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Bridgebio Pharma (BBIO)
NASDAQ:BBIO
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BridgeBio Pharma (BBIO) AI Stock Analysis

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BBIO

BridgeBio Pharma

(NASDAQ:BBIO)

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Neutral 62 (OpenAI - 5.2)
Rating:62Neutral
Price Target:
$96.00
▲(25.08% Upside)
Action:Reiterated
Date:07/10/26
BBIO’s score is held back primarily by weak financial performance (deep losses, significant cash burn, and negative equity), partially offset by strong technical momentum and a notably positive earnings narrative centered on rapid Atruvio growth, a strengthened cash position, and a stated path toward breakeven/cash-flow positivity. Valuation remains challenged due to negative earnings and no dividend support, while recent corporate developments (financing and regulatory progress) are additive but secondary.
Positive Factors
Rapid Atruvio revenue growth
Sustained, large QoQ and YoY Atruvio growth demonstrates durable commercial traction and expanding patient uptake. This revenue base can fund scale, enable operating leverage as fixed costs are spread, and underpins management's path to breakeven while supporting launches of additional pipeline assets.
Negative Factors
Large ongoing cash burn and negative FCF
Persistent negative operating and free cash flow indicate the business remains cash‑consumptive absent sustained commercial scale. Continued burn elevates dependency on external financing, risks dilution, and constrains discretionary investment if revenues slow or launch costs run higher than planned.
Read all positive and negative factors
Positive Factors
Negative Factors
Rapid Atruvio revenue growth
Sustained, large QoQ and YoY Atruvio growth demonstrates durable commercial traction and expanding patient uptake. This revenue base can fund scale, enable operating leverage as fixed costs are spread, and underpins management's path to breakeven while supporting launches of additional pipeline assets.
Read all positive factors

BridgeBio Pharma Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Highlights how much revenue each business segment generates, providing insight into which areas are driving growth and which may need strategic adjustments.
Chart InsightsBridgeBio’s revenue mix shifted in 2025 from lumpy license-and-services receipts to recurring net-product sales driven by Atruby’s rapid commercial ramp; this materially de-risks near-term top-line but concentrates current revenue in one product, leaving near-term volatility from one-time license spikes. Management’s reported QoQ acceleration, rising prescriber reach and guidance that burn will stabilize then fall as Atruby and upcoming launches (Encalarec, BBP-418) ramp makes the company more likely to hit cash-generative targets—execution on those late-2026/2027 launches and IP/legal risks remain the key execution risks.
Data provided by:The Fly

BridgeBio Pharma (BBIO) vs. SPDR S&P 500 ETF (SPY)

BridgeBio Pharma Business Overview & Revenue Model

Company Description
BridgeBio Pharma, Inc. is a pharmaceutical company dedicated to identifying, advancing, and providing medical solutions for various genetic conditions. The firm boasts an extensive portfolio comprising 30 distinct development initiatives, spanning...
How the Company Makes Money
BridgeBio makes money primarily through (1) product sales from its commercial medicines and (2) collaboration-related income typical of biopharma companies. 1) Product sales (commercial revenue) - BridgeBio generates revenue from the sale of its ...

BridgeBio Pharma Earnings Call Summary

Earnings Call Date:May 07, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Jul 30, 2026
Earnings Call Sentiment Positive
The call conveyed strong commercial momentum (notably Atruvio revenue growth: $180.6M, +24% QoQ, +392% YoY), robust cash runway ($940.2M) and clear pipeline progress with active launch preparations (LGMD2I NDA, ADH1 patient ID, positive PROPEL‑3 for achondroplasia). Management emphasized clinical differentiation backed by real‑world evidence and favorable long‑term economics, while acknowledging short‑term expense pressures (operating expenses +$72.1M) and an operating loss of $106M that should narrow later in the year. Competitive risks, diagnostic supply issues, and the prior‑year milestone timing created some near‑term revenue volatility, but overall the company presented multiple tangible positives that outweigh the listed challenges.
Positive Updates
Atruvio Net Product Revenue Surge
Atruvio U.S. net product revenue of $180.6 million in Q1 2026, representing 24% quarter‑over‑quarter growth and 392% year‑over‑year growth; company describes brand as becoming a 2026 blockbuster with growing frontline share and >6,100 total new patient starts in the category this quarter.
Negative Updates
Sharp Decline in License & Services Revenue
License and services revenue fell to $0.4 million from $79.7 million year‑over‑year, reflecting the absence of a one‑time $75 million regulatory milestone recognized in the prior year; causes a revenue mix swing and volatility in reported top line.
Read all updates
Q1-2026 Updates
Negative
Atruvio Net Product Revenue Surge
Atruvio U.S. net product revenue of $180.6 million in Q1 2026, representing 24% quarter‑over‑quarter growth and 392% year‑over‑year growth; company describes brand as becoming a 2026 blockbuster with growing frontline share and >6,100 total new patient starts in the category this quarter.
Read all positive updates
Company Guidance
Management’s guidance emphasized continued Atruvio-driven growth and improving financial durability: Q1 total revenue was $194.5M (vs. $116.6M YoY) led by Atruvio U.S. net product revenue of $180.6M (24% q/q, +392% YoY), a $143.9M Atruvio lift that contributed to a $77.9M revenue increase overall; royalty revenue rose to $9.5M while license/services fell to $0.4M (prior-year $79.7M). They reported total operating expenses of $290.5M (SG&A $163.9M, +$57.5M; R&D $126.6M, +$15.2M), a $106M operating loss (but losses have narrowed >50% over five quarters), and $940.2M in cash and marketable securities (up from $587.5M), with guidance that losses should flatten over the next two quarters and the company expects to reach P&L breakeven and then sustainable cash-flow positivity by year‑end; the board also authorized a $500M share‑repurchase program to start immediately. Operational and pipeline metrics cited to support commercial outlook included >6,100 new patient starts in the ATTR class this quarter, a projected $4B peak for Atruvio, an IP runway of at least six years, real‑world signals such as a 43% reduction in diuretic intensification vs. tafamidis and Phase III OLE month‑54 mortality reductions (all‑cause −45%, CV −49%, p<0.0001), ~500 genetically confirmed LGMD2I U.S. patients, ~2,000 ADH1 patients identifiable via claims, achondroplasia unaided awareness >40%, and infigratinib’s 2.1 cm annualized height‑velocity benefit.

BridgeBio Pharma Financial Statement Overview

Summary
Despite improving revenue momentum and very strong gross margin (~95%), BBIO’s fundamentals are still constrained by deep losses (TTM net margin ~-128%), substantial cash burn (TTM FCF about -$454M, with deterioration vs. prior period), and a pressured capital structure with sizable negative equity (about -$2.27B). Overall, the company appears to be scaling commercial revenue but has not yet demonstrated self-funding operations in the reported statements.
Income Statement
28
Negative
Balance Sheet
18
Very Negative
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue579.96M502.08M221.90M9.30M77.65M69.72M
Gross Profit543.90M473.81M218.02M6.86M74.21M66.60M
EBITDA-608.84M-672.88M-436.83M-565.47M-397.44M-533.83M
Net Income-725.93M-729.31M-535.76M-643.20M-481.18M-562.54M
Balance Sheet
Total Assets1.37B936.02M919.34M546.38M623.04M1.01B
Cash, Cash Equivalents and Short-Term Investments940.19M587.48M681.10M434.88M471.92M836.66M
Total Debt3.38B2.73B1.73B1.74B1.72B1.73B
Total Liabilities3.64B3.01B2.38B1.89B1.87B1.88B
Stockholders Equity-2.27B-2.08B-1.47B-1.35B-1.25B-870.41M
Cash Flow
Free Cash Flow-454.12M-447.01M-521.66M-529.03M-425.81M-546.18M
Operating Cash Flow-443.95M-445.91M-520.73M-527.72M-419.49M-497.93M
Investing Cash Flow-65.03M-24.49M60.78M54.03M453.15M-200.83M
Financing Cash Flow848.26M359.29M748.46M451.54M-13.13M736.45M

BridgeBio Pharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price76.75
Price Trends
50DMA
69.36
Positive
100DMA
70.42
Positive
200DMA
68.99
Positive
Market Momentum
MACD
3.65
Negative
RSI
86.79
Negative
STOCH
88.38
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BBIO, the sentiment is Positive. The current price of 76.75 is above the 20-day moving average (MA) of 71.96, above the 50-day MA of 69.36, and above the 200-day MA of 68.99, indicating a bullish trend. The MACD of 3.65 indicates Negative momentum. The RSI at 86.79 is Negative, neither overbought nor oversold. The STOCH value of 88.38 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BBIO.

BridgeBio Pharma Risk Analysis

BridgeBio Pharma disclosed 101 risk factors in its most recent earnings report. BridgeBio Pharma reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BridgeBio Pharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
85
Outperform
$14.35B18.1740.21%3.33%38.64%
71
Outperform
$11.59B42.324.41%12.53%-49.09%
62
Neutral
$17.68B-22.8936.00%355.17%-6.09%
60
Neutral
$30.38B-8.40-36.73%-29.97%6.60%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$10.62B-29.29-58.57%47.40%32.85%
49
Neutral
$12.91B-41.66-50.15%256.82%29.06%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BBIO
BridgeBio Pharma
85.89
39.42
84.83%
BMRN
BioMarin Pharmaceutical
59.12
1.02
1.76%
EXEL
Exelixis
56.50
11.64
25.95%
IONS
Ionis Pharmaceuticals
58.25
16.52
39.59%
MDGL
Madrigal Pharmaceuticals
536.70
221.24
70.13%
MRNA
Moderna
68.27
34.63
102.94%

BridgeBio Pharma Corporate Events

Business Operations and StrategyPrivate Placements and Financing
BridgeBio Raises $934 Million via Preferred Equity Financing
Positive
Jul 2, 2026
On July 1, 2026, BridgeBio Pharma entered into an investment agreement with funds managed by Sixth Street and HealthCare Royalty for a $933.9 million issuance of Series A Cumulative Convertible Participating Preferred Stock, with Sixth Street cont...
Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
BridgeBio shareholders approve board changes and equity plan
Positive
Jun 26, 2026
On June 22, 2026, BridgeBio Pharma held its annual meeting of stockholders, at which director Randal W. Scott resigned from the board upon completion of his term as a Class I director, with the company stating his departure did not stem from any d...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
BridgeBio Wins FDA Priority Review for BBP-418 Therapy
Positive
May 27, 2026
On May 27, 2026, BridgeBio Pharma announced that the U.S. Food and Drug Administration accepted and granted Priority Review to its New Drug Application for oral BBP-418 to treat limb-girdle muscular dystrophy type 2I/R9, with a Prescription Drug U...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
BridgeBio Files FDA NDA for Encaleret in ADH1
Positive
May 13, 2026
On May 12, 2026, BridgeBio Pharma announced it had submitted a New Drug Application to the U.S. Food and Drug Administration for encaleret as a targeted treatment for autosomal dominant hypocalcemia type 1, following positive Phase 3 CALIBRATE res...
Private Placements and FinancingRegulatory Filings and Compliance
BridgeBio Pharma Launches New $500 Million ATM Program
Neutral
May 8, 2026
On May 7, 2026, BridgeBio Pharma, Inc. filed an automatic shelf registration statement on Form S-3ASR with the U.S. Securities and Exchange Commission and entered into a new Equity Distribution Agreement with Goldman Sachs Co. LLC and Leerink Par...
Business Operations and StrategyStock BuybackFinancial Disclosures
BridgeBio Pharma Announces $500 Million Stock Repurchase Program
Positive
May 7, 2026
BridgeBio reported first-quarter 2026 revenue of $194.5 million, largely driven by $180.6 million in U.S. Attruby sales, alongside expanding real-world evidence showing significant mortality and quality-of-life benefits versus existing therapies, ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 10, 2026