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Shanghai Junshi Biosciences Co., Ltd. Class H (HK:1877)
:1877

Shanghai Junshi Biosciences Co., Ltd. Class H (1877) AI Stock Analysis

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HK:1877

Shanghai Junshi Biosciences Co., Ltd. Class H

(1877)

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Underperform 38 (OpenAI - 4o)
Rating:38Underperform
Price Target:
HK$21.50
▼(-7.49% Downside)
Shanghai Junshi Biosciences faces significant financial challenges, with negative profitability and cash flow issues being the most impactful factors. The technical analysis indicates a bearish trend, and the valuation is unattractive due to a negative P/E ratio. These factors collectively result in a low overall stock score.
Positive Factors
Product Efficacy
The positive results from JUPITER-02 and JUPITER-06 trials demonstrate the efficacy of Junshi's therapies, enhancing its competitive position in oncology.
Global Market Expansion
Global approval of torpalimab expands Junshi's market reach, potentially increasing revenue streams and strengthening its international presence.
Revenue Growth
Consistent revenue growth indicates strong demand for Junshi's products and effective market strategies, supporting long-term business sustainability.
Negative Factors
Profitability Challenges
Ongoing profitability issues highlight operational inefficiencies, which could hinder reinvestment and growth unless addressed strategically.
Cash Flow Issues
Negative cash flows indicate potential liquidity constraints, affecting Junshi's ability to fund operations and invest in future growth initiatives.
Shareholder Value Concerns
Negative ROE suggests inefficiencies in generating shareholder value, which may impact investor confidence and long-term capital raising abilities.

Shanghai Junshi Biosciences Co., Ltd. Class H (1877) vs. iShares MSCI Hong Kong ETF (EWH)

Shanghai Junshi Biosciences Co., Ltd. Class H Business Overview & Revenue Model

Company DescriptionShanghai Junshi Biosciences Co., Ltd., a biopharmaceutical company, engages in the discovery, development, and commercialization of various drugs in the therapeutic areas of oncology, metabolic, autoimmune, neurologic, and infectious diseases in the People's Republic of China. The company offers JS001, a recombinant humanized anti-PD-1 monoclonal antibody under the trade name of TUOYI for the indication of melanoma, mucosal melanoma, soft tissue sarcoma, nasopharyngeal carcinoma, urothelial carcinoma, non-small cell lung carcinoma, triple negative breast carcinoma, esophageal squamous cell carcinoma, and hepatocellular carcinoma. It is also developing UBP1211, a biosimilar of Humira for the treatment of rheumatoid arthritis, ankylosing spondylitis, and psoriasis; JS002, a recombinant humanized anti-PCSK9 monoclonal antibody for treating hyperlipidemia; UBP1213, a recombinant humanized anti-BLyS monoclonal antibody for injection. In addition, the company is developing JS501, a biosimilar of Avastin; and JS003, a recombinant humanized anti-PD-L1 monoclonal antibody for injection; JS101, a pan-CDK inhibitor; TAB004/JS004, a recombinant humanized anti-BTLA monoclonal antibody for injection; and JS005, a recombinant humanized anti-IL-17A monoclonal antibody for injection. It has an agreement with Eli Lilly and Company to co-develop therapeutic antibodies for the potential prevention and treatment of COVID-19, the disease caused by the SARS-CoV-2 novel coronavirus as well as Coherus Biosciences, Inc. for the development and commercialization of toripalimab, Junshi Biosciences' anti-PD-1 antibody. Shanghai Junshi Biosciences Co., Ltd. was founded in 2012 and is headquartered in Shanghai, People's Republic of China.
How the Company Makes MoneyJunshi Biosciences generates revenue primarily through the commercialization of its proprietary biopharmaceutical products, which are sold in both domestic and international markets. The company earns money from product sales, including its flagship monoclonal antibody therapies, and may also receive milestone payments and royalties from partnerships and collaborations with other pharmaceutical companies. Additionally, Junshi Biosciences may engage in licensing agreements that provide upfront payments and ongoing royalties. The company’s strategic partnerships with global biopharmaceutical firms further bolster its revenue potential by facilitating access to larger markets and enhancing its product development capabilities.

Shanghai Junshi Biosciences Co., Ltd. Class H Financial Statement Overview

Summary
The company is experiencing financial instability with persistent losses and negative cash flows, despite a solid equity position. The volatile revenue pattern and negative EBIT and net income margins highlight ongoing profitability challenges.
Income Statement
35
Negative
The company shows a volatile revenue pattern with a significant decline in the latest year. Gross profit margin is healthy, but persistently negative EBIT and net income margins highlight ongoing profitability challenges. Revenue growth has been inconsistent, indicating market or product-related uncertainties.
Balance Sheet
45
Neutral
The balance sheet is relatively stable with a strong equity position. The debt-to-equity ratio remains manageable, suggesting moderate leverage. However, there is a noticeable decline in total assets over recent years, which warrants close monitoring.
Cash Flow
30
Negative
Operating cash flows have been consistently negative, reflecting challenges in generating cash from core operations. Free cash flow remains negative, though there is some improvement in the latest year. The cash flow to net income ratios indicate inefficiencies in converting income into cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.54B1.95B1.50B1.45B4.02B1.59B
Gross Profit2.08B1.54B835.26M927.21M2.77B1.22B
EBITDA-745.31M-935.50M-2.16B-2.52B-476.32M-1.58B
Net Income-966.82M-1.28B-2.28B-2.39B-718.56M-1.67B
Balance Sheet
Total Assets12.77B10.80B11.36B12.58B11.05B8.01B
Cash, Cash Equivalents and Short-Term Investments3.57B2.93B3.78B6.00B3.50B3.39B
Total Debt3.92B2.93B1.79B1.32B628.20M850.78M
Total Liabilities5.89B4.85B4.02B2.78B2.72B2.17B
Stockholders Equity6.79B5.86B7.17B9.50B7.96B5.84B
Cash Flow
Free Cash Flow-1.28B-2.12B-2.85B-2.17B-1.53B-2.09B
Operating Cash Flow-681.74M-1.43B-2.01B-1.78B-641.90M-1.50B
Investing Cash Flow-745.27M-892.78M-892.42M-467.62M-1.88B-697.98M
Financing Cash Flow1.70B1.02B681.04M4.64B2.67B4.41B

Shanghai Junshi Biosciences Co., Ltd. Class H Technical Analysis

Technical Analysis Sentiment
Negative
Last Price23.24
Price Trends
50DMA
25.16
Negative
100DMA
28.31
Negative
200DMA
23.46
Negative
Market Momentum
MACD
-0.70
Positive
RSI
33.80
Neutral
STOCH
18.55
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:1877, the sentiment is Negative. The current price of 23.24 is below the 20-day moving average (MA) of 23.91, below the 50-day MA of 25.16, and below the 200-day MA of 23.46, indicating a bearish trend. The MACD of -0.70 indicates Positive momentum. The RSI at 33.80 is Neutral, neither overbought nor oversold. The STOCH value of 18.55 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:1877.

Shanghai Junshi Biosciences Co., Ltd. Class H Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
66
Neutral
HK$32.96B36.9727.37%2.57%18.79%
53
Neutral
HK$9.97B40.6813.34%206.58%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
HK$20.98B-14.30-161.12%-56.94%-190.36%
42
Neutral
HK$15.05B-9.08-30.41%23.87%30.08%
40
Neutral
HK$47.89B-40.63-39.64%46.14%39.56%
38
Underperform
HK$36.45B-21.91-15.06%38.56%48.26%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:1877
Shanghai Junshi Biosciences Co., Ltd. Class H
23.24
11.00
89.87%
HK:9688
Zai Lab Ltd
13.80
-6.80
-33.01%
HK:9966
Alphamab Oncology
10.67
7.21
208.38%
HK:9995
RemeGen Co. Ltd. Class H
78.30
63.54
430.49%
HK:2696
Shanghai Henlius Biotech, Inc. Class H
60.55
36.65
153.35%
HK:6855
Ascentage Pharma Group International
56.05
13.10
30.50%

Shanghai Junshi Biosciences Co., Ltd. Class H Corporate Events

Shanghai Junshi Biosciences Expands Drug Coverage in China’s National Reimbursement List
Dec 7, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that two new indications for its products, Toripalimab Injection (TUOYI) and Ongericimab Injection (JUNSHIDA), have been added to China’s National Reimbursement Drug List (NRDL) effective January 2026. This inclusion marks a significant milestone for the company, as all 12 indications of TUOYI are now covered, making it the only anti-PD-1 monoclonal antibody in the NRDL for renal cancer, TNBC, and melanoma. JUNSHIDA’s inclusion is notable as it is the only domestic PCSK9-targeted drug for statin-intolerant patients in the NRDL, enhancing the company’s market positioning and potential stakeholder benefits.

Shanghai Junshi Biosciences’ New Drug Application for Roconkibart Injection Accepted
Dec 5, 2025

Shanghai Junshi Biosciences Co., Ltd. announced the acceptance of its new drug application for Roconkibart Injection by the National Medical Products Administration. This drug, aimed at treating moderate to severe plaque psoriasis, has shown significant efficacy in clinical trials and represents a potential advancement in the treatment of autoimmune diseases, enhancing the company’s position in the pharmaceutical industry.

Shanghai Junshi Biosciences Announces Shareholding Reduction
Dec 4, 2025

Shanghai Junshi Biosciences Co., Ltd. announced a reduction in shareholding by Shanghai Tanying Investment Partnership, which previously held over 6.96% of the company’s total share capital. This decision follows the maturity of the fund and liquidity arrangements, impacting the company’s shareholder structure and potentially influencing market perceptions of its financial strategy.

Shanghai Junshi Biosciences Announces Shareholder Equity Adjustment
Dec 3, 2025

Shanghai Junshi Biosciences Co., Ltd. announced a change in equity holdings, with shareholders holding more than 5% of shares reducing their stake from 5.0051% to 4.7129%. This change does not breach any commitments or trigger a mandatory tender offer obligation, indicating a strategic adjustment in shareholder composition without significant operational impact.

Shanghai Junshi Biosciences Implements New Cash Management Strategy
Nov 27, 2025

Shanghai Junshi Biosciences Co., Ltd. has announced a new cash management strategy involving the use of temporarily idle proceeds to purchase principal guaranteed investment products with high security and good liquidity. This move aims to improve the efficiency of fund utilization without affecting the company’s ongoing investment plans, and it has been approved by the Board of Directors, with a validity of 12 months.

Shanghai Junshi Biosciences’ JS001sc Achieves Key Milestone in NSCLC Treatment
Nov 24, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that its phase III clinical study of JS001sc, a subcutaneous injection formulation for the first-line treatment of non-squamous non-small cell lung cancer (NSCLC), has met its primary endpoints. This development marks a significant step in providing a more convenient administration method for immunotherapy, potentially enhancing patient experience and positioning the company as a leader in domestic anti-PD-1 monoclonal antibody treatments. The company plans to submit a new drug application to regulatory authorities, which could impact its market presence and offer new options for NSCLC patients.

Shanghai Junshi Biosciences Completes Registration for 2025 A Share Options
Nov 14, 2025

Shanghai Junshi Biosciences Co., Ltd. has completed the registration of its First Grant of A Share Options under the 2025 A Share Option Incentive Scheme, following shareholder approval. The scheme involves 24,700,000 A Share Options granted to 226 participants, including employees and a substantial shareholder, with specific vesting and exercise conditions outlined for the options. This initiative is expected to enhance stakeholder engagement and align employee interests with company growth objectives.

Shanghai Junshi Biosciences Chairman to Increase Shareholding
Nov 10, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that its chairman, Mr. Xiong Jun, plans to increase his shareholding in the company by at least RMB100 million, with a minimum of RMB50 million allocated to A shares. As of the announcement date, Mr. Xiong Jun has already acquired 100,000 A shares, representing 0.01% of the company’s total share capital, through the Shanghai Stock Exchange. This move reflects confidence in the company’s future prospects, although the plan’s completion is subject to market conditions and other unpredictable risk factors.

Shanghai Junshi Biosciences Reports Strong Q3 2025 Financial Performance
Oct 28, 2025

Shanghai Junshi Biosciences Co., Ltd. has released its unaudited financial results for the third quarter of 2025, reporting a significant increase in operating income. The company’s revenue rose by 31.40% during the reporting period and by 42.06% from the beginning of the year, highlighting its strong market performance and potential positive impact on its stakeholders.

Shanghai Junshi Biosciences’ Subsidiary Passes FDA Inspection, Bolstering U.S. Market Expansion
Oct 22, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that its wholly-owned subsidiary, Suzhou Union Biopharm Co., Ltd., has successfully passed an unannounced FDA on-site inspection for Current Good Manufacturing Practice (CGMP) compliance. This achievement marks the second successful FDA inspection for Suzhou Union, reinforcing the company’s high production standards and supporting its expansion strategy in the U.S. market. The successful inspection is expected to positively impact the company’s operations and strengthen its position in the global pharmaceutical industry.

Shanghai Junshi Biosciences Announces 2025 Q3 Results Briefing
Oct 21, 2025

Shanghai Junshi Biosciences Co., Ltd. announced the convening of its 2025 third quarterly results briefing, scheduled for October 29, 2025. The briefing aims to provide investors with a comprehensive understanding of the company’s operating results and financial status for the third quarter of 2025, facilitating communication between the company and its stakeholders.

Shanghai Junshi Biosciences Gains FDA Approval for JS207 Clinical Study in NSCLC
Oct 16, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that the U.S. FDA has approved its investigational new drug application for a phase II/III clinical study of JS207, a recombinant humanized anti-PD-1/VEGF bispecific antibody, for the neoadjuvant treatment of non-small cell lung cancer (NSCLC) patients. This approval marks a significant step for the company as it positions JS207 as a potential new treatment option for NSCLC, addressing unmet clinical needs and potentially improving patient outcomes in a highly prevalent and deadly cancer type.

Shanghai Junshi Biosciences to Review Nine-Month Financial Results
Oct 15, 2025

Shanghai Junshi Biosciences Co., Ltd. has announced that its board of directors will meet on October 28, 2025, to review and approve the company’s unaudited financial results for the nine months ending September 30, 2025. This meeting is significant as it will provide insights into the company’s financial health and performance, potentially impacting its market positioning and stakeholder confidence.

Junshi Biosciences Chairman Plans Significant Shareholding Increase
Oct 10, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that its chairman, Mr. Xiong Jun, plans to increase his shareholding in the company by at least RMB100 million, with a minimum of RMB50 million allocated to A shares. As of October 2025, the shareholding increase plan has reached its midpoint, but due to various factors such as reporting windows and funding arrangements, the increase has not yet been completed. Mr. Xiong Jun intends to continue with the shareholding increase plan as opportunities arise, which may impact the company’s market position and shareholder confidence.

Shanghai Junshi Biosciences Adjusts 2025 A Share Option Incentive Scheme
Sep 29, 2025

Shanghai Junshi Biosciences Co., Ltd. announced adjustments to its 2025 A Share Option Incentive Scheme, reducing the number of participants from 251 to 235 and the total A Share Options from 26,175,871 to 25,965,871. These changes, approved by the Board of Directors and the Remuneration and Appraisal Committee, are not expected to materially impact the company’s financial condition or operations, and do not require further shareholder approval.

Shanghai Junshi Biosciences Announces Key Board Changes
Sep 29, 2025

Shanghai Junshi Biosciences Co., Ltd. announced the election of Dr. Yang Jin as an Independent Non-executive Director, effective September 29, 2025. This change also affects the composition of the Remuneration and Appraisal Committee and the Nomination Committee, with Dr. Yang Jin and Ms. Lu Kun taking new roles. The abolishment of the Board of Supervisors marks a significant shift in the company’s governance structure, potentially impacting its operational and strategic direction.

Shanghai Junshi Biosciences Passes Key Resolutions at 2025 EGM
Sep 29, 2025

Shanghai Junshi Biosciences Co., Ltd. announced the successful passing of all resolutions during its 2025 first extraordinary general meeting. The meeting saw significant participation from shareholders, with a notable percentage of shares represented. Key resolutions included the election of an Independent Non-executive Director and amendments to internal management policies, reflecting the company’s strategic focus on governance and operational efficiency.

Shanghai Junshi Biosciences Announces Strategic Capital Increase Agreement
Sep 29, 2025

Shanghai Junshi Biosciences Co., Ltd. has announced a capital increase agreement involving its non-wholly owned subsidiary, JunTop Biosciences, and Shanghai Tanying Investment Partnership. This transaction, which is classified as a related party transaction under PRC laws, does not constitute a connected transaction under Hong Kong’s Listing Rules. The agreement signifies a strategic move to bolster financial resources, potentially enhancing the company’s market position and operational capabilities.

Shanghai Junshi Biosciences Announces Board Composition and Committee Roles
Sep 29, 2025

Shanghai Junshi Biosciences Co., Ltd. has announced the composition of its board of directors and their roles within the company. This update includes the appointment of executive, non-executive, and independent non-executive directors, along with the establishment of five committees to oversee various aspects of the company’s governance and strategic direction.

Shanghai Junshi Biosciences Adjourns 2025 EGM to Discuss H Share Options
Sep 15, 2025

Shanghai Junshi Biosciences Co., Ltd. has announced the adjournment of its 2025 first extraordinary general meeting (EGM) to 29 September 2025. The meeting will address special resolutions regarding the proposed grant of H Share Options to Mr. Zhang Zhuobing and Dr. Yao Sheng, contingent upon the adoption of the 2025 H Share Option Incentive Scheme. This development is significant for stakeholders as it reflects the company’s ongoing efforts to incentivize key personnel, potentially impacting its strategic direction and market positioning.

Shanghai Junshi Biosciences Reschedules Extraordinary General Meeting
Sep 15, 2025

Shanghai Junshi Biosciences Co., Ltd. has announced the adjournment of its Extraordinary General Meeting (EGM) initially scheduled for September 26, 2025, now rescheduled to September 29, 2025. This postponement is to provide shareholders with additional time to consider special resolutions. The company has issued a supplemental proxy form and circular to guide shareholders on the new voting procedures, ensuring clarity and compliance in the decision-making process.

Shanghai Junshi Biosciences Announces Change in Shareholder Equity
Sep 12, 2025

Shanghai Junshi Biosciences Co., Ltd. announced a change in equity holdings, where the shareholders holding more than 5% of the company’s shares, including Shanghai Tanying Investment Partnership and its concerted parties, have reduced their total equity proportion from 8.96% to 7.91%. This change does not breach any commitments or trigger a mandatory tender offer obligation, indicating a strategic adjustment in shareholder structure without significant implications for the company’s operational commitments or market positioning.

Shanghai Junshi Biosciences’ JS005 Achieves Key Milestone in Psoriasis Treatment
Sep 7, 2025

Shanghai Junshi Biosciences Co., Ltd. announced that its anti-IL-17A monoclonal antibody, JS005, has successfully met the primary and secondary endpoints in a Phase III clinical study for treating moderate to severe plaque psoriasis. This achievement marks a significant advancement in the company’s product pipeline, potentially enhancing its market position in the autoimmune disease treatment sector. The study demonstrated that JS005 significantly improved psoriasis symptoms compared to a placebo, with good safety results, and the company plans to submit a new drug application soon.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 18, 2025