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Chugai Pharmaceutical Co Ltd (JP:4519)
:4519
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Chugai Pharmaceutical Co (4519) AI Stock Analysis

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JP:4519

Chugai Pharmaceutical Co

(OTC:4519)

Rating:70Outperform
Price Target:
¥6,701.00
▲(10.00% Upside)
Chugai Pharmaceutical's strong financial performance and positive earnings call sentiment are significant strengths. However, the bearish technical indicators and moderate valuation slightly offset these positives, resulting in a balanced overall score.

Chugai Pharmaceutical Co (4519) vs. iShares MSCI Japan ETF (EWJ)

Chugai Pharmaceutical Co Business Overview & Revenue Model

Company DescriptionChugai Pharmaceutical Co., Ltd., together with its subsidiaries, engages in the research, development, manufacturing, sale, importation, and exportation of pharmaceuticals in Japan and internationally. The company's products for oncology primarily include Avastin, Tecentriq, Perjeta, Alecensa, Herceptin, Kadcyla, Rituxan, Gazyva, and Xeloda; osteoporosis, including Actemra, Edirol, and Bonviva; renal diseases consist of Mircera and Oxarol; and neurology/other diseases comprise Hemlibra, CellCept, and Enspryng. It has various development product candidates in the areas of oncology, bone and joint diseases, autoimmune diseases, renal diseases, neurology, and other diseases. Chugai Pharmaceutical Co., Ltd. has strategic alliances with Roche Group; and collaboration and joint research with academia. The company was founded in 1925 and is headquartered in Tokyo, Japan. Chugai Pharmaceutical Co., Ltd. is a subsidiary of Roche Holding Ltd.
How the Company Makes MoneyChugai Pharmaceutical generates revenue primarily through the sales of its proprietary pharmaceutical products, particularly in oncology and other specialty therapeutic areas. A significant portion of its income comes from the commercialization of its innovative drugs, including those developed internally and through partnerships. The company has strategic collaborations with Roche, its largest shareholder, which allows for shared research and development costs, as well as access to international markets. Additionally, Chugai earns revenue through licensing agreements and royalties from its patented drug technologies. The company also invests in research to expand its pipeline of new therapies, further enhancing its future revenue potential.

Chugai Pharmaceutical Co Earnings Call Summary

Earnings Call Date:Jul 24, 2025
(Q2-2025)
|
% Change Since: -14.40%|
Next Earnings Date:Oct 24, 2025
Earnings Call Sentiment Neutral
The earnings call reveals a mix of positive and negative outcomes. Revenue and profit increased, driven by strong product performance and strategic investments. However, challenges such as the impact of drug price revisions, project suspensions, and revenue recognition delays were also highlighted. The overall sentiment is balanced with notable achievements and significant challenges.
Q2-2025 Updates
Positive Updates
Increased Revenue and Profit
In the second quarter of 2025, domestic and overseas product sales increased, resulting in a 4.6% increase in revenue, a 3.5% increase in operating profit, and a 2.1% increase in net income compared to the previous year.
Strong Performance of New Products
Sales of new products such as Phesgo, PiaSky, and Vabysmo increased by JPY 6.1 billion domestically. Overseas sales also saw a significant increase of JPY 19.7 billion, with exports of Actemra to Roche increasing significantly.
R&D Milestone Achievements
Eli Lilly announced the success of a global Phase III trial for orforglipron for type 2 diabetes. New in-house projects, MINT91 and medium molecule project AUBE00, have begun Phase I trials.
New Investments in Pharmaceutical Manufacturing
A new research building UKX at the Ukima site with a total investment of JPY 80 billion was announced to strengthen pharmaceutical manufacturing process development functions.
Negative Updates
Impact of NHI Drug Price Revisions
Domestic sales were negatively impacted by NHI drug price revisions and the penetration of generics.
Suspension of In-house Development Projects
The company decided to discontinue in-house development of 5 early-stage pipeline projects based on prioritization.
Delays in Revenue Recognition
A significant amount of Hemlibra revenue (JPY 38 billion) scheduled for June was delayed to July due to delivery procedure delays.
Challenges with LUNA18 Development
Concerns over the therapeutic window and competitive advantage led to the suspension of LUNA18 development in favor of focusing on AUBE00.
Company Guidance
During the earnings call for the second quarter of fiscal year 2025, several key financial metrics were highlighted. Revenue increased by 4.6% compared to the previous year, reaching JPY 578.5 billion, driven by both domestic and overseas product sales. Operating profit rose by 3.5% to JPY 272 billion, and net income saw a 2.1% increase, totaling JPY 193.5 billion. The company noted a JPY 25.6 billion rise in revenue, with domestic sales growing by JPY 6.1 billion despite challenges like NHI drug price revisions. Overseas sales were boosted by JPY 19.7 billion due to increased export volumes and favorable exchange rates. The call also covered strategic R&D developments, including progress on projects such as orforglipron and NXT007, while announcing the discontinuation of five early-stage in-house pipeline projects to prioritize resources for higher-value endeavors. Additionally, a new JPY 80 billion research building was announced, aimed at strengthening pharmaceutical manufacturing capabilities.

Chugai Pharmaceutical Co Financial Statement Overview

Summary
Chugai Pharmaceutical demonstrates strong financial health with consistent revenue growth, high profitability margins, and stable cash flow. The low leverage and impressive return on equity enhance its financial resilience, despite a slight decrease in free cash flow.
Income Statement
88
Very Positive
Chugai Pharmaceutical shows robust financial performance with a strong revenue growth trend over the years. The TTM figures reflect a gross profit margin of 71% and a net profit margin of 33.6%, indicating efficient cost management and profitability. The company achieved a 9.9% revenue growth rate compared to the previous period, demonstrating solid business expansion. EBIT and EBITDA margins of 47.7% and 49.4%, respectively, highlight strong operational efficiency.
Balance Sheet
81
Very Positive
The balance sheet reveals strong financial stability with a low debt-to-equity ratio of 0.007, showcasing minimal leverage risk. The return on equity is impressive at 21.5%, reflecting effective use of shareholder funds. The equity ratio stands at 89.1%, indicating a solid capital structure primarily financed through equity, reducing financial risk.
Cash Flow
85
Very Positive
Chugai Pharmaceutical's cash flow statement reflects a positive cash flow trajectory, with a free cash flow growth rate of -10.9%, indicating slight decreases in free cash flows over the recent periods. However, the operating cash flow to net income ratio remains strong at 1.01, demonstrating sufficient cash generation relative to profits. The free cash flow to net income ratio of 0.86 supports the company's ability to fund operations and investments without reliance on external financing.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.22T1.17T1.11T1.26T999.76B786.95B
Gross Profit866.37B831.20B698.06B783.70B661.61B513.48B
EBITDA603.35B568.39B475.64B562.66B450.30B328.72B
Net Income410.19B387.32B325.47B374.43B303.00B214.73B
Balance Sheet
Total Assets2.14T2.21T1.93T1.87T1.54T1.24T
Cash, Cash Equivalents and Short-Term Investments944.55B996.35B738.98B503.11B471.97B378.62B
Total Debt13.09B10.90B13.46B14.11B16.04B11.28B
Total Liabilities232.26B306.87B306.97B445.37B350.68B255.50B
Stockholders Equity1.91T1.90T1.63T1.42T1.19T980.00B
Cash Flow
Free Cash Flow353.18B396.68B335.67B172.87B206.76B143.62B
Operating Cash Flow415.36B447.60B409.93B244.11B279.63B205.03B
Investing Cash Flow-284.05B-227.37B-37.29B-145.99B-118.93B-98.31B
Financing Cash Flow-169.46B-141.01B-139.33B-145.64B-107.41B-99.50B

Chugai Pharmaceutical Co Technical Analysis

Technical Analysis Sentiment
Negative
Last Price6092.00
Price Trends
50DMA
7221.02
Negative
100DMA
7235.97
Negative
200DMA
7012.30
Negative
Market Momentum
MACD
-37.90
Positive
RSI
25.44
Positive
STOCH
49.77
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4519, the sentiment is Negative. The current price of 6092 is below the 20-day moving average (MA) of 7112.35, below the 50-day MA of 7221.02, and below the 200-day MA of 7012.30, indicating a bearish trend. The MACD of -37.90 indicates Positive momentum. The RSI at 25.44 is Positive, neither overbought nor oversold. The STOCH value of 49.77 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4519.

Chugai Pharmaceutical Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$12.19T30.8521.48%1.76%10.29%11.37%
51
Neutral
$7.38B-0.04-62.85%2.34%15.18%-2.87%
$19.70B35.195.46%4.55%
$46.30B23.0518.32%1.70%
$9.29B34.814.61%2.23%
$15.69B11.9313.71%4.84%
$45.78B47.631.99%4.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4519
Chugai Pharmaceutical Co
6,092.00
6.20
0.10%
ALPMF
Astellas Pharma
11.10
0.50
4.72%
DSKYF
Daiichi Sankyo Company
23.47
-11.41
-32.71%
KYKOF
Kyowa Kirin Co
17.13
-2.51
-12.78%
SGIOF
Shionogi & Co
16.79
2.83
20.27%
TKPHF
Takeda Pharmaceutical Co
29.00
1.67
6.11%

Chugai Pharmaceutical Co Corporate Events

Chugai Highlights Eli Lilly’s Positive Phase 3 Results for Orforglipron
Aug 7, 2025

Chugai Pharmaceutical Co., Ltd. announced Eli Lilly’s positive Phase 3 trial results for orforglipron, an oral GLP-1 receptor agonist, which showed significant weight reduction in adults with obesity. The trial demonstrated that orforglipron achieved primary and secondary endpoints, with a safety profile consistent with existing GLP-1 medicines. This development is significant for Eli Lilly’s market positioning in weight management solutions, though it does not impact Chugai’s financial forecast for 2025.

The most recent analyst rating on (JP:4519) stock is a Buy with a Yen7650.00 price target. To see the full list of analyst forecasts on Chugai Pharmaceutical Co stock, see the JP:4519 Stock Forecast page.

Chugai Pharmaceutical to Build New Laboratory to Boost R&D and Environmental Goals
Jul 24, 2025

Chugai Pharmaceutical Co. announced plans to construct a new laboratory building, UKX, at its Ukima Site in Tokyo to enhance its manufacturing process development capabilities and advance environmental initiatives. This strategic move is part of Chugai’s growth strategy, TOP I 2030, aiming to double R&D output and achieve early proof of concept in clinical development. The new facility will support rapid clinical trial entry and innovation in drug manufacturing processes, particularly for mid-size molecules. Additionally, the environmentally friendly design of UKX aligns with Chugai’s Mid-Term Environmental Goals 2030, focusing on reducing CO2 emissions and phasing out halogenated hydrocarbons. This investment is not expected to impact the company’s financial forecast for 2025.

The most recent analyst rating on (JP:4519) stock is a Buy with a Yen7650.00 price target. To see the full list of analyst forecasts on Chugai Pharmaceutical Co stock, see the JP:4519 Stock Forecast page.

Chugai Pharmaceutical Reports Strong H1 2025 Results and Announces Special Dividend
Jul 24, 2025

Chugai Pharmaceutical Co. reported a strong financial performance for the first half of 2025, with significant increases in revenue, operating profit, and net income compared to the previous year. The company announced a special dividend to celebrate its 100th anniversary, highlighting its robust financial health and commitment to rewarding shareholders. This announcement underscores Chugai’s solid market position and its strategic focus on sustainable growth, which is likely to have positive implications for its stakeholders.

The most recent analyst rating on (JP:4519) stock is a Buy with a Yen7650.00 price target. To see the full list of analyst forecasts on Chugai Pharmaceutical Co stock, see the JP:4519 Stock Forecast page.

Chugai Pharmaceutical’s Performance Highlighted in Roche’s Half-Year Results
Jul 24, 2025

Chugai Pharmaceutical Co., Ltd., a key player in the pharmaceutical industry, is significantly influenced by its parent company, Roche Holding Ltd, which owns a majority of its shares. The recent announcement of Roche’s half-year results for 2025 includes Chugai’s performance, highlighting the integrated financial outcomes and strategic alignment between the two companies. This announcement underscores the operational synergy and market positioning of Chugai within the Roche Group, potentially impacting stakeholders by showcasing the company’s performance and strategic direction.

The most recent analyst rating on (JP:4519) stock is a Buy with a Yen7650.00 price target. To see the full list of analyst forecasts on Chugai Pharmaceutical Co stock, see the JP:4519 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 09, 2025