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Supernus Pharmaceuticals (SUPN)
NASDAQ:SUPN
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Supernus Pharmaceuticals (SUPN) AI Stock Analysis

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SUPN

Supernus Pharmaceuticals

(NASDAQ:SUPN)

Rating:76Outperform
Price Target:
$48.00
▲(12.44% Upside)
Supernus Pharmaceuticals demonstrates strong financial health and technical momentum, supported by strategic acquisitions. However, high valuation and patent challenges pose risks. The company's robust cash flow and operational efficiency are key strengths, but attention to revenue growth and cost management is crucial for sustaining long-term performance.
Positive Factors
Earnings
Qelbree achieved $77.6MM in Q2 sales, exceeding consensus and showing strong growth.
Market Growth
Analyst expects Qelbree to steadily grow, focusing on the adult launch with increasing adoption in the segment.
Patent Extension
Qelbree's '338 patent has been extended by 2 years to 2035, which buys time for management to introduce more pipeline assets.
Negative Factors
Clinical Trial Results
Disappointing Phase 2b data from SPN-820 in treatment-resistant patients led to a downgrade of the stock rating.
Stock Rating
Downgrading SUPN to Neutral following disappointing Phase 2b data from SPN-820.

Supernus Pharmaceuticals (SUPN) vs. SPDR S&P 500 ETF (SPY)

Supernus Pharmaceuticals Business Overview & Revenue Model

Company DescriptionSupernus Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing innovative products for the treatment of central nervous system (CNS) diseases. The company primarily operates in the pharmaceutical sector, specializing in therapies for epilepsy, depression, and attention deficit hyperactivity disorder (ADHD). Supernus's core products include several FDA-approved medications such as Oxtellar XR and Trokendi XR, which are designed to address the needs of patients suffering from these conditions.
How the Company Makes MoneySupernus Pharmaceuticals generates revenue primarily through the sale of its prescription medications. The company's key revenue streams include sales of its core products, particularly Oxtellar XR and Trokendi XR, which are marketed to healthcare providers and patients. Additionally, Supernus engages in strategic partnerships and collaborations with other pharmaceutical companies, which can provide upfront payments, milestone payments, and royalties on sales of co-developed products. The company's focus on expanding its product portfolio through research and development initiatives, along with potential new product launches, also contributes to its revenue generation. Supernus's earnings are further supported by its ability to navigate the complex regulatory environment for drug approvals, ensuring that its products reach the market effectively.

Supernus Pharmaceuticals Earnings Call Summary

Earnings Call Date:Aug 05, 2025
(Q2-2025)
|
% Change Since: 13.75%|
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted strong growth in core products and a successful acquisition, setting the stage for future growth. However, this was offset by decreased operating earnings and increased expenses. Overall, the sentiment is cautiously optimistic.
Q2-2025 Updates
Positive Updates
Strong Launch of ONAPGO
ONAPGO, the first and only subcutaneous apomorphine infusion device for Parkinson's disease, was launched in April and exceeded expectations with more than 750 patient enrollment forms submitted by over 300 prescribers.
Acquisition of Sage Therapeutics
Supernus completed the acquisition of Sage Therapeutics on July 31, which is expected to accelerate mid- to long-term revenue growth and cash flow.
Growth of Core Products
Qelbree and GOCOVRI showed strong performance, with Qelbree prescriptions growing by 23% and net sales up by 31%. GOCOVRI saw a 14% increase in prescriptions and a 16% rise in net sales year-over-year.
Introduction of ZURZUVAE
ZURZUVAE, acquired from Sage Therapeutics, reported net revenues of $23.2 million in Q2 2025, a 68% increase from the previous quarter.
Financial Position and Guidance
Supernus ended Q2 with $523 million in cash and marketable securities, and increased its 2025 revenue guidance to $670 million to $700 million.
Negative Updates
Decrease in Operating Earnings
Operating earnings on a GAAP basis for Q2 2025 were $12 million, down from $23 million in the same quarter last year, primarily due to higher sales and marketing expenses related to the ONAPGO launch.
Flat Total Revenue
Total revenue for Q2 2025 was $165 million, slightly down from $168 million in the same quarter last year.
Increased Expenses
Combined R&D and SG&A expenses for the first half of 2025 were $233 million, up from $224 million in the same period last year, driven by the ONAPGO launch and Sage acquisition.
Company Guidance
In the second quarter of 2025, Supernus Pharmaceuticals reported significant developments and strong financial performance. The company launched ONAPGO, a subcutaneous apomorphine infusion device for advanced Parkinson's disease, and completed the acquisition of Sage Therapeutics. Their growth drivers, Qelbree, GOCOVRI, and ONAPGO, collectively accounted for 73% of total net sales. Qelbree prescriptions grew by 23% year-over-year, with net sales increasing by 31%. GOCOVRI saw a 14% rise in prescriptions and a 16% increase in net sales, while ONAPGO had over 750 patient enrollment forms submitted by more than 300 prescribers. The acquisition of ZURZUVAE, a product from Sage, added to their growth trajectory, with its net revenues increasing by 68% quarter-over-quarter to $23.2 million. Financially, Supernus reported total revenues of $165 million, with net product sales of $158 million. Despite a decrease in GAAP operating earnings to $12 million from $23 million the previous year, the company's cash position strengthened to approximately $523 million, enabling continued strategic growth initiatives. Updated guidance for full-year 2025 forecasts total revenues between $670 million and $700 million, with non-GAAP operating earnings expected to range from $105 million to $135 million.

Supernus Pharmaceuticals Financial Statement Overview

Summary
Supernus Pharmaceuticals demonstrates a strong financial position with robust margins and a solid equity base. The company maintains low leverage, reducing financial risk while ensuring ample liquidity. Despite moderate revenue growth, stable cash flows and efficient cost management underscore its operational resilience. Opportunities exist to enhance shareholder returns through improved net income generation.
Income Statement
76
Positive
Supernus Pharmaceuticals demonstrated a solid gross profit margin of 79.5% in the TTM, indicating strong cost management. The net profit margin of 9.3% suggests reasonable profitability, despite a slight decline from the previous year. Revenue growth is relatively modest, reflecting stable but limited expansion opportunities. EBITDA margin is healthy at 25.0%, supporting operational efficiency.
Balance Sheet
82
Very Positive
The company exhibits a robust equity position with an equity ratio of 76.5% in the TTM, highlighting financial stability. The debt-to-equity ratio is low at 0.03, indicating minimal leverage and reduced financial risk. Return on equity is moderate at 6.0%, suggesting room for improvement in generating returns for shareholders.
Cash Flow
79
Positive
Operating cash flow remains strong with an operating cash flow to net income ratio of 2.65, indicating efficient cash generation relative to income. Free cash flow growth has been stable, supporting potential reinvestment or shareholder returns. However, the free cash flow to net income ratio of 2.64 suggests a balanced but not overly aggressive cash deployment strategy.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue665.13M661.82M607.52M667.24M579.77M520.40M
Gross Profit547.45M583.91M523.74M580.02M504.71M467.94M
EBITDA166.03M178.28M90.04M153.44M129.19M212.40M
Net Income64.50M73.86M1.32M60.71M53.42M126.95M
Balance Sheet
Total Assets1.38B1.37B1.28B1.70B1.69B1.50B
Cash, Cash Equivalents and Short-Term Investments522.60M453.61M254.87M461.33M339.68M422.53M
Total Debt31.77M34.27M41.53M437.97M420.55M390.33M
Total Liabilities318.50M332.34M356.16M816.30M873.30M759.24M
Stockholders Equity1.06B1.04B921.52M886.20M815.85M744.86M
Cash Flow
Free Cash Flow185.87M171.23M110.53M116.41M125.08M134.95M
Operating Cash Flow187.06M171.95M111.08M116.83M127.13M138.40M
Investing Cash Flow-82.94M-189.87M268.73M-216.66M-81.91M-34.70M
Financing Cash Flow-11.50M12.19M-397.88M-10.48M-130.42M3.56M

Supernus Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price42.69
Price Trends
50DMA
34.39
Positive
100DMA
33.20
Positive
200DMA
34.55
Positive
Market Momentum
MACD
2.55
Negative
RSI
76.01
Negative
STOCH
86.13
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SUPN, the sentiment is Positive. The current price of 42.69 is above the 20-day moving average (MA) of 37.27, above the 50-day MA of 34.39, and above the 200-day MA of 34.55, indicating a bullish trend. The MACD of 2.55 indicates Negative momentum. The RSI at 76.01 is Negative, neither overbought nor oversold. The STOCH value of 86.13 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for SUPN.

Supernus Pharmaceuticals Risk Analysis

Supernus Pharmaceuticals disclosed 56 risk factors in its most recent earnings report. Supernus Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Supernus Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
76
Outperform
$2.36B36.866.38%5.55%1145.24%
68
Neutral
$1.95B-2.82%38.68%-160.14%
62
Neutral
$1.40B11.3118.32%1.37%-18.10%
58
Neutral
$2.95B1,476.56106.97%9.81%
54
Neutral
$1.25B64.45-9.28%26.66%-419.55%
51
Neutral
$7.46B-0.16-46.00%2.25%22.76%-2.28%
47
Neutral
$1.35B-16.34%0.45%-125.61%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SUPN
Supernus Pharmaceuticals
42.69
8.14
23.56%
DVAX
Dynavax
10.79
-0.41
-3.66%
ANIP
ANI Pharmaceuticals
87.47
27.45
45.73%
AMPH
Amphastar Pharmaceuticals
29.83
-15.13
-33.65%
EVO
Evotec AG
3.76
0.50
15.34%
AMRX
Amneal Pharmaceuticals
9.45
1.41
17.54%

Supernus Pharmaceuticals Corporate Events

M&A Transactions
Supernus Pharmaceuticals Completes Acquisition of Sage Therapeutics
Positive
Jul 31, 2025

On July 31, 2025, Supernus Pharmaceuticals completed its acquisition of Sage Therapeutics, enhancing its presence in neuropsychiatric conditions with the addition of ZURZUVAE, an FDA-approved treatment for postpartum depression. The acquisition, valued at approximately $561 million, is expected to diversify Supernus’ revenue base and accelerate growth, with projected cost synergies of up to $200 million annually. The merger was completed without a stockholder vote, and Sage now operates as a wholly owned subsidiary of Supernus.

The most recent analyst rating on (SUPN) stock is a Buy with a $41.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Supernus Pharmaceuticals Holds Annual Stockholders Meeting
Neutral
Jun 17, 2025

On June 16, 2025, Supernus Pharmaceuticals held its annual stockholders meeting, where key decisions were made regarding the election of directors, executive compensation, and the appointment of KPMG LLP as the independent public accounting firm for 2025. These decisions are expected to influence the company’s governance and financial oversight, impacting its strategic direction and stakeholder confidence.

The most recent analyst rating on (SUPN) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

M&A Transactions
Supernus Pharmaceuticals to Acquire Sage Therapeutics
Positive
Jun 16, 2025

On June 13, 2025, Supernus Pharmaceuticals announced a definitive agreement to acquire Sage Therapeutics through a tender offer valued at approximately $795 million. This acquisition is expected to enhance Supernus’ neuropsychiatry product portfolio with the addition of ZURZUVAE, an FDA-approved treatment for postpartum depression, and is anticipated to be significantly accretive by 2026, with potential cost synergies of up to $200 million annually.

The most recent analyst rating on (SUPN) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

Legal ProceedingsBusiness Operations and Strategy
Supernus Pharmaceuticals Faces Patent Challenges for Qelbree
Negative
May 28, 2025

On May 22 and 23, 2025, Supernus Pharmaceuticals received Paragraph IV Notice Letters indicating that third parties filed Abbreviated New Drug Applications (ANDAs) for viloxazine hydrochloride capsules, challenging the patents of their product Qelbree. Supernus plans to enforce its intellectual property rights, which are protected by six U.S. patents expiring between 2029 and 2035, potentially impacting its market position and stakeholder interests.

The most recent analyst rating on (SUPN) stock is a Buy with a $40.00 price target. To see the full list of analyst forecasts on Supernus Pharmaceuticals stock, see the SUPN Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 14, 2025