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OZEM - ETF AI Analysis

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OZEM

Roundhill GLP-1 & Weight Loss ETF (OZEM)

Rating:55Neutral
Price Target:
OZEM, the Roundhill GLP-1 & Weight Loss ETF, has a solid overall rating that reflects a mix of strong, established drug makers and more speculative biotech names. Major holdings like Novo Nordisk, Eli Lilly, Pfizer, Chugai, and Amgen support the fund’s quality through strong financial performance, positive earnings outlooks, and generally favorable technical trends, even if some face valuation concerns or short-term challenges. The main risk is that several holdings are in the same pharmaceutical and biotech space, and early-stage companies like Viking Therapeutics add volatility due to high losses and cash burn.
Positive Factors
Focused Exposure to Weight-Loss Theme
The ETF targets companies involved in GLP-1 and weight-loss treatments, giving investors direct exposure to a fast-growing area of health care.
Strong Performance From Key Holdings
Several major positions like Eli Lilly, Viking Therapeutics, CSPC Pharmaceutical Group, and Amgen have shown strong gains, helping support the fund’s recent results.
Global Health Care Diversification
Holdings spread across the U.S., Hong Kong, and Japan within health care reduce reliance on any single country’s regulatory or market environment.
Negative Factors
High Sector Concentration in Health Care
With most assets in health care, the fund is heavily exposed to industry-specific risks such as drug trial setbacks and regulatory changes.
Notable Underperforming Holdings
Some sizable positions like Kailera Therapeutics, Chugai Pharmaceutical, and Ascletis Pharma have shown weak performance, which can drag on overall returns.
Above-Average Expense Ratio
The fund’s relatively high fee means more of the returns go to costs, which can be a bigger concern if performance remains weak over time.

OZEM vs. SPDR S&P 500 ETF (SPY)

OZEM Summary

Roundhill GLP-1 & Weight Loss ETF (OZEM) focuses on companies working on weight-loss drugs and treatments, especially GLP-1 medicines used for obesity and related health issues. It doesn’t track a traditional index, but instead targets a specific theme in healthcare and biotech. The fund holds major drug makers like Novo Nordisk and Eli Lilly, along with smaller biotech firms, giving investors a mix of established names and potential up-and-comers. Someone might invest for long-term growth tied to rising demand for weight-loss treatments. A key risk is that it’s heavily concentrated in healthcare and can swing sharply with drug trial results, regulation, and market sentiment.
How much will it cost me?The Roundhill GLP-1 & Weight Loss ETF (OZEM) has an expense ratio of 0.59%, meaning you’ll pay $5.90 per year for every $1,000 invested. This is higher than average because it is actively managed, focusing on a niche sector like pharmaceuticals and biotechnology, which requires more research and specialized management.
What would affect this ETF?The Roundhill GLP-1 & Weight Loss ETF could benefit from growing global demand for innovative health solutions, particularly in obesity and metabolic disorder treatments, as well as advancements in biotechnology and pharmaceuticals led by top holdings like Novo Nordisk and Eli Lilly. However, potential risks include regulatory hurdles, competition in the weight management sector, and broader economic challenges that may impact healthcare spending or innovation funding. Global exposure also means the ETF could be affected by geopolitical events or currency fluctuations.

OZEM Top 10 Holdings

OZEM is heavily anchored in a handful of GLP-1 powerhouses, with Novo Nordisk and Eli Lilly steering the ship as their shares keep rising over the past few months, giving the fund a strong core in obesity and diabetes treatments. Amgen and CSPC Pharmaceutical add more fuel to the rally with steady-to-rising momentum, while Pfizer is more of a steady plodder, not really hurting but not helping much either. On the flip side, Viking Therapeutics and especially Kailera look like weak links, dragging at the fund’s heels. Overall, this is a highly concentrated, globally diversified bet on weight-loss and metabolic health, but very much tied to a small group of big drug names.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Novo Nordisk13.82%$8.72M$230.83B9.64%
73
Outperform
Eli Lilly & Co12.67%$7.99M$1.14T56.06%
72
Outperform
Pfizer6.61%$4.17M$143.34B6.96%
74
Outperform
CSPC Pharmaceutical Group6.60%$4.16MHK$100.77B-7.76%
63
Neutral
Viking Therapeutics4.97%$3.14M$3.88B1.66%
53
Neutral
Kailera Therapeutics, Inc.4.72%$2.97M$2.19B
Chugai Pharmaceutical Co4.14%$2.61M¥11.63T-8.69%
74
Outperform
Amgen4.08%$2.57M$209.21B31.36%
77
Outperform
4.07%$2.57M
Ascletis Pharma, Inc.3.48%$2.19MHK$9.31B-18.66%
54
Neutral

OZEM Technical Analysis

Technical Analysis Sentiment
Negative
Last Price
Price Trends
50DMA
31.76
Negative
100DMA
31.51
Positive
200DMA
32.21
Negative
Market Momentum
MACD
RSI
STOCH
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For OZEM, the sentiment is Negative. The current price of undefined is equal to the 20-day moving average (MA) of 32.74, equal to the 50-day MA of 31.76, and equal to the 200-day MA of 32.21, indicating a bearish trend. The MACD of ― indicates undefined momentum. The RSI at ― is undefined, neither overbought nor oversold. The STOCH value of ― is undefined, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OZEM.

OZEM Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$62.58M0.59%
55
Neutral
$55.50M0.75%
66
Neutral
$48.31M1.00%
47
Neutral
$46.24M0.50%
58
Neutral
$42.28M0.80%
62
Neutral
$26.91M0.44%
64
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OZEM
Roundhill GLP-1 & Weight Loss ETF
31.75
7.51
30.98%
HRTS
Tema Cardiovascular and Metabolic ETF
PSIL
AdvisorShares Psychedelics ETF
FMED
Fidelity Disruptive Medicine ETF
MEDI
Harbor Health Care ETF
TMED
T. Rowe Price Health Care ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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