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HELX - ETF AI Analysis

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HELX

Franklin Genomic Advancements ETF (HELX)

Rating:61Neutral
Price Target:
HELX, the Franklin Genomic Advancements ETF, has a solid but not top-tier rating, reflecting a mix of strong leaders and some weaker names in its portfolio. High-quality holdings like Krystal Biotech, AstraZeneca, Vertex Pharmaceuticals, and United Therapeutics support the fund with robust financial performance, positive earnings calls, and promising growth pipelines. However, holdings such as Insmed and Adaptive Biotechnologies, which face profitability, cash flow, and valuation challenges, weigh on the overall rating, and the fund’s focus on genomics and biotech means investors are exposed to sector-specific volatility and regulatory risk.
Positive Factors
Focused Genomics Exposure
The fund concentrates on genomic and advanced health care companies, giving investors targeted access to a specialized growth area.
Several Strong Top Holdings
Some of the largest positions, such as Krystal Biotech, United Therapeutics, Ligand Pharma, and AstraZeneca, have shown strong year-to-date performance, helping support the ETF’s returns.
Reasonable Fund Size
With tens of millions in assets under management, the ETF is large enough to be established but still focused on its niche strategy.
Negative Factors
High Sector Concentration
Nearly all assets are in health care, so the fund is heavily exposed to swings in one industry.
Weak Recent Performance
The ETF has delivered negative results so far this year and over the last three months, showing recent performance has been weak.
Several Lagging Key Holdings
Some major positions like Natera, Guardant Health, Insmed, Adaptive Biotechnologies, and Medpace have posted weak year-to-date performance, which can drag on overall returns.

HELX vs. SPDR S&P 500 ETF (SPY)

HELX Summary

Franklin Genomic Advancements ETF (HELX) is a health care–focused fund that invests in companies working with genetic research and DNA-based medicine. It follows the theme of genomic advancements rather than a traditional market index, aiming to benefit from progress in areas like genetic testing and personalized treatments. The fund holds both specialists and big names such as AstraZeneca, giving investors a way to spread their money across many genomic innovators instead of picking single stocks. A key risk is that it’s heavily concentrated in biotech and can be very volatile, going up or down sharply with news and market sentiment.
How much will it cost me?The Franklin Genomic Advancements ETF (HELX) has an expense ratio of 0.5%, meaning you’ll pay $5 per year for every $1,000 invested. This is higher than average because it is actively managed, focusing on a specialized niche in genomic advancements, which requires more research and expertise compared to passively managed funds.
What would affect this ETF?The Franklin Genomic Advancements ETF (HELX) could benefit from growing interest in personalized medicine and advancements in genetic research, as well as increased healthcare spending globally. However, it may face challenges from regulatory hurdles in biotechnology, potential setbacks in clinical trials, and broader economic pressures that could impact funding for innovation. Its heavy focus on healthcare and genomic advancements makes it sensitive to both breakthroughs and disruptions in this niche sector.

HELX Top 10 Holdings

HELX is a pure play on genomic medicine, and its fate is tied closely to a handful of high‑octane biotech names. United Therapeutics and Krystal Biotech have been doing the heavy lifting lately, with steady-to-rising share prices that help offset turbulence elsewhere. Ligand Pharma has also been a quiet engine of gains. On the flip side, Natera, Guardant Health, and Adaptive Biotechnologies have been lagging, acting like a headwind for the fund. With most holdings in health care and a global mix led by U.S. names, this ETF is highly concentrated in cutting-edge, higher-risk innovators.
Name
Company Name
Weight %
Market Value
Market Cap
Yearly Gain
Overall Rating
Natera6.66%$1.46M$28.88B33.60%
73
Outperform
Guardant Health6.36%$1.39M$11.66B84.41%
61
Neutral
Krystal Biotech5.51%$1.21M$8.02B60.70%
80
Outperform
United Therapeutics4.35%$952.54K$24.86B90.88%
79
Outperform
Ligand Pharma4.19%$917.35K$4.61B122.07%
60
Neutral
BridgeBio Pharma4.15%$908.55K$14.21B107.63%
59
Neutral
Insmed3.69%$806.63K$29.18B94.65%
43
Neutral
AstraZeneca3.17%$692.85K$292.69B32.74%
80
Outperform
Adaptive Biotechnologies3.13%$685.56K$2.18B82.88%
53
Neutral
Vertex Pharmaceuticals2.79%$611.32K$109.45B-14.20%
78
Outperform

HELX Technical Analysis

Technical Analysis Sentiment
Positive
Last Price
Price Trends
50DMA
33.32
Positive
100DMA
34.90
Negative
200DMA
33.37
Positive
Market Momentum
MACD
0.03
Positive
RSI
53.49
Neutral
STOCH
50.88
Neutral
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For HELX, the sentiment is Positive. The current price of undefined is equal to the 20-day moving average (MA) of 33.77, equal to the 50-day MA of 33.32, and equal to the 200-day MA of 33.37, indicating a bullish trend. The MACD of 0.03 indicates Positive momentum. The RSI at 53.49 is Neutral, neither overbought nor oversold. The STOCH value of 50.88 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for HELX.

HELX Peer Comparison

Comparison Results
Name
Price
Price Target
AUM
Expense Ratio
Overall Rating
$21.72M0.50%
61
Neutral
$98.47M1.00%
69
Neutral
$97.16M0.50%
59
Neutral
$91.72M0.50%
71
Outperform
$82.50M0.90%
59
Neutral
$52.38M0.50%
64
Neutral
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HELX
Franklin Genomic Advancements ETF
33.96
6.79
24.99%
FFND
Future Fund Active ETF
CSNR
Cohen & Steers Natural Resources Active ETF
IQM
Franklin Intelligent Machines ETF
HECO
SPDR Galaxy Hedged Digital Asset Ecosystem ETF
TEKY
Lazard Next Gen Technologies ETF
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
DisclaimerThis AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
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