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Amphastar Pharmaceuticals (AMPH)
NASDAQ:AMPH

Amphastar Pharmaceuticals (AMPH) AI Stock Analysis

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Amphastar Pharmaceuticals

(NASDAQ:AMPH)

Rating:79Outperform
Price Target:
$30.00
▲(15.47%Upside)
Amphastar Pharmaceuticals' strong financial performance and attractive valuation are key strengths, offset by mixed signals from technical analysis and earnings call challenges. While the company shows potential for growth, ongoing competitive pressures and margin challenges must be addressed for sustained success.
Positive Factors
Growth Products
Baqsimi and Primatene Mist are delivering better than expected growth, with Primatene showing especially strong performance.
Pipeline Optimism
Management expressed optimism for potential approvals of AMP-002 and AMP-007, citing recent positive interactions with the FDA.
Stock Valuation
Despite challenges, AMPH shares remain very inexpensive at these levels, suggesting potential value to investors.
Negative Factors
Generic Portfolio Erosion
Both glucagon and epinephrine are eroding faster than the Street was expecting, which analysts predict will lead to significant challenges.
Pipeline Setbacks
The company has faced continued setbacks on the pipeline front, including the two most recent CRLs on AMP-007 and AMP-018, which were key to offsetting erosion for the generic portfolio.
Revenue and Margin Pressure
Amphastar is facing several headwinds in 2025/2026, with anticipated significant revenue decline in Glucagon and a cautious outlook on epinephrine.

Amphastar Pharmaceuticals (AMPH) vs. SPDR S&P 500 ETF (SPY)

Amphastar Pharmaceuticals Business Overview & Revenue Model

Company DescriptionAmphastar Pharmaceuticals, Inc., a bio-pharmaceutical company, develops, manufactures, markets, and sells generic and proprietary injectable, inhalation, and intranasal products in the United States, China, and France. The company operates through two segments, Finished Pharmaceutical Products and API. It offers Primatene Mist, an over-the-counter epinephrine inhalation product for the temporary relief of mild symptoms of intermittent asthma; Enoxaparin, a low molecular weight heparin to prevent and treat deep vein thrombosis; Naloxone for opioid overdose; Glucagon for injection emergency kit; and Cortrosyn, a lyophilized powder for use as a diagnostic agent in the screening of patients with adrenocortical insufficiency. The company also provides Amphadase, a bovine-sourced hyaluronidase injection to absorb and disperse other injected drugs; Epinephrine injection for the emergency treatment of allergic reactions; lidocaine jelly, an anesthetic product for urological procedures; lidocaine topical solution for various procedures; phytonadione injection, a vitamin K1 injection for newborn babies; emergency syringe products for emergency use in hospital settings; morphine injection for use with patient controlled analgesia pumps; and lorazepam injection for surgery and medical procedures. In addition, it offers neostigmine methylsulfate injection to treat myasthenia gravis and to reverse the effects of muscle relaxants; and Isoproterenol hydrochloride injection for mild or transient episodes of heart block. Further, the company distributes recombinant human insulin active pharmaceutical ingredients (API) and porcine insulin API. It serves hospitals, care facilities, alternate care sites, clinics, and doctors' offices. The company was founded in 1996 and is headquartered in Rancho Cucamonga, California.
How the Company Makes MoneyAmphastar Pharmaceuticals makes money primarily through the sale of its pharmaceutical products. Its revenue model is based on the manufacturing and distribution of generic and proprietary injectable and inhalation products, along with APIs. The company generates significant income from its generic product segment, which includes critical injectable medications used in hospitals and clinics. Amphastar also engages in strategic partnerships and alliances with other pharmaceutical companies to enhance its product offerings and expand its market reach. Additionally, the company invests in research and development to innovate and bring new products to market, which can drive future revenue growth. Sales to wholesalers, distributors, retail pharmacy chains, and group purchasing organizations constitute key revenue streams for the company.

Amphastar Pharmaceuticals Earnings Call Summary

Earnings Call Date:May 07, 2025
(Q1-2025)
|
% Change Since: 6.34%|
Next Earnings Date:Aug 11, 2025
Earnings Call Sentiment Neutral
The earnings call revealed a mixed performance with notable achievements in product sales growth and strategic partnerships, but also significant challenges in revenue decline and increased competition affecting key products like Glucagon and Epinephrine. Operational efficiency measures and pipeline progress provide optimism for the future, but current financial pressures and competition present ongoing challenges.
Q1-2025 Updates
Positive Updates
Drug Shortage Assistance Award
Amphastar received the Drug Shortage Assistance Award from the USFDA for its efforts in preventing critical drug shortages.
BAQSIMI Sales Growth
BAQSIMI sales grew 177% to $38.4 million compared to $13.8 million in the prior year period, reflecting Amphastar's full control over distribution.
Primatene MIST Sales Increase
Sales of Primatene MIST increased by 20% to $29 million, attributed to increased unit volumes and demand.
Pipeline Progress
The FDA accepted a Biologics License Application for AMP-004, with a BsUFA goal date in Q1 2026, marking a milestone in expanding biosimilar insulin offerings.
Operational Efficiency Measures
Amphastar is implementing cost-efficient strategies to combat margin pressures and enhance operational effectiveness.
Negative Updates
Net Revenue Decline
Net revenues declined by 1% to $170.5 million compared to the same period last year due to increased competition in key product areas.
Glucagon and Epinephrine Sales Decline
Glucagon injection sales declined 27% and Epinephrine sales decreased 29% due to increased competition.
Gross Margin Reduction
Gross margins declined to 50% from 52.4% in the previous year, primarily due to the transition of BAQSIMI distribution from Lilly to Amphastar and pricing declines for Epinephrine.
Increased Operating Expenses
Selling, distribution, and marketing expenses increased 27%, and research and development expenditures rose 18%.
Net Income Decrease
Net income decreased to $25.3 million or $0.51 per share from $43.2 million or $0.81 per share in the first quarter of 2024.
Company Guidance
During Amphastar Pharmaceuticals' first quarter earnings call for fiscal year 2025, the management provided guidance on several key metrics and strategic initiatives. The company reported net revenues of $170.5 million, marking a 1% decrease from the previous year. BAQSIMI achieved sales of $38.3 million in the first quarter, nearly matching the combined sales of this product by Lilly and Amphastar from the prior year. Primatene MIST sales rose 20% to $29 million, driven by increased unit volumes and expanded physician outreach. Despite competitive pressures leading to a 27% decline in Glucagon injection sales to $20.8 million and a 29% decrease in Epinephrine sales to $18.6 million, Amphastar remains optimistic about its long-term growth prospects. The company continues to focus on expanding its branded product portfolio and anticipates that BAQSIMI and Primatene MIST will drive revenue growth throughout 2025. Furthermore, Amphastar is actively pursuing several pipeline opportunities, with an emphasis on capturing near-term growth through strategic FDA filings and responses. The company is also preparing for potential impacts from tariff policies but believes its U.S.-based manufacturing operations position it favorably.

Amphastar Pharmaceuticals Financial Statement Overview

Summary
Amphastar Pharmaceuticals shows strong financial health with consistent revenue growth and solid profitability margins. While there is a slight decline in net profit margin, the company's operational efficiency and effective cash flow management provide a strong foundation. The balanced leverage and robust ROE further underline its financial stability. Overall, Amphastar is well-positioned for sustainable growth, with some areas for improvement in margin expansion and liability management.
Income Statement
85
Very Positive
Amphastar Pharmaceuticals demonstrates strong financial performance with consistent revenue growth, evidenced by a TTM revenue of $728.26M, a 3.24% growth from the previous year. The gross profit margin remains solid at 50.24%, indicating effective cost management. However, the net profit margin has slightly decreased to 19.45% in the TTM period from 22.37% in 2024, suggesting some pressure on profitability. The EBIT margin is stable at 26.74%, while the EBITDA margin is healthy at 33.03%, reflecting strong operational efficiency.
Balance Sheet
78
Positive
The company's balance sheet shows a moderate debt-to-equity ratio of 0.87, indicating a balanced approach to leveraging. Return on Equity (ROE) is robust at 18.85%, showcasing effective use of equity capital. The equity ratio stands at 46.19%, suggesting a solid capital structure with room for improvement in reducing liabilities further.
Cash Flow
82
Very Positive
Amphastar has demonstrated strong cash flow generation with a free cash flow growth of -12.84% in the latest TTM period, which is a decline but still positive in absolute terms at $150.23M. The operating cash flow to net income ratio is impressive at 1.36, indicating good cash generation from operations. The free cash flow to net income ratio is 1.06, reflecting efficient capital expenditure management.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
728.26M712.81M644.39M498.99M437.77M349.85M
Gross Profit
365.89M373.86M351.12M248.86M199.74M143.34M
EBIT
194.70M205.42M196.99M78.76M43.13M-14.23M
EBITDA
255.58M277.31M240.29M107.50M111.78M30.19M
Net Income Common Stockholders
141.63M159.52M137.54M91.39M62.12M1.10M
Balance SheetCash, Cash Equivalents and Short-Term Investments
236.88M221.65M256.81M175.76M136.67M105.62M
Total Assets
1.63B1.58B1.51B741.99M671.53M631.24M
Total Debt
652.53M650.55M623.64M102.58M104.66M67.27M
Net Debt
469.75M498.94M479.35M-53.52M-21.69M-25.37M
Total Liabilities
874.99M845.17M873.49M213.33M226.01M182.51M
Stockholders Equity
751.28M732.30M639.42M528.66M445.52M402.31M
Cash FlowFree Cash Flow
150.23M172.34M145.34M65.15M70.54M23.41M
Operating Cash Flow
193.17M213.39M183.50M89.18M97.99M57.27M
Investing Cash Flow
-129.69M-124.93M-649.12M-32.78M-28.67M-36.41M
Financing Cash Flow
-81.88M-80.95M454.09M-26.44M-37.02M-2.25M

Amphastar Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price25.98
Price Trends
50DMA
24.76
Positive
100DMA
27.65
Negative
200DMA
36.28
Negative
Market Momentum
MACD
0.37
Negative
RSI
53.63
Neutral
STOCH
41.28
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AMPH, the sentiment is Negative. The current price of 25.98 is above the 20-day moving average (MA) of 25.57, above the 50-day MA of 24.76, and below the 200-day MA of 36.28, indicating a neutral trend. The MACD of 0.37 indicates Negative momentum. The RSI at 53.63 is Neutral, neither overbought nor oversold. The STOCH value of 41.28 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AMPH.

Amphastar Pharmaceuticals Risk Analysis

Amphastar Pharmaceuticals disclosed 85 risk factors in its most recent earnings report. Amphastar Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Amphastar Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$1.22B9.3719.90%8.05%-8.46%
62
Neutral
$1.35B-23.20%24.49%5.14%
59
Neutral
$1.13B-12.27%3.08%-247.82%
59
Neutral
$1.56B-43.33%22.29%-32.89%
54
Neutral
$5.34B3.27-45.10%3.30%16.80%0.02%
WVWVE
53
Neutral
$1.06B-105.50%-7.06%-57.17%
DYDYN
43
Neutral
$1.64B-64.01%14.93%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AMPH
Amphastar Pharmaceuticals
25.98
-14.07
-35.13%
CLDX
Celldex
20.06
-14.60
-42.12%
PCRX
Pacira Pharmaceuticals
24.34
-3.85
-13.66%
WVE
Wave Life Sciences
6.85
1.14
19.96%
SDGR
Schrodinger
20.88
1.56
8.07%
DYN
Dyne Therapeutics
10.86
-22.29
-67.24%

Amphastar Pharmaceuticals Corporate Events

Executive/Board ChangesShareholder MeetingsBusiness Operations and Strategy
Amphastar Pharmaceuticals Stockholders Approve Key Amendments
Neutral
Jun 4, 2025

At the 2025 Annual Meeting of Stockholders held on June 2, 2025, Amphastar Pharmaceuticals‘ stockholders approved several key amendments to the company’s Charter and Bylaws. These included changes to reflect Delaware law provisions regarding officer exculpation and the removal of the forum selection provision. Additionally, the election of three Class III directors, the ratification of Ernst & Young LLP as the independent accounting firm, and the approval of executive compensation were confirmed. These decisions are expected to impact the company’s governance structure and operational flexibility, potentially influencing its strategic direction and stakeholder relations.

The most recent analyst rating on (AMPH) stock is a Hold with a $31.00 price target. To see the full list of analyst forecasts on Amphastar Pharmaceuticals stock, see the AMPH Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.