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Shionogi & Co (JP:4507)
:4507

Shionogi & Co (4507) AI Stock Analysis

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JP:4507

Shionogi & Co

(OTC:4507)

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Outperform 75 (OpenAI - 4o)
Rating:75Outperform
Price Target:
¥3,015.00
▲(11.79% Upside)
Shionogi & Co's strong financial performance, characterized by high profitability margins and a solid balance sheet, is the most significant factor driving the score. The technical analysis supports a generally positive trend, while the valuation indicates a fair market price with a decent dividend yield. The absence of earnings call data and corporate events does not impact the score.
Positive Factors
Strong Profitability Margins
High profitability margins indicate efficient cost management and strong pricing power, supporting long-term financial health and competitive positioning.
Solid Balance Sheet
A strong balance sheet with low leverage enhances financial stability and flexibility, allowing the company to invest in growth opportunities.
Efficient Cash Flow Management
Efficient cash flow management ensures the company can fund operations and investments without relying heavily on external financing.
Negative Factors
Decline in Revenue Growth
A decline in revenue growth may signal challenges in market expansion or product demand, potentially affecting future earnings and market position.
Recent Revenue Growth Concerns
Sustained revenue growth is crucial for long-term success; a decline could impact profitability and strategic initiatives if not addressed.
Potential Sales Growth Slowdown
A slowdown in sales growth may hinder the company's ability to capitalize on market opportunities and maintain its competitive edge.

Shionogi & Co (4507) vs. iShares MSCI Japan ETF (EWJ)

Shionogi & Co Business Overview & Revenue Model

Company DescriptionShionogi & Co., Ltd. is a Japanese pharmaceutical company founded in 1878, primarily engaged in the research, development, manufacturing, and marketing of pharmaceuticals. The company operates in various sectors, including prescription pharmaceuticals, over-the-counter (OTC) products, and diagnostic services. Shionogi's core products focus on infectious diseases, pain management, and central nervous system disorders, with a strong emphasis on innovation and the development of new therapies.
How the Company Makes MoneyShionogi generates revenue primarily through the sale of prescription pharmaceuticals, which constitutes the bulk of its income. The company develops proprietary drugs, often investing heavily in research and development to bring new treatments to market. In addition to direct sales, Shionogi engages in partnerships and collaborations with other pharmaceutical companies and research institutions, which can include licensing agreements and joint ventures. These partnerships often provide upfront payments, milestone payments based on development progress, and royalties on sales of partnered products. Furthermore, Shionogi's OTC product lines contribute to its revenue, allowing the company to diversify its income streams. The company's focus on global expansion, particularly in emerging markets, and its commitment to addressing unmet medical needs also play significant roles in driving future earnings.

Shionogi & Co Earnings Call Summary

Earnings Call Date:Jul 28, 2025
(Q1-2025)
|
% Change Since: |
Next Earnings Date:Feb 02, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong financial performance and growth in the HIV business, along with successful M&A activities and advancements in drug development. These positives were tempered by declines in domestic and overseas sales, particularly in China, and concerns regarding R&D cost management. Despite these challenges, the overall outlook remains optimistic due to strategic growth initiatives.
Q1-2025 Updates
Positive Updates
Strong Financial Performance
Revenue for Q1 FY2025 increased to JPY99.8 billion, a rise of JPY2.2 billion compared to the same period last year. Operating profit increased by JPY7 billion to JPY35.1 billion, and profit before tax rose by JPY9.8 billion to JPY46.3 billion. Profit attributable to owners of the parent was JPY39.4 billion, an increase of JPY8.7 billion.
HIV Business Growth
The HIV business showed strong growth, with ViiV's HIV franchise contributing to higher royalty income. Long-acting formulations like Cabenuva and Dovato are driving this growth.
Advancements in Drug Development
Significant progress in the development pipelines, including the filing of Ensitrelvir in Europe and the US. The development of S-365598, a third-generation integrase inhibitor, is ongoing with promising antiviral activity.
Successful M&A Activity
Completion of the tender offer for Torii Pharmaceutical and progress towards merging with the JT Group pharmaceutical business.
Negative Updates
Decline in Domestic and Overseas Business
Domestic prescription drug sales decreased by JPY1.3 billion to JPY14.1 billion, mainly due to reduced sales of drugs for acute respiratory virus infections. Overseas subsidiaries/exports segment also declined by JPY0.7 billion.
Challenges in China
Sales in the China business declined, impacting the overall performance of the overseas segment.
R&D Cost Management Concerns
R&D expenses decreased by JPY4.5 billion due to the completion of multiple large-scale clinical trials, raising concerns about the current level of investment in growth drivers.
Company Guidance
During the first quarter financial results briefing for fiscal year 2025, SHIONOGI reported significant growth in both financial and non-financial metrics. The company achieved a year-over-year increase in revenue to JPY99.8 billion, up by JPY2.2 billion, with operating profit reaching JPY35.1 billion, an increase of JPY7 billion. Profit before tax rose to JPY46.3 billion, up by JPY9.8 billion, and profit attributable to owners of the parent increased by JPY8.7 billion to JPY39.4 billion. EBITDA also saw a rise to JPY40.6 billion, marking a JPY7 billion increase. Significant contributors to this growth included the strong performance of the HIV business, with revenue from this segment driven by ViiV's HIV franchise and royalty income from Roche's Xofluza, which benefited from a flu epidemic in China and the U.S. Non-financial milestones included the completion of a tender offer for Torii Pharmaceutical and progress towards an M&A with the JT Group's pharmaceutical business. The company's strategic focus on pipeline developments, including the filing of Ensitrelvir in Europe and the U.S., is expected to support medium- to long-term growth.

Shionogi & Co Financial Statement Overview

Summary
Shionogi & Co exhibits strong financial health with high profitability, efficient operations, and a stable balance sheet. The company is experiencing significant revenue growth, supported by effective cost management and low financial leverage. While cash flow growth has moderated, the company's cash generation capabilities remain robust. Continued monitoring of cost pressures and debt levels is advisable to maintain financial stability.
Income Statement
85
Very Positive
Shionogi & Co demonstrates strong profitability with a high gross profit margin of 85.54% and a net profit margin of 40.67% for the TTM. The company has shown impressive revenue growth of 50.1% in the TTM, indicating robust expansion. EBIT and EBITDA margins are also healthy at 44.51% and 49.29%, respectively, reflecting efficient operations. However, the slight decline in EBIT margin compared to the previous annual report suggests potential cost pressures.
Balance Sheet
80
Positive
The balance sheet is solid with a low debt-to-equity ratio of 0.0157, indicating minimal leverage and financial risk. Return on equity is strong at 13.32%, showcasing effective use of equity to generate profits. The equity ratio stands at 89.62%, reflecting a stable financial structure with a high proportion of equity financing. However, the slight increase in debt levels over the past year warrants monitoring.
Cash Flow
78
Positive
Cash flow metrics are robust, with a free cash flow to net income ratio of 90.80% and an operating cash flow to net income ratio of 1.73, indicating strong cash generation relative to earnings. Free cash flow growth of 3.36% in the TTM is positive, although it has slowed compared to previous periods. The company's ability to convert income into cash remains a key strength.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue437.26B438.27B435.08B426.68B335.14B297.18B
Gross Profit372.91B370.26B377.48B364.44B279.72B244.65B
EBITDA210.69B230.71B217.81B176.41B143.42B158.67B
Net Income170.84B170.43B162.03B184.97B114.19B111.86B
Balance Sheet
Total Assets1.62T1.54T1.42T1.31T1.15T998.99B
Cash, Cash Equivalents and Short-Term Investments233.86B374.80B358.09B309.22B254.42B276.17B
Total Debt22.70B21.88B11.62B9.41B6.67B7.99B
Total Liabilities176.34B172.85B164.36B189.92B157.32B134.44B
Stockholders Equity1.43T1.36T1.24T1.10T975.66B846.11B
Cash Flow
Free Cash Flow191.81B178.33B126.02B140.68B70.50B76.09B
Operating Cash Flow208.15B195.46B154.28B177.87B102.07B109.04B
Investing Cash Flow-223.58B-129.07B5.92B-48.29B-96.20B-5.26B
Financing Cash Flow-56.33B-51.92B-126.85B-84.12B-36.62B-43.89B

Shionogi & Co Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2697.00
Price Trends
50DMA
2594.05
Positive
100DMA
2580.36
Positive
200DMA
2456.42
Positive
Market Momentum
MACD
20.93
Positive
RSI
51.43
Neutral
STOCH
38.68
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4507, the sentiment is Positive. The current price of 2697 is above the 20-day moving average (MA) of 2691.93, above the 50-day MA of 2594.05, and above the 200-day MA of 2456.42, indicating a neutral trend. The MACD of 20.93 indicates Positive momentum. The RSI at 51.43 is Neutral, neither overbought nor oversold. The STOCH value of 38.68 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4507.

Shionogi & Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
¥290.12B10.429.05%3.59%10.51%9.62%
75
Outperform
¥2.35T13.3312.22%2.32%4.48%11.08%
74
Outperform
$1.28T25.445.75%3.51%6.79%22.14%
73
Outperform
¥305.06B15.457.11%2.51%3.53%38.23%
66
Neutral
$828.16B5.3579.99%29.92%
66
Neutral
¥7.09T207.120.54%4.45%-2.84%-88.29%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4507
Shionogi & Co
2,676.50
557.96
26.34%
JP:4506
Sumitomo Dainippon Pharma Co
2,242.50
1,634.50
268.83%
JP:4523
Eisai Co
4,562.00
360.54
8.58%
JP:4530
Hisamitsu Pharmaceutical Co
4,181.00
69.01
1.68%
JP:4502
Takeda Pharmaceutical Co
4,448.00
518.75
13.20%
JP:4540
Tsumura & Co
3,792.00
-879.25
-18.82%

Shionogi & Co Corporate Events

Shionogi Completes Acquisition of Japan Tobacco’s Pharmaceutical Business
Dec 1, 2025

Shionogi & Co., Ltd. has successfully completed the acquisition of Japan Tobacco Inc.’s pharmaceutical business and the shares of Akros Pharma Inc., enhancing its market presence and operational capabilities in the pharmaceutical industry. This strategic move is expected to strengthen Shionogi’s position in the healthcare market, potentially offering new opportunities for growth and development in its pharmaceutical operations.

Shionogi Announces Corrections to Q2 2025 Financial Results
Nov 28, 2025

Shionogi & Co., Ltd. announced corrections to its Consolidated Financial Results for the second quarter of fiscal year 2025. The corrections involve numerical data related to the number of shares issued and treasury stock, as well as the pro forma information on revenue and profit from a business combination. These adjustments may impact stakeholders’ understanding of the company’s financial performance and projections.

Shionogi & Co. Adopts New Management Policies to Enhance Capital and Stock Awareness
Oct 27, 2025

Shionogi & Co., Ltd. has announced new management policies aimed at enhancing their awareness of capital costs and stock prices, following a Board of Directors meeting. This strategic move is expected to influence the company’s operational focus and potentially impact its market positioning and stakeholder interests.

Shionogi Reports Mixed Q2 FY 2025 Results Amid Revenue Challenges
Oct 27, 2025

Shionogi & Co., Ltd. reported its financial results for the second quarter of FY 2025, showing a slight decrease in revenue by 0.5% to 213 billion yen. The company experienced a decline in prescription drug sales, particularly in the acute respiratory virus infection treatment segment, which saw a 65.1% drop. However, this was partially offset by an increase in royalty income, which rose by 6.4%. The company also noted an increase in sales-related expenses in the U.S. and costs associated with making Torii Pharmaceutical Co., Ltd. a wholly-owned subsidiary. Despite these challenges, Shionogi revised its FY 2025 forecast, indicating a cautious yet optimistic outlook for the remainder of the fiscal year.

Shionogi & Co. Reports Q2 2025 Financial Results and Strategic Expansion
Oct 27, 2025

Shionogi & Co., Ltd. reported its consolidated financial results for the second quarter of fiscal year 2025, showing a slight decrease in revenue and operating profit compared to the same period last year. Despite these declines, the company experienced growth in profit before tax and comprehensive income, indicating a positive financial trajectory. The company also announced a revision in its financial forecast for the year ending March 31, 2026, with expectations of increased revenue and profit. The inclusion of Torii Pharmaceutical Co., Ltd. as a subsidiary marks a strategic expansion in Shionogi’s operations, potentially enhancing its market position and offering new opportunities for growth.

Shionogi & Co. Announces Merger with Shionogi Pharma to Strengthen Supply Chain
Oct 27, 2025

Shionogi & Co., Ltd. has announced a merger with its wholly owned subsidiary, Shionogi Pharma Co., Ltd., effective April 1, 2027. This strategic move aims to enhance the company’s production and supply chain resilience in response to changing geopolitical and regulatory environments, particularly in the infectious disease sector.

Shionogi to Acquire Japan Tobacco’s Pharmaceutical Business
Sep 25, 2025

Shionogi & Co., Ltd. has entered into an absorption-type company split agreement with Japan Tobacco Inc. to acquire its pharmaceutical business. This strategic move, effective December 25, 2025, aims to enhance Shionogi’s market position by integrating Japan Tobacco’s pharmaceutical operations, potentially impacting stakeholders by expanding Shionogi’s product offerings and market reach.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 11, 2025