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Pacira Pharmaceuticals (PCRX)
NASDAQ:PCRX

Pacira Pharmaceuticals (PCRX) AI Stock Analysis

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PCRX

Pacira Pharmaceuticals

(NASDAQ:PCRX)

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Neutral 64 (OpenAI - 5.2)
Rating:64Neutral
Price Target:
$21.00
▲(2.24% Upside)
The score is driven primarily by solid financial health and cash flow strength with minimal leverage, supported by a generally positive earnings-call outlook. This is tempered by weak technicals (price below key moving averages with negative MACD) and a relatively high P/E with no dividend support.
Positive Factors
Balance sheet strength
Extremely low leverage (debt/equity ~0.013) gives Pacira durable financial flexibility to fund R&D, advance pipeline assets, pursue partnerships or weather cyclical downturns without relying on dilutive or expensive external financing. This underpins long-term strategic optionality.
Consistent cash generation
Strong cash conversion (OCF/net income 1.32, FCF growth 6.1% TTM, FCF/net income 0.88) provides sustainable internal funding for product development, commercial investment, and $50M share repurchases, reducing reliance on external capital and supporting long-term value creation.
EXPAREL traction and improving margins
Renewed EXPAREL demand (volumes up ~9%) alongside higher non-GAAP gross margins (82% vs 78% prior year) indicates durable product adoption and manufacturing efficiencies. Patent listings and in-licensing (AMT-143) strengthen the product franchise and future organic growth prospects.
Negative Factors
Low net profitability
A net margin near 4.1% limits retained earnings and weakens the company’s ability to self-fund aggressive growth or absorb sustained pricing pressure. Even with solid gross margins, limited bottom-line profitability constrains long-term free cash flow expansion and shareholder returns.
Modest revenue growth trend
TTM revenue growth around 1.5% signals slow top-line momentum despite recent quarterly improvement. Sustained low organic growth raises execution risk for the company’s multi-year ‘5x30’ target, making attainment contingent on successful pipeline launches or market-share gains rather than base business expansion.
Pricing and market-access pressure
Contract-driven GPO discounting is a structural headwind that can erode realized prices and margins over time. With material reliance on EXPAREL sales, sustained pricing pressure and reduced net selling prices amplify revenue volatility and elevate the importance of scale or new differentiated products to protect profitability.

Pacira Pharmaceuticals (PCRX) vs. SPDR S&P 500 ETF (SPY)

Pacira Pharmaceuticals Business Overview & Revenue Model

Company DescriptionPacira BioSciences, Inc. provides non-opioid pain management and regenerative health solutions for healthcare practitioners and their patients in the United States. The company offers EXPAREL, a bupivacaine liposome injectable suspension; ZILRETTA, a triamcinolone acetonide extended-release injectable suspension; and iovera system, a non-opioid handheld cryoanalgesia device used to produce controlled doses of cold temperature only to targeted nerves. It also develops proprietary multivesicular liposome, a drug delivery technology that encapsulates drugs without altering their molecular structure. The company was formerly known as Pacira Pharmaceuticals, Inc. and changed its name to Pacira BioSciences, Inc. in April 2019. Pacira BioSciences, Inc. was incorporated in 2006 and is headquartered in Tampa, Florida.
How the Company Makes MoneyPacira Pharmaceuticals generates revenue primarily through the sales of its flagship product, EXPAREL, which is marketed to hospitals, surgical centers, and healthcare providers. The company also earns revenue from collaborations and partnerships with other pharmaceutical firms, which may include licensing agreements or co-development arrangements for its pipeline products. Additionally, Pacira may benefit from government reimbursements and healthcare insurance payments for its products, which are crucial for driving sales and expanding market access. The company has strategically focused on building relationships with healthcare professionals and institutions to promote the adoption of non-opioid pain management solutions, contributing to its overall revenue growth.

Pacira Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth, improved manufacturing efficiencies, and significant pipeline expansion. However, some challenges were noted with Zilretta's slower-than-expected sales growth and discount impacts from new GPO agreements affecting pricing. Elective procedure market growth was also described as sluggish.
Q3-2025 Updates
Positive Updates
Revenue Growth
Year-over-year revenues increased by 6%, driven by strong performance from EXPAREL and iovera. EXPAREL demand increased with year-over-year volumes up approximately 9%, marking the highest quarterly growth in over 3 years.
Manufacturing and Gross Margin
Improved manufacturing efficiencies and gross margins supported an increase in full-year guidance. Non-GAAP gross margins improved to 82% in the third quarter from 78% last year.
Pipeline Expansion
Clinical pipeline expanded with the in-licensing of AMT-143, a novel long-acting formulation of bupivacaine. The company also reported progress in its Phase II study of PCRX-201 for osteoarthritis of the knee.
Market Access and Coverage
The company is ahead of plan to surpass the full-year goal of 100 million covered lives across commercial and government payers. Approximately 60 million commercial lives now have access to EXPAREL via separate reimbursement.
Cash Flow and Shareholder Returns
Significant operating cash flow and a strong balance sheet enable investments in new growth initiatives. The company executed an additional $50 million in share repurchases during the quarter.
Negative Updates
Zilretta Sales
Zilretta sales were slower than anticipated, with only a slight increase to $29.0 million from $28.4 million in 2024.
GPO Discount Impact
Discounting from the third GPO agreement resulted in a higher-than-expected single-digit year-over-year impact on net selling prices.
Elective Procedure Market
Elective procedures were sluggish in the first half of the year, and while there were modest improvements in the third quarter, the growth was not monumental.
Company Guidance
During the Pacira BioSciences third quarter 2025 earnings call, the company provided several key performance metrics and guidance. Year-over-year revenues increased by 6%, driven by a 9% rise in EXPAREL demand, marking the highest quarterly growth in over three years. The company reported EXPAREL sales of $139.9 million, Zilretta sales of $29.0 million, and iovera sales of $6.5 million for the third quarter. Non-GAAP gross margins improved to 82%, compared to 78% the previous year, with the guidance for full-year revenues narrowed to $725 million to $735 million. The company also highlighted its strategic initiatives, such as the in-licensing of AMT-143, a novel long-acting formulation of bupivacaine, and emphasized its robust patent protection with the listing of the 21st EXPAREL patent in the FDA's Orange Book. With significant cash flows, a strong balance sheet, and strategic share repurchases totaling $50 million, Pacira BioSciences is well-positioned to advance its 5x30 growth strategy, aiming for a five-year double-digit compound annual growth rate (CAGR) for revenue.

Pacira Pharmaceuticals Financial Statement Overview

Summary
Solid overall fundamentals supported by strong cash generation (FCF growth 6.1% TTM; OCF/NI 1.32) and a very low debt-to-equity ratio (0.013 TTM). Offsetting this, profitability remains modest (net margin 4.13%) and revenue growth is only incremental (1.55% TTM).
Income Statement
68
Positive
Pacira Pharmaceuticals shows a modest revenue growth rate of 1.55% TTM, with a stable gross profit margin of 58.9%. However, the net profit margin is relatively low at 4.13%, indicating limited profitability. The EBIT and EBITDA margins have improved over the previous year, suggesting better operational efficiency.
Balance Sheet
72
Positive
The company has significantly reduced its debt-to-equity ratio to 0.013 TTM, indicating strong financial stability. The return on equity is modest at 3.87%, reflecting moderate profitability. The equity ratio is healthy, showing a solid capital structure.
Cash Flow
75
Positive
Pacira Pharmaceuticals has achieved a free cash flow growth rate of 6.1% TTM, demonstrating strong cash generation capabilities. The operating cash flow to net income ratio is robust at 1.32, indicating efficient cash conversion. The free cash flow to net income ratio is also strong at 0.88.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue716.79M700.97M674.98M666.82M541.53M429.65M
Gross Profit567.46M530.54M490.31M467.53M401.28M312.32M
EBITDA147.82M29.12M154.59M140.38M113.95M63.51M
Net Income21.44M-99.56M41.95M15.91M41.98M145.52M
Balance Sheet
Total Assets1.30B1.55B1.57B1.68B2.08B1.27B
Cash, Cash Equivalents and Short-Term Investments246.33M484.62M278.58M288.65M656.41M521.66M
Total Debt425.31M638.85M586.04M763.39M1.13B541.13M
Total Liabilities570.36M775.17M704.26M906.19M1.34B654.83M
Stockholders Equity727.21M778.35M870.13M775.01M730.41M619.69M
Cash Flow
Free Cash Flow124.20M178.75M139.49M115.20M79.85M39.23M
Operating Cash Flow141.44M189.39M154.65M145.27M125.72M77.03M
Investing Cash Flow79.78M-83.28M77.54M-225.19M-20.79M-277.61M
Financing Cash Flow-319.93M17.36M-183.03M-401.53M380.69M222.30M

Pacira Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price20.54
Price Trends
50DMA
23.76
Negative
100DMA
23.82
Negative
200DMA
24.26
Negative
Market Momentum
MACD
-1.23
Positive
RSI
39.41
Neutral
STOCH
57.56
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PCRX, the sentiment is Negative. The current price of 20.54 is below the 20-day moving average (MA) of 21.97, below the 50-day MA of 23.76, and below the 200-day MA of 24.26, indicating a bearish trend. The MACD of -1.23 indicates Positive momentum. The RSI at 39.41 is Neutral, neither overbought nor oversold. The STOCH value of 57.56 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for PCRX.

Pacira Pharmaceuticals Risk Analysis

Pacira Pharmaceuticals disclosed 69 risk factors in its most recent earnings report. Pacira Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Pacira Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
79
Outperform
$1.22B11.7514.84%-0.03%-27.66%
72
Outperform
$1.45B28.5822.96%26.34%-32.79%
66
Neutral
$1.84B50.207.83%48.87%
64
Neutral
$883.66M46.042.90%3.14%
57
Neutral
$2.11B-3,918.18-0.32%79.88%99.60%
55
Neutral
$2.76B-141.31-1.86%4.54%-130.59%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PCRX
Pacira Pharmaceuticals
20.54
-5.21
-20.23%
AVDL
Avadel Pharmaceuticals
21.55
13.58
170.39%
SUPN
Supernus Pharmaceuticals
48.16
10.80
28.91%
ANIP
ANI Pharmaceuticals
81.85
23.94
41.34%
AMPH
Amphastar Pharmaceuticals
26.49
-6.90
-20.66%
COLL
Collegium Pharmaceutical
45.92
14.72
47.18%

Pacira Pharmaceuticals Corporate Events

Business Operations and StrategyExecutive/Board Changes
Pacira BioSciences adds seasoned leader to board
Positive
Jan 28, 2026

On January 27, 2026, Pacira BioSciences expanded its Board of Directors from nine to 10 members and appointed veteran biopharmaceutical executive Samit Hirawat, M.D., as a Class III director and member of the Science and Technology Committee, with the appointment announced publicly on January 28, 2026. The addition of Hirawat, an independent director with more than 25 years of clinical development and leadership experience at Bristol Myers Squibb and Novartis, underscores Pacira’s efforts to strengthen its governance and scientific oversight as it seeks to accelerate growth of its non-opioid pain portfolio and advance its pipeline, including next-generation gene therapies, potentially bolstering its competitive position in the non-opioid pain management market.

The most recent analyst rating on (PCRX) stock is a Buy with a $38.00 price target. To see the full list of analyst forecasts on Pacira Pharmaceuticals stock, see the PCRX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 29, 2026