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Shanghai Henlius Biotech, Inc. Class H (HK:2696)
:2696
Hong Kong Market
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Shanghai Henlius Biotech, Inc. Class H (2696) AI Stock Analysis

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HK:2696

Shanghai Henlius Biotech, Inc. Class H

(2696)

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Neutral 61 (OpenAI - 4o)
Rating:61Neutral
Price Target:
HK$66.00
▲(8.02% Upside)
Shanghai Henlius Biotech's strong financial performance is a key strength, driven by revenue and profit growth. However, technical indicators suggest bearish momentum, and the high P/E ratio indicates potential overvaluation. The absence of a dividend yield and lack of recent earnings call data or corporate events further moderate the overall score.
Positive Factors
Revenue Growth
Consistent revenue growth over multiple years indicates strong market demand and effective product adoption, supporting long-term business expansion.
Operational Efficiency
Improved operational efficiency through higher EBIT and EBITDA margins enhances profitability and competitiveness, sustaining long-term growth.
Cash Flow Management
Strong cash flow management ensures liquidity and financial flexibility, enabling investment in growth opportunities and debt servicing.
Negative Factors
Debt Reliance
Increased reliance on debt can strain financial stability and limit flexibility, posing risks if interest rates rise or cash flows falter.
Equity Ratio Decline
A declining equity ratio indicates reduced shareholder equity relative to debt, potentially increasing financial risk and impacting investor confidence.
Absence of Dividend Yield
Lack of dividends can make the stock less attractive to income investors, potentially limiting its appeal and affecting stock demand.

Shanghai Henlius Biotech, Inc. Class H (2696) vs. iShares MSCI Hong Kong ETF (EWH)

Shanghai Henlius Biotech, Inc. Class H Business Overview & Revenue Model

Company DescriptionShanghai Henlius Biotech, Inc. Class H (2696) is a biotechnology company based in Shanghai, China, specializing in the development and commercialization of innovative monoclonal antibody therapies. The company focuses on addressing unmet medical needs in various therapeutic areas, including oncology, autoimmune diseases, and infectious diseases. Henlius aims to enhance patient access to high-quality biologics and is committed to advancing its proprietary drug candidates through rigorous clinical development and regulatory approval processes.
How the Company Makes MoneyShanghai Henlius Biotech generates revenue primarily through the sale of its monoclonal antibody products, which are marketed for various therapeutic indications. The company has established a diversified revenue model that includes direct sales of its proprietary drugs, partnerships with other pharmaceutical companies for co-development and commercialization, as well as licensing agreements that allow other firms to market its products in different regions. Significant partnerships and collaborations with global pharmaceutical companies enhance its market reach and contribute to its earnings, while also enabling shared research and development costs. Additionally, Henlius may benefit from government subsidies and grants aimed at supporting biotech innovations in China.

Shanghai Henlius Biotech, Inc. Class H Financial Statement Overview

Summary
Shanghai Henlius Biotech demonstrates strong revenue and profit growth, supported by improving operational margins and cash flow management. Despite increased reliance on debt, the company has effectively turned around its financial performance, particularly in profitability and cash flow generation.
Income Statement
82
Very Positive
Shanghai Henlius Biotech has shown a strong revenue growth trajectory with a significant increase in Total Revenue from 2019 to 2024. Gross Profit Margin has remained healthy, evidenced by a 73.1% margin in 2024. The company has successfully turned around its Net Income from a loss in previous years to a profit of 820 million in 2024, improving Net Profit Margin to 14.3%. EBIT and EBITDA margins have also improved, indicating operational efficiency gains.
Balance Sheet
75
Positive
The company maintains a moderate Debt-to-Equity Ratio of 1.21 in 2024, reflecting a balanced approach to leveraging. Return on Equity has improved to 27.2%, indicating better profitability for shareholders. However, the Equity Ratio has decreased to 28.4% in 2024, suggesting a higher reliance on debt financing compared to earlier years.
Cash Flow
78
Positive
Shanghai Henlius Biotech has shown robust improvement in Free Cash Flow, with a notable growth from negative values in earlier years to 404 million in 2024. The Operating Cash Flow to Net Income ratio of 1.51 in 2024 highlights efficient cash earnings conversion. The Free Cash Flow to Net Income ratio has also improved, indicating better cash flow management.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue5.80B5.72B5.39B3.21B1.68B587.59M
Gross Profit4.39B4.18B3.92B2.37B1.16B405.47M
EBITDA1.14B1.15B911.33M-310.61M-671.74M-814.06M
Net Income824.30M820.47M546.02M-695.26M-984.05M-993.54M
Balance Sheet
Total Assets11.55B10.60B9.90B8.92B7.17B6.44B
Cash, Cash Equivalents and Short-Term Investments972.50M772.96M1.01B680.48M742.32M1.11B
Total Debt3.67B3.65B4.09B3.68B2.62B1.83B
Total Liabilities8.14B7.58B7.71B7.29B4.88B3.24B
Stockholders Equity3.41B3.01B2.19B1.64B2.30B3.20B
Cash Flow
Free Cash Flow930.30M404.68M36.48M-383.67M-1.04B-2.12B
Operating Cash Flow990.62M1.24B1.05B981.62M90.39M-609.58M
Investing Cash Flow-123.16M-909.97M-1.00B-1.36B-1.68B-1.51B
Financing Cash Flow0.00-643.37M144.43M858.02M648.30M995.79M

Shanghai Henlius Biotech, Inc. Class H Technical Analysis

Technical Analysis Sentiment
Negative
Last Price61.10
Price Trends
50DMA
74.35
Negative
100DMA
69.44
Negative
200DMA
50.66
Positive
Market Momentum
MACD
-3.22
Positive
RSI
34.47
Neutral
STOCH
32.25
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:2696, the sentiment is Negative. The current price of 61.1 is below the 20-day moving average (MA) of 68.56, below the 50-day MA of 74.35, and above the 200-day MA of 50.66, indicating a neutral trend. The MACD of -3.22 indicates Positive momentum. The RSI at 34.47 is Neutral, neither overbought nor oversold. The STOCH value of 32.25 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:2696.

Shanghai Henlius Biotech, Inc. Class H Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
HK$34.13B38.3527.37%2.57%18.79%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
HK$24.44B-16.84-161.12%-56.94%-190.36%
43
Neutral
HK$38.97B-23.90-15.06%39.02%48.26%
40
Neutral
HK$21.75B-11.37-30.41%23.87%30.08%
40
Underperform
HK$21.45B-111.85-3.06%68.75%55.64%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:2696
Shanghai Henlius Biotech, Inc. Class H
61.10
40.15
191.65%
HK:9688
Zai Lab Ltd
17.27
-7.48
-30.22%
HK:9969
InnoCare Pharma Ltd.
14.00
6.53
87.42%
HK:1877
Shanghai Junshi Biosciences Co., Ltd. Class H
24.52
9.92
67.95%
HK:2096
Simcere Pharmaceutical Group Limited
12.36
5.80
88.41%
HK:6855
Ascentage Pharma Group International
62.30
16.85
37.07%

Shanghai Henlius Biotech, Inc. Class H Corporate Events

Shanghai Henlius Biotech Secures FDA Orphan-drug Designation for HLX43
Oct 17, 2025

Shanghai Henlius Biotech, Inc. announced that its subsidiary, Henlius USA Inc., has received Orphan-drug Designation from the U.S. FDA for HLX43, an anti-PD-L1 antibody-drug conjugate, for the treatment of thymic epithelial tumors. This designation provides the company with benefits such as tax credits, fee exemptions, and market exclusivity, which could enhance its competitive positioning in the oncology market, particularly in the U.S., where no similar PD-L1 targeting ADCs have been approved.

The most recent analyst rating on (HK:2696) stock is a Hold with a HK$77.00 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech’s HANSIZHUANG Shows Promising Results in Gastric Cancer Treatment
Oct 9, 2025

Shanghai Henlius Biotech, Inc. announced that its phase 3 clinical study of HANSIZHUANG (serplulimab injection) in combination with chemotherapy for the treatment of early-stage gastric cancer met its primary endpoint of event-free survival. This significant finding supports an early new drug application submission, indicating a promising advancement in cancer treatment. The study demonstrated a notable improvement in the pathological complete response rate and a reduction in recurrence risk, with a favorable safety profile, enhancing the company’s position in the oncology market.

The most recent analyst rating on (HK:2696) stock is a Hold with a HK$79.00 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Advances in Oncology with New Clinical Trial Approval
Sep 30, 2025

Shanghai Henlius Biotech, Inc. announced the approval of its phase 1b/2 clinical trial application for HLX43, an anti-PD-L1 antibody-drug conjugate, in combination with HLX07 for treating advanced/metastatic solid tumors. This approval by the National Medical Products Administration marks a significant step in the company’s clinical development efforts, potentially enhancing its market position in oncology therapeutics. The trial’s previous data demonstrated promising results, showing high response rates and good safety profiles, especially in patients with advanced non-small cell lung cancer, indicating a positive outlook for stakeholders.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech’s HLX13 Receives FDA Approval for Clinical Trial
Sep 29, 2025

Shanghai Henlius Biotech, Inc. announced that its investigational new drug application for HLX13, a biosimilar of Ipilimumab, was approved by the FDA for a phase 1 clinical trial as a first-line treatment for unresectable hepatocellular carcinoma. This approval marks a significant step for the company in expanding its clinical trials internationally, potentially enhancing its market position in the oncology sector and providing new treatment options for various cancers.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Initiates Global Trial for Cancer Treatment Biosimilar
Sep 26, 2025

Shanghai Henlius Biotech, Inc. has initiated an international multi-center phase 1 clinical trial for HLX17, a biosimilar of pembrolizumab, in patients with multiple resected solid tumors in mainland China. This trial aims to evaluate the pharmacokinetic profile, efficacy, safety, and immunogenicity of HLX17 compared to KEYTRUDA, with plans to expand the trial to the United States, Europe, and Australia. The announcement marks a significant step in the company’s efforts to position itself in the global oncology market, leveraging the high global sales of pembrolizumab, which reached approximately USD 32.056 billion in 2024.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Gains EU Approval for Osteoporosis Treatments
Sep 19, 2025

Shanghai Henlius Biotech, Inc. announced that the European Commission has approved the marketing authorization applications for two of its products, BILDYOS® and BILPREVDA®, for the treatment of osteoporosis and other bone-related conditions in the EU and EEA countries. This approval is based on extensive comparative studies demonstrating the similarity of HLX14 to the reference product, Prolia®, and marks a significant step in the company’s global expansion strategy, potentially impacting its market positioning and stakeholder interests.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Advances HLX43 Clinical Trials for Lung Cancer
Sep 18, 2025

Shanghai Henlius Biotech, Inc. has announced the dosing of the first patient in Australia in its international multicentre phase 2 clinical study of HLX43, an anti-PD-L1 antibody-drug conjugate, for advanced non-small cell lung cancer (NSCLC). The study, also ongoing in mainland China and the United States, aims to evaluate the efficacy and safety of HLX43. Previous phase 1 results demonstrated promising response rates and safety profiles, particularly in patients with advanced tumors who have not responded to other treatments, indicating potential significant impact on the company’s market positioning in oncology therapeutics.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech’s HLX17 Receives FDA Approval for Clinical Trials
Sep 8, 2025

Shanghai Henlius Biotech, Inc. announced that the U.S. FDA has approved the investigational new drug application for HLX17, a biosimilar of pembrolizumab, for phase 1 clinical trials. This approval marks a significant step for the company as it aims to conduct international multi-center trials, potentially enhancing its position in the oncology market, where pembrolizumab sales reached approximately USD 32.056 billion in 2024.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Receives FDA Approval for Two Biosimilars
Sep 1, 2025

Shanghai Henlius Biotech, Inc. has announced that the U.S. FDA has approved two of its biosimilar products, BILDYOS® and BILPREVDA®, for eight indications related to osteoporosis and other bone conditions. This approval is based on comprehensive studies demonstrating the biosimilars’ similarity to the reference products in terms of quality, safety, and efficacy. The approval is expected to enhance the company’s market position and expand its global reach, particularly through its partnership with Organon LLC for commercialization outside of China.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Confirms Leadership Continuity with Board Re-appointments
Aug 29, 2025

Shanghai Henlius Biotech, Inc. announced the results of its 2025 third extraordinary general meeting, where key resolutions regarding the re-appointment of board members and executives were approved. The re-appointments include the chairman of the board, chairman of the board of supervisors, and the chief executive officer, which are expected to provide continuity in leadership and strategic direction for the company.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Announces Board Composition and Roles
Aug 29, 2025

Shanghai Henlius Biotech, Inc. has announced the composition of its board of directors and their respective roles within the company. This announcement provides clarity on the leadership structure, which may impact the company’s strategic direction and governance, potentially influencing stakeholder confidence and market positioning.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Grants Options and RSUs to Boost Performance
Aug 29, 2025

Shanghai Henlius Biotech, Inc. announced the granting of 67,500 options and 87,500 restricted stock units (RSUs) to selected participants under its Share Option and RSU Schemes. This strategic move aims to align employee incentives with the company’s performance goals, potentially enhancing its market position and operational efficiency. The vesting of these options is tied to specific performance targets, including financial and R&D indicators, as well as market capitalization objectives, reflecting the company’s commitment to driving growth and value for its stakeholders.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$97.75 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Reports Growth and Expands Global Reach in 2025
Aug 25, 2025

Shanghai Henlius Biotech, Inc. reported a modest increase in total revenue and profit for the first half of 2025, driven by drug sales, R&D services, and license income. The company’s international strategy has led to significant growth in overseas product sales, particularly in the United States, enhancing its global profitability. The company has successfully expanded its product approvals across multiple countries, with notable achievements in the marketing of its anti-PD-1 monoclonal antibody, HANSIZHUANG, and the biosimilar HANQUYOU. Strategic licensing agreements further bolster its international commercial footprint.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$77.00 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Advances HLX43 Clinical Trials in the US
Aug 22, 2025

Shanghai Henlius Biotech, Inc. announced the dosing of the first patient in the United States for its international multi-center phase 2 clinical study of HLX43, targeting advanced non-small cell lung cancer. This study, which is also ongoing in China, aims to assess the efficacy and safety of HLX43, with plans to expand trials to Australia, Japan, and other countries. The announcement marks a significant step in the company’s efforts to advance its oncology pipeline and strengthen its position in the global biotechnology market.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$77.00 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Clarifies Member Register Closure Procedures
Aug 15, 2025

Shanghai Henlius Biotech, Inc. has issued a clarification announcement regarding the closure of its register of members, specifying the requirements for lodging transfer documents and share certificates for registration by August 26, 2025. This announcement ensures that shareholders are informed of the necessary procedures, potentially impacting shareholder transactions and company operations.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$61.98 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech’s New Drug Application for HLX04-O Accepted by NMPA
Aug 13, 2025

Shanghai Henlius Biotech, Inc. announced that its New Drug Application for HLX04-O, a recombinant anti-VEGF humanized monoclonal antibody injection for treating wet age-related macular degeneration (wAMD), has been accepted by China’s National Medical Products Administration. This development is significant as it marks a step forward in the company’s efforts to provide new treatment options for wAMD, a condition with limited approved treatments in China. The acceptance of the NDA follows successful clinical trials demonstrating the drug’s non-inferiority to existing treatments and its favorable safety profile, potentially positioning Henlius as a key player in the ophthalmic drug market.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$61.98 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Announces Extraordinary General Meeting for Key Resolutions
Aug 12, 2025

Shanghai Henlius Biotech, Inc. has announced an extraordinary general meeting to be held on August 29, 2025, to discuss and approve several resolutions. These include the re-appointment and appointment of directors and shareholder representative supervisors, as well as proposed amendments to the Rules of Procedures for the General Meeting, the Board, and the Board of Supervisors. The meeting’s outcomes could impact the company’s governance structure and operational procedures, potentially influencing its strategic direction and stakeholder engagement.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$61.98 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Announces New Board Appointments
Aug 8, 2025

Shanghai Henlius Biotech, Inc. has announced the proposed re-appointment and appointment of directors and supervisors for the fourth session of its board. This includes the re-appointment of several current directors and the introduction of new members, reflecting the company’s strategic focus on maintaining a robust governance structure. The decisions are set to be approved at the upcoming Extraordinary General Meeting (EGM), which underscores the company’s commitment to strong leadership and oversight, potentially impacting its market positioning and stakeholder confidence.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$61.98 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Biotech Gains FDA Approval for HLX43 Clinical Trial
Aug 7, 2025

Shanghai Henlius Biotech, Inc. has announced that its anti-PD-L1 antibody-drug conjugate, HLX43, has received approval from the U.S. FDA to begin a phase 1 clinical trial for the treatment of thymic carcinoma. This approval marks a significant step in the company’s efforts to advance its oncology pipeline, with plans to conduct further clinical studies in multiple countries. The approval positions Henlius as a key player in the ADC market, particularly as no ADC targeting PD-L1 has been approved globally yet, potentially enhancing its market presence and offering new treatment options for patients with advanced cancers.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$61.98 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Shanghai Henlius Initiates Phase 2 Study for HLX79 in Glomerulonephritis Treatment
Aug 6, 2025

Shanghai Henlius Biotech, Inc. announced the commencement of a Phase 2 clinical study for HLX79, a human sialidase fusion protein, in combination with HANLIKANG, for treating active glomerulonephritis in Mainland China. This study aims to evaluate the safety, tolerability, and efficacy of the combination treatment, potentially enhancing B lymphocyte depletion and benefiting patients with autoimmune diseases. The development of HLX79 is part of a global collaboration with Palleon Pharmaceuticals, with Shanghai Henlius holding exclusive rights in China.

The most recent analyst rating on (HK:2696) stock is a Buy with a HK$61.98 price target. To see the full list of analyst forecasts on Shanghai Henlius Biotech, Inc. Class H stock, see the HK:2696 Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 06, 2025