Nuvation Bio (NUVB) AI Stock Analysis

• Market Cap: $1.66B
• Dividend Yield: N/A
• Average Volume (3M): 8.12M
• Price to Earnings (P/E): ―
• Beta (1Y): 2.17
• Revenue Growth: 1137.19%
• EPS Growth: 70.51%
• Country: US
• Employees: 273
• Sector: Healthcare
• Sector Strength: 45
• Industry: Biotechnology
• EPS (TTM): -0.16
• Shares Outstanding: 342,833,440
• 10 Day Avg. Volume: 10,525,031
• 30 Day Avg. Volume: 8,124,505
• PEG Ratio: >-0.01
• Price to Book (P/B): 1.54
• Price to Sales (P/S): 90.81
• P/FCF Ratio: -5.48
• Enterprise Value/Market Cap: 0.56
• Enterprise Value/Revenue: 34.62
• Enterprise Value/Gross Profit: 63.80
• Enterprise Value/Ebitda: -4.30
• 1Y Price Target: $9.14
• Price Target Upside: 85.77% Upside
• Rating Consensus: Strong Buy
• Number of Analyst Covering: 8
• EPS Forecast (FY): N/A
• Revenue Forecast (FY): N/A

• Rating: 45 Neutral
• Price Target: ―

Nuvation Bio's stock is primarily challenged by weak financial performance, characterized by ongoing losses and negative cash flows, despite a strong equity foundation. While there is short-term momentum in the stock price, the lack of sustainable income and negative valuation metrics, such as a negative P/E ratio, weigh heavily on the overall score. The stock's speculative nature and reliance on future growth prospects contribute to its moderate overall score.

Positive Factors

Revenue Growth

Nuvation Bio's significant revenue growth reflects the potential success of its oncology drug pipeline, indicating strong market demand and the effectiveness of its therapeutic approaches. This growth can lead to increased market share and financial stability over time.

Low Leverage

A low leverage position provides Nuvation Bio with financial flexibility to invest in R&D and strategic initiatives without the burden of high-interest obligations, supporting long-term growth and resilience against market fluctuations.

Regulatory Approvals

Securing regulatory approvals for key drugs enhances Nuvation Bio's credibility and market access, potentially accelerating revenue generation and establishing a competitive edge in the oncology market.

Negative Factors

Negative Cash Flow

Persistent negative cash flow indicates challenges in generating sufficient cash from operations, which may necessitate reliance on external financing, potentially affecting the company's financial sustainability and investment capacity.

Profitability Challenges

Ongoing profitability issues highlight operational inefficiencies and the need for cost management improvements, which could impact Nuvation Bio's ability to reinvest in growth and innovation.

CEO Departure

The departure of a key executive, even after achieving goals, can lead to leadership gaps and strategic uncertainty, potentially affecting the company's operational continuity and strategic execution.

Nuvation Bio Business Overview & Revenue Model

Company Description

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutic candidates for oncology. The company's lead product candidate is NUV-422, a small molecule inhibitor targeting cyclin-dependent kinase (CDK)2, CDK4, and CDK6. It is also developing NUV-868, a selective oral small molecule BET inhibitor that epigenetically regulates proteins that control tumor growth and differentiation; NUV-569, a differentiated oral small molecule selective inhibitor of the Wee1 kinase for DNA damage repair; NUV-1182, an adenosine receptor inhibitor; and drug-drug conjugate (DDC) platform that focuses on targeting an inhibitor of poly ADP ribose polymerase (PARP) to anti-cancer warheads of existing drugs, as well as PARP inhibitor to address ER+ breast and ovarian cancer. The company was formerly known as RePharmation Inc. and changed its name to Nuvation Bio Inc. in April 2019. Nuvation Bio Inc. was founded in 2018 and is headquartered in New York, New York.

How the Company Makes Money

Nuvation Bio makes money primarily through the development and commercialization of its pharmaceutical products. The company generates revenue from various streams, including partnerships with other biotech and pharmaceutical companies, licensing agreements, and potential future sales of its drug candidates once they receive regulatory approval. Significant partnerships with industry players or research institutions can also provide funding and collaborative opportunities, contributing to the company's financial growth. Additionally, Nuvation Bio may engage in strategic collaborations to enhance its research and development capabilities, which can also lead to milestone payments and royalties that serve as key revenue streams.

Nuvation Bio Financial Statement Overview

Summary

Nuvation Bio faces significant financial challenges, marked by consistent net losses and negative cash flows, despite a strong equity base and low leverage. The recent revenue increase is a positive sign, yet operational and cash flow improvements are necessary for long-term sustainability. The company's financial health is currently weak, primarily due to its inability to generate positive net income and operating cash flow.

Income Statement

Nuvation Bio has struggled with profitability, exhibiting a negative net profit margin due to substantial net losses over the years. Although there was a notable revenue increase in 2024, margins remain negative, highlighting ongoing operational challenges. The absence of revenue in prior years underscores the lack of stable income streams.

Balance Sheet

The company maintains a strong equity position with a debt-to-equity ratio that indicates low leverage, which is a positive aspect. However, the persistent negative net income has affected the return on equity, which is currently unfavorable. The equity ratio is high, showing that the company is mainly financed through equity, which can be advantageous in managing financial risk.

Cash Flow

Nuvation Bio's cash flow statement reveals a lack of positive operating cash flow, with free cash flow also being negative. This signifies potential issues in cash generation from operations. The company has been relying on financing activities to support cash needs, which may not be sustainable in the long term.

Breakdown	TTM	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020
Income Statement
Total Revenue	26.75M	7.87M	0.00	0.00	0.00	0.00
Gross Profit	14.51M	795.00K	-222.00K	-484.00K	-368.00K	-103.00K
EBITDA	-215.45M	-566.91M	-99.60M	-119.53M	-89.35M	-43.45M
Net Income	-217.48M	-567.94M	-75.80M	-104.20M	-86.85M	-41.66M
Balance Sheet
Total Assets	601.56M	540.63M	621.48M	672.14M	776.15M	221.79M
Cash, Cash Equivalents and Short-Term Investments	549.04M	502.69M	611.21M	661.01M	765.39M	215.75M
Total Debt	10.46M	8.91M	4.01M	4.26M	3.06M	0.00
Total Liabilities	275.68M	76.84M	16.36M	17.07M	30.15M	6.71M
Stockholders Equity	325.88M	463.79M	605.12M	655.08M	746.00M	215.08M
Cash Flow
Free Cash Flow	-94.65M	-130.57M	-68.07M	-96.48M	-68.47M	-36.67M
Operating Cash Flow	-94.48M	-130.41M	-68.00M	-96.11M	-68.19M	-36.53M
Investing Cash Flow	64.21M	122.70M	8.92M	63.46M	-454.67M	-70.32M
Financing Cash Flow	193.57M	331.00K	628.00K	1.33M	625.53M	133.13M

Nuvation Bio Technical Analysis

• Technical Analysis Sentiment: Positive
• Last Price: 4.92
• 50DMA: Positive
• 100DMA: Positive
• 200DMA: Positive
• MACD: Negative
• RSI: Neutral
• STOCH: Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NUVB, the sentiment is Positive. The current price of 4.92 is above the 20-day moving average (MA) of 4.39, above the 50-day MA of 3.76, and above the 200-day MA of 2.59, indicating a bullish trend. The MACD of 0.43 indicates Negative momentum. The RSI at 63.43 is Neutral, neither overbought nor oversold. The STOCH value of 64.62 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for NUVB.

Nuvation Bio Peers Comparison

Name	Overall Rating	Market Cap	P/E Ratio	ROE	Dividend Yield	Revenue Growth	EPS Growth
PRAX	58 Neutral	$4.15B	―	-60.98%	―	338.45%	-19.64%
PGEN	52 Neutral	$1.16B	―	-668.03%	―	-1.12%	20.77%
Sector *	51 Neutral	$7.86B	-0.30	-43.30%	2.27%	22.53%	-2.21%
WVE	49 Neutral	$1.27B	―	-171.41%	―	-14.98%	-51.76%
NKTR	47 Neutral	$1.07B	―	-440.80%	―	-19.56%	35.55%
NUVB	45 Neutral	$1.66B	―	-52.49%	―	1137.19%	70.51%
ELVN	36 Underperform	$1.13B	-9.50	-25.26%	―	―	-3.53%

Nuvation Bio Corporate Events

Nuvation Bio CEO Departs After Achieving Key Goals

On February 12, 2025, Dr. Jerry Wang, CEO of AnHeart Therapeutics, a subsidiary of Nuvation Bio Inc., departed the company after achieving key goals, including regulatory approvals for taletrectinib in China and the U.S., and the integration of AnHeart Therapeutics post-merger. Dr. Wang’s departure was not due to any disagreements, and his role as CEO was deemed unnecessary following these accomplishments.