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OZEM - ETF AI Analysis

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OZEM

Roundhill GLP-1 & Weight Loss ETF (OZEM)

Rating:60Neutral
Price Target:
OZEM, the Roundhill GLP-1 & Weight Loss ETF, has a solid overall rating driven mainly by large positions in leaders like Eli Lilly, Novo Nordisk, AstraZeneca, Amgen, Pfizer, and Roche, which all benefit from strong financial performance, important drug pipelines, and generally positive long-term outlooks. The rating is held back somewhat by earlier-stage or less profitable biotech names such as Viking Therapeutics, Innovent Biologics, and Ascletis Pharma, which face losses, cash flow challenges, and valuation concerns. The main risk factor is the fund’s concentration in a single, specialized area of healthcare (weight-loss and related biotech), which can make performance more volatile if sentiment or regulation in this niche shifts.
Positive Factors
Targeted Exposure to GLP-1 and Weight-Loss Theme
The ETF focuses on companies tied to GLP-1 and weight-loss treatments, giving investors direct access to a fast-growing area of health care.
Several Strong Recent Performers in Top Holdings
Some key positions, such as Pfizer, Innovent Biologics, Ascletis Pharma, Amgen, and AstraZeneca, have shown strong or steady performance, helping support the fund despite weakness in other names.
Global Mix with U.S. and Asia Exposure
Holdings spread across the U.S., Hong Kong, and Japan provide some geographic diversification within the health care theme.
Negative Factors
Heavy Concentration in Health Care
With almost all assets in the health care sector, the fund is highly sensitive to news, regulation, and sentiment affecting drug and biotech companies.
Recent Overall Performance Has Been Weak
The ETF has delivered weak returns over the year-to-date and three-month periods, showing that the theme has struggled recently.
High Weight in Lagging Mega-Cap Leaders
Large positions in Eli Lilly and Novo Nordisk have recently lagged, which can drag on the fund’s results given their sizable share of the portfolio.

OZEM vs. SPDR S&P 500 ETF (SPY)

OZEM Summary

The Roundhill GLP-1 & Weight Loss ETF (OZEM) focuses on companies working on weight-loss drugs and treatments, especially GLP-1 medicines used for obesity and related health issues. It doesn’t track a traditional index, but instead targets a theme in health care, mainly pharma and biotech firms in the U.S. and abroad. Well-known holdings include Eli Lilly and Novo Nordisk, both leaders in modern weight-loss drugs. Someone might invest for growth potential as demand for obesity treatments rises. A key risk is that it’s heavily concentrated in health care and drug makers, so it can be very volatile and move sharply with news about these medicines.
How much will it cost me?The Roundhill GLP-1 & Weight Loss ETF (OZEM) has an expense ratio of 0.59%, meaning you’ll pay $5.90 per year for every $1,000 invested. This is higher than average because it is actively managed, focusing on a niche sector like pharmaceuticals and biotechnology, which requires more research and specialized management.
What would affect this ETF?The Roundhill GLP-1 & Weight Loss ETF could benefit from growing global demand for innovative health solutions, particularly in obesity and metabolic disorder treatments, as well as advancements in biotechnology and pharmaceuticals led by top holdings like Novo Nordisk and Eli Lilly. However, potential risks include regulatory hurdles, competition in the weight management sector, and broader economic challenges that may impact healthcare spending or innovation funding. Global exposure also means the ETF could be affected by geopolitical events or currency fluctuations.

OZEM Top 10 Holdings

OZEM is heavily tilted toward a handful of GLP-1 powerhouses, with Eli Lilly and Novo Nordisk still setting the tone even as their shares have been losing steam lately, which can weigh on the fund. Offsetting that, steadier names like Pfizer and AstraZeneca have been quietly rising, adding some ballast. On the higher-risk side, Viking Therapeutics is showing mixed momentum, while Chinese players like Innovent Biologics and Ascletis Pharma are sprinting ahead, injecting volatility. Overall, this is a concentrated, globally diversified bet on obesity and metabolic health drugs.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Eli Lilly & Co15.28%$7.96M$835.18B-1.03%
72
Outperform
Novo Nordisk14.53%$7.57M$181.09B-34.21%
73
Outperform
Pfizer7.18%$3.74M$153.59B16.22%
74
Outperform
Ascletis Pharma, Inc.5.32%$2.77MHK$20.32B189.80%
54
Neutral
Viking Therapeutics5.25%$2.74M$3.80B27.16%
53
Neutral
Innovent Biologics5.10%$2.66MHK$148.88B72.22%
61
Neutral
Roche Holding AG4.05%$2.11M$327.04B22.13%
73
Outperform
Amgen3.81%$1.99M$185.95B20.17%
77
Outperform
3.71%$1.93M
AstraZeneca3.58%$1.86M$292.69B32.74%
80
Outperform

OZEM Technical Analysis

Technical Analysis Sentiment
Negative
Last Price
Price Trends
50DMA
31.93
Negative
100DMA
33.43
Negative
200DMA
30.36
Negative
Market Momentum
MACD
-0.31
Positive
RSI
32.97
Neutral
STOCH
4.91
Positive
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For OZEM, the sentiment is Negative. The current price of undefined is equal to the 20-day moving average (MA) of 31.53, equal to the 50-day MA of 31.93, and equal to the 200-day MA of 30.36, indicating a bearish trend. The MACD of -0.31 indicates Positive momentum. The RSI at 32.97 is Neutral, neither overbought nor oversold. The STOCH value of 4.91 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OZEM.

OZEM Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$51.20M0.59%
60
Neutral
$58.63M0.50%
58
Neutral
$50.33M0.75%
67
Neutral
$32.27M1.00%
45
Neutral
$27.42M0.80%
62
Neutral
$21.00M0.75%
70
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OZEM
Roundhill GLP-1 & Weight Loss ETF
29.92
5.49
22.47%
FMED
Fidelity Disruptive Medicine ETF
HRTS
Tema Cardiovascular and Metabolic ETF
PSIL
AdvisorShares Psychedelics ETF
MEDI
Harbor Health Care ETF
GDOC
Goldman Sachs Future Health Care Equity ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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