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SPDR S&P BIOTECH ETF
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XBI Holdings Information

Compare
Holdings Count
128
Total Assets
7.37B
Top 10 Percentage
22.58%
Asset Class
Equity
Category
Sector
Region
North America
See the full list of holdings, find out what stocks are the most undervalued and get access to the all ETF's smart score and filters.Go Premium
128 Holdings as of Nov 21, 2025
128 Holdings as of Nov 21, 2025
Name
Weight %
Market Value
Price & Change
Market Cap
Yearly Gain
Analyst Consensus
Analyst Price Target
Smart Score
Follow
EXAS
Exact Sciences Corp
3.00%
$219.08M
―
$19.12B
82.99%
4 Buy
17 Hold
0 Sell
Hold
―
RVMD
Revolution Medicines, Inc.
2.55%
$186.08M
―
$13.70B
23.25%
20 Buy
0 Hold
0 Sell
Strong Buy
―
RNA
Avidity Biosciences Inc
2.49%
$181.48M
―
$10.63B
56.35%
5 Buy
10 Hold
0 Sell
Moderate Buy
―
INSM
Insmed
2.23%
$163.06M
―
$42.39B
168.27%
17 Buy
1 Hold
0 Sell
Strong Buy
―
NTRA
Natera Inc.
2.17%
$158.34M
―
$31.83B
37.89%
14 Buy
2 Hold
0 Sell
Strong Buy
―
REGN
Regeneron Pharmaceuticals
2.16%
$158.04M
―
$79.44B
0.85%
17 Buy
5 Hold
1 Sell
Moderate Buy
―
MDGL
Madrigal
2.06%
$150.22M
―
$12.44B
58.75%
11 Buy
1 Hold
0 Sell
Strong Buy
―
BBIO
Bridgebio Pharma
1.99%
$145.43M
―
$13.13B
150.50%
17 Buy
0 Hold
0 Sell
Strong Buy
―
AMGN
Amgen Inc
1.97%
$143.83M
―
$181.76B
14.60%
8 Buy
10 Hold
1 Sell
Moderate Buy
―
UTHR
United Therapeutics Corp.
1.95%
$142.71M
―
$20.44B
28.80%
9 Buy
4 Hold
0 Sell
Moderate Buy
―
Rows:
10

Sector Breakdown

99.23%Healthcare0.77%General99.23%Healthcare
Healthcare
99.23%
General
0.77%

Countries Breakdown

100.00%United States100.00%United States
United States
100.00%

Breakdown By Smart Score

19.65%Outperform1013.21%Outperform915.20%Outperform819.08%Neutral79.70%Neutral66.99%Neutral57.91%Neutral43.18%Underperform32.61%Underperform22.47%Underperform17
The weighted average smart score of the XBI ETF is 7
10
19.65%
9
13.21%
8
15.20%
7
19.08%
6
9.70%
5
6.99%
4
7.91%
3
3.18%
2
2.61%
1
2.47%

XBI ETF News

Unusually active option classes on open September 2nd
PremiumThe Fly

Unusually active option classes on open September 2nd

3M ago
AG
KR
Unusually active option classes on open July 9th
PremiumThe Fly

Unusually active option classes on open July 9th

5M ago
AES
CAT
Unusually active option classes on open May 9th
PremiumThe Fly

Unusually active option classes on open May 9th

7M ago
ELF
PAA
Controversial doctor Vinay Prasad named CBER director, STAT reports
PremiumThe Fly

Controversial doctor Vinay Prasad named CBER director, STAT reports

7M ago
DYN
RNA
See More XBI News
See More XBI News

XBI ETF FAQ

What are ETF XBI’s top 3 holdings?
XBI’s top 3 holdings are EXAS, RVMD, RNA.
    What is ETF XBI’s holdings count?
    ETF XBI’s is holdings 128 different assets.
      What are the total assets of ETF XBI?
      ETF XBI’s total assets are 7.37B.
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