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IBRN - ETF AI Analysis

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IBRN

iShares Neuroscience and Healthcare ETF (IBRN)

Rating:55Neutral
Price Target:
IBRN, the iShares Neuroscience and Healthcare ETF, has a mixed overall rating that reflects a balance between several strong, profitable biotech leaders and a number of higher-risk, unprofitable names. Strong holdings like Alkermes and Catalyst Pharma, which show solid financial performance, profitability, and positive outlooks, help support the fund’s quality, while weaker holdings such as Centessa Pharmaceuticals and Denali Therapeutics, which face significant financial and profitability challenges, weigh on the rating. The main risk factor is the fund’s concentration in early-stage or financially stressed biotech and neuroscience companies, which can lead to higher volatility and uncertainty for investors.
Positive Factors
Recent Performance Momentum
The ETF has shown solid recent gains over the last three months, suggesting improving momentum in its niche area.
Strong Contributors Among Top Holdings
Several of the largest positions, such as Alkermes and Praxis Precision Medicines, have delivered strong year-to-date performance, helping support the fund’s returns.
Targeted Exposure to Neuroscience and Healthcare
With the vast majority of assets in health care companies focused on neuroscience, the fund offers specialized exposure for investors who want to focus on this theme.
Negative Factors
High Sector Concentration
Over 90% of the portfolio is in the health care sector, which increases risk if this area faces regulatory or market pressure.
Mixed Performance Within Top Holdings
Several key holdings, including Xenon, Biogen, and PTC Therapeutics, have shown weak year-to-date performance, which can drag on overall returns.
Relatively High Expense Ratio for a Small Fund
The fund’s expense ratio is on the higher side for an ETF and assets under management are still small, meaning costs take a more noticeable bite out of investor returns.

IBRN vs. SPDR S&P 500 ETF (SPY)

IBRN Summary

The iShares Neuroscience and Healthcare ETF (IBRN) tracks the NYSE FactSet Global Neuro Biopharma and MedTech Index, focusing on companies working on brain-related drugs, treatments, and medical technology. It mainly holds U.S. health care stocks, including well-known names like Biogen, along with a range of smaller biotech firms developing new therapies. Someone might invest in IBRN to seek long-term growth from advances in neuroscience and cutting-edge medical research while getting diversification across many companies instead of picking a single stock. A key risk is that biotech and health care shares can be very volatile and may go up or down sharply.
How much will it cost me?The iShares Neuroscience and Healthcare ETF (IBRN) has an expense ratio of 0.47%, which means you’ll pay $4.70 per year for every $1,000 invested. This is slightly higher than average because it’s a sector-focused fund that requires more active management to target specific companies in the neuroscience and healthcare fields.
What would affect this ETF?The iShares Neuroscience and Healthcare ETF (IBRN) could benefit from growing global demand for advanced neurological treatments and breakthroughs in biotechnology, as well as increased funding for health care innovation. However, it may face challenges from regulatory hurdles in drug approvals, potential economic slowdowns impacting research budgets, and competition within the pharmaceutical and biotech sectors. Its global exposure and focus on cutting-edge companies provide opportunities but also expose it to risks tied to international market conditions.

IBRN Top 10 Holdings

IBRN is a tightly focused bet on neuroscience and biotech, with all its key players rooted in global health care rather than Big Tech. Praxis Precision Medicines and Biogen are doing much of the heavy lifting, with both stocks rising on the back of strong momentum and promising pipelines. Alkermes and Supernus look steady to rising, adding a bit of stability to this otherwise high-octane mix. On the flip side, PTC Therapeutics and Xenon are lagging, acting like a headwind that keeps the fund from fully capitalizing on its winners.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Praxis Precision Medicines5.39%$249.50K$8.61B753.38%
58
Neutral
Axsome Therapeutics4.68%$216.55K$8.41B38.48%
57
Neutral
Biogen4.38%$202.80K$27.63B24.90%
74
Outperform
Scholar Rock Holding4.33%$200.27K$5.08B25.83%
50
Neutral
Supernus Pharmaceuticals4.17%$193.18K$3.12B64.95%
55
Neutral
Alkermes4.17%$193.05K$4.74B-19.27%
80
Outperform
Xenon4.01%$185.42K$5.22B83.16%
48
Neutral
Catalyst Pharma3.82%$176.93K$3.03B19.93%
83
Outperform
Denali Therapeutics3.66%$169.22K$3.38B42.54%
45
Neutral
Centessa Pharmaceuticals3.55%$164.08K$3.51B65.13%
33
Underperform

IBRN Technical Analysis

Technical Analysis Sentiment
Positive
Last Price
Price Trends
50DMA
32.24
Positive
100DMA
31.20
Positive
200DMA
27.56
Positive
Market Momentum
MACD
-0.10
Negative
RSI
57.31
Neutral
STOCH
61.18
Neutral
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For IBRN, the sentiment is Positive. The current price of undefined is equal to the 20-day moving average (MA) of 32.00, equal to the 50-day MA of 32.24, and equal to the 200-day MA of 27.56, indicating a bullish trend. The MACD of -0.10 indicates Negative momentum. The RSI at 57.31 is Neutral, neither overbought nor oversold. The STOCH value of 61.18 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IBRN.

IBRN Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$4.62M0.47%
55
Neutral
$59.15M0.50%
60
Neutral
$54.08M0.59%
61
Neutral
$53.11M0.18%
69
Neutral
$51.92M0.68%
67
Neutral
$19.37M1.00%
48
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IBRN
iShares Neuroscience and Healthcare ETF
32.92
9.50
40.56%
FMED
Fidelity Disruptive Medicine ETF
OZEM
Roundhill GLP-1 & Weight Loss ETF
HRTS
Tema Cardiovascular and Metabolic ETF
HTEC
ROBO Global Healthcare Technology and Innovation ETF
PSIL
AdvisorShares Psychedelics ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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