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Maze Therapeutics, Inc. (MAZE)
NASDAQ:MAZE
US Market
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Maze Therapeutics, Inc. (MAZE) AI Stock Analysis

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MAZE

Maze Therapeutics, Inc.

(NASDAQ:MAZE)

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Neutral 52 (OpenAI - 5.2)
Rating:52Neutral
Price Target:
$27.00
▼(-2.46% Downside)
Action:Reiterated
Date:07/07/26
The score is held back primarily by weak financial performance (large TTM losses and substantial ongoing cash burn) and limited valuation support due to negative earnings and no dividend. Offsetting factors include a healthier balance sheet/leverage profile and a positive corporate catalyst from the $150M financing that extends runway into 2029, while technicals are constructive short-term but appear overbought and still below longer-term moving averages.
Positive Factors
Low Leverage / Strong Equity Cushion
Low debt relative to equity and a sizable equity cushion give Maze durable financial flexibility to fund R&D and absorb setbacks. For an early-stage biotech this reduces refinancing pressure and supports multi-year development programs without immediate leverage risk.
Negative Factors
Large, Persistent Cash Burn
Sustained negative operating and free cash flow indicate heavy burn tied to development activities. Persistent cash outflows force reliance on external financing, compress strategic optionality and increase execution risk if clinical progress or financing windows deteriorate.
Read all positive and negative factors
Positive Factors
Negative Factors
Low Leverage / Strong Equity Cushion
Low debt relative to equity and a sizable equity cushion give Maze durable financial flexibility to fund R&D and absorb setbacks. For an early-stage biotech this reduces refinancing pressure and supports multi-year development programs without immediate leverage risk.
Read all positive factors

Maze Therapeutics, Inc. (MAZE) vs. SPDR S&P 500 ETF (SPY)

Maze Therapeutics, Inc. Business Overview & Revenue Model

Company Description
Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney and metabolic diseases in the United States. Its lead programs include MZE829, an oral small molecule inhi...
How the Company Makes Money
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Maze Therapeutics, Inc. Financial Statement Overview

Summary
Overall fundamentals are weak and volatile: TTM shows $20.0M revenue but a large net loss (-$122.5M) and deeply negative operating profit, alongside heavy cash burn (TTM operating cash flow -$121.5M; free cash flow -$122.1M). The balance sheet is a relative bright spot with low leverage (debt-to-equity ~0.07) and sizable equity ($341.7M), but profitability and cash generation are not yet durable.
Income Statement
28
Negative
Balance Sheet
62
Positive
Cash Flow
33
Negative
BreakdownTTMDec 2025Mar 2025Dec 2023Dec 2022
Income Statement
Total Revenue20.00M0.00167.50M0.000.00
Gross Profit18.41M-2.40M167.50M0.000.00
EBITDA-119.51M-128.72M56.70M-96.33M-111.12M
Net Income-122.54M-131.12M52.23M-100.42M-114.94M
Balance Sheet
Total Assets419.71M397.13M240.54M71.50M149.96M
Cash, Cash Equivalents and Short-Term Investments352.38M341.92M196.81M29.16M99.92M
Total Debt61.22M23.31M26.63M49.62M32.05M
Total Liabilities78.01M42.16M43.64M61.45M48.51M
Stockholders Equity341.70M354.97M196.90M10.05M101.44M
Cash Flow
Free Cash Flow-122.13M-112.73M74.81M-87.27M-101.17M
Operating Cash Flow-121.54M-111.94M75.95M-86.83M-99.20M
Investing Cash Flow-164.39M-170.96M-1.15M-441.00K-3.17M
Financing Cash Flow190.32M275.34M92.85M16.39M1.73M

Maze Therapeutics, Inc. Technical Analysis

Technical Analysis Sentiment
Positive
Last Price27.68
Price Trends
50DMA
27.53
Positive
100DMA
21.03
Positive
200DMA
Market Momentum
MACD
1.29
Positive
RSI
60.57
Neutral
STOCH
78.16
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MAZE, the sentiment is Positive. The current price of 27.68 is below the 20-day moving average (MA) of 31.15, above the 50-day MA of 27.53, and equal to the 200-day MA of ―, indicating a neutral trend. The MACD of 1.29 indicates Positive momentum. The RSI at 60.57 is Neutral, neither overbought nor oversold. The STOCH value of 78.16 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MAZE.

Maze Therapeutics, Inc. Risk Analysis

Maze Therapeutics, Inc. disclosed 83 risk factors in its most recent earnings report. Maze Therapeutics, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Maze Therapeutics, Inc. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$1.78B-0.23-122.61%-721.01%
55
Neutral
$528.48M-1.51-57.31%-40.48%39.96%
54
Neutral
$1.59B-2.50-54.32%11.07%32.35%
53
Neutral
$1.49B-3.02-57.27%45.04%32.42%
52
Neutral
$1.49B-9.79-36.63%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.79B-2.8138.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MAZE
Maze Therapeutics, Inc.
27.33
12.08
79.21%
NTLA
Intellia Therapeutics
10.77
-1.35
-11.14%
DMRA
Damora Therapeutics
28.56
25.18
744.97%
RXRX
Recursion Pharmaceuticals
3.18
-2.62
-45.17%
DNA
Ginkgo Bioworks Holdings
8.94
-4.66
-34.26%
GENB
Generate Biomedicines, Inc.
14.34
1.69
13.36%

Maze Therapeutics, Inc. Corporate Events

Executive/Board ChangesShareholder Meetings
Maze Therapeutics Shareholders Elect Directors, Ratify Auditor
Positive
Jun 10, 2026
On June 8, 2026, Maze Therapeutics, Inc. held its 2026 annual meeting of stockholders with 44,660,029 shares of common stock represented, or about 89.75% of shares entitled to vote, establishing a quorum for business. Stockholders voted on the ele...
Executive/Board Changes
Maze Therapeutics CFO Expands Role Amid Finance Leadership Change
Neutral
May 22, 2026
On May 18, 2026, Maze Therapeutics, Inc. announced that Senior Vice President of Finance Amy Bachrodt had submitted her resignation, effective June 1, 2026, noting that her departure did not stem from any disagreement over the company’s oper...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 07, 2026