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Roche Holding (CH:ROG)
:ROG

Roche Holding AG (ROG) AI Stock Analysis

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Roche Holding AG

(OTC:ROG)

Rating:74Outperform
Price Target:
CHF294.00
â–²(13.08%Upside)
Roche Holding AG's stock score reflects a strong financial performance and positive earnings call, highlighting significant growth in sales and operating profit. The company's robust cash flow management and strategic initiatives position it well for future stability. However, technical analysis indicates a lack of clear trend direction, and the relatively high P/E ratio suggests potential overvaluation. Overall, the stock presents a balanced outlook with attractive income prospects for investors.
Positive Factors
Investment
Roche announced a $50 billion investment in the US for Pharma and diagnostics over the next five years, including research and development sites and new manufacturing facilities.
Market Share
Roche continues to take market share in the US across various indications with increasing percentages.
Product Development
Another high profile phase 2 asset is now moving into phase 3.
Negative Factors
Competitive Pressure
Long-term obesity optionality could be somewhat overshadowed by increasing amylin competition.
Financial Performance
The mid-term earnings growth outlook for Roche is projected at 4%, which is lower compared to sector peers at 8%.
Sales Performance
A more challenging US market for Vabysmo drives FY25 sales growth closer to 18% YoY, compared to the pre-Q1 consensus of around 33% growth.

Roche Holding AG (ROG) vs. iShares MSCI Switzerland ETF (EWL)

Roche Holding AG Business Overview & Revenue Model

Company DescriptionRoche Holding AG is a global healthcare company headquartered in Basel, Switzerland, operating primarily in the pharmaceuticals and diagnostics sectors. It is renowned for its focus on advancing science to improve people's lives, offering a wide range of products, including innovative medicines and diagnostic tests. Roche is a leader in personalized healthcare, aiming to provide targeted treatments tailored to patients' specific needs.
How the Company Makes MoneyRoche Holding AG generates revenue through the development, manufacturing, and sale of pharmaceutical products and diagnostic solutions. The company operates two primary divisions: Pharmaceuticals and Diagnostics. The Pharmaceuticals division is the main revenue driver, offering prescription medicines in areas such as oncology, immunology, infectious diseases, ophthalmology, and neuroscience. Roche's Diagnostics division provides a broad array of testing solutions, including in vitro diagnostics, molecular diagnostics, and tissue-based cancer diagnostics. Furthermore, Roche benefits from strategic partnerships and collaborations, enhancing its research and development capabilities and expanding its market reach. The company also invests heavily in research and development to innovate and maintain a competitive edge in the healthcare industry.

Roche Holding AG Earnings Call Summary

Earnings Call Date:Jan 30, 2025
(Q4-2024)
|
% Change Since: -4.34%|
Next Earnings Date:Jul 24, 2025
Earnings Call Sentiment Positive
Roche demonstrated strong financial performance in 2024 with significant growth in sales, operating profit, and cash flow. The pharmaceutical and diagnostics divisions both showed robust growth, supported by strategic acquisitions and new product launches. However, challenges such as the decline in COVID-19 sales, impairments affecting net income, and market challenges in China were notable concerns. Overall, the highlights substantially outweigh the lowlights.
Q4-2024 Updates
Positive Updates
Strong Financial Performance
Group sales grew 7%, with the base business growing 9%, pharma 9%, and diagnostics 8%. Core operating profit increased by 14%, with a core operating margin up 2.1 percentage points. Operating free cash flow increased by 34% to CHF21.2 billion.
Pharmaceutical Achievements
Pharma sales grew 8% to CHF46.2 billion, driven by Vabysmo, Phesgo, and Ocrevus, among others. The company launched two new medicines, PiaSky and Itovebi, in 2024.
Diagnostics Growth
Diagnostics division reported 4% sales growth, with a strong base business growth of 8% driven by immunodiagnostics and clinical chemistry.
Pipeline and Product Launches
Roche achieved several key milestones, including EU approval for Vabysmo pre-filled syringe and positive readouts for trontinemab and NXT007. Launches included Mass Spectrometry system and cobas 6800/8800 version 2.
Strategic Acquisitions and Partnerships
Acquisition of Poseida to expand the allogeneic CAR-T portfolio, introducing potential treatments for oncology and autoimmune diseases.
Negative Updates
COVID-19 Sales Decline
Final impact of COVID-19 sales reduction in 2024 amounted to CHF1.1 billion, aligning with guidance but marking the end of a significant revenue stream.
Challenges in China
Diagnostics sales in China were impacted by volume-based procurement and reimbursement reductions, leading to a lower growth projection for 2025.
Impairments Affecting Net Income
IFRS net income decreased by 19% due to two major impairments totaling CHF3.9 billion, reflecting unmet expectations of acquired assets.
Patent and Biosimilar Concerns
Continued concern over patent expirations and biosimilar competition, notably impacting Actemra and Ocrevus in the future.
Company Guidance
During the call, Roche Group provided detailed guidance on its fiscal 2024 performance, highlighting several key metrics. The company achieved an overall group sales growth of 7%, with the base business excluding COVID-19 impacts growing by an impressive 9%. The pharmaceutical division reported a 9% increase, and the diagnostics division saw an 8% rise. Roche confirmed that the final impact of COVID-19 sales reduction was CHF1.1 billion, aligning with their initial guidance. The loss of exclusivity (LOE) impact was CHF1 billion, slightly better than expected. The core operating profit grew by 14%, and the group core operating margin increased by 2.1 percentage points. Additionally, core EPS growth was 12%, excluding tax effects, or 7% when including them. Operating free cash flow surged by 34% to CHF21.2 billion, reflecting strong financial health. Looking forward, Roche anticipates mid-single digit group sales growth and high-single digit core EPS growth for 2025, despite an expected LOE impact of CHF1.2 billion. The company also plans to continue its tradition of increasing dividends, marking the 38th consecutive year of growth in this area.

Roche Holding AG Financial Statement Overview

Summary
Roche Holding AG demonstrates solid financial health with strong cash flow generation and stable income statement metrics. However, the declining net profit margin and return on equity indicate potential pressures on profitability and efficiency. The balance sheet remains robust, with moderate leverage and improved equity financing. Overall, while the company faces some profitability challenges, its strong cash flow positions it well for future stability.
Income Statement
75
Positive
Roche Holding AG's income statement shows a stable gross profit margin of approximately 74% for 2024. However, the net profit margin decreased from 19% in 2023 to 13% in 2024, indicating a reduction in profitability. Revenue growth was modest at 3.2% in 2024 compared to 2023, and EBIT margin also declined to 21.5% from 25.5% in 2023. EBITDA margin remains strong at 26.6% but has decreased from previous years. Overall, the company maintains strong profitability metrics, although there are signs of margin pressure.
Balance Sheet
70
Positive
The balance sheet reflects a debt-to-equity ratio of 1.14 in 2024, indicating moderate leverage. Return on equity stands at 26%, which is a decline from 39% in 2023, suggesting reduced efficiency in using equity to generate profits. Equity ratio improved to 31.2% from 32.4% in 2023, indicating a slight improvement in asset financing through equity. While the company remains financially stable, the decline in ROE is a concern.
Cash Flow
80
Positive
Roche's cash flow statement shows strong free cash flow generation with a growth rate of 31.8% in 2024. Operating cash flow to net income ratio is robust at 2.43, reflecting strong cash earnings relative to net income. Free cash flow to net income ratio also improved to 1.82, indicating efficient cash utilization. These metrics suggest excellent cash flow management despite the decline in net income.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue62.40B60.44B63.28B62.80B58.32B
Gross Profit46.11B44.08B44.44B43.10B41.97B
EBITDA16.62B18.41B20.80B22.19B22.97B
Net Income8.28B11.50B12.42B13.93B14.29B
Balance Sheet
Total Assets101.80B90.47B88.15B92.32B86.14B
Cash, Cash Equivalents and Short-Term Investments17.32B10.51B9.77B13.03B12.33B
Total Debt36.35B30.78B26.54B32.55B15.41B
Total Liabilities65.64B57.20B56.14B63.97B46.37B
Stockholders Equity31.77B29.32B27.99B24.49B36.34B
Cash Flow
Free Cash Flow15.09B11.45B13.34B16.02B11.47B
Operating Cash Flow20.09B16.09B17.89B20.57B18.16B
Investing Cash Flow-11.39B-10.64B-3.57B-6.55B-9.08B
Financing Cash Flow-6.82B-4.24B-15.72B-12.70B-9.24B

Roche Holding AG Technical Analysis

Technical Analysis Sentiment
Negative
Last Price260.00
Price Trends
50DMA
263.01
Negative
100DMA
272.53
Negative
200DMA
264.61
Negative
Market Momentum
MACD
-1.34
Positive
RSI
46.38
Neutral
STOCH
37.27
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CH:ROG, the sentiment is Negative. The current price of 260 is below the 20-day moving average (MA) of 262.78, below the 50-day MA of 263.01, and below the 200-day MA of 264.61, indicating a bearish trend. The MACD of -1.34 indicates Positive momentum. The RSI at 46.38 is Neutral, neither overbought nor oversold. The STOCH value of 37.27 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CH:ROG.

Roche Holding AG Peers Comparison

Overall Rating
UnderperformOutperform
Sector (63)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
81
Outperform
CHF186.74B17.19
3.57%6.34%-13.16%
77
Outperform
CHF16.78B43.40
0.90%3.82%57.08%
CHROG
74
Outperform
CHF209.85B25.0426.76%3.73%3.03%-27.86%
CHALC
73
Outperform
CHF34.91B34.795.23%0.32%3.90%6.76%
67
Neutral
CHF38.28B62.69
0.71%-2.13%2.50%
63
Neutral
CHF22.60B15.1310.81%2.13%47.85%-11.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CH:ROG
Roche Holding AG
260.00
24.10
10.22%
CH:NOVN
Novartis AG
98.12
4.26
4.54%
CH:LONN
Lonza Group Ltd
560.20
61.09
12.24%
CH:STMN
Straumann Holding AG
105.25
-11.57
-9.90%
CH:ALC
Alcon
69.86
-10.46
-13.02%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 17, 2025