Clinical Development MomentumInterim imetelstat study results remain on track and favorable subgroup survival trends point to a possible clinical and regulatory catalyst if those signals are confirmed in later data.
Commercial Traction And AdoptionExpanded commercial efforts have increased ordering accounts by hundreds and produced a high reordering rate, indicating rising physician familiarity that could support broader and earlier use of Rytelo.
Restructuring And Cost DisciplineRestructuring that reduces headcount by roughly one third and narrows operating expense guidance is intended to improve cost efficiency and move the company toward positive cash flow and potential profitability.