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Supernus Pharmaceuticals (SUPN)
NASDAQ:SUPN
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Supernus Pharmaceuticals (SUPN) AI Stock Analysis

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SUPN

Supernus Pharmaceuticals

(NASDAQ:SUPN)

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Neutral 55 (OpenAI - 4o)
Rating:55Neutral
Price Target:
$48.00
▲(5.08% Upside)
Supernus Pharmaceuticals demonstrates strong product growth and a stable balance sheet, but faces profitability and cash flow challenges. The technical analysis suggests potential for recovery, while valuation metrics are currently unattractive. The earnings call provided a positive outlook, but highlighted operational losses and supply issues.
Positive Factors
Revenue Growth
Consistent revenue growth reflects strong demand for Supernus's products, indicating successful market penetration and product adoption.
Product Performance
Strong performance of key products suggests robust demand and effective market strategies, supporting long-term revenue stability.
Financial Stability
A low debt-to-equity ratio enhances financial stability, providing flexibility for future investments and growth opportunities.
Negative Factors
Operating Losses
Significant operating losses can strain financial resources and impact profitability, necessitating cost management improvements.
Supply Constraints
Supply constraints hinder growth potential and customer satisfaction, requiring resolution to meet demand and sustain sales momentum.
Decreased Cash Reserves
Reduced cash reserves limit financial flexibility and may constrain the company's ability to invest in growth or manage unforeseen expenses.

Supernus Pharmaceuticals (SUPN) vs. SPDR S&P 500 ETF (SPY)

Supernus Pharmaceuticals Business Overview & Revenue Model

Company DescriptionSupernus Pharmaceuticals, Inc. is a specialty pharmaceutical company focused on the development and commercialization of products for the treatment of central nervous system (CNS) disorders. The company primarily targets conditions such as epilepsy and attention-deficit hyperactivity disorder (ADHD) with a portfolio of proprietary products that include marketed drugs like Oxtellar XR and Trokendi XR. Supernus operates in the biopharmaceutical sector, leveraging its expertise in drug formulation and development to enhance treatment options for patients.
How the Company Makes MoneySupernus Pharmaceuticals generates revenue through the sale of its pharmaceutical products, which are primarily focused on CNS disorders. The company earns money by marketing its approved medications to healthcare providers and pharmacies, with a significant portion of its revenue coming from prescriptions filled by patients. In addition to direct sales, Supernus may also engage in partnerships or licensing agreements with other pharmaceutical companies to expand its market reach or enhance its product offerings. These partnerships can provide additional revenue streams through upfront payments, milestone payments, and royalties on sales of partnered products. Furthermore, the company's commitment to research and development may lead to new product launches that can contribute to future earnings.

Supernus Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Neutral
The earnings call presented a mixed picture with strong growth in key products and an optimistic financial outlook overshadowed by significant operating losses and supply constraints for Onapgo. The company is addressing these challenges while maintaining a focus on future growth opportunities.
Q3-2025 Updates
Positive Updates
Strong Growth Products Performance
Qelbree, GOCOVRI, Zurzuvae, and Onapgo accounted for approximately 78% of total revenues. Qelbree achieved 23% growth in prescriptions and 31% growth in net sales compared to the same period last year.
Onapgo Sales Surge
Onapgo generated net sales of $6.8 million in the third quarter, up from $1.6 million in the second quarter.
Zurzuvae Collaboration Revenue
Collaboration revenue from Zurzuvae was $20.2 million in the third quarter of 2025, with U.S. sales increasing approximately 150% compared to the same period in 2024.
Positive Financial Outlook
Updated full year 2025 financial guidance, increasing expected total revenue to range from $685 million to $705 million, up from the previous range of $670 million to $700 million.
Negative Updates
Operating Losses Due to Acquisition Costs
Operating loss on a GAAP basis for the third quarter of 2025 was $60.2 million, primarily due to higher SG&A expenses including $70 million of acquisition-related costs from the Sage acquisition.
Supply Constraints for Onapgo
Stronger-than-expected demand for Onapgo led to supplier constraints, impacting the company's ability to meet demand and pausing delivery to new patients.
Decreased Cash Reserves
As of September 30, 2025, the company had approximately $281 million in cash, cash equivalents, and marketable securities, compared to $454 million as of December 31, 2024, due to the funding of the Sage acquisition.
Company Guidance
In the third quarter of 2025, Supernus Pharmaceuticals reported robust performance driven by its four growth products—Qelbree, GOCOVRI, Zurzuvae, and Onapgo—accounting for approximately 78% of total revenues. Onapgo net sales surged from $1.6 million in Q2 to $6.8 million in Q3, despite supplier constraints limiting its ability to meet high demand. Collaboration revenue from Zurzuvae reached $20.2 million, showcasing a 150% increase in U.S. sales compared to Q3 2024. Qelbree prescriptions grew by 23%, with net sales up 31% year-over-year, bolstered by a strong back-to-school season. GOCOVRI's net sales rose by 15% from the previous year, reflecting growth in prescriptions and prescriber numbers. Total revenue for Q3 2025 was $192.1 million, marking an increase from $175.7 million in Q3 2024. The company updated its 2025 guidance, expecting total revenue between $685 million and $705 million, and non-GAAP operating earnings ranging from $125 million to $145 million.

Supernus Pharmaceuticals Financial Statement Overview

Summary
Supernus Pharmaceuticals shows strong revenue growth and a solid gross profit margin. However, it faces challenges with profitability and cash flow management. The balance sheet is stable with low leverage, but negative return on equity and cash flow issues suggest areas for improvement.
Income Statement
45
Neutral
Supernus Pharmaceuticals shows a strong gross profit margin of over 90% in the TTM, indicating efficient production and sales processes. However, the company is currently experiencing negative net profit and EBIT margins, reflecting operational challenges and potential inefficiencies. The revenue growth rate is exceptionally high, suggesting a significant increase in sales, but the negative profitability metrics overshadow this growth.
Balance Sheet
60
Neutral
The company's debt-to-equity ratio is low, indicating a conservative approach to leveraging, which is a positive sign of financial stability. However, the return on equity is negative in the TTM, highlighting concerns about the company's ability to generate returns for shareholders. The equity ratio is healthy, suggesting a strong capital base relative to assets.
Cash Flow
50
Neutral
Operating cash flow is positive, but the operating cash flow to net income ratio is low, indicating potential issues in converting income into cash. The free cash flow growth rate is negative, suggesting challenges in maintaining cash reserves. However, the free cash flow to net income ratio is nearly 1, indicating efficient cash management relative to net income.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue681.54M661.82M607.52M667.24M579.77M520.40M
Gross Profit574.52M583.91M523.74M580.02M504.71M467.94M
EBITDA59.92M178.28M90.04M153.36M129.19M210.54M
Net Income-19.12M73.86M1.32M60.71M53.42M126.95M
Balance Sheet
Total Assets1.42B1.37B1.28B1.70B1.69B1.50B
Cash, Cash Equivalents and Short-Term Investments281.16M453.61M254.87M461.33M339.68M422.53M
Total Debt31.42M34.27M41.53M444.76M427.03M414.32M
Total Liabilities370.09M332.34M356.16M816.30M873.30M759.24M
Stockholders Equity1.05B1.04B921.52M886.20M815.85M744.86M
Cash Flow
Free Cash Flow132.54M171.23M110.53M116.41M125.08M134.95M
Operating Cash Flow133.54M171.95M111.08M116.83M127.13M138.40M
Investing Cash Flow-5.93M-189.87M268.73M-216.66M-81.91M-34.70M
Financing Cash Flow-14.57M12.19M-397.88M-10.48M-130.42M3.56M

Supernus Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price45.68
Price Trends
50DMA
48.39
Negative
100DMA
44.95
Positive
200DMA
38.55
Positive
Market Momentum
MACD
-1.01
Negative
RSI
45.87
Neutral
STOCH
37.46
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SUPN, the sentiment is Positive. The current price of 45.68 is above the 20-day moving average (MA) of 45.24, below the 50-day MA of 48.39, and above the 200-day MA of 38.55, indicating a neutral trend. The MACD of -1.01 indicates Negative momentum. The RSI at 45.87 is Neutral, neither overbought nor oversold. The STOCH value of 37.46 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SUPN.

Supernus Pharmaceuticals Risk Analysis

Supernus Pharmaceuticals disclosed 58 risk factors in its most recent earnings report. Supernus Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Supernus Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$1.23B11.8714.84%-0.03%-27.66%
64
Neutral
$1.84B50.157.83%48.87%
60
Neutral
$2.09B-0.32%79.88%99.60%
55
Neutral
$2.62B-1.86%4.54%-130.59%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.85B-35.68-0.65%8.63%-2.55%66.00%
42
Neutral
$1.66B23.8455.38%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SUPN
Supernus Pharmaceuticals
45.68
9.00
24.54%
AVDL
Avadel Pharmaceuticals
21.34
11.19
110.25%
PRGO
Perrigo Company
13.44
-13.00
-49.17%
ANIP
ANI Pharmaceuticals
81.77
23.74
40.91%
AMPH
Amphastar Pharmaceuticals
26.77
-17.06
-38.92%
ALVO
Alvotech
5.47
-5.81
-51.51%

Supernus Pharmaceuticals Corporate Events

Product-Related AnnouncementsM&A TransactionsBusiness Operations and StrategyFinancial Disclosures
Supernus Faces Supply Constraints Amid High ONAPGO Demand
Neutral
Nov 4, 2025

On November 4, 2025, Supernus Pharmaceuticals announced that due to stronger than expected demand for ONAPGO, supplier constraints are impacting the company’s ability to fully meet this demand. As a result, the company is prioritizing care for patients currently on ONAPGO by pausing delivery to new patients. The company is working to build adequate inventory and resume new patient initiations as soon as possible. Additionally, Supernus reported a 52% increase in combined revenues of its four growth products in the third quarter of 2025, driven by an increase in net sales of Qelbree and GOCOVRI, and the addition of sales from ZURZUVAE and ONAPGO. The company also completed the acquisition of Sage Therapeutics, Inc. on July 31, 2025, and increased its full-year 2025 revenue guidance.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 07, 2025