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Travere Therapeutics (TVTX)
NASDAQ:TVTX
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Travere Therapeutics (TVTX) AI Stock Analysis

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TVTX

Travere Therapeutics

(NASDAQ:TVTX)

Rating:49Neutral
Price Target:
$17.50
▼(-25.44% Downside)
Travere Therapeutics' overall stock score is primarily influenced by its financial performance challenges, including high debt levels and negative cash flows. While the earnings call provided positive insights into product performance and strategic progress, the company's valuation remains unattractive due to ongoing losses. Technical indicators suggest a neutral market sentiment, with no strong momentum in either direction.
Positive Factors
Revenue Growth
Strong revenue growth indicates robust demand for Travere's products, enhancing its market position and supporting long-term financial health.
Regulatory Approval
The FDA's approval of updated REMS labeling for FILSPARI reduces monitoring burdens, potentially increasing patient adherence and expanding market reach.
Product Pipeline
The potential approval of FILSPARI for FSGS could establish Travere as a leader in treating this rare disease, opening new revenue streams.
Negative Factors
High Debt Levels
Significant leverage poses financial risks, potentially limiting Travere's ability to invest in growth opportunities and manage economic downturns.
Profitability Challenges
Ongoing losses and negative margins highlight profitability issues, which could affect Travere's ability to sustain operations without external funding.
Cash Flow Concerns
Negative cash flows indicate cash burn, which may pressure Travere's liquidity and necessitate additional financing to support operations.

Travere Therapeutics (TVTX) vs. SPDR S&P 500 ETF (SPY)

Travere Therapeutics Business Overview & Revenue Model

Company DescriptionTravere Therapeutics, Inc., a biopharmaceutical company, focuses on the identification, development, commercialization, and delivering of therapies for the treatment of rare diseases. Its marketed products include Chenodal, a synthetic oral form of chenodeoxycholic acid for the treatment of radiolucent stones in gallbladders; Cholbam, a cholic acid capsule to treat pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects, as well as for adjunctive treatment of patients with peroxisomal disorders; and Thiola and Thiola EC, a tiopronin tablet for the treatment of homozygous cystinuria. The company's product candidates also consist of Sparsentan, which is in Phase III clinical trial for the treatment of focal segmental glomerulosclerosis and immunoglobulin A nephropathy; and TVT-058, a novel investigational human enzyme replacement candidate, which is in Phase I/II clinical trials for the treatment of classical homocystinuria. It has a cooperative research and development agreement with National Institutes of Health's National Center for Advancing Translational Sciences and patient advocacy organizations, CDG Care, and Alagille Syndrome Alliance for the identification of potential small molecule therapeutics for NGLY1 deficiency and Alagille syndrome. The company was formerly known as Retrophin, Inc. and changed its name to Travere Therapeutics, Inc. in November 2020. Travere Therapeutics, Inc. was incorporated in 2008 and is headquartered in San Diego, California.
How the Company Makes MoneyTravere Therapeutics generates revenue primarily through the sale of its approved pharmaceutical products, particularly Filspari, which is marketed for the treatment of IgA nephropathy. The company also earns revenue through collaborations and partnerships with other pharmaceutical companies, which may include milestone payments and royalties based on the sales of products developed in conjunction with these partners. Additionally, Travere may receive funding through grants and research contracts aimed at supporting its drug development initiatives.

Travere Therapeutics Earnings Call Summary

Earnings Call Date:Aug 06, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Nov 05, 2025
Earnings Call Sentiment Positive
The earnings call highlighted strong financial and commercial performance, particularly for FILSPARI in IgA nephropathy, and positive clinical data supporting its efficacy. Strategic advancements in expanding FILSPARI's indications and robust pipeline development were emphasized. However, increased SG&A expenses and potential generic competition for THIOLA products were noted as challenges. Overall, the positive developments surpassed the lowlights.
Q2-2025 Updates
Positive Updates
Strong Performance in IgA Nephropathy
FILSPARI delivered the strongest commercial quarter to date with $72 million in net product sales in the U.S., representing significant year-over-year growth. There was a 43% increase in new patient start forms compared to the same period last year.
Positive Clinical Data for FILSPARI
In the Phase II SPARTAN trial, FILSPARI-treated patients achieved approximately 70% proteinuria reduction, with nearly 60% reaching complete proteinuria remission and stable eGFR through 24 weeks.
Financial Growth and Milestone Achievement
Net product sales grew approximately 82% over the same period last year to $94.8 million. A $17.5 million milestone payment was received from CSL Vifor following full approval in Europe.
Strategic Pipeline Advancements
Preparations are underway for the potential expansion of FILSPARI into FSGS, with an sNDA review process for a second indication advancing as expected.
Negative Updates
Increased SG&A Expenses
Selling, general, and administrative expenses increased to $76.2 million from $64.8 million in the same period last year, largely due to increased amortization expense and launch investments.
Potential Generic Competition
THIOLA and THIOLA EC, contributing $23 million in net product sales, are anticipated to face more generic competition in the coming quarters.
Company Guidance
In the Travere Therapeutics Second Quarter 2025 Financial Results Conference Call, significant metrics underscored the company's robust performance and strategic progress. FILSPARI, their key product, achieved net product sales of approximately $72 million in the U.S., marking strong year-over-year growth. The company reported total Q2 revenue of $114.4 million, including $19.6 million from license and collaboration, driven in part by a $17.5 million milestone payment from CSL Vifor. Their financial strength is further supported by a cash balance of approximately $319.5 million as of June 30, 2025. The company experienced an approximately 82% increase in net product sales compared to the same period last year. With a non-GAAP adjusted net income of $11.9 million, Travere is poised for sustained growth, driven by FILSPARI's expanding market presence and potential regulatory milestones for its application in FSGS, with a PDUFA date set for January 13, 2026.

Travere Therapeutics Financial Statement Overview

Summary
Travere Therapeutics demonstrates strong revenue growth and gross profit margins, but faces significant profitability and leverage challenges. The high debt levels and negative cash flows pose financial risks, requiring careful management to achieve sustainable growth and profitability.
Income Statement
45
Neutral
Travere Therapeutics shows a strong gross profit margin of 92.69% TTM, indicating efficient cost management. However, the company faces challenges with negative net profit and EBIT margins, reflecting ongoing losses. Revenue growth is positive at 22.06% TTM, suggesting potential for future improvement, but the consistent negative margins highlight profitability issues.
Balance Sheet
30
Negative
The company has a high debt-to-equity ratio of 12.20 TTM, indicating significant leverage and potential financial risk. Return on equity is negative, reflecting ongoing losses and challenges in generating shareholder value. The equity ratio is low, suggesting limited equity financing relative to total assets.
Cash Flow
40
Negative
Operating cash flow and free cash flow are both negative, indicating cash burn. However, the free cash flow to net income ratio is above 1, suggesting that cash outflows are somewhat aligned with accounting losses. The negative free cash flow growth rate of -32.51% TTM highlights increasing cash flow challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue333.87M233.18M145.24M212.02M227.49M198.32M
Gross Profit309.47M225.43M133.79M204.43M220.71M192.19M
EBITDA-124.53M-265.77M-326.25M-299.42M-186.68M-143.95M
Net Income-169.06M-321.55M-111.40M-278.48M-180.09M-169.43M
Balance Sheet
Total Assets555.31M594.13M788.91M672.59M776.63M607.44M
Cash, Cash Equivalents and Short-Term Investments319.54M370.70M566.85M450.25M552.88M361.59M
Total Debt399.57M401.58M404.78M407.49M261.99M215.34M
Total Liabilities522.56M535.05M588.10M629.73M474.52M396.23M
Stockholders Equity32.75M59.08M200.81M42.85M302.11M211.21M
Cash Flow
Free Cash Flow-118.28M-338.69M-322.28M-214.85M-38.94M-162.59M
Operating Cash Flow-115.44M-237.47M-280.02M-186.29M-14.79M-42.74M
Investing Cash Flow11.96M99.33M55.78M-32.55M-137.62M-61.33M
Financing Cash Flow144.36M139.42M218.75M117.57M231.68M127.71M

Travere Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price23.47
Price Trends
50DMA
17.67
Positive
100DMA
17.28
Positive
200DMA
18.15
Positive
Market Momentum
MACD
1.90
Negative
RSI
64.08
Neutral
STOCH
69.95
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TVTX, the sentiment is Positive. The current price of 23.47 is above the 20-day moving average (MA) of 19.77, above the 50-day MA of 17.67, and above the 200-day MA of 18.15, indicating a bullish trend. The MACD of 1.90 indicates Negative momentum. The RSI at 64.08 is Neutral, neither overbought nor oversold. The STOCH value of 69.95 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for TVTX.

Travere Therapeutics Risk Analysis

Travere Therapeutics disclosed 59 risk factors in its most recent earnings report. Travere Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Travere Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
68
Neutral
$1.78B-5.38%26.90%62.72%
65
Neutral
$2.54B-20.95%
51
Neutral
$7.92B-0.36-43.38%2.24%22.38%-2.16%
49
Neutral
$2.23B-705.73%87.94%57.84%
48
Neutral
$1.69B18.68%45.85%76.36%
43
Neutral
$2.08B-26.36%-22.19%
39
Underperform
$1.57B-54.83%-62.51%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TVTX
Travere Therapeutics
23.47
9.20
64.47%
BCRX
BioCryst
7.91
0.00
0.00%
IRON
Disc Medicine
59.82
12.14
25.46%
IMCR
Immunocore Holdings
35.24
2.24
6.79%
VERA
Vera Therapeutics
23.77
-16.33
-40.72%
CGON
CG Oncology, Inc.
33.34
-3.66
-9.89%

Travere Therapeutics Corporate Events

Executive/Board ChangesShareholder Meetings
Travere Therapeutics Holds Annual Meeting, Elects Directors
Neutral
May 16, 2025

On May 15, 2025, Travere Therapeutics held its Annual Meeting where stockholders voted on several proposals. The company elected ten directors to serve until the 2026 Annual Meeting, approved an amendment to increase shares under the 2018 Equity Incentive Plan, approved executive compensation, and ratified Ernst & Young LLP as the independent auditor for the fiscal year ending December 31, 2025. These decisions reflect the company’s ongoing governance and strategic planning efforts.

The most recent analyst rating on (TVTX) stock is a Buy with a $16.00 price target. To see the full list of analyst forecasts on Travere Therapeutics stock, see the TVTX Stock Forecast page.

Product-Related AnnouncementsRegulatory Filings and Compliance
Travere Therapeutics’ FDA Acceptance for FILSPARI Application
Positive
May 15, 2025

On May 15, 2025, Travere Therapeutics announced that the FDA accepted its supplemental New Drug Application for FILSPARI® (sparsentan) for treating focal segmental glomerulosclerosis (FSGS), with a target action date set for January 13, 2026. If approved, FILSPARI could become the first FDA-approved treatment for FSGS, a rare kidney disorder affecting over 40,000 patients in the U.S. The application is supported by the Phase 3 DUPLEX Study and Phase 2 DUET Study, which demonstrated significant benefits in reducing proteinuria and improving remission rates in FSGS patients.

The most recent analyst rating on (TVTX) stock is a Buy with a $16.00 price target. To see the full list of analyst forecasts on Travere Therapeutics stock, see the TVTX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 01, 2025