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HELX - ETF AI Analysis

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HELX

Franklin Genomic Advancements ETF (HELX)

Rating:60Neutral
Price Target:
HELX, the Franklin Genomic Advancements ETF, has a solid but not top-tier rating, reflecting a mix of strong leaders and some weaker names in its portfolio. High-quality holdings like Krystal Biotech, AstraZeneca, Vertex Pharmaceuticals, United Therapeutics, and Medpace support the fund with robust financial performance, positive earnings calls, and promising growth pipelines, though some show signs of rich valuations or overbought conditions. On the other hand, holdings such as Insmed and BridgeBio face profitability, cash flow, and valuation challenges, and the fund’s focus on genomics and biotech means investors are exposed to sector-specific risks like regulatory changes, high valuations, and clinical or competitive setbacks.
Positive Factors
Strong Recent Performance
The ETF has shown solid gains over the past three months and year-to-date, indicating positive recent momentum.
Leading Holdings Showing Strength
Several of the largest positions, such as Guardant Health, Krystal Biotech, and Adaptive Biotechnologies, have delivered strong year-to-date performance, helping support the fund’s returns.
Focused Exposure to Genomics and Health Care
With most assets in health care and genomic-related companies, the fund gives targeted access to a specialized growth area in the market.
Negative Factors
High Sector Concentration
Over 90% of the portfolio is in health care, so the ETF is heavily exposed to swings in that single sector.
Limited Geographic Diversification
The fund is invested almost entirely in U.S. companies, offering very little exposure to other countries’ markets.
Mixed Performance Among Top Holdings
Some key positions, including Insmed, United Therapeutics, and Alnylam Pharma, have shown weak year-to-date performance, which can drag on overall returns.

HELX vs. SPDR S&P 500 ETF (SPY)

HELX Summary

The Franklin Genomic Advancements ETF (HELX) focuses on companies working in genetic research and advanced healthcare, rather than tracking a traditional market index. It invests mainly in U.S. health care and biotech firms that use DNA and gene-based technologies to develop new tests and treatments, including names like Guardant Health and Natera. Someone might consider HELX if they want growth potential from the future of medicine and a basket of different genomic companies instead of picking single stocks. A key risk is that biotech and genomic stocks can be very volatile and may rise or fall sharply.
How much will it cost me?The Franklin Genomic Advancements ETF (HELX) has an expense ratio of 0.5%, meaning you’ll pay $5 per year for every $1,000 invested. This is higher than average because it is actively managed, focusing on a specialized niche in genomic advancements, which requires more research and expertise compared to passively managed funds.
What would affect this ETF?The Franklin Genomic Advancements ETF (HELX) could benefit from growing interest in personalized medicine and advancements in genetic research, as well as increased healthcare spending globally. However, it may face challenges from regulatory hurdles in biotechnology, potential setbacks in clinical trials, and broader economic pressures that could impact funding for innovation. Its heavy focus on healthcare and genomic advancements makes it sensitive to both breakthroughs and disruptions in this niche sector.

HELX Top 10 Holdings

HELX is a pure play on genomic medicine, with the portfolio heavily tilted toward health-care innovators rather than broad tech or materials names, and a global mix led by U.S. biotech. United Therapeutics and Ligand Pharma are two of the brighter spots, rising on solid financial results and upbeat outlooks, helping to steady the fund. Krystal Biotech and Vertex are more mixed, not hurting but not propelling returns either. The real drag comes from Natera, Guardant Health, Insmed, and Adaptive Biotechnologies, where weak recent trading and profitability worries are weighing on performance.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Guardant Health6.54%$1.33M$11.76B125.22%
61
Neutral
Natera6.41%$1.30M$29.04B48.18%
73
Outperform
Krystal Biotech5.33%$1.08M$7.65B57.70%
80
Outperform
United Therapeutics4.32%$878.35K$24.53B91.84%
79
Outperform
Insmed4.24%$861.92K$35.31B152.13%
43
Neutral
BridgeBio Pharma4.18%$849.78K$14.01B135.67%
59
Neutral
Ligand Pharma3.65%$741.65K$4.06B104.82%
60
Neutral
AstraZeneca3.33%$676.24K$313.97B52.31%
80
Outperform
Vertex Pharmaceuticals3.06%$621.46K$110.33B-8.48%
78
Outperform
Medpace Holdings2.95%$598.74K$14.16B70.98%
79
Outperform

HELX Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price
Price Trends
50DMA
34.11
Negative
100DMA
35.41
Negative
200DMA
32.76
Positive
Market Momentum
MACD
-0.31
Negative
RSI
51.86
Neutral
STOCH
94.31
Negative
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For HELX, the sentiment is Neutral. The current price of undefined is equal to the 20-day moving average (MA) of 32.50, equal to the 50-day MA of 34.11, and equal to the 200-day MA of 32.76, indicating a neutral trend. The MACD of -0.31 indicates Negative momentum. The RSI at 51.86 is Neutral, neither overbought nor oversold. The STOCH value of 94.31 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for HELX.

HELX Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$21.67M0.50%
60
Neutral
$95.78M0.50%
72
Outperform
$95.74M0.65%
68
Neutral
$90.02M1.00%
68
Neutral
$89.01M0.50%
57
Neutral
$87.68M0.75%
71
Outperform
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HELX
Franklin Genomic Advancements ETF
33.26
7.43
28.77%
FDCF
Fidelity Disruptive Communications ETF
TCAI
Tortoise AI Infrastructure ETF
FFND
Future Fund Active ETF
CSNR
Cohen & Steers Natural Resources Active ETF
AIFD
TCW Artificial Intelligence ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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