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LFSC - ETF AI Analysis

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LFSC

F/M Emerald Life Sciences Innovation ETF (LFSC)

Rating:55Neutral
Price Target:
LFSC, the F/M Emerald Life Sciences Innovation ETF, has a middling overall rating that reflects a mix of promising growth stories and significant financial risk among its holdings. Strong contributors like TransMedics Group, with robust revenue growth, positive earnings sentiment, and strategic acquisitions, help support the fund’s quality, while several holdings such as Cogent Biosciences and KalVista Pharmaceuticals face serious financial challenges and weak valuations that drag on the rating. The main risk is the fund’s focus on life sciences companies that often have negative profitability, high cash burn, and valuation concerns, making it more volatile and dependent on future clinical and regulatory successes.
Positive Factors
Strong Recent Three-Month Performance
The ETF has shown solid gains over the last three months, suggesting recent momentum despite short-term pullbacks.
Several Strong-Performing Top Holdings
Key positions like Cogent Biosciences, Guardant Health, TransMedics Group, and Mirum Pharmaceuticals have delivered strong year-to-date performance, helping support the fund’s results.
Focused Exposure to U.S. Life Sciences
The fund is heavily invested in U.S. health care and life sciences companies, giving targeted exposure to a specialized innovation theme.
Negative Factors
Recent Short-Term Weakness
The ETF has experienced weak one-month and year-to-date performance, which may concern investors sensitive to near-term declines.
High Concentration in a Single Sector
With almost all assets in health care and life sciences, the fund is vulnerable to downturns or regulatory changes affecting that sector.
Mixed Performance Among Top Holdings
Several sizable positions, such as Wave Life Sciences and Travere Therapeutics, have lagged year-to-date, creating a drag on overall performance.

LFSC vs. SPDR S&P 500 ETF (SPY)

LFSC Summary

The F/M Emerald Life Sciences Innovation ETF (LFSC) is a fund that focuses on innovative health care companies, mainly in pharmaceuticals, biotechnology, and life sciences. It does not track a traditional index, but instead selects U.S.-based firms working on new drugs, medical treatments, and health technologies. Top holdings include companies like Guardant Health and TransMedics Group, which are involved in advanced diagnostics and organ transplant technologies. Investors might consider LFSC if they want growth potential from cutting-edge medical breakthroughs and added diversification within health care. However, this ETF is concentrated in a single, high-risk sector, so its price can be very volatile and may swing sharply up or down.
How much will it cost me?The F/M Emerald Life Sciences Innovation ETF (LFSC) has an expense ratio of 0.54%, meaning you’ll pay $5.40 per year for every $1,000 invested. This is slightly higher than average because it’s actively managed, focusing on specialized companies in the Pharma, Biotech & Life Sciences sector to capture unique growth opportunities.
What would affect this ETF?The LFSC ETF, focused on U.S.-based pharmaceutical, biotech, and life sciences companies, could benefit from advancements in medical technology, increased healthcare spending, and favorable regulatory approvals for new treatments. However, it may face challenges from rising interest rates, which can impact funding for innovation, and regulatory hurdles that could delay drug approvals or increase costs for its top holdings. Economic downturns or reduced government healthcare budgets could also negatively affect the sector.

LFSC Top 10 Holdings

LFSC is a pure play on U.S. life sciences, with nearly all its firepower aimed at smaller pharma and biotech names. TransMedics Group and Mirum Pharmaceuticals are among the key engines, with rising share prices helping pull the fund higher alongside a strong run from Guardant Health. On the flip side, Wave Life Sciences and Travere Therapeutics have been lagging, occasionally acting like a brake on performance. Cogent Biosciences is more of a wild card, reflecting the fund’s willingness to embrace high-risk, high-reward innovators.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Cogent Biosciences8.85%$8.00M$5.46B285.71%
37
Underperform
LivaNova6.81%$6.16M$3.59B27.78%
63
Neutral
Guardant Health5.63%$5.09M$14.75B142.74%
61
Neutral
Mirum Pharmaceuticals5.45%$4.93M$5.33B111.17%
56
Neutral
TransMedics Group5.08%$4.59M$4.58B105.73%
77
Outperform
Travere Therapeutics5.02%$4.53M$2.78B51.97%
56
Neutral
Wave Life Sciences4.89%$4.42M$2.37B12.44%
67
Neutral
BridgeBio Pharma3.98%$3.60M$14.89B119.90%
59
Neutral
Savara3.78%$3.41M$1.10B106.67%
46
Neutral
KalVista Pharmaceuticals3.69%$3.34M$789.03M75.64%
45
Neutral

LFSC Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price
Price Trends
50DMA
37.03
Negative
100DMA
33.82
Positive
200DMA
29.20
Positive
Market Momentum
MACD
-0.27
Positive
RSI
42.35
Neutral
STOCH
12.29
Positive
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For LFSC, the sentiment is Neutral. The current price of undefined is equal to the 20-day moving average (MA) of 36.23, equal to the 50-day MA of 37.03, and equal to the 200-day MA of 29.20, indicating a neutral trend. The MACD of -0.27 indicates Positive momentum. The RSI at 42.35 is Neutral, neither overbought nor oversold. The STOCH value of 12.29 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for LFSC.

LFSC Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$89.96M0.54%
$90.69M0.85%
$75.52M1.06%
$54.19M0.65%
$50.37M0.32%
$48.80M0.75%
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LFSC
F/M Emerald Life Sciences Innovation ETF
35.64
9.79
37.87%
CEPI
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GPTY
YieldMax AI & Tech Portfolio Option Income ETF
XPND
First Trust Expanded Technology ETF
GABF
Gabelli Financial Services Opportunities ETF
SRHR
SRH REIT Covered Call ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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