Education
About Us
Working with TipRanks
Follow Us
XBI - ETF AI Analysis
Top Page
SPDR S&P BIOTECH ETF (XBI)
Rating:60Neutral
Price Target:
$119.00
Positive Factors
Strong Year-to-Date Performance
The ETF has delivered solid gains so far this year, indicating positive momentum in the biotech sector.
Low Expense Ratio
The fund charges a relatively low fee, making it cost-effective for investors compared to many other ETFs.
Top Holdings Showing Strength
Several of the largest positions, such as Ionis Pharmaceuticals and Insmed, have shown strong year-to-date performance.
Negative Factors
Sector Over-Concentration
The ETF is heavily focused on the healthcare sector, which limits diversification and increases exposure to industry-specific risks.
Geographic Concentration
With nearly all assets invested in U.S. companies, the fund lacks global diversification and is vulnerable to domestic market fluctuations.
Mixed Performance Among Top Holdings
Some key holdings, such as Vertex Pharmaceuticals and Exact Sciences, have shown weaker year-to-date performance, which could drag on overall returns.
XBI vs. SPDR S&P 500 ETF (SPY)
AUM7.37B
RegionNorth America
Expense Ratio0.35%
Beta1.00
IssuerSPDR
Inception DateJan 31, 2006
Dividend Yield0.04%
Asset ClassEquity
Index TrackedS&P Biotechnology Select Industry
Share Statistics
EPS (TTM)N/A
Shares OutstandingN/A
10 Day Avg. Volume12,489,600
30 Day Avg. Volume10,366,472
Financial Highlights & Ratios
PEG RatioN/A
Price to Book (P/B)N/A
Price to Sales (P/S)N/A
P/FCF RatioN/A
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price Target
156.39Price Target Upside― Downside
Rating ConsensusModerate Buy
Number of Analyst Covering128
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
XBI Summary
The SPDR S&P Biotech ETF (XBI) is a fund that focuses on the biotechnology sector, part of the health care industry. It includes a mix of companies, from established names like Amgen and Vertex Pharmaceuticals to smaller, innovative firms working on cutting-edge medical advancements like gene editing and personalized medicine. This ETF offers a way to invest in the growth potential of biotech, a field known for driving transformative health care solutions. However, new investors should be aware that the biotech sector can be volatile, as stock prices often depend on the success of clinical trials and regulatory approvals.
How much will it cost me?The SPDR S&P Biotech ETF (XBI) has an expense ratio of 0.35%, meaning you’ll pay $3.50 per year for every $1,000 invested. This expense ratio is slightly higher than average because the fund is actively managed with an equal-weighted structure, which requires more frequent adjustments compared to passively managed ETFs.
What would affect this ETF?The SPDR S&P Biotech ETF (XBI) could benefit from advancements in biotechnology, such as breakthroughs in gene editing and personalized medicine, which drive innovation and growth in the sector. However, it may face challenges from regulatory hurdles, high research costs, and potential economic downturns that could impact funding and investor sentiment in the biotech industry.
XBI Top 10 Holdings
The SPDR S&P Biotech ETF (XBI) is a bet on innovation, with its equal-weighted structure spreading exposure across established players like Regeneron and Amgen, as well as rising stars like Avidity Biosciences and BridgeBio Pharma. Regeneron’s steady performance and robust R&D investments provide stability, while Avidity and BridgeBio are riding bullish momentum despite financial hurdles typical of smaller biotech firms. The fund’s heavy concentration in U.S.-based health care companies underscores its focus on cutting-edge medical breakthroughs, though profitability challenges across the sector may hold back broader gains.
Name | Company Name | Weight % | Market Value | Market Cap | Yearly Gain | Overall Rating |
|---|---|---|---|---|---|---|
| Exact Sciences | 3.00% | $219.08M | $19.12B | 90.70% | 62 Neutral | |
| Revolution Medicines | 2.55% | $186.08M | $13.70B | 24.88% | 52 Neutral | |
| Avidity Biosciences | 2.49% | $181.48M | $10.63B | 63.14% | 56 Neutral | |
| Insmed | 2.23% | $163.06M | $42.39B | 171.72% | 53 Neutral | |
| Natera | 2.17% | $158.34M | $31.83B | 37.89% | 68 Neutral | |
| Regeneron | 2.16% | $158.04M | $79.44B | 2.42% | 81 Outperform | |
| Madrigal Pharmaceuticals | 2.06% | $150.22M | $12.44B | 57.71% | 56 Neutral | |
| BridgeBio Pharma | 1.99% | $145.43M | $13.13B | 190.82% | 55 Neutral | |
| Amgen | 1.97% | $143.83M | $181.76B | 14.60% | 77 Outperform | |
| United Therapeutics | 1.96% | $142.71M | $20.44B | 27.34% | 79 Outperform |
XBI Technical Analysis
Positive
―
Price Trends
106.22
Positive
97.48
Positive
90.14
Positive
Market Momentum
2.53
Negative
67.45
Neutral
73.62
Neutral
Evaluating momentum and price trends is crucial in ETF analysis to make informed investment decisions. For XBI, the sentiment is Positive. The current price of undefined is equal to the 20-day moving average (MA) of 112.18, equal to the 50-day MA of 106.22, and equal to the 200-day MA of 90.14, indicating a bullish trend. The MACD of 2.53 indicates Negative momentum. The RSI at 67.45 is Neutral, neither overbought nor oversold. The STOCH value of 73.62 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for XBI.
XBI Peer Comparison
Comparison Results
Performance Comparison
XBI
SPDR S&P BIOTECH ETF
116.65
17.85
18.07%
IBB
iShares Biotechnology ETF
―
―
―
IHI
iShares U.S. Medical Devices ETF
―
―
―
IYH
iShares U.S. Healthcare ETF
―
―
―
FHLC
Fidelity MSCI Health Care Index ETF
―
―
―
FBT
First Trust NYSE Arca Biotechnology Index Fund
―
―
―
Glossary
BuyAn ETF rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF is likely to deliver higher returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldAn ETF rated as a "Hold" s expected to perform in line with the overall market or a specific benchmark. This rating indicates that the ETF is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellAn ETF rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the ETF may deliver lower returns compared to other ETFs in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst ETF Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in ETFs carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: ―
Table of Contents