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Nippon Shinyaku Co., Ltd. (JP:4516)
:4516
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Nippon Shinyaku Co., Ltd. (4516) AI Stock Analysis

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JP:4516

Nippon Shinyaku Co., Ltd.

(4516)

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Outperform 76 (OpenAI - 5.2)
Rating:76Outperform
Price Target:
¥4,045.00
▼(-28.41% Downside)
Action:Reiterated
Date:07/29/26
The score is driven primarily by strong financial fundamentals (high margins and a fortress-like, very low-debt balance sheet) and very favorable valuation (low P/E and a healthy dividend yield). These positives are moderated by weak technical positioning, with the stock trading below major moving averages, and by the recent (2026) step-down in profitability and free cash flow that warrants monitoring.
Positive Factors
High margins
Sustained high gross (~66%) and operating (~19%) margins reflect pricing power in specialty pharmaceuticals and a favorable product mix. These margins provide durable capacity to fund R&D, support lifecycle management, and absorb reimbursement pressure, underpinning long-term profitability.
Negative Factors
2026 profit & FCF step-down
A material step-down in margins and FCF in 2026 indicates emerging structural pressures—costs, mix shifts, or higher investments—that could persist. If sustained, this reduces reinvestment capacity, limits excess cash for dividends or deals, and weakens the cushion from the previously strong financial profile.
Read all positive and negative factors
Positive Factors
Negative Factors
High margins
Sustained high gross (~66%) and operating (~19%) margins reflect pricing power in specialty pharmaceuticals and a favorable product mix. These margins provide durable capacity to fund R&D, support lifecycle management, and absorb reimbursement pressure, underpinning long-term profitability.
Read all positive factors

Nippon Shinyaku Co., Ltd. (4516) vs. iShares MSCI Japan ETF (EWJ)

Nippon Shinyaku Co., Ltd. Business Overview & Revenue Model

Company Description
Nippon Shinyaku Co., Ltd., an enterprise established in Kyoto, Japan, in 1911, engages globally in the production and distribution of pharmaceutical products and functional foods. Its reach extends across Japan, Switzerland, and various internatio...
How the Company Makes Money
Nippon Shinyaku primarily makes money by selling products from its Pharmaceuticals segment, which generates revenue from the commercial sale of prescription drugs in Japan and in overseas markets where it has commercialization arrangements. Earnin...

Nippon Shinyaku Co., Ltd. Financial Statement Overview

Summary
Strong overall financial quality supported by high gross margins (~66%), healthy operating margin (~19%), and an extremely low leverage balance sheet (debt-to-equity ~0.9%). Offsetting this, 2026 showed pressure versus 2025 with lower net margin (~17% vs. ~20%), declining operating profit, and a noticeable free cash flow decline (-13.9%), indicating recent profitability and cash generation softness.
Income Statement
86
Very Positive
Balance Sheet
94
Very Positive
Cash Flow
74
Positive
BreakdownMar 2026Mar 2026Mar 2025Mar 2024Mar 2023
Income Statement
Total Revenue170.77B160.23B148.25B144.18B137.55B
Gross Profit113.31B108.10B97.02B87.25B85.98B
EBITDA43.26B42.25B38.70B35.60B37.97B
Net Income29.72B32.56B25.85B22.81B24.99B
Balance Sheet
Total Assets346.36B283.64B263.40B243.27B219.94B
Cash, Cash Equivalents and Short-Term Investments76.59B58.47B68.70B71.59B60.57B
Total Debt2.57B2.72B2.87B2.66B2.71B
Total Liabilities54.48B36.30B42.87B47.33B39.05B
Stockholders Equity291.55B247.03B220.22B195.63B180.59B
Cash Flow
Free Cash Flow24.24B32.77B11.23B20.51B18.18B
Operating Cash Flow27.22B36.13B16.29B26.17B21.32B
Investing Cash Flow1.98B-28.88B-9.92B-17.63B-10.04B
Financing Cash Flow-9.93B-9.90B-9.72B-9.61B-8.41B

Nippon Shinyaku Co., Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5650.00
Price Trends
50DMA
3982.02
Negative
100DMA
4442.92
Negative
200DMA
4506.07
Negative
Market Momentum
MACD
-163.61
Positive
RSI
26.54
Positive
STOCH
7.74
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4516, the sentiment is Negative. The current price of 5650 is above the 20-day moving average (MA) of 3881.70, above the 50-day MA of 3982.02, and above the 200-day MA of 4506.07, indicating a bearish trend. The MACD of -163.61 indicates Positive momentum. The RSI at 26.54 is Positive, neither overbought nor oversold. The STOCH value of 7.74 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4516.

Nippon Shinyaku Co., Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
¥229.00B7.712.12%6.58%-8.75%
73
Outperform
¥2.56T12.0613.65%2.45%14.01%20.33%
71
Outperform
¥1.36T35.314.44%3.44%4.56%-16.55%
68
Neutral
¥559.84B4.4641.78%14.09%488.06%
64
Neutral
¥8.80T129.502.61%3.54%3.10%-218.63%
64
Neutral
¥262.10B14.871.81%2.30%-13.73%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4516
Nippon Shinyaku Co., Ltd.
3,473.00
257.60
8.01%
JP:4506
Sumitomo Dainippon Pharma Co
1,273.50
7.50
0.59%
JP:4523
Eisai Co
4,520.00
405.08
9.84%
JP:4507
Shionogi & Co
2,758.00
191.89
7.48%
JP:4502
Takeda Pharmaceutical Co
5,269.00
1,196.47
29.38%
JP:8129
Toho Holdings Co., Ltd.
3,613.00
-1,550.26
-30.02%

Nippon Shinyaku Co., Ltd. Corporate Events

Nippon Shinyaku Uses Restricted Stock to Tighten Director-Shareholder Alignment
Jul 21, 2026
Nippon Shinyaku Co., Ltd., a Japan-based pharmaceutical maker listed on the Tokyo Stock Exchange Prime Market, develops prescription drugs and healthcare products for domestic and international markets. The company relies on structured executive c...
Nippon Shinyaku Posts Revenue Growth but Lower Profit, Keeps Dividend Steady
May 15, 2026
Nippon Shinyaku reported consolidated revenue of ¥170.8 billion for the year ended March 31, 2026, up 6.6%, while operating profit was flat and profit attributable to owners of the parent fell 8.7%, reflecting pressure on margins despite top-...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 29, 2026