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IBRN - ETF AI Analysis

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IBRN

iShares Neuroscience and Healthcare ETF (IBRN)

Rating:55Neutral
Price Target:
IBRN, the iShares Neuroscience and Healthcare ETF, has a middling overall rating that reflects a mix of strong, profitable biotech leaders and more speculative names with financial challenges. High-quality holdings like Alkermes, Argenx, and Neurocrine support the fund’s quality through solid financial performance, revenue growth, and positive earnings outlooks, while weaker positions such as Centessa and Scholar Rock, which face losses, negative cash flow, and bearish or mixed technical trends, drag on the rating. The main risk factor is the fund’s focus on early- and mid-stage biotech and neuroscience companies, which often have volatile stock prices and depend heavily on successful clinical trials and ongoing funding.
Positive Factors
Strong Recent Fund Performance
The ETF has shown solid gains so far this year and over the past month, indicating positive recent momentum.
Several Strong-Performing Top Holdings
A number of the largest positions, such as Xenon, Alkermes, Centessa, and Praxis, have delivered strong year-to-date results that support the fund’s overall performance.
Targeted Exposure to Neuroscience and Healthcare
The fund’s heavy focus on health care and neuroscience companies offers concentrated exposure to a specialized growth area within the medical sector.
Negative Factors
High Sector Concentration in Health Care
With the vast majority of assets in health care, the ETF is heavily exposed to risks specific to that sector.
Underperforming Key Holdings
Some top positions, including PTC Therapeutics, Argenx, and Neurocrine, have shown weak year-to-date performance, which can drag on the fund’s returns.
Limited Geographic Diversification
The portfolio is dominated by U.S. companies, offering little diversification across international markets.

IBRN vs. SPDR S&P 500 ETF (SPY)

IBRN Summary

The iShares Neuroscience and Healthcare ETF (IBRN) tracks the NYSE FactSet Global Neuro Biopharma and MedTech Index, focusing on health care companies working on brain and nervous system treatments. It mainly holds U.S. drug and biotech firms, including names like Neurocrine and Alkermes, that are developing new medicines and medical technologies. An investor might consider this ETF for targeted growth potential in cutting-edge health care and to spread risk across many neuroscience-focused companies instead of picking just one stock. However, it is concentrated in a single, specialized sector, so its price can be very volatile and may rise or fall more than the overall market.
How much will it cost me?The iShares Neuroscience and Healthcare ETF (IBRN) has an expense ratio of 0.47%, which means you’ll pay $4.70 per year for every $1,000 invested. This is slightly higher than average because it’s a sector-focused fund that requires more active management to target specific companies in the neuroscience and healthcare fields.
What would affect this ETF?The iShares Neuroscience and Healthcare ETF (IBRN) could benefit from growing global demand for advanced neurological treatments and breakthroughs in biotechnology, as well as increased funding for health care innovation. However, it may face challenges from regulatory hurdles in drug approvals, potential economic slowdowns impacting research budgets, and competition within the pharmaceutical and biotech sectors. Its global exposure and focus on cutting-edge companies provide opportunities but also expose it to risks tied to international market conditions.

IBRN Top 10 Holdings

IBRN is very much a one-theme story: it’s almost entirely health care, with a tight focus on neuroscience names from a global roster of biopharma and medtech players. Recent gains are being led by rising stars like Axsome Therapeutics and Neurocrine, which are helping pull the fund higher. Centessa has also been on a strong upswing, adding some extra fuel. On the flip side, Argenx and PTC Therapeutics have been more of a drag, reminding investors that this is a high-risk, high-reward corner of the market.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Axsome Therapeutics4.74%$254.95K$12.07B113.87%
57
Neutral
Alkermes4.59%$246.82K$7.03B35.09%
80
Outperform
Arrowhead Pharmaceuticals4.54%$244.08K$10.97B358.54%
57
Neutral
Xenon4.52%$243.04K$5.29B77.62%
48
Neutral
Neurocrine4.19%$225.60K$15.92B29.25%
80
Outperform
PTC Therapeutics4.10%$220.41K$6.13B51.14%
72
Outperform
Argenx Se3.88%$208.89K$51.51B43.02%
79
Outperform
Centessa Pharmaceuticals3.82%$205.42K$6.15B197.24%
33
Underperform
Praxis Precision Medicines3.79%$203.86K$9.76B741.69%
58
Neutral
Scholar Rock Holding3.73%$200.45K$5.91B59.24%
50
Neutral

IBRN Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price
Price Trends
50DMA
34.26
Negative
100DMA
33.19
Positive
200DMA
30.82
Positive
Market Momentum
MACD
0.15
Positive
RSI
41.65
Neutral
STOCH
60.64
Neutral
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For IBRN, the sentiment is Neutral. The current price of undefined is equal to the 20-day moving average (MA) of 35.17, equal to the 50-day MA of 34.26, and equal to the 200-day MA of 30.82, indicating a neutral trend. The MACD of 0.15 indicates Positive momentum. The RSI at 41.65 is Neutral, neither overbought nor oversold. The STOCH value of 60.64 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for IBRN.

IBRN Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$5.31M0.47%
55
Neutral
$56.00M0.68%
67
Neutral
$52.19M0.75%
66
Neutral
$49.76M0.59%
57
Neutral
$41.08M0.50%
57
Neutral
$36.08M1.00%
44
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IBRN
iShares Neuroscience and Healthcare ETF
33.81
11.23
49.73%
HTEC
ROBO Global Healthcare Technology and Innovation ETF
HRTS
Tema Cardiovascular and Metabolic ETF
OZEM
Roundhill GLP-1 & Weight Loss ETF
FMED
Fidelity Disruptive Medicine ETF
PSIL
AdvisorShares Psychedelics ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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