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Sumitomo Dainippon Pharma Co Ltd (JP:4506)
:4506

Sumitomo Dainippon Pharma Co (4506) AI Stock Analysis

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JP:4506

Sumitomo Dainippon Pharma Co

(4506)

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Neutral 62 (OpenAI - 5.2)
Rating:62Neutral
Price Target:
¥2,675.00
▲(10.47% Upside)
Action:ReiteratedDate:02/18/26
The score is driven primarily by improving financial performance with strong current profitability and positive free cash flow, but held back by significant recent volatility and uneven cash conversion. Technicals are supportive with strong trend strength, though overbought signals add near-term risk. Valuation is a modest positive due to the low P/E.
Positive Factors
Robust TTM margins
Sustained high TTM net and EBIT margins indicate durable pricing power and operational efficiency in core therapeutic areas. Strong margins provide internal funding for R&D and commercialization, supporting long-term competitiveness even if top-line growth is modest.
Positive free cash flow
Material positive free cash flow, close to reported earnings, enhances the company's ability to self-fund development, pay down debt, and invest in launches. Improved FCF versus prior periods strengthens financial flexibility for durable strategic execution.
Established pharmaceutical business model
Integrated drug R&D, manufacturing and global marketing creates diversified revenue channels (in-house, licensed, and collaboration income). This vertically integrated model and international presence support steady demand and multiple paths to replenish the pipeline over the medium term.
Negative Factors
Earnings and revenue volatility
History of large losses and sharp revenue swings signals unstable product lifecycles or one-off impacts. Such volatility impairs forecasting, capital allocation and investor confidence, raising the risk that margins and cash generation may not persist consistently over the next several quarters.
Weak operating cash conversion
Low operating cash conversion versus reported earnings suggests working-capital timing or noncash earnings components. This inconsistency can constrain funding for R&D and launches, forcing reliance on financing in weak periods and making sustainable investment programs harder to maintain.
Balance-sheet volatility and prior elevated leverage
Although leverage improved TTM, prior periods of substantially higher debt and swings in equity indicate balance-sheet sensitivity. This history increases vulnerability to shocks and could limit strategic flexibility if cashflows weaken or if new large investments are required.

Sumitomo Dainippon Pharma Co (4506) vs. iShares MSCI Japan ETF (EWJ)

Sumitomo Dainippon Pharma Co Business Overview & Revenue Model

Company DescriptionSumitomo Pharma Co., Ltd. manufactures and sells pharmaceuticals, food ingredients and additives, veterinary medicines, and others in Japan, North America, China, and internationally. The company offers pharmaceutical products, such as therapeutic agents for Parkinson's disease, depression, type 2 diabetes, systemic fungal infection, hypertension, pruritus, chronic obstructive pulmonary disease, angina pectoris, and arrhythmia. It also provides products for atypical antipsychotic, antiepileptic, carbapenem antibiotic, and gastrointestinal; and Anderson-Fabry disease drugs. In addition, the company offers food ingredients and additives, such as polysaccharides, as well as seasonings, such as soups or bouillons; and chemical product materials, which include pharmaceutical excipients, personal care products, coatings and industrial materials, and electronic materials. Further, it provides veterinary medicines for companion animals, such as dogs and cats; and livestock comprising cattle, swine, poultry, horses, and aquacultured fish. Sumitomo Pharma Co., Ltd. has partnerships with Healios K.K.; Keio University; RIKEN; the Center for iPS Cell Research and Application; Kyoto University; and Aikomi Co., Ltd., as well as a joint development agreement with SanBio Company Limited; and collaboration and license agreement with Otsuka Pharmaceutical Co., Ltd. It also has a strategic alliance with Roivant Sciences Ltd. The company was formerly known as Sumitomo Dainippon Pharma Co., Ltd. and changed its name to Sumitomo Pharma Co., Ltd. in April 2022. The company was founded in 1897 and is headquartered in Osaka, Japan. Sumitomo Pharma Co., Ltd. is a subsidiary of Sumitomo Chemical Company, Limited.
How the Company Makes MoneySumitomo Dainippon Pharma generates revenue primarily through the sale of its pharmaceutical products, which include a diverse portfolio of prescription drugs and specialty medications. The company has established key revenue streams from its proprietary drugs, particularly in psychiatry and neurology, as well as from partnerships and collaborations that enhance its drug pipeline. Additionally, the company engages in licensing agreements and joint ventures with other pharmaceutical companies to expand its market reach and share the costs of research and development. Collaborations with biotech firms and research institutions also provide access to innovative therapies, further contributing to Sumitomo Dainippon Pharma's earnings. The company is also involved in the global market, which helps diversify its revenue sources.

Sumitomo Dainippon Pharma Co Earnings Call Summary

Earnings Call Date:Jan 31, 2025
(Q3-2024)
|
% Change Since: |
Next Earnings Date:May 19, 2026
Earnings Call Sentiment Negative
The earnings call highlighted promising developments in the oncology and regenerative medicine pipelines but was overshadowed by significant financial losses, decreased revenue across all segments, and underperformance of key products, leading to a revised downward financial forecast. The call focused on strategic adjustments to address market challenges and improve profitability.
Q3-2024 Updates
Positive Updates
Development Progress in iPS Cell-Derived Therapies
Significant progress in clinical development in regenerative medicine, particularly in Parkinson's disease using iPS cell-derived dopaminergic progenitor cells. The University of California San Diego began a study in November 2023, with ongoing trials in Japan.
Oncology Pipeline Advancements
Promising interim results for TP-3654 in myelofibrosis and DSP-5336 in acute leukemia, with observed reductions in spleen volume and bone marrow blasts respectively, and good tolerability in trials.
Negative Updates
Significant Revenue Decline
Revenue was JPY 235 billion, a decrease of JPY 225.2 billion compared to the same period last year, with declines across all segments, including Japan, North America, and Asia.
Core Operating and Net Profit Losses
Core operating profit decreased by JPY 139.3 billion year-on-year, resulting in a loss of JPY 96.4 billion. Net profit attributable to owners also decreased, resulting in a loss of JPY 117.7 billion.
Challenges in North America
The North America segment saw a revenue decrease of JPY 164 billion compared to the same period last year, heavily impacted by the end of the exclusive sales period of LATUDA.
Underperformance of Key Products
Significant downward revisions for ORGOVYX, MYFEMBREE, and GEMTESA forecasts due to slower than expected market penetration and increased competition.
Financial Forecast Revisions
Revenue forecast revised down by JPY 45 billion, with core operating profit expected to see a reduction of JPY 72 billion, forecasting a loss of JPY 134 billion.
Potential Impairment Concerns
Possibility of impairment for key products due to underperformance and downward revisions of their outlook.
Company Guidance
During the Q3 2024 earnings call for Sumitomo Pharma, several key financial metrics and strategic adjustments were discussed. Revenue for Q3 2023 was reported at JPY 235 billion, which marked a significant decrease of JPY 225.2 billion from the same period in the previous year. The decline was attributed to reduced revenue across all segments, including Japan, North America, and Asia. Despite a decrease in SG&A expenses and some operating income from the sale of shares in Sumitomo Pharma Animal Health, the core operating profit decreased by JPY 139.3 billion, resulting in a core operating loss of JPY 96.4 billion. The company also recorded a JPY 20.5 billion nonrecurring expense related to restructuring in North America, contributing to an operating loss of JPY 117.7 billion. Additionally, profit before taxes saw a year-on-year decrease of JPY 107.4 billion, resulting in a quarterly loss of JPY 105.2 billion. Consequently, the net profit attributable to owners of the parent decreased significantly, resulting in a loss of JPY 117.7 billion. The full-year financial forecast was revised downward, with expectations for revenue at JPY 317 billion, a reduction of JPY 45 billion from previous forecasts. The forecasted core operating profit was expected to see a reduction of JPY 72 billion, projecting a loss of JPY 134 billion. The company is also anticipating a decrease in profit attributable to owners by JPY 61 billion, forecasting a loss of JPY 141 billion. The underperformance was largely due to the North American segment, where key products like ORGOVYX, MYFEMBREE, and GEMTESA fell short of their sales plans.

Sumitomo Dainippon Pharma Co Financial Statement Overview

Summary
Strong TTM profitability recovery (net margin ~24%, EBIT margin ~25%) with positive free cash flow and improved leverage (debt-to-equity under 1.0). Offsetting this, recent years show pronounced volatility (major FY2024 loss, sharp revenue swings) and weak/uneven cash conversion (operating cash flow ~0.25x of net income), which keeps the score moderate.
Income Statement
62
Positive
Profitability has rebounded sharply in TTM (Trailing-Twelve-Months): net margin is strong (~24%) with solid operating profitability (EBIT margin ~25%) on modest revenue growth (~2%). However, results have been highly volatile—FY2024 showed very large losses and a steep revenue decline, followed by a much weaker but positive FY2025, before the outsized TTM recovery. The key strength is current margin strength; the key weakness is the recent track record of instability in revenue and earnings.
Balance Sheet
55
Neutral
Leverage looks improved in TTM (Trailing-Twelve-Months) with debt-to-equity under 1.0, a meaningful step down from the elevated leverage seen in FY2024–FY2025 (debt-to-equity well above 1.0). Equity levels have also swung significantly across periods, underscoring balance-sheet volatility. Current returns on equity are very strong in TTM, but given the recent large loss year and prior high leverage, the balance sheet still carries risk and warrants a more cautious score.
Cash Flow
57
Neutral
TTM (Trailing-Twelve-Months) free cash flow is positive and up substantially versus the prior period, and free cash flow is relatively close to net income (about 0.88x), which is supportive of earnings quality. That said, operating cash flow remains low relative to reported earnings (about 0.25x in TTM), suggesting working-capital or timing effects. History is also mixed, including a very large cash outflow in FY2024 and weak cash generation in FY2025, so consistency remains the main concern.
BreakdownTTMMar 2026Mar 2025Mar 2024Mar 2023Mar 2022
Income Statement
Total Revenue453.39B398.83B314.56B555.54B560.03B515.95B
Gross Profit268.59B245.40B187.98B376.63B402.91B378.18B
EBITDA137.13B56.67B-281.07B-3.50B124.36B103.11B
Net Income110.09B23.63B-314.97B-74.51B56.41B56.22B
Balance Sheet
Total Assets815.52B742.60B907.51B1.13T1.31T1.31T
Cash, Cash Equivalents and Short-Term Investments57.32B39.96B36.13B143.48B202.98B193.70B
Total Debt258.95B305.42B418.88B346.37B284.54B290.68B
Total Liabilities526.58B573.13B751.37B727.96B634.44B659.95B
Stockholders Equity288.94B169.48B156.06B406.75B607.89B580.57B
Cash Flow
Free Cash Flow47.09B3.47B-257.62B-805.00M17.75B124.80B
Operating Cash Flow53.28B16.50B-241.89B11.94B31.24B135.60B
Investing Cash Flow26.68B99.75B33.04B52.42B-18.28B8.88B
Financing Cash Flow-112.20B-108.84B77.85B-146.82B-21.43B-57.22B

Sumitomo Dainippon Pharma Co Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2421.50
Price Trends
50DMA
2466.81
Negative
100DMA
2313.99
Positive
200DMA
1768.33
Positive
Market Momentum
MACD
11.00
Positive
RSI
48.01
Neutral
STOCH
23.55
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4506, the sentiment is Neutral. The current price of 2421.5 is below the 20-day moving average (MA) of 2490.10, below the 50-day MA of 2466.81, and above the 200-day MA of 1768.33, indicating a neutral trend. The MACD of 11.00 indicates Positive momentum. The RSI at 48.01 is Neutral, neither overbought nor oversold. The STOCH value of 23.55 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for JP:4506.

Sumitomo Dainippon Pharma Co Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
84
Outperform
¥3.12T16.0012.22%2.22%4.48%11.08%
77
Outperform
¥345.32B11.612.12%4.07%22.59%
68
Neutral
¥1.44T34.575.75%3.51%6.79%22.14%
66
Neutral
¥198.51B14.856.57%2.48%13.11%41.57%
65
Neutral
¥9.18T80.610.54%4.11%-2.84%-88.29%
62
Neutral
$962.05B8.7479.99%29.92%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4506
Sumitomo Dainippon Pharma Co
2,421.50
1,708.50
239.62%
JP:4523
Eisai Co
5,098.00
952.59
22.98%
JP:4547
Kissei Pharmaceutical Co
4,860.00
1,270.69
35.40%
JP:4507
Shionogi & Co
3,553.00
1,328.34
59.71%
JP:4502
Takeda Pharmaceutical Co
5,794.00
1,584.50
37.64%
JP:4516
Nippon Shinyaku Co., Ltd.
5,127.00
1,184.83
30.06%

Sumitomo Dainippon Pharma Co Corporate Events

Sumitomo Pharma’s iPS Cell Parkinson’s Therapy Heads to Key Japan Regulatory Review
Feb 13, 2026

Sumitomo Pharma Co., Ltd. and Tokyo-based RACTHERA Inc. have applied for manufacturing and marketing authorization in Japan for AMCHEPRY, an allogeneic iPS cell-derived dopaminergic neural progenitor cell therapy for improving motor function during off-time in patients with advanced Parkinson’s disease. Japan’s Ministry of Health, Labour and Welfare has placed AMCHEPRY on the agenda of its Pharmaceutical Affairs and Food Sanitation Council’s Committee on Regenerative Medicine Products and Biotechnologies meeting on February 19, 2026, where a decision on approval is expected, though the company does not anticipate any impact on earnings for the fiscal year ending March 2026.

The scheduled regulatory review underscores Sumitomo Pharma’s push into cutting-edge regenerative medicine for neurodegenerative disorders, highlighting its bid to secure an early leadership position in cell-based therapies for Parkinson’s disease. While near-term financial effects are expected to be limited, a positive decision could strengthen the company’s longer-term growth prospects and competitive standing in Japan’s high-value, innovation-driven pharmaceuticals market.

The most recent analyst rating on (JP:4506) stock is a Hold with a Yen2481.00 price target. To see the full list of analyst forecasts on Sumitomo Dainippon Pharma Co stock, see the JP:4506 Stock Forecast page.

Sumitomo Pharma Posts Surging Profit and Higher Revenue in Q3 FY2025 Under IFRS
Jan 30, 2026

Sumitomo Pharma reported strong earnings momentum for the third quarter of the fiscal year ending March 31, 2026, with revenue rising to ¥347.7 billion from ¥293.2 billion year-on-year and core operating profit surging more than fourfold to ¥109.4 billion, driven by higher sales, lower selling, general and administrative expenses, and reduced R&D spending. Operating profit jumped to ¥109.8 billion and net profit attributable to owners of the parent climbed to ¥107.7 billion, pushing ROE to 43.0% and ROIC to 20.7%, although cash and cash equivalents declined to ¥57.3 billion amid lower operating cash flow in the prior year and reduced investing inflows, highlighting a trade-off between improved profitability and a tighter liquidity position as the company advances its pipeline and adjusts its cost structure.

The most recent analyst rating on (JP:4506) stock is a Buy with a Yen2501.00 price target. To see the full list of analyst forecasts on Sumitomo Dainippon Pharma Co stock, see the JP:4506 Stock Forecast page.

Sumitomo Pharma Outlines Q3 FY2025 Results With Caution on Forward-Looking Data
Jan 30, 2026

Sumitomo Pharma Co., Ltd. announced that President and CEO Toru Kimura held a conference on January 30, 2026, to discuss the company’s financial results for the third quarter of fiscal year 2025, covering the period from April 1 to December 31, 2025. The company emphasized that the materials presented include forward-looking information based on current assumptions and estimates, and highlighted that actual performance and development outcomes may differ materially due to various risks and uncertainties, underscoring a cautious stance toward projections and the non-promotional, non-medical-advice nature of product-related information provided.

The most recent analyst rating on (JP:4506) stock is a Buy with a Yen2501.00 price target. To see the full list of analyst forecasts on Sumitomo Dainippon Pharma Co stock, see the JP:4506 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 18, 2026