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Valneva (VALN)
NASDAQ:VALN

Valneva (VALN) AI Stock Analysis

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VALN

Valneva

(NASDAQ:VALN)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$10.50
▲(4.58% Upside)
Valneva's overall stock score reflects significant financial challenges, including negative profitability and cash flow issues. While technical indicators show neutral momentum, and the earnings call highlighted some positive developments, the company's high leverage and ongoing losses weigh heavily on the score. Promising clinical advancements provide potential for future growth but are not enough to offset current financial concerns.
Positive Factors
Revenue Growth
The consistent revenue growth indicates Valneva's expanding market presence and successful product adoption, supporting long-term business stability.
Debt Refinancing
Refinancing improves financial flexibility, allowing Valneva to focus on strategic initiatives and reduce financial risk, supporting sustainable growth.
Lyme Disease Vaccine Development
Advancing Lyme disease vaccine development positions Valneva to capture market share in an unmet medical need, driving future revenue growth.
Negative Factors
High Leverage
High leverage poses financial risks and limits flexibility, potentially impacting Valneva's ability to invest in growth and manage economic downturns.
Negative Profitability
Sustained negative profitability indicates challenges in cost management and revenue generation, threatening long-term financial health and growth potential.
Cash Flow Challenges
Negative cash flow highlights operational inefficiencies and could hinder Valneva's ability to fund R&D and strategic initiatives, affecting future growth.

Valneva (VALN) vs. SPDR S&P 500 ETF (SPY)

Valneva Business Overview & Revenue Model

Company DescriptionValneva SE, a specialty vaccine company, focuses on the development and commercialization of prophylactic vaccines for infectious diseases with unmet needs. Its commercial vaccines for travelers include IXIARO, an inactivated Vero cell culture-derived Japanese encephalitis vaccine indicated for active immunization against Japanese encephalitis; DUKORAL, an oral vaccine for the prevention of diarrhea caused by Vibrio cholera and/or heat-labile toxin producing Enterotoxigenic Escherichia coli bacterium; and VLA2001, a vaccine candidate against SARS-CoV-2. The company also develops VLA15, a vaccine candidate that has completed Phase II clinical trial against Borrelia; and VLA1553, a vaccine candidate, which is in Phase III clinical trial against the chikungunya virus. It sells its products in the United States, Canada, Germany, Austria, Nordics, the United Kingdom, other European countries, and internationally. Valneva SE has collaborations with Pfizer, Inc. to co-develop and commercialize its Lyme disease vaccine; and Instituto Butantan for the development, manufacturing, and marketing of single-shot chikungunya vaccine. The company was founded in 1998 and is headquartered in Saint-Herblain, France.
How the Company Makes MoneyValneva generates revenue primarily through the development and commercialization of its vaccine products. The company's revenue streams include sales from licensed vaccines, government contracts, and partnerships with other pharmaceutical companies for research and development. Valneva has entered into significant collaborations, such as its partnership with the British government for the development of its COVID-19 vaccine, which provides funding and potential revenue from future vaccine sales. Additionally, Valneva may receive milestone payments and royalties from its collaborations, further contributing to its earnings. The company also seeks to expand its market presence through strategic partnerships that enhance its product pipeline and distribution capabilities.

Valneva Earnings Call Summary

Earnings Call Date:Nov 20, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Neutral
The company showed positive developments in revenue growth and cash management, along with promising clinical advancements. However, challenges remain with IXCHIQ sales suspension, DUKORAL sales decline, and operating losses.
Q3-2025 Updates
Positive Updates
Revenue Growth
Total revenues reached EUR 127 million, marking a growth of almost 9% despite geopolitical and IXCHIQ-specific challenges.
Operating Cash Burn Reduction
Significant reduction in operating cash burn, resulting in a cash position of more than EUR 140 million.
Debt Refinancing Success
Successfully completed debt refinancing, enhancing financial flexibility with Pharmakon as a new partner.
IXIARO Sales Increase
IXIARO sales reached EUR 74.3 million, a 12.5% increase driven by sales to the U.S. Department of Defense and increased sales in Europe.
Positive Clinical Data
Reported positive safety and immunogenicity data for the Lyme vaccine candidate and positive Phase I results for the Zika vaccine candidate.
Negative Updates
IXCHIQ Sales Impact
IXCHIQ sales were significantly impacted due to the temporary restriction and U.S. license suspension, leading to an adjustment of sales guidance.
DUKORAL Sales Decline
DUKORAL sales decreased from EUR 22.3 million to EUR 21.5 million, impacted by foreign currency fluctuations and transition to a new distributor in Germany.
Third-Party Product Sales Decrease
Third-party products sales decreased by 28.5% year-over-year to EUR 16.1 million due to the anticipated discontinuation of certain distribution agreements.
Operating Loss
Reported an operating loss of EUR 53.9 million compared to a profit last year, impacted by the absence of the prior year's Priority Review Voucher sale.
Company Guidance
In the recent conference call, Valneva provided guidance on its financial performance and strategic direction for the remainder of 2025 and beyond. The company reported total revenues of EUR 127 million for the first nine months of 2025, marking an increase of nearly 9% from the previous year, despite geopolitical and product-specific challenges. Product sales reached EUR 119.4 million, with IXIARO sales growing 12.5% to EUR 74.3 million, driven by demand from the U.S. Department of Defense and European markets. However, DUKORAL sales slightly decreased to EUR 21.5 million, impacted by currency fluctuations and a distributor transition in Germany. IXCHIQ sales saw a notable increase to EUR 7.6 million, despite a temporary U.S. license suspension affecting travel segment sales. Valneva's cash reserves stood at EUR 143.5 million as of September 30, 2025, bolstered by EUR 26 million from ATM transactions. The company maintained its full-year guidance, projecting product sales between EUR 155 million and EUR 170 million, and total revenues ranging from EUR 165 million to EUR 180 million. Looking ahead, Valneva emphasized the significant potential of its Lyme disease vaccine, VLA15, which is on track for regulatory submissions in 2026 and anticipated market launch in late 2027, positioning it as a key growth driver for sustained profitability.

Valneva Financial Statement Overview

Summary
Valneva's financial statements reflect challenges with profitability and cash flow. Despite a healthy gross profit margin, the company faces high leverage and negative profitability metrics. Revenue growth is modest, but operational efficiency and debt management need improvement.
Income Statement
45
Neutral
Valneva's income statement shows a mixed performance. The TTM gross profit margin is relatively healthy at 46.56%, indicating efficient cost management. However, the net profit margin is negative at -43.21%, reflecting ongoing losses. Revenue growth is modest at 5.52% TTM, but the company has struggled with profitability, as evidenced by negative EBIT and EBITDA margins. The company needs to focus on improving operational efficiency and profitability.
Balance Sheet
40
Negative
The balance sheet reveals a high debt-to-equity ratio of 1.20 TTM, indicating significant leverage, which could pose financial risks. The return on equity is negative, suggesting that the company is not generating sufficient returns on shareholders' equity. The equity ratio is moderate, but the company needs to manage its debt levels to improve financial stability.
Cash Flow
38
Negative
Cash flow analysis shows challenges, with negative operating cash flow and free cash flow TTM. The free cash flow growth rate is negative, indicating declining cash generation. The operating cash flow to net income ratio is also negative, highlighting cash flow issues. The company must enhance cash flow management to support its operations and growth.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue196.33M169.58M153.71M361.30M348.08M110.32M
Gross Profit96.25M71.04M52.84M36.86M160.16M56.02M
EBITDA-40.98M32.08M-57.72M-104.72M-38.73M-44.76M
Net Income-67.04M-12.25M-101.43M-143.28M-73.42M-64.39M
Balance Sheet
Total Assets472.63M500.03M460.06M621.34M817.35M449.16M
Cash, Cash Equivalents and Short-Term Investments161.31M168.27M126.08M289.43M346.64M204.39M
Total Debt196.92M216.31M208.82M152.38M114.66M105.45M
Total Liabilities286.19M318.78M331.81M401.55M646.77M371.74M
Stockholders Equity186.43M181.25M128.25M219.80M170.58M77.42M
Cash Flow
Free Cash Flow-34.39M-83.66M-217.06M-274.67M-16.27M118.27M
Operating Cash Flow-11.90M-67.22M-202.74M-245.34M76.90M137.74M
Investing Cash Flow-12.33M76.92M-20.59M-29.05M-93.12M-19.34M
Financing Cash Flow56.57M30.68M63.08M215.12M154.50M21.74M

Valneva Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.04
Price Trends
50DMA
8.93
Positive
100DMA
9.39
Positive
200DMA
8.14
Positive
Market Momentum
MACD
0.35
Negative
RSI
69.17
Neutral
STOCH
91.77
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For VALN, the sentiment is Positive. The current price of 10.04 is above the 20-day moving average (MA) of 8.99, above the 50-day MA of 8.93, and above the 200-day MA of 8.14, indicating a bullish trend. The MACD of 0.35 indicates Negative momentum. The RSI at 69.17 is Neutral, neither overbought nor oversold. The STOCH value of 91.77 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for VALN.

Valneva Risk Analysis

Valneva disclosed 86 risk factors in its most recent earnings report. Valneva reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Valneva Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$1.38B-14.22-64.93%-36.36%-945.72%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$1.26B-4.88-96.11%31.16%
50
Neutral
$877.20M-5.418.00%-10.15%
49
Neutral
$919.31M-21.55-45.88%116.64%47.93%
48
Neutral
$887.72M-7.56-54.42%14.86%-1440.45%
47
Neutral
$1.13B-1.47-12.52%-82.84%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
VALN
Valneva
10.37
6.06
140.60%
ABUS
Arbutus Biopharma
4.78
1.50
45.73%
URGN
Urogen Pharma
18.74
8.35
80.37%
IVA
Inventiva
5.98
3.82
176.85%
TSHA
Taysha Gene Therapies
5.04
3.41
209.20%
SANA
Sana Biotechnology
4.74
0.88
22.80%

Valneva Corporate Events

Valneva to Engage Investors at J.P. Morgan Conference Ahead of Key Lyme Vaccine Data
Jan 9, 2026

On January 9, 2026, Valneva announced that its management team, including CEO Thomas Lingelbach and CFO Peter Bühler, will hold one-on-one meetings with existing shareholders and other institutional specialist investors during the 44th Annual J.P. Morgan Healthcare Conference, taking place January 12–14, 2026, in San Francisco. The executives plan to discuss upcoming catalysts from Valneva’s clinical pipeline—most notably a pivotal data readout for its Lyme disease vaccine expected in the first half of 2026—alongside the performance of its commercial vaccine portfolio, signaling an effort to strengthen investor engagement and highlight the company’s late-stage assets and growth prospects.

The most recent analyst rating on (VALN) stock is a Hold with a $9.50 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Valneva Regains Full Rights to Chikungunya Vaccine as Serum Institute License Ends
Dec 31, 2025

On December 31, 2025, Valneva SE and Serum Institute of India announced they had mutually agreed to discontinue their license agreement covering Valneva’s single-shot chikungunya vaccine. By regaining full rights to the product, Valneva aims to take direct control of supply and commercialization in endemic high-risk countries, a shift intended to accelerate access in regions most affected by chikungunya and to align with its July 2024 funding agreement with CEPI, co-funded by the European Union, to support vaccine access in low- and middle-income countries. The move underscores Valneva’s strategy to tighten control over key assets in its portfolio and could strengthen its positioning in the growing market for vaccines against climate-sensitive vector-borne diseases, as chikungunya is spreading across more than 110 countries and is recognized by the WHO as a major public health problem.

The most recent analyst rating on (VALN) stock is a Hold with a $9.50 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Valneva Reports Positive Phase 2 Results for Chikungunya Vaccine in Children
Dec 11, 2025

Valneva SE announced positive final results from its Phase 2 clinical trial for the chikungunya vaccine IXCHIQ® in children aged one to eleven years. The trial demonstrated that the vaccine was well tolerated and maintained high antibody levels twelve months post-vaccination, supporting the selection of a full dose for future Phase 3 trials. The strong immune response and favorable safety profile observed in children align with previous findings in adolescents and adults. The company plans to gather additional real-world data in adolescents before proceeding with Phase 3 trials in children, highlighting the importance of a long-term protective vaccine for chikungunya, especially in regions with limited vaccine access.

The most recent analyst rating on (VALN) stock is a Hold with a $9.50 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Valneva Announces Strategic Consolidation of French Operations
Nov 28, 2025

On November 26, 2025, Valneva SE announced a strategic initiative to consolidate its operations in France, focusing its activities at the Lyon site and closing its Nantes location to streamline operations and improve efficiency. This move is part of Valneva’s efforts to enhance operational effectiveness and position itself for long-term success. The consolidation will also centralize all R&D activities in Vienna. The company is committed to supporting its employees during this transition, ensuring a smooth process for all affected team members.

The most recent analyst rating on (VALN) stock is a Hold with a $9.50 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Valneva Reports Nine-Month 2025 Financial Results and Updates on Vaccine Developments
Nov 26, 2025

On November 26, 2025, Valneva SE announced its financial results for the first nine months of 2025, reporting total revenues of €127.0 million, an 8.9% increase from the previous year. Despite a net loss of €65.2 million, the company achieved significant financial flexibility through successful debt refinancing and reduced operating cash burn. Valneva’s Lyme disease vaccine candidate, VLA15, is progressing well in its Phase 3 study, with results expected in 2026. The company also highlighted the growth in sales of its Japanese encephalitis vaccine and the launch of its chikungunya vaccine, IXCHIQ®, despite regulatory challenges in the U.S.

The most recent analyst rating on (VALN) stock is a Hold with a $8.50 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Valneva Reports Increased Revenues and Strategic Advances in Vaccine Development
Nov 20, 2025

On November 20, 2025, Valneva SE reported its financial results for the first nine months of 2025, highlighting an 8.9% increase in total revenues to €127.0 million compared to the same period in 2024. The company achieved significant financial flexibility through successful debt refinancing and reduced operating cash burn. Despite a net loss of €65.2 million, Valneva’s commercial portfolio showed growth, particularly in its Japanese encephalitis vaccine sales. The company is advancing its Lyme disease vaccine candidate with Pfizer, expecting Phase 3 results in 2026, and is also progressing with its Shigella vaccine candidate, which received Fast Track designation from the FDA.

The most recent analyst rating on (VALN) stock is a Buy with a $18.00 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Valneva Reports Positive Phase 1 Results for Zika Vaccine Candidate
Nov 4, 2025

Valneva SE announced positive results from its Phase 1 clinical trial of VLA1601, a second-generation adjuvanted inactivated vaccine candidate against the Zika virus. Conducted in the United States with approximately 150 participants, the trial demonstrated that VLA1601 was generally safe and well tolerated, with no safety concerns identified. The strongest immune response was observed in the double-adjuvant treatment arms, showing significantly higher neutralizing antibody titers compared to the single-adjuvant arm. These results indicate an improved immune response over the first-generation vaccine candidate, but further development will depend on securing major funding opportunities.

The most recent analyst rating on (VALN) stock is a Buy with a $18.00 price target. To see the full list of analyst forecasts on Valneva stock, see the VALN Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 28, 2025