Ascletis Pharma, Inc.
Ascletis Pharma Inc. is a biotechnology firm engaged in the discovery, development, manufacturing, marketing, and global distribution of pharmaceutical products, with operations spanning Mainland China and international markets. The company's commercialized offerings include the Ritonavir oral tablet, a pharmacokinetic enhancer for various oral antiviral drugs targeting viral proteases and a key component of the approved antiviral Paxlovid. It also provides ASCLEVIR and GANOVO for the management of Hepatitis C virus infections. Its robust development pipeline features ASC22, being advanced for chronic hepatitis B (CHB) and as a potential functional cure for human immunodeficiency virus; ASC42, which also targets a functional cure for CHB, in addition to primary biliary cholangitis; and ASC10 and ASC11 for COVID-19. Ascletis is significantly invested in non-alcoholic steatohepatitis (NASH) research with a range of candidates such as ASC40, ASC41, ASC42, ASC43F FDC, ASC44F FDC, and ASC45F FDC. Furthermore, its oncology programs encompass ASC40 for recurrent glioblastoma, drug-resistant breast cancer, and KRAS mutant non-small cell lung cancer, alongside ASC61 and ASC63 for advanced solid tumors, and ASC60 for general solid tumor treatment. Interestingly, ASC40 is also being explored for acne. Established in 2013, Ascletis Pharma Inc. is headquartered in Hangzhou, People's Republic of China.