Clinical TrialsMaze's Phase 1 HV data from the MZE782 program showed a robust PD signal, reinforcing best-in-class potential of '782 in PKU.
Market PositionMZE829’s dual mechanism of action likely sets it apart from the current AMKD treatment landscape, potentially delaying disease progression and reversing patients out of disease.
Regulatory PathwayThe validation of proteinuria and slope as surrogate endpoints would de-risk Maze’s regulatory path and potentially shorten timelines to approval.