Record financial results for FY2025
Revenue JPY 1,257.9 billion (exceeded initial forecast by 5.7%; Taniguchi reported +7.5% year-on-year), core operating profit JPY 623.2 billion (+12.1% YoY), operating profit margin a record 49.5%, and net income JPY 451.0 billion (+13.6% YoY).
Strong FY2026 guidance
Management projects FY2026 revenue JPY 1,345 billion (+6.9% YoY) and core operating profit JPY 670 billion (+7.5% YoY), supported by domestic product sales growth, higher royalty/profit-share income and milestone payments.
Dividend increase and shareholder returns
FY2025 total annual dividend JPY 272 per share (year-end JPY 147 including JPY 75 100th-anniversary commemorative dividend). FY2026 ordinary dividend forecast raised by JPY 10 to JPY 132; policy targets an average payout ratio of 45% based on core EPS.
Robust product sales and export performance
Pharmaceutical product sales JPY 1,077.8 billion (+8.0% YoY). Overseas pharmaceutical sales JPY 605.4 billion (+12.8% YoY), driven by strong exports of Hemlibra and Actemra; Hemlibra full-year exports ~JPY 20 billion above initial forecast and Actemra exceeded forecast by ~JPY 30 billion due to slower-than-expected biosimilar penetration.
Pipeline progress and clinical successes
Proof of concept (POC) confirmed for NXT007 and advanced to Phase III; Elevidys regulatory approval obtained; Enspryng Phase III met primary endpoint for MOGAD; orforglipron met primary endpoint in switching trial. Giredestrant clinical data: evERA showed PFS risk reduction of 62% (ESR1+ group) and 44% (ITT); lidERA interim analysis showed IDFS risk reduction of 30%.
Pipeline scale and prioritization
Pipeline streamlined for focus: Phase I projects reduced from 21 to 15 to concentrate resources; currently 9 projects in Phase II, 28 in Phase III, and 3 projects under regulatory review with approvals expected within the year.
Operational efficiency and cost control
Cost of sales increased 4.0% but pharmaceutical cost ratio improved by 1.3 percentage points to 32.6%; SG&A expenses held nearly flat at JPY 103.2 billion through efficiency efforts.
Positive capital efficiency and cash generation
Operating cash flow JPY 452.1 billion; ROIC 43.9% (up 1 percentage point YoY) and ROE 22.1%, both well above cost of capital; foreign exchange tailwind added approximately JPY 49.6 billion to revenue and JPY 44.2 billion to operating profit in FY2025.
Open innovation and global partnering expansion
12 new research and technical collaborations closed; new U.S. Partnering Office opened in South San Francisco to accelerate collaborations with academia and bioventures; strategic partnerships announced with Gero, Araris and Rani Therapeutics.