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Nippon Shinyaku Co., Ltd. (JP:4516)
:4516
Japanese Market
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Nippon Shinyaku Co., Ltd. (4516) AI Stock Analysis

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JP:4516

Nippon Shinyaku Co., Ltd.

(4516)

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Neutral 67 (OpenAI - 5.2)
Rating:67Neutral
Price Target:
¥4,597.00
▼(-18.64% Downside)
Action:Downgraded
Date:05/16/26
The score is anchored by strong financial quality (high margins and a fortress balance sheet) and a reasonable valuation (low P/E with a ~2.9% yield). These positives are meaningfully offset by weak technicals, with the stock in a clear downtrend and negative momentum despite oversold readings.
Positive Factors
High margin profile
Sustained high gross and operating margins indicate durable pricing power and a capital-light product mix typical of specialty pharmaceuticals. This margin cushion supports long-term R&D funding, lifecycle investments, and resilience to cost swings, preserving core profitability over time.
Negative Factors
Recent margin and profit pressure
A material step-down in margins and operating profit signals emerging cost, mix, or investment pressures that could persist. If structural (e.g., higher SG&A or escalating launch costs), sustained margin erosion would constrain reinvestment capacity and long-term earnings durability.
Read all positive and negative factors
Positive Factors
Negative Factors
High margin profile
Sustained high gross and operating margins indicate durable pricing power and a capital-light product mix typical of specialty pharmaceuticals. This margin cushion supports long-term R&D funding, lifecycle investments, and resilience to cost swings, preserving core profitability over time.
Read all positive factors

Nippon Shinyaku Co., Ltd. (4516) vs. iShares MSCI Japan ETF (EWJ)

Nippon Shinyaku Co., Ltd. Business Overview & Revenue Model

Company Description
Nippon Shinyaku Co., Ltd. manufactures and sells pharmaceuticals and foodstuffs in Japan, Switzerland, and internationally. The company operates through Pharmaceuticals and Functional Food segments. It offers drugs for urological diseases, inflamm...
How the Company Makes Money
Nippon Shinyaku primarily makes money by selling products from its Pharmaceuticals segment, which generates revenue from the commercial sale of prescription drugs in Japan and in overseas markets where it has commercialization arrangements. Earnin...

Nippon Shinyaku Co., Ltd. Financial Statement Overview

Summary
Strong overall fundamentals supported by high gross margins (~66%), healthy operating margin (~19%), and an exceptionally low-leverage balance sheet (debt-to-equity ~0.9%). Offsetting this, 2026 showed profitability and cash-flow softness versus 2025 (net margin down to ~17%, operating profit down, and free cash flow -13.9%), which tempers the otherwise high-quality profile.
Income Statement
86
Very Positive
Balance Sheet
94
Very Positive
Cash Flow
74
Positive
BreakdownMar 2026Mar 2026Mar 2025Mar 2024Mar 2023
Income Statement
Total Revenue170.77B160.23B148.25B144.18B137.55B
Gross Profit113.31B108.10B97.02B87.25B85.98B
EBITDA39.66B42.78B36.41B34.29B32.89B
Net Income29.72B32.56B25.85B22.81B24.99B
Balance Sheet
Total Assets346.36B283.64B263.40B243.27B219.94B
Cash, Cash Equivalents and Short-Term Investments76.59B58.47B68.70B71.59B60.57B
Total Debt2.57B2.72B2.87B2.66B2.71B
Total Liabilities54.48B36.30B42.87B47.33B39.05B
Stockholders Equity291.55B247.03B220.22B195.63B180.59B
Cash Flow
Free Cash Flow24.24B32.77B11.23B20.51B18.18B
Operating Cash Flow27.22B36.13B16.29B26.17B21.32B
Investing Cash Flow1.98B-28.88B-9.92B-17.63B-10.04B
Financing Cash Flow-9.93B-9.90B-9.72B-9.61B-8.41B

Nippon Shinyaku Co., Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5650.00
Price Trends
50DMA
4903.82
Negative
100DMA
5070.93
Negative
200DMA
4306.07
Negative
Market Momentum
MACD
-220.14
Negative
RSI
31.40
Neutral
STOCH
56.02
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4516, the sentiment is Negative. The current price of 5650 is above the 20-day moving average (MA) of 4461.00, above the 50-day MA of 4903.82, and above the 200-day MA of 4306.07, indicating a bearish trend. The MACD of -220.14 indicates Negative momentum. The RSI at 31.40 is Neutral, neither overbought nor oversold. The STOCH value of 56.02 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4516.

Nippon Shinyaku Co., Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
¥2.60T14.3912.22%2.22%14.01%20.33%
67
Neutral
¥283.49B22.212.12%6.58%-8.74%
65
Neutral
¥1.17T35.615.75%3.51%4.56%-16.55%
64
Neutral
¥278.62B26.971.81%2.30%-13.85%
58
Neutral
¥677.15B7.7248.92%13.66%352.17%
58
Neutral
¥8.10T46.520.54%4.11%-1.66%78.06%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4516
Nippon Shinyaku Co., Ltd.
4,211.00
897.61
27.09%
JP:4506
Sumitomo Dainippon Pharma Co
1,603.00
813.00
102.91%
JP:4523
Eisai Co
4,143.00
395.12
10.54%
JP:4507
Shionogi & Co
3,029.00
724.19
31.42%
JP:4502
Takeda Pharmaceutical Co
5,104.00
1,091.99
27.22%
JP:8129
Toho Holdings Co., Ltd.
4,111.00
-282.70
-6.43%

Nippon Shinyaku Co., Ltd. Corporate Events

Nippon Shinyaku Posts Revenue Growth but Lower Profit, Keeps Dividend Steady
May 15, 2026
Nippon Shinyaku reported consolidated revenue of ¥170.8 billion for the year ended March 31, 2026, up 6.6%, while operating profit was flat and profit attributable to owners of the parent fell 8.7%, reflecting pressure on margins despite top-...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 16, 2026