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Geron Corp (GERN)
NASDAQ:GERN
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Geron (GERN) AI Stock Analysis

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GERN

Geron

(NASDAQ:GERN)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
$1.50
▼(-10.71% Downside)
Action:ReiteratedDate:05/09/26
The score is held down primarily by continued losses and meaningful cash burn despite improving revenue, plus bearish technical signals with the stock trading below major moving averages. The latest earnings call supports the outlook with reiterated 2026 guidance, solid growth, and cost discipline, but gross-to-net headwinds, cash decline, and upcoming clinical/regulatory uncertainties cap the overall rating.
Positive Factors
Strong revenue ramp and commercial adoption
Consistent double‑digit revenue growth and expanding prescriber penetration indicate durable product‑market fit. Sequential demand gains and rising account counts create a scalable commercial foundation that supports ongoing market development, predictable topline growth and reinvestment in sales and education over the next several quarters.
Negative Factors
Persistent cash burn and negative free cash flow
Sustained negative operating and free cash flow indicate the business is not yet self‑funding. Continued burn has already driven a quarter‑over‑quarter cash decline and, if persistent, will force external financing or major margin improvement, limiting strategic flexibility and potentially diluting shareholders over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong revenue ramp and commercial adoption
Consistent double‑digit revenue growth and expanding prescriber penetration indicate durable product‑market fit. Sequential demand gains and rising account counts create a scalable commercial foundation that supports ongoing market development, predictable topline growth and reinvestment in sales and education over the next several quarters.
Read all positive factors

Geron (GERN) vs. SPDR S&P 500 ETF (SPY)

Geron Business Overview & Revenue Model

Company Description
Geron Corporation, a late-stage clinical biopharmaceutical company, focuses on the development and commercialization of therapeutics for myeloid hematologic malignancies. It develops imetelstat, a telomerase inhibitor that is in Phase 3 clinical t...
How the Company Makes Money
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Geron Earnings Call Summary

Earnings Call Date:May 06, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Positive
The call conveyed a largely positive operational and commercial story: strong revenue growth (+31% YoY), expanding demand (+6% QoQ) and disciplined cost reductions position Geron to meet 2026 guidance. Important clinical and regulatory milestones (IMpactMF enrollment, NCCN order template inclusion, peer-reviewed publication) bolster the long-term value proposition. Key risks highlighted include widening gross-to-net pressure (21% vs 13% prior year), a meaningful quarter-over-quarter cash decline (~$60M) driven by one-time and supply investments, and unresolved European commercialization/pricing decisions. On balance, the favorable revenue trajectory, cost discipline and clinical progress outweigh the manageable near-term financial and market-access headwinds.
Positive Updates
Progress on ex-U.S. strategy and leadership additions
Active engagement with European medical experts, HTA work and pricing research underway with an intent to announce a commercialization approach for Europe before year-end; strengthened leadership with recruitment of a new Chief Legal Officer and two new board members.
Negative Updates
Widening gross-to-net reductions
Gross-to-net reductions rose to 21% for Q1 2026 versus 13% in Q1 2025 (driven by wider 340B utilization and expanded GPO contracting); management expects gross-to-net to remain in the low- to mid-20s for the remainder of 2026, creating pressure on realized net revenue.
Read all updates
Q1-2026 Updates
Negative
Progress on ex-U.S. strategy and leadership additions
Active engagement with European medical experts, HTA work and pricing research underway with an intent to announce a commercialization approach for Europe before year-end; strengthened leadership with recruitment of a new Chief Legal Officer and two new board members.
Read all positive updates
Company Guidance
Geron reiterated 2026 guidance calling for RYTELO net revenue of $220–$240 million and total operating expenses of $230–$240 million, while reporting Q1 2026 net revenue of $51.8 million (up 31% YoY and 8% QoQ, vs. $39.6M in Q1 2025); gross‑to‑net rose to 21% (from 13% a year ago) and is expected to be in the low‑to‑mid‑20s for the remainder of 2026. Q1 operating expenses excluding COGS were $50.4M (down ~9% YoY from $55.1M), with R&D of $15.0M (vs. $15.1M) and SG&A of $35.4M (vs. $40.0M). Cash and equivalents were approximately $341M at March 31, 2026 (versus $401M at Dec 31, 2025), reflecting annual bonuses, severance and CMC investments. Commercial KPIs included 6% QoQ demand growth, ~12% increase in prescribing accounts to ~1,450, and 33% of patient starts in the first/second‑line (rolling 12‑month); management expects a greater portion of 2026 growth in the back half of the year. IMpactMF interim analysis is projected in H2 2026 (final analysis planning H2 2028) and initial real‑world evidence is expected in H2 2026.

Geron Financial Statement Overview

Summary
Revenue is ramping sharply, but profitability remains weak (TTM net loss) and cash burn is significant (TTM operating/FCF about -$126M). The balance sheet is supportive near term with a sizable equity base and manageable leverage, but negative returns and ongoing burn keep overall financial strength below average.
Income Statement
35
Negative
Balance Sheet
58
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue196.12M183.88M76.99M237.00K596.00K1.39M
Gross Profit169.81M179.14M75.74M237.00K596.00K1.39M
EBITDA-40.69M-51.92M-154.85M-174.78M-134.15M-111.59M
Net Income-69.59M-85.78M-174.57M-184.13M-141.90M-116.11M
Balance Sheet
Total Assets534.12M570.54M593.78M394.08M190.57M226.03M
Cash, Cash Equivalents and Short-Term Investments314.29M359.80M406.57M333.70M172.75M183.72M
Total Debt251.84M251.57M121.72M85.90M55.75M55.00M
Total Liabilities305.01M344.67M313.46M146.13M110.58M99.62M
Stockholders Equity229.11M225.87M280.32M247.95M80.00M126.42M
Cash Flow
Free Cash Flow-126.30M-111.09M-219.30M-168.57M-127.81M-95.76M
Operating Cash Flow-125.96M-111.04M-218.62M-167.74M-127.38M-95.56M
Investing Cash Flow106.66M107.25M-106.00M-180.32M62.07M71.95M
Financing Cash Flow4.44M2.27M334.37M362.02M87.26M48.56M

Geron Technical Analysis

Technical Analysis Sentiment
Positive
Last Price1.68
Price Trends
50DMA
1.63
Positive
100DMA
1.48
Positive
200DMA
1.39
Positive
Market Momentum
MACD
0.04
Negative
RSI
52.79
Neutral
STOCH
25.73
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GERN, the sentiment is Positive. The current price of 1.68 is above the 20-day moving average (MA) of 1.62, above the 50-day MA of 1.63, and above the 200-day MA of 1.39, indicating a bullish trend. The MACD of 0.04 indicates Negative momentum. The RSI at 52.79 is Neutral, neither overbought nor oversold. The STOCH value of 25.73 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for GERN.

Geron Risk Analysis

Geron disclosed 67 risk factors in its most recent earnings report. Geron reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Geron Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
$621.15M16.3558.50%617.03%
61
Neutral
$2.02B4.531813.84%157.01%94.31%
58
Neutral
$1.37B-5.44-62.48%-86.21%
52
Neutral
$1.70B-4.79-145.81%-10.44%19.99%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$1.90B-11.85-256.66%397.28%27.68%
47
Neutral
$891.71M-68.46-28.90%68.64%50.57%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GERN
Geron
1.39
0.21
17.80%
CRMD
Cormedix
7.92
-3.74
-32.08%
QURE
uniQure
27.66
14.87
116.26%
SNDX
Syndax Pharmaceuticals
21.49
10.79
100.84%
ANAB
AnaptysBio
69.33
56.27
430.94%
AVBP
ArriVent BioPharma, Inc.
29.50
9.35
46.40%

Geron Corporate Events

Business Operations and StrategyExecutive/Board Changes
Geron Adds Seasoned Industry Leaders to Board of Directors
Positive
Mar 26, 2026
On March 25, 2026, Geron Corporation’s board elected industry veterans Patricia S. Andrews and Constantine Chinoporos as Class III directors, with terms running until the 2026 annual shareholders’ meeting, and appointed Andrews to the ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 09, 2026