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Shionogi & Co (JP:4507)
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Shionogi & Co (4507) AI Stock Analysis

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JP:4507

Shionogi & Co

(OTC:4507)

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Outperform 83 (OpenAI - 4o)
Rating:83Outperform
Price Target:
¥2,919.00
▲(11.56% Upside)
Shionogi & Co's strong financial performance, coupled with positive earnings call results, significantly contributes to the high stock score. Technical indicators suggest bullish momentum, although caution is advised due to high stochastic levels. The stock's attractive valuation, with a low P/E ratio and a solid dividend yield, further enhances its investment appeal. Challenges in certain markets and the need for operational efficiency improvements are areas to watch.
Positive Factors
Negative Factors

Shionogi & Co (4507) vs. iShares MSCI Japan ETF (EWJ)

Shionogi & Co Business Overview & Revenue Model

Company DescriptionShionogi & Co., Ltd. is a leading pharmaceutical company based in Japan, primarily engaged in the research, development, manufacture, and sale of pharmaceutical products. The company operates in various sectors, including prescription drugs, over-the-counter medications, and diagnostic agents. Shionogi is known for its expertise in infectious diseases, pain management, and cardiovascular treatments, with a strong emphasis on innovation and addressing unmet medical needs.
How the Company Makes MoneyShionogi & Co. generates revenue primarily through the sale of its pharmaceutical products, which include both prescription and over-the-counter medications. The company's key revenue streams are derived from its proprietary drugs, particularly in areas such as infectious diseases and pain management. Shionogi also engages in strategic partnerships and collaborations with other pharmaceutical companies and research institutions, which can provide additional revenue through licensing agreements and joint development projects. The company invests heavily in research and development to sustain its pipeline of new drugs, ensuring a continuous flow of innovative products to the market. Additionally, Shionogi may earn income from royalties, milestone payments, and other financial arrangements related to its patented drugs and technology.

Shionogi & Co Earnings Call Summary

Earnings Call Date:Jul 28, 2025
(Q1-2025)
|
% Change Since: |
Next Earnings Date:Oct 27, 2025
Earnings Call Sentiment Positive
The earnings call highlighted strong financial performance and growth in the HIV business, along with successful M&A activities and advancements in drug development. These positives were tempered by declines in domestic and overseas sales, particularly in China, and concerns regarding R&D cost management. Despite these challenges, the overall outlook remains optimistic due to strategic growth initiatives.
Q1-2025 Updates
Positive Updates
Strong Financial Performance
Revenue for Q1 FY2025 increased to JPY99.8 billion, a rise of JPY2.2 billion compared to the same period last year. Operating profit increased by JPY7 billion to JPY35.1 billion, and profit before tax rose by JPY9.8 billion to JPY46.3 billion. Profit attributable to owners of the parent was JPY39.4 billion, an increase of JPY8.7 billion.
HIV Business Growth
The HIV business showed strong growth, with ViiV's HIV franchise contributing to higher royalty income. Long-acting formulations like Cabenuva and Dovato are driving this growth.
Advancements in Drug Development
Significant progress in the development pipelines, including the filing of Ensitrelvir in Europe and the US. The development of S-365598, a third-generation integrase inhibitor, is ongoing with promising antiviral activity.
Successful M&A Activity
Completion of the tender offer for Torii Pharmaceutical and progress towards merging with the JT Group pharmaceutical business.
Negative Updates
Decline in Domestic and Overseas Business
Domestic prescription drug sales decreased by JPY1.3 billion to JPY14.1 billion, mainly due to reduced sales of drugs for acute respiratory virus infections. Overseas subsidiaries/exports segment also declined by JPY0.7 billion.
Challenges in China
Sales in the China business declined, impacting the overall performance of the overseas segment.
R&D Cost Management Concerns
R&D expenses decreased by JPY4.5 billion due to the completion of multiple large-scale clinical trials, raising concerns about the current level of investment in growth drivers.
Company Guidance
During the first quarter financial results briefing for fiscal year 2025, SHIONOGI reported significant growth in both financial and non-financial metrics. The company achieved a year-over-year increase in revenue to JPY99.8 billion, up by JPY2.2 billion, with operating profit reaching JPY35.1 billion, an increase of JPY7 billion. Profit before tax rose to JPY46.3 billion, up by JPY9.8 billion, and profit attributable to owners of the parent increased by JPY8.7 billion to JPY39.4 billion. EBITDA also saw a rise to JPY40.6 billion, marking a JPY7 billion increase. Significant contributors to this growth included the strong performance of the HIV business, with revenue from this segment driven by ViiV's HIV franchise and royalty income from Roche's Xofluza, which benefited from a flu epidemic in China and the U.S. Non-financial milestones included the completion of a tender offer for Torii Pharmaceutical and progress towards an M&A with the JT Group's pharmaceutical business. The company's strategic focus on pipeline developments, including the filing of Ensitrelvir in Europe and the U.S., is expected to support medium- to long-term growth.

Shionogi & Co Financial Statement Overview

Summary
Shionogi & Co exhibits strong financial performance with consistent revenue growth and high profitability margins. The balance sheet is robust with low leverage, and cash flow management is effective, indicating solid liquidity and financial flexibility. There is room for operational efficiency and asset utilization improvements.
Income Statement
85
Very Positive
Shionogi & Co has demonstrated strong financial performance with a consistent increase in revenue, achieving a revenue growth rate from the previous year. The company maintains robust profitability with a high gross profit margin and a notable net profit margin. EBIT and EBITDA margins are also strong, indicating efficient cost management. However, slight fluctuations in EBIT indicate potential areas for operational improvements.
Balance Sheet
82
Very Positive
The balance sheet reveals a solid financial position with a low debt-to-equity ratio, reflecting prudent financial management and low leverage risk. The return on equity is impressive, showcasing effective utilization of shareholder funds. The equity ratio is high, indicating substantial equity financing, which enhances financial stability. Despite these strengths, the high stockholders' equity relative to total assets suggests room for optimizing asset utilization.
Cash Flow
88
Very Positive
Shionogi & Co's cash flow statement highlights strong cash generation capabilities, with significant free cash flow growth. The operating cash flow to net income ratio is robust, reflecting effective conversion of accounting profits to cash. The free cash flow to net income ratio further underscores the company's capability to generate cash exceeding net income. These metrics indicate solid liquidity and financial flexibility.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue438.27B438.27B435.08B426.68B335.14B297.18B
Gross Profit372.45B370.26B369.09B364.44B279.72B244.65B
EBITDA210.02B230.71B186.70B176.41B143.42B158.67B
Net Income170.43B170.43B162.03B184.97B114.19B111.86B
Balance Sheet
Total Assets1.54T1.54T1.42T1.31T1.15T998.99B
Cash, Cash Equivalents and Short-Term Investments374.80B374.80B358.09B563.36B465.18B418.32B
Total Debt21.88B21.88B11.62B9.41B6.67B7.99B
Total Liabilities172.85B172.85B164.36B189.92B157.32B134.44B
Stockholders Equity1.36T1.36T1.24T1.10T975.66B846.11B
Cash Flow
Free Cash Flow178.33B178.33B126.02B140.68B70.50B76.09B
Operating Cash Flow195.46B195.46B154.28B177.87B102.07B109.04B
Investing Cash Flow-129.07B-129.07B5.92B-48.29B-96.20B-5.26B
Financing Cash Flow-51.92B-51.92B-126.85B-84.12B-36.62B-43.89B

Shionogi & Co Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2616.50
Price Trends
50DMA
2572.03
Positive
100DMA
2495.76
Positive
200DMA
2354.90
Positive
Market Momentum
MACD
18.46
Positive
RSI
50.69
Neutral
STOCH
33.95
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4507, the sentiment is Positive. The current price of 2616.5 is above the 20-day moving average (MA) of 2608.00, above the 50-day MA of 2572.03, and above the 200-day MA of 2354.90, indicating a bullish trend. The MACD of 18.46 indicates Positive momentum. The RSI at 50.69 is Neutral, neither overbought nor oversold. The STOCH value of 33.95 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4507.

Shionogi & Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
83
Outperform
¥2.30T12.4213.71%2.19%4.04%21.20%
76
Outperform
305.42B15.847.86%2.48%6.49%38.42%
75
Outperform
284.00B11.1310.79%3.66%14.60%8.97%
67
Neutral
1.44T29.085.52%3.13%9.43%56.53%
65
Neutral
7.02T51.191.99%4.42%1.52%-8.68%
63
Neutral
642.82B34.0110.73%26.28%0.00%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4507
Shionogi & Co
2,649.50
572.50
27.56%
DNPUF
Sumitomo Dainippon Pharma Co
11.58
7.28
169.30%
ESALF
Eisai Co
34.23
-2.74
-7.41%
HTSUF
Hisamitsu Pharmaceutical Co
28.55
1.35
4.96%
TKPHF
Takeda Pharmaceutical Co
28.20
-0.84
-2.89%
TSMRF
Tsumura & Co
23.20
-4.23
-15.42%

Shionogi & Co Corporate Events

Shionogi & Co. Reports Strong Q1 2025 Financial Results
Jul 28, 2025

Shionogi & Co. reported its consolidated financial results for the first quarter of fiscal year 2025, showing a revenue increase of 2.2% compared to the previous year. The company also experienced significant growth in operating profit and profit before tax, indicating strong financial performance. The company’s financial forecast for the year ending March 2026 anticipates continued revenue and profit growth, reflecting positive market positioning and operational efficiency.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen2750.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Highlights ViiV Healthcare’s Study on Long-Acting Injectable HIV Treatment
Jul 24, 2025

Shionogi & Co., Ltd. announced that ViiV Healthcare presented results from the VOLITION study at the IAS 2025, showing that 89% of HIV patients preferred switching from daily oral therapy to the long-acting injectable Cabenuva. This preference highlights the potential for improved adherence and treatment satisfaction, reinforcing Shionogi’s commitment to infectious disease solutions and its strategic positioning in the global health market.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen2750.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Completes Disposal of Treasury Shares for Compensation Plan
Jul 17, 2025

Shionogi & Co., Ltd. has completed the disposal of 200,400 treasury shares as part of a restricted stock compensation plan, with a total value of approximately ¥500 million. This move is aimed at aligning the interests of directors and officers with the company’s performance, potentially impacting the company’s governance and stakeholder relations.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen2750.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Expands COVID-19 Drug Use to Younger Patients
Jun 30, 2025

Shionogi & Co., Ltd. has submitted a supplemental New Drug Application in Japan to expand the use of its oral antiviral drug, ensitrelvir, for treating COVID-19 in pediatric patients aged 6 years and older. This move follows positive Phase 3 study results showing the drug’s safety and efficacy in children, and if approved, it will address the unmet need for oral antiviral treatments in this age group. Ensitrelvir, also known as Xocova® in some markets, has already received emergency and full regulatory approval in Japan and is under review in other regions. The drug has shown promising results in preventing symptomatic COVID-19 in post-exposure scenarios, marking a significant step in Shionogi’s efforts to strengthen its position in the antiviral market.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen7400.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Completes Tender Offer for Torii Pharmaceutical Shares
Jun 19, 2025

Shionogi & Co., Ltd. announced the successful completion of its tender offer for shares of Torii Pharmaceutical Co., Ltd., which will become an equity-method affiliate of Shionogi as of June 25, 2025. This acquisition is expected to enhance Shionogi’s market position and expand its influence in the pharmaceutical industry, potentially impacting stakeholders by increasing the company’s operational scope and strategic capabilities.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen2750.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Announces Treasury Shares Disposal for Compensation Plan
Jun 18, 2025

Shionogi & Co., Ltd. announced the disposal of 200,400 treasury shares as part of a restricted stock compensation plan aimed at incentivizing directors and corporate officers to enhance corporate value. This move, approved by the Board of Directors, aligns with the company’s strategy to promote shared values with shareholders and adapt its governance structure, potentially impacting its market positioning and stakeholder relations.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen2750.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Amends Tender Offer for Torii Amid Patent Lawsuit
Jun 4, 2025

Shionogi & Co., Ltd. announced an amendment to its tender offer for shares of Torii Pharmaceutical Co., Ltd. due to a patent infringement lawsuit involving Torii’s oral antipruritus medication, REMITCH®. Despite the legal proceedings, Torii’s stance on the tender offer remains unchanged, as the financial implications of the lawsuit are still uncertain.

The most recent analyst rating on (JP:4507) stock is a Hold with a Yen2750.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi’s Naldemedine Gains Approval in China for Opioid-Induced Constipation
May 30, 2025

Shionogi & Co., Ltd. announced the acceptance of its New Drug Application for naldemedine, a treatment for opioid-induced constipation, in China. This approval is expected to enhance pain management options in China, where current treatments are limited, and improve the quality of life for patients. The drug, already available in several regions, demonstrated significant efficacy in a Phase III trial in China. Following approval, Shionogi China Co., Ltd. will handle sales through an exclusive agreement with Chia Tai Tianqing Pharmaceutical Group Co., Ltd., potentially boosting Shionogi’s market presence and revenue in China.

The most recent analyst rating on (JP:4507) stock is a Buy with a Yen3100.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Amends Tender Offer for Torii Pharmaceutical Shares
May 28, 2025

Shionogi & Co., Ltd. has announced amendments to its tender offer for shares of Torii Pharmaceutical Co., Ltd., following a notice from the Japan Fair Trade Commission. These amendments, which do not alter the terms of purchase, are necessary to update the Tender Offer Statement and ensure compliance with regulatory requirements, reflecting the company’s commitment to adhere to legal standards in its acquisition efforts.

The most recent analyst rating on (JP:4507) stock is a Buy with a Yen3100.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi Proposes Governance Structure Overhaul to Enhance Strategic Oversight
May 16, 2025

Shionogi & Co., Ltd. announced its decision to propose amendments to its Articles of Incorporation at the upcoming Annual General Meeting of Shareholders. The amendments aim to transition the company to a structure with an Audit and Supervisory Committee, enhancing corporate governance and facilitating strategic decision-making. This move is expected to strengthen oversight, promote globalization, and support business model transformation, potentially impacting the company’s operational efficiency and stakeholder engagement.

The most recent analyst rating on (JP:4507) stock is a Buy with a Yen3100.00 price target. To see the full list of analyst forecasts on Shionogi & Co stock, see the JP:4507 Stock Forecast page.

Shionogi & Co. Reports Fiscal Year 2024 Financial Results with Positive Outlook
May 12, 2025

Shionogi & Co., Ltd. reported its consolidated financial results for the fiscal year 2024, showing a slight increase in revenue and operating profit compared to the previous year. The company conducted a 3-for-1 stock split effective October 2024, which impacted earnings per share calculations. Despite a decline in comprehensive income, the company forecasts significant growth in revenue and profit for the fiscal year ending March 2026, indicating a positive outlook for stakeholders.

Shionogi Announces Tender Offer to Acquire TORII Pharmaceutical
May 7, 2025

Shionogi & Co., Ltd. has announced the commencement of a tender offer to acquire all shares of TORII PHARMACEUTICAL CO., LTD., aiming to make it a wholly-owned subsidiary. This strategic move is part of a broader transaction involving stock consolidation and capital restructuring, which is expected to enhance Shionogi’s market position and operational capabilities by integrating TORII’s resources and expertise.

Shionogi Expands Pharmaceutical Capabilities with Strategic Acquisitions
May 7, 2025

Shionogi & Co., Ltd. announced a strategic move to acquire the pharmaceutical business of Japan Tobacco Inc. and make Akros Pharma Inc. a sub-subsidiary, enhancing its capabilities in small molecule drug discovery. This transaction aligns with Shionogi’s vision of creating a new healthcare platform and aims to accelerate the development of innovative drugs, strengthen its global market position, and contribute to global health by delivering advanced pharmaceuticals.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 30, 2025