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Legend Biotech Corporation (LEGN)
NASDAQ:LEGN
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Legend Biotech (LEGN) AI Stock Analysis

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LEGN

Legend Biotech

(NASDAQ:LEGN)

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Neutral 61 (OpenAI - 5.2)
Rating:61Neutral
Price Target:
$30.00
▲(41.71% Upside)
Action:Reiterated
Date:05/13/26
The score is driven by strong technical momentum and constructive earnings-call outlook (commercial growth, manufacturing execution, and a stated path to adjusted profitability in 2026). These positives are tempered by weaker underlying financial quality today—continued losses and cash burn—and limited valuation support due to negative earnings.
Positive Factors
Commercial momentum: CARVYKTI sales & global reach
Sustained, high-double-digit CARVYKTI sales growth and sequential increases reflect durable market adoption and expanding geographic footprint. That scale improves revenue visibility, funds continued commercial investment and R&D, and cements leadership in BCMA CAR-T—supporting long-term franchise economics.
Negative Factors
Negative operating and free cash flow
Despite revenue acceleration, persistent negative operating and free cash flow indicate the company hasn’t fully converted sales into cash. Continued cash burn creates ongoing funding risk and potential dilution pressure unless operational cash conversion improves consistently toward profitability and positive free cash flow.
Read all positive and negative factors
Positive Factors
Negative Factors
Commercial momentum: CARVYKTI sales & global reach
Sustained, high-double-digit CARVYKTI sales growth and sequential increases reflect durable market adoption and expanding geographic footprint. That scale improves revenue visibility, funds continued commercial investment and R&D, and cements leadership in BCMA CAR-T—supporting long-term franchise economics.
Read all positive factors

Legend Biotech Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Breaks down earnings by different business areas, highlighting which segments are driving growth and where there may be challenges or opportunities.
Chart InsightsLegend Biotech's revenue from collaboration has seen a robust upward trajectory, reflecting strategic partnerships and increased market penetration. The recent earnings call highlights CARVYKTI's strong sales growth and international expansion, which align with this revenue surge. Despite challenges like neurotoxicity and current profitability issues, the company's focus on expanding manufacturing capacity and advancing clinical trials suggests a promising outlook. The anticipated profitability of CARVYKTI by the end of 2025 and overall company profitability by 2026 could further enhance revenue streams, making Legend Biotech an attractive prospect for investors.
Data provided by:The Fly

Legend Biotech (LEGN) vs. SPDR S&P 500 ETF (SPY)

Legend Biotech Business Overview & Revenue Model

Company Description
Legend Biotech Corporation, a clinical-stage biopharmaceutical company, through its subsidiaries, engages in the discovery and development of novel cell therapies for oncology and other indications in the United States, China, and internationally....
How the Company Makes Money
Legend Biotech makes money primarily through collaboration and commercialization arrangements related to its lead product, CARVYKTI, and through research and development partnerships. Key revenue streams include: (1) Collaboration revenue: Under i...

Legend Biotech Earnings Call Summary

Earnings Call Date:May 12, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 18, 2026
Earnings Call Sentiment Positive
The call conveyed strong commercial momentum and operational performance—notably robust CARVYKTI sales growth (52% YoY), improved manufacturing metrics (99% success, 29-day turnaround), deeper earlier-line penetration (41% vs 29% YoY), a solid cash position (~$835M), and a clear path to adjusted profitability in 2026. These positives are tempered by a near-term gross margin hit (41% vs 57% prior quarter) from one-time manufacturing ramp costs, an adjusted net loss still present in Q1, event-driven uncertainty around pivotal readouts (CARTITUDE-5/6), and early-stage clinical risk for the In Vivo programs where safety/efficacy data are not yet disclosed. On balance, the highlights (strong growth, manufacturing execution, expanding pipeline, balance sheet strength, path to profitability) outweigh the lowlights, supporting a constructive view of the company's near- to mid-term outlook.
Positive Updates
Strong CARVYKTI Sales Growth
CARVYKTI net trade sales of approximately $597 million in Q1 2026, representing 52% year-over-year growth (36% U.S. YoY; >200% ex-U.S. YoY) and 8% sequential growth vs Q4 2025.
Negative Updates
Quarterly Gross Margin Compression
Gross margin on net product sales fell to 41% in Q1 from 57% in Q4 2025 (a 16 percentage-point decline) due primarily to one-time expenses tied to ramping expanded Raritan site and Tech Lane facility; company expects gross margin >50% in Q2 as scale is realized.
Read all updates
Q1-2026 Updates
Negative
Strong CARVYKTI Sales Growth
CARVYKTI net trade sales of approximately $597 million in Q1 2026, representing 52% year-over-year growth (36% U.S. YoY; >200% ex-U.S. YoY) and 8% sequential growth vs Q4 2025.
Read all positive updates
Company Guidance
Legend guided that it expects company‑wide adjusted profitability in 2026 (Q1 adjusted net loss was $11M, $0.03 per diluted share vs. a year‑ago adjusted loss of $27M, $0.07), with gross margin recovering from Q1’s 41% to >50% in Q2 and continued margin improvement and sequential quarter‑over‑quarter revenue growth through the year. Key supporting metrics: Q1 CARVYKTI net trade sales ≈ $597M (52% YoY; U.S. +36% YoY; ex‑U.S. >200% YoY; +8% sequential), total revenue $305M (collaboration revenue ~$298M; license/other ~$7M), manufacturing success rate 99% with median turnaround ~29 days and >95% on‑time order releases, availability in 18 global markets and 300+ treatment sites (148 U.S. authorized centers, ~1/3 community), cash ≈ $835M with no long‑term debt, R&D $86M and SG&A $90M. Pipeline guidance includes filing 1–2 U.S. INDs in 2026, potential initial In Vivo NHL data around mid‑year, and event‑driven readouts for CARTITUDE‑5/6 in 2026–2027.

Legend Biotech Financial Statement Overview

Summary
Improving top-line momentum and strong gross margins, but still loss-making with negative operating and free cash flow, indicating ongoing execution and funding risk until profitability and cash conversion improve.
Income Statement
52
Neutral
Balance Sheet
62
Positive
Cash Flow
38
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.03B627.24M285.14M117.00M68.83M
Gross Profit622.44M392.66M140.93M51.64M68.83M
EBITDA-107.78M-113.16M-477.87M-416.54M-392.38M
Net Income-297.58M-177.03M-518.25M-446.35M-403.58M
Balance Sheet
Total Assets1.73B1.67B1.85B1.33B1.12B
Cash, Cash Equivalents and Short-Term Investments948.60M1.12B1.31B1.03B882.39M
Total Debt413.70M350.60M328.67M284.53M122.97M
Total Liabilities723.60M629.61M597.24M586.65M353.52M
Stockholders Equity1.00B1.04B1.25B744.31M765.94M
Cash Flow
Free Cash Flow-168.04M-158.14M-416.00M-223.56M-243.87M
Operating Cash Flow-100.47M-144.03M-393.28M-201.28M-198.47M
Investing Cash Flow711.48M-850.54M92.79M-77.09M-194.98M
Financing Cash Flow-300.79K5.70M791.49M377.98M626.66M

Legend Biotech Technical Analysis

Technical Analysis Sentiment
Positive
Last Price21.17
Price Trends
50DMA
18.45
Positive
100DMA
20.51
Positive
200DMA
27.76
Negative
Market Momentum
MACD
0.47
Negative
RSI
67.19
Neutral
STOCH
86.41
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LEGN, the sentiment is Positive. The current price of 21.17 is above the 20-day moving average (MA) of 18.38, above the 50-day MA of 18.45, and below the 200-day MA of 27.76, indicating a neutral trend. The MACD of 0.47 indicates Negative momentum. The RSI at 67.19 is Neutral, neither overbought nor oversold. The STOCH value of 86.41 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for LEGN.

Legend Biotech Risk Analysis

Legend Biotech disclosed 117 risk factors in its most recent earnings report. Legend Biotech reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Legend Biotech Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$5.23B-32.35-29.22%64.66%-66.81%
60
Neutral
$11.53B-33.52-260.01%63.88%35.18%
56
Neutral
$9.31B-9.86139.66%450.60%-28.90%
54
Neutral
$224.88M-2.17-36.99%
52
Neutral
$6.26B-26.56-203.25%58.67%-11.45%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$9.70B-8.98-165.19%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LEGN
Legend Biotech
28.26
-2.82
-9.07%
CYTK
Cytokinetics
74.81
44.20
144.40%
AXSM
Axsome Therapeutics
224.03
118.36
112.01%
RYTM
Rhythm Pharmaceuticals
91.31
34.52
60.79%
RNA
Atrium Therapeutics, Inc.
13.14
-1.61
-10.92%
ABVX
Abivax SA Sponsored ADR
121.39
115.35
1909.77%

Legend Biotech Corporate Events

Legend Biotech Q1 2026 Results Show CARVYKTI-Fueled Revenue Surge and Narrowing Losses
May 12, 2026
Legend Biotech reported unaudited results for the quarter ended March 31, 2026, highlighting rapid commercial momentum for its multiple myeloma therapy CARVYKTI, which drove collaboration revenue up 61% year on year to $298.4 million and total rev...
Legend Biotech Reports Preliminary Q1 2026 CARVYKTI Sales of About $597 Million
Apr 14, 2026
On April 14, 2026, Legend Biotech reported that CARVYKTI® generated approximately $597 million in net trade sales for the quarter ended March 31, 2026, based on figures supplied by collaboration partner Janssen. The company emphasized that th...
Legend Biotech Posts 2025 CARVYKTI Profitability and Tops 10,000 Patients Treated
Mar 10, 2026
On March 10, 2026, Legend Biotech reported its fourth quarter and full-year 2025 results, highlighting CARVYKTI net trade sales of about $555 million in the quarter and $1.9 billion for the year, and announcing that more than 10,000 patients had b...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 13, 2026