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Ascletis Pharma, Inc. (HK:1672)
:1672
Hong Kong Market
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Ascletis Pharma, Inc. (1672) AI Stock Analysis

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HK:1672

Ascletis Pharma, Inc.

(1672)

Rating:56Neutral
Price Target:
HK$12.00
▲(5.45%Upside)
Ascletis Pharma's stock score reflects financial challenges, with negative earnings and cash flow issues being significant concerns. Despite strong technical indicators suggesting momentum, valuation remains a concern due to negative P/E. The lack of earnings call and corporate events data leaves room for uncertainty in future performance.

Ascletis Pharma, Inc. (1672) vs. iShares MSCI Hong Kong ETF (EWH)

Ascletis Pharma, Inc. Business Overview & Revenue Model

Company DescriptionAscletis Pharma Inc., a biotechnology company, engages in the research and development, manufacture, marketing, and sale of pharmaceutical products in Mainland China and internationally. The company offers Ritonavir oral tablet, a pharmacokinetic booster of various oral antiviral drugs targeting viral proteases and a component of the approved oral antiviral drug Paxlovid; ASCLEVIR and GANOVO for the treatment of Hepatitis C virus. It is also developing ASC22 for treating chronic hepatitis B (CHB) and human immunodeficiency virus functional cure; ASC42 for chronic hepatitis B functional cure; ASC10 and ASC11 to treat COVID-19; ASC40, ASC41, ASC42, ASC43F FDC, ASC44F FDC, and ASC45F FDC for non-alcoholic steatohepatitis; and ASC42 for the treatment of primary biliary cholangitis. In addition, the company is developing ASC40 to treat recurrent glioblastoma, drug resistant breast cancer, and KRAS mutant non-small cell lung cancer; ASC61 and ASC63 for advanced solid tumors; ASC60 to treat solid tumors; and ASC40 for the treatment of acne, Ascletis Pharma Inc. was founded in 2013 and is headquartered in Hangzhou, the People's Republic of China.
How the Company Makes MoneyAscletis Pharma, Inc. generates revenue primarily through the sale of pharmaceutical products across its key therapeutic areas. The company invests heavily in research and development to bring new drugs to market and collaborates with various partners to enhance its product offerings and expand its market reach. Revenue streams also include licensing agreements, where the company licenses its proprietary technologies and drug candidates to other pharmaceutical companies. Additionally, Ascletis may receive milestone payments and royalties as part of these collaborations and licensing deals, further contributing to its earnings.

Ascletis Pharma, Inc. Financial Statement Overview

Summary
Ascletis Pharma's financial performance is mixed. The income statement reveals ongoing operational struggles with negative net profit and EBIT margins, leading to a low score. However, the balance sheet is strong with a high equity ratio and low debt levels, contributing positively. Cash flow generation remains a concern with negative operating and free cash flow, reflecting potential future liquidity issues.
Income Statement
35
Negative
Ascletis Pharma's income statement reveals significant challenges in terms of profitability. The company has a negative net profit margin and EBIT margin, indicating ongoing operational and financial struggles. Despite an increase in total revenue in 2024, the company continues to incur substantial losses, and the revenue growth has been inconsistent over the years. The biotechnology industry often requires high R&D investments, which could explain the persistent negative earnings, but it poses a risk if this trend continues.
Balance Sheet
70
Positive
The balance sheet of Ascletis Pharma shows a strong equity base, with a high equity ratio indicating stability. The company has maintained a low level of debt relative to equity, which is a positive sign of financial prudence. However, the persistent net losses have not yet impacted the equity base severely. The company's large cash reserves provide a buffer against operational losses, though continued losses could eventually erode this financial cushion.
Cash Flow
40
Negative
The cash flow statements highlight a concerning lack of positive cash flow generation. Ascletis Pharma has struggled to generate operating cash flow, and free cash flow remains negative, indicating the company's difficulty in achieving self-sustaining operations. While cash reserves remain robust, the lack of cash flow from core operations suggests potential liquidity issues if the trend continues without improvements in operational efficiency or revenue generation.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue1.28M56.60M54.09M76.88M35.00M
Gross Profit735.00K25.99M-24.69M39.17M-23.50M
EBITDA-390.58M-126.09M-284.50M-169.35M-181.94M
Net Income-300.94M-144.72M-366.71M-202.14M-262.05M
Balance Sheet
Total Assets2.12B2.49B2.66B2.83B3.07B
Cash, Cash Equivalents and Short-Term Investments1.95B2.30B2.48B2.50B2.71B
Total Debt7.63M8.42M4.24M2.75M1.59M
Total Liabilities158.41M148.94M117.16M100.89M85.42M
Stockholders Equity1.97B2.34B2.54B2.73B2.98B
Cash Flow
Free Cash Flow-343.73M-163.32M-156.85M-154.13M-123.87M
Operating Cash Flow-341.58M-144.16M-142.45M-146.93M-84.91M
Investing Cash Flow978.91M149.84M-1.30B-274.49M132.30M
Financing Cash Flow-103.51M-81.50M-1.42M-31.10M-21.67M

Ascletis Pharma, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price11.38
Price Trends
50DMA
8.55
Positive
100DMA
7.72
Positive
200DMA
5.15
Positive
Market Momentum
MACD
0.62
Negative
RSI
58.46
Neutral
STOCH
78.21
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:1672, the sentiment is Positive. The current price of 11.38 is above the 20-day moving average (MA) of 9.54, above the 50-day MA of 8.55, and above the 200-day MA of 5.15, indicating a bullish trend. The MACD of 0.62 indicates Negative momentum. The RSI at 58.46 is Neutral, neither overbought nor oversold. The STOCH value of 78.21 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HK:1672.

Ascletis Pharma, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
HK$35.49B39.8931.65%4.23%47.71%
59
Neutral
HK$13.72B-51.40%58.75%-1310.16%
56
Neutral
HK$11.03B-13.97%-97.81%-117.20%
53
Neutral
HK$14.02B-55.68%-4.33%
52
Neutral
$7.46B-0.04-63.82%2.49%16.43%<0.01%
45
Neutral
HK$4.02B-69.97%3.30%
HK$9.52B107.314.95%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:1672
Ascletis Pharma, Inc.
10.52
9.38
822.81%
HK:2157
Lepu Biopharma Co. Ltd. Class H
7.38
4.55
160.78%
HK:2171
CARsgen Therapeutics Holdings Ltd.
23.85
19.49
447.02%
HK:2179
Jiangsu Recbio Technology Co., Ltd. Class H
8.40
-0.58
-6.46%
HK:2696
Shanghai Henlius Biotech, Inc. Class H
62.00
39.50
175.56%
HK:6955
Shandong Boan Biotechnology Company., Limited. Class H
16.58
7.51
82.80%

Ascletis Pharma, Inc. Corporate Events

Ascletis Pharma to Review Interim Results and Dividend Proposal
Jul 21, 2025

Ascletis Pharma Inc. has announced a board meeting scheduled for August 15, 2025, to discuss and approve the interim results for the first half of the year and consider the recommendation of an interim dividend. This meeting is significant as it may impact the company’s financial strategy and shareholder returns, reflecting its operational progress and market positioning.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Completes Dosing in U.S. Obesity Treatment Study
Jul 14, 2025

Ascletis Pharma Inc. has completed dosing all participants in its U.S.-based clinical study evaluating the combination of its adipose-targeted, ultra-long-acting small molecule THR β agonist, ASC47, with semaglutide for obesity treatment. The study aims to assess the safety, tolerability, and preliminary efficacy of this combination, with topline data expected in the fourth quarter of 2025. The rapid enrollment of participants highlights the interest in new obesity treatments and the potential benefits of combination therapies, which could enhance Ascletis’s industry positioning and offer significant implications for stakeholders.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Advances ASC30 in U.S. Phase IIa Obesity Study
Jul 2, 2025

Ascletis Pharma Inc. has announced the dosing of the first participants in a U.S. 13-week Phase IIa study of its small molecule oral GLP-1 receptor agonist, ASC30, aimed at treating obesity and overweight individuals with weight-related comorbidities. This study is significant as it evaluates the efficacy, safety, and tolerability of ASC30, which has shown promising results in a previous Phase Ib study with a 6.5% placebo-adjusted mean body weight reduction. The successful development of ASC30 could enhance Ascletis’ position in the obesity treatment market, offering both oral and subcutaneous dosing options, with potential patent protection until 2044.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Faces Patent Challenge from CSPC Subsidiary
Jun 30, 2025

Ascletis Pharma Inc. announced that Conjupro Biotherapeutics, a subsidiary of CSPC Pharmaceutical Group, has filed a petition with the USPTO challenging the validity of one of Ascletis’ U.S. patents. This patent, crucial for the development of Ascletis’ drug candidate ASC30, is under review, and Ascletis is committed to defending its intellectual property rights. The company continues its operations unaffected while monitoring the situation closely.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Enhances Governance with New Nomination Committee Terms
Jun 27, 2025

Ascletis Pharma Inc. has amended and adopted new terms of reference for its Nomination Committee, emphasizing the importance of diversity and transparency in board appointments. This move is aimed at enhancing the company’s governance structure, potentially impacting its operational efficiency and stakeholder trust.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Begins U.S. Phase I Trial for Psoriasis Drug ASC50
Jun 18, 2025

Ascletis Pharma Inc. has announced the commencement of dosing in its U.S. Phase I clinical trial for ASC50, an oral small molecule IL-17 inhibitor aimed at treating psoriasis. This trial marks a significant step in Ascletis’ efforts to develop a potentially best-in-class treatment for psoriasis, with the study evaluating the drug’s safety, tolerability, and preliminary efficacy. The successful progression of this trial could enhance Ascletis’ position in the biopharmaceutical industry, potentially offering a new therapeutic option for psoriasis patients.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma to Present Promising Obesity Treatments at ADA Scientific Sessions
Jun 9, 2025

Ascletis Pharma Inc. announced that it will present poster presentations on its investigational drugs, ASC30 and ASC47, at the 85th Scientific Sessions of the American Diabetes Association in Chicago. ASC30 is a GLP-1R biased small molecule agonist with both oral and subcutaneous administration capabilities, protected by patents until 2044. ASC47 is a muscle-preserving weight loss drug candidate, currently in Phase I trials in combination with semaglutide, showing promising results in preclinical models. These developments highlight Ascletis’s commitment to advancing obesity treatment options, potentially strengthening its position in the pharmaceutical market.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma’s Denifanstat Achieves Breakthrough in Acne Treatment
Jun 3, 2025

Ascletis Pharma Inc. announced that its Phase III trial of Denifanstat (ASC40), a first-in-class, once-daily oral fatty acid synthase (FASN) inhibitor for acne, met all primary and secondary endpoints, demonstrating significant efficacy and a favorable safety profile. This breakthrough provides a potential new treatment for acne, showing superior effectiveness compared to existing FDA-approved treatments, and highlights Ascletis’s commitment to advancing dermatological therapies.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Faces Import Ban and Sanction in ITC Ruling
May 30, 2025

Ascletis Pharma Inc. announced a final judgment from the United States International Trade Commission regarding legal proceedings with Viking Therapeutics. The ruling imposes a seven-year prohibition on importing its drug candidates ASC41 and ASC43F into the U.S. and a joint liability payment of $567,059.85 due to procedural disputes. Despite the ruling, Ascletis states that the decision will not adversely affect its current operations as it is not pursuing these drug candidates. The company plans to seek further legal advice on appealing the judgment and remains committed to protecting its trade secrets.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Secures FDA Clearance for Psoriasis Drug Trial
May 22, 2025

Ascletis Pharma Inc. has announced that the U.S. FDA has cleared its IND application for ASC50, an oral small molecule IL-17 inhibitor, for a Phase I trial targeting mild-to-moderate plaque psoriasis. ASC50 has shown promising preclinical results, including higher drug exposure and strong efficacy, positioning it as a potential best-in-class treatment. The Phase I trial is set to begin in the third quarter of 2025, marking a significant step in Ascletis’s development pipeline.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Inc. Announces Successful AGM with Key Resolutions Passed
May 22, 2025

Ascletis Pharma Inc. held its Annual General Meeting on May 22, 2025, where all proposed resolutions were passed, including the re-election of directors and the re-appointment of KPMG as auditors. The company granted mandates to the board to issue and repurchase shares, reflecting strong shareholder support and potentially enhancing its capital management strategy.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis Pharma Initiates U.S. Clinical Study on Obesity Treatment
May 20, 2025

Ascletis Pharma Inc. has announced the dosing of the first participants in a U.S. clinical study combining their adipose-targeted small molecule THR β agonist, ASC47, with semaglutide for obesity treatment. This study aims to evaluate the safety and preliminary efficacy of ASC47, which has shown promising results in preclinical models by significantly enhancing weight loss with muscle preservation compared to semaglutide alone. The outcome of this study could potentially impact the company’s position in the obesity treatment market, with topline data expected by the fourth quarter of 2025.

The most recent analyst rating on (HK:1672) stock is a Hold with a HK$3.94 price target. To see the full list of analyst forecasts on Ascletis Pharma, Inc. stock, see the HK:1672 Stock Forecast page.

Ascletis to Present ASC47 Weight Loss Drug at European Congress
May 6, 2025

Ascletis Pharma Inc. announced that it will present findings on ASC47, its adipose-targeted, muscle-preserving weight loss drug candidate, at the 32nd European Congress on Obesity. The presentations will showcase the drug’s potential in obesity treatment, highlighting significant weight loss and muscle preservation in preliminary studies. This development could enhance Ascletis’s position in the obesity treatment market, potentially impacting stakeholders by demonstrating the efficacy of ASC47 in clinical settings.

Ascletis Pharma Announces 2025 Annual General Meeting Agenda
Apr 28, 2025

Ascletis Pharma Inc. has announced its 2025 Annual General Meeting, scheduled for May 22, 2025, in Hangzhou, China. The meeting will address several key business items, including the consideration of the company’s audited financial statements for 2024, the re-election of directors, and the re-appointment of KPMG as the auditor. Additionally, resolutions will be proposed to authorize the company’s board to manage share allotments and repurchases, potentially impacting the company’s capital structure and shareholder value.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 19, 2025