14B18.43B25.86B24.67B7.34B
Cash, Cash Equivalents and Short-Term Investments7.03B8.60B9.90B10.73B4.61B
Total Debt747.00M1.24B1.20B916.00M237.00M
Total Liabilities3.24B4.57B6.74B10.52B4.78B
Stockholders Equity10.90B13.85B19.12B14.14B2.56B
Cash Flow
Free Cash Flow-4.05B-3.83B4.58B13.34B1.96B
Operating Cash Flow-3.00B-3.12B4.98B13.62B2.03B
Investing Cash Flow1.95B4.21B-5.18B-8.52B-1.67B
Financing Cash Flow56.00M-1.38B-3.45B-873.00M2.03B

Moderna Technical Analysis

Technical Analysis Sentiment
Positive
Last Price34.15
Price Trends
50DMA
28.58
Positive
100DMA
28.79
Positive
200DMA
35.76
Negative
Market Momentum
MACD
1.53
Negative
RSI
64.57
Neutral
STOCH
72.12
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MRNA, the sentiment is Positive. The current price of 34.15 is above the 20-day moving average (MA) of 31.69, above the 50-day MA of 28.58, and below the 200-day MA of 35.76, indicating a neutral trend. The MACD of 1.53 indicates Negative momentum. The RSI at 64.57 is Neutral, neither overbought nor oversold. The STOCH value of 72.12 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MRNA.

Moderna Risk Analysis

Moderna disclosed 73 risk factors in its most recent earnings report. Moderna reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Moderna Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
84
Outperform
$12.44B20.6930.22%24.49%244.87%
78
Outperform
$13.73B12.1519.94%19.85%21.16%
77
Outperform
$11.32B21.909.64%17.99%152.10%
73
Outperform
$13.64B217.200.47%17.13%-88.78%
72
Outperform
$14.43B13.1422.69%25.11%46.46%
55
Neutral
$13.21B-29.34%-38.25%44.29%
52
Neutral
$7.63B0.11-62.96%2.08%16.16%0.31%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MRNA
Moderna
34.15
-88.02
-72.05%
BMRN
BioMarin Pharmaceutical
59.01
-25.06
-29.81%
EXEL
Exelixis
45.60
22.49
97.32%
INCY
Incyte
70.20
1.61
2.35%
UTHR
United Therapeutics
304.50
-30.77
-9.18%
GMAB
Genmab
23.40
-5.08
-17.84%

Moderna Corporate Events

Business Operations and StrategyFinancial Disclosures
Moderna Projects Revenue Growth and Strategic Cost Reduction
Positive
Jan 13, 2025

Moderna announced its 2024 product sales reached $3.0 to 3.1 billion, driven by its COVID-19 vaccine business, and reported a cash balance of approximately $9.5 billion. Looking ahead, the company plans to reduce cash costs by $1 billion in 2025 and anticipates further cost reductions in 2026. The company expects revenues of $1.5 to 2.5 billion in 2025 and aims for several product approvals and data readouts across its prioritized programs, including vaccines for respiratory viruses and other diseases, with potential significant financial and industry impact.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 11, 2025