tiprankstipranks
Trending News
More News >
GeneDx Holdings (WGS)
NASDAQ:WGS
US Market

GeneDx Holdings (WGS) AI Stock Analysis

Compare
750 Followers

Top Page

WG

GeneDx Holdings

(NASDAQ:WGS)

Rating:65Neutral
Price Target:
$98.00
▲(7.57%Upside)
GeneDx Holdings benefits from strong revenue growth and strategic advancements, as seen in the earnings call. However, ongoing profitability challenges and high P/E ratio concerns weigh on the score.
Positive Factors
Competitive Advantage
The company has a notable competitive advantage due to its extensive genotypic and phenotypic data, driving enhanced diagnostic yields.
Financial Performance
March rebounded strongly and exceeded management expectations, with April tracking in line with expectations and a seasonally stronger Q2 anticipated.
Market Opportunity
New guidelines from the AAP now recommend exome/genome as a first-line test for kids with development delay & intellectual disability, opening a big opportunity for WGS to access general pediatricians.
Negative Factors
Competitive Threats
Growing competitive threats are challenging GeneDx's market position, despite claims of a strong moat based on their database and diagnostic yields.
Insider Activity
Recent insider selling by the CEO and CFO has raised concerns about the optics of selling during a period of poor performance.
Internal Challenges
Investors are concerned about a lack of clarity on internal volume expectations and the timing or cause of the first quarter miss.

GeneDx Holdings (WGS) vs. SPDR S&P 500 ETF (SPY)

GeneDx Holdings Business Overview & Revenue Model

Company DescriptionGeneDx Holdings (WGS) is a pioneering company in the field of genomics, focused on providing advanced genetic testing and analysis. Operating primarily within the biotechnology and healthcare sectors, GeneDx offers comprehensive genomic services that include whole genome sequencing, exome sequencing, and specialized genetic testing solutions. The company's services are aimed at healthcare providers, researchers, and patients seeking to understand genetic conditions, with the goal of enabling personalized medicine and better clinical outcomes.
How the Company Makes MoneyGeneDx Holdings generates revenue through a diversified model primarily centered around its genetic testing services. The company charges fees for its sequencing services, which are utilized by hospitals, clinics, and research institutions. Its revenue streams include payments from healthcare providers who order genetic tests for their patients, as well as research collaborations with pharmaceutical companies and academic institutions. Additionally, GeneDx may receive funding from partnerships aimed at developing new genomic technologies and solutions. The company benefits from the growing demand for precision medicine, which drives the need for accurate and comprehensive genetic testing, further contributing to its financial performance.

GeneDx Holdings Earnings Call Summary

Earnings Call Date:Apr 30, 2025
(Q1-2025)
|
% Change Since: -22.12%|
Next Earnings Date:Aug 18, 2025
Earnings Call Sentiment Positive
The earnings call highlighted strong revenue growth, profitability, and strategic advancements like the Fabric Genomics acquisition. However, challenges such as weather impacts on volumes and increased G&A expenses were noted. The company's positive momentum and strategic initiatives outweigh these challenges.
Q1-2025 Updates
Positive Updates
Strong First Quarter Revenue and Profitability
GeneDx reported first-quarter revenues exceeding $87 million and achieved its third consecutive quarter of profitability. Exome and genome revenues grew 62% year-over-year.
Raising Full-Year Revenue Guidance
The company raised its full-year 2025 revenue guidance to $360 million to $375 million, reflecting confidence in continued momentum and market leadership.
Significant Growth in Exome and Genome Testing
Volumes from flagship products increased by 24% year-over-year, contributing $71.4 million in revenue. The company expects at least 30% growth in exome genome volume and revenues for full year 2025.
Successful Launch of Ultra Rapid Genome Sequencing
GeneDx launched an ultra rapid genome sequencing product with a 48-hour turnaround time, enhancing its service offering in the NICU.
Positive Reimbursement Trends
Average reimbursement rate for exome and genome tests increased to approximately $3,400, up from $2,600 in the same quarter last year.
Strategic Acquisition of Fabric Genomics
GeneDx announced plans to acquire Fabric Genomics to enhance its AI-powered genomic interpretation capabilities and expand into international markets.
Negative Updates
Weather Impact on Test Volumes
Adverse weather conditions in January and February affected test volumes, resulting in a sequential decline in volumes from Q4 to Q1.
Challenges in Expanding NICU Market
Despite the launch of the ultra rapid genome sequencing product, the NICU market remains untapped with less than 5% of babies receiving genetic tests.
Increase in G&A Expenses
General and administrative expenses increased, partly due to Epic integration costs and general support costs for the company's growth.
Company Guidance
During the GeneDx First Quarter 2025 Earnings Conference Call, the company shared several key metrics and updates. GeneDx reported first-quarter revenues of $87.1 million, with exome and genome revenues growing 62% year-over-year to $71.4 million. The company raised its full-year 2025 revenue guidance to between $360 million and $375 million, reflecting strong momentum, particularly in exome and genome testing, which accounted for 40% of all tests conducted in the quarter. GeneDx also highlighted its strategic acquisition of Fabric Genomics, which is expected to contribute $3 million to $5 million in revenue and expand the company's capabilities in AI-powered genomic interpretation. The average reimbursement rate for exome and genome testing rose to approximately $3,400 from $2,600 in the previous year, driven by reduced denials and positive beats on past estimates. The company maintained a strong gross margin of 69%, up from 61% a year ago, and achieved its third consecutive quarter of profitability with an adjusted net income of $7.7 million. GeneDx emphasized its ongoing efforts to expand into new clinical indications and its commitment to driving better clinical outcomes while reducing healthcare costs.

GeneDx Holdings Financial Statement Overview

Summary
GeneDx Holdings shows revenue growth and solid balance sheet metrics, but profitability issues persist with negative cash flow and net income margins.
Income Statement
55
Neutral
GeneDx Holdings has shown a positive revenue growth trend, with a TTM revenue increase to $330.1 million compared to $305.5 million in the previous year. Despite this growth, the company remains unprofitable, as evidenced by negative EBIT and net income margins. The gross profit margin improved to 63.9% TTM, signaling better cost management. However, persistent net losses and negative EBIT margins indicate ongoing operational challenges.
Balance Sheet
60
Neutral
The balance sheet shows a stable equity position with stockholders' equity at $257.4 million. The debt-to-equity ratio improved to 0.24 TTM, reflecting a manageable leverage level. Moreover, the equity ratio of 57.7% indicates a strong capital structure. However, the company has struggled with profitability, as seen from the negative return on equity, which poses a risk to financial stability if losses continue.
Cash Flow
50
Neutral
GeneDx Holdings reports negative free cash flow and operating cash flow, reflecting cash management challenges. Despite a significant improvement in free cash flow growth from the previous year, the company still faces hurdles in generating positive cash flow. The operating cash flow to net income ratio improved slightly TTM, yet remains negative, underscoring ongoing operational inefficiencies.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue330.14M305.45M202.57M234.69M212.19M179.32M
Gross Profit211.05M194.40M60.62M-26.75M-16.60M4.03M
EBITDA-20.55M-23.21M-136.46M-398.20M-219.19M-224.73M
Net Income-38.58M-52.29M-175.77M-548.98M-245.39M-246.44M
Balance Sheet
Total Assets446.43M419.38M473.67M490.94M554.09M251.64M
Cash, Cash Equivalents and Short-Term Investments159.16M141.19M130.15M123.93M400.57M108.13M
Total Debt114.84M116.17M119.77M72.38M32.85M45.02M
Total Liabilities189.03M174.13M245.66M237.24M165.99M581.69M
Stockholders Equity257.40M245.25M228.02M253.71M388.10M-330.05M
Cash Flow
Free Cash Flow-13.08M-33.99M-185.86M-333.48M-211.22M-125.10M
Operating Cash Flow-1.90M-28.50M-180.15M-319.15M-190.43M-93.13M
Investing Cash Flow-40.38M-30.13M-43.73M-141.33M-20.79M-31.97M
Financing Cash Flow58.32M44.16M186.24M197.31M493.73M129.06M

GeneDx Holdings Technical Analysis

Technical Analysis Sentiment
Positive
Last Price91.10
Price Trends
50DMA
75.57
Positive
100DMA
83.42
Positive
200DMA
75.45
Positive
Market Momentum
MACD
4.53
Negative
RSI
68.94
Neutral
STOCH
85.49
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For WGS, the sentiment is Positive. The current price of 91.1 is above the 20-day moving average (MA) of 74.93, above the 50-day MA of 75.57, and above the 200-day MA of 75.45, indicating a bullish trend. The MACD of 4.53 indicates Negative momentum. The RSI at 68.94 is Neutral, neither overbought nor oversold. The STOCH value of 85.49 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for WGS.

GeneDx Holdings Risk Analysis

GeneDx Holdings disclosed 74 risk factors in its most recent earnings report. GeneDx Holdings reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

GeneDx Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$1.88B38.8310.11%9.47%-7.81%
68
Neutral
$1.75B67.034.43%4.35%
WGWGS
65
Neutral
$2.60B38.75-16.61%48.81%72.54%
59
Neutral
$1.51B-43.33%22.29%-32.89%
DHDH
57
Neutral
$557.55M-86.36%-3.04%-152.59%
56
Neutral
$206.51M-60.75%4.66%11.33%
51
Neutral
$7.44B0.40-61.90%2.33%17.14%1.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
WGS
GeneDx Holdings
92.31
64.55
232.53%
PGNY
Progyny
22.00
-6.33
-22.34%
SDGR
Schrodinger
20.12
-0.21
-1.03%
GDRX
GoodRx Holdings
4.98
-2.84
-36.32%
SOPH
SOPHiA GENETICS
3.10
-1.49
-32.46%
DH
Definitive Healthcare Corp
3.90
-1.53
-28.18%

GeneDx Holdings Corporate Events

Executive/Board ChangesShareholder Meetings
GeneDx Holdings Approves Key Proposals at Annual Meeting
Neutral
Jun 18, 2025

On June 18, 2025, GeneDx Holdings Corp. held its Annual Meeting of Stockholders, where key proposals were voted on and approved. The stockholders elected two Class I directors, Eli D. Casdin and Joshua Ruch, to serve three-year terms, and ratified the appointment of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025.

The most recent analyst rating on (WGS) stock is a Buy with a $43.00 price target. To see the full list of analyst forecasts on GeneDx Holdings stock, see the WGS Stock Forecast page.

M&A TransactionsBusiness Operations and Strategy
GeneDx Holdings Acquires Fabric Genomics for $33 Million
Positive
Apr 16, 2025

On April 15, 2025, GeneDx Holdings Corp. announced an agreement to acquire Fabric Genomics for approximately $33 million, with potential additional payments based on future performance milestones. This acquisition aims to enhance GeneDx’s capabilities in decentralized genomic testing and AI-powered interpretation, expanding its market reach and improving the speed and accuracy of genetic disorder diagnoses. The merger is expected to close in the second quarter of 2025, subject to closing conditions, and will allow GeneDx to leverage Fabric Genomics’ AI platform to provide more scalable and impactful genomic interpretation services globally.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 25, 2025