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Sana Biotechnology (SANA)
NASDAQ:SANA
US Market
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Sana Biotechnology (SANA) AI Stock Analysis

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SANA

Sana Biotechnology

(NASDAQ:SANA)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$3.00
▼(-14.77% Downside)
Action:Reiterated
Date:06/06/26
The score is held down primarily by weak financial performance (no revenue, sizable losses, and negative free cash flow) and bearish technicals (below major moving averages with negative MACD/low RSI). Offsetting factors are limited, with corporate events providing some liquidity support via recent equity raises, while valuation signals are constrained by negative earnings and no dividend.
Positive Factors
Strategic partnership & equity investment
The Mayo Clinic equity investment and collaboration tie capital to program-specific development (SC451 and islet cell products), extending runway assumptions and aligning a major clinical partner with Sana’s R&D. This structural partnership strengthens program execution odds and access to clinical expertise over multiple years.
Negative Factors
No commercial revenue
Sana remains fully pre-revenue, meaning long-term value creation depends entirely on successful clinical development and eventual commercialization. This structural lack of operating revenue raises execution and financing dependency risk and implies outcomes hinge on binary clinical and regulatory milestones.
Read all positive and negative factors
Positive Factors
Negative Factors
Strategic partnership & equity investment
The Mayo Clinic equity investment and collaboration tie capital to program-specific development (SC451 and islet cell products), extending runway assumptions and aligning a major clinical partner with Sana’s R&D. This structural partnership strengthens program execution odds and access to clinical expertise over multiple years.
Read all positive factors

Sana Biotechnology (SANA) vs. SPDR S&P 500 ETF (SPY)

Sana Biotechnology Business Overview & Revenue Model

Company Description
Sana Biotechnology, Inc. is a biotechnology firm focused on creating treatments using engineered cells. The company develops advanced ex vivo and in vivo cell engineering platforms to address a range of conditions with significant unmet medical ne...
How the Company Makes Money
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Sana Biotechnology Financial Statement Overview

Summary
Development-stage profile with no revenue and large ongoing losses (TTM net loss ~$242M) plus continued cash burn (TTM FCF about -$134M). Operating losses have narrowed versus prior years and leverage is moderate (TTM debt-to-equity ~0.63), but equity has eroded sharply over time, keeping financial strength constrained and elevating funding/dilution risk.
Income Statement
12
Very Negative
Balance Sheet
38
Negative
Cash Flow
22
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-2.39M-12.75M0.000.000.000.00
EBITDA-180.09M-178.21M-255.33M-268.58M-256.94M-345.84M
Net Income-241.99M-244.17M-266.76M-283.25M-269.48M-355.93M
Balance Sheet
Total Assets373.59M416.89M501.02M565.30M822.72M1.13B
Cash, Cash Equivalents and Short-Term Investments101.14M138.38M152.50M205.19M423.96M551.00M
Total Debt75.33M78.86M94.20M104.10M108.25M110.94M
Total Liabilities254.35M256.01M250.52M277.79M323.40M400.90M
Stockholders Equity119.24M160.88M250.50M287.51M499.31M728.50M
Cash Flow
Free Cash Flow-133.64M-144.77M-256.58M-273.61M-310.93M-280.92M
Operating Cash Flow-132.55M-143.83M-223.15M-253.58M-290.05M-251.05M
Investing Cash Flow-7.40M-40.24M17.45M172.01M210.56M-245.80M
Financing Cash Flow127.62M128.73M199.75M31.65M4.91M631.75M

Sana Biotechnology Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.52
Price Trends
50DMA
3.24
Negative
100DMA
3.60
Negative
200DMA
3.85
Negative
Market Momentum
MACD
-0.09
Positive
RSI
31.37
Neutral
STOCH
14.81
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SANA, the sentiment is Negative. The current price of 3.52 is above the 20-day moving average (MA) of 3.15, above the 50-day MA of 3.24, and below the 200-day MA of 3.85, indicating a bearish trend. The MACD of -0.09 indicates Positive momentum. The RSI at 31.37 is Neutral, neither overbought nor oversold. The STOCH value of 14.81 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for SANA.

Sana Biotechnology Risk Analysis

Sana Biotechnology disclosed 82 risk factors in its most recent earnings report. Sana Biotechnology reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Sana Biotechnology Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$1.58B-15.53-56.07%3.42%-11.04%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$5.00B-8.76-30.88%-89.11%-37.55%
49
Neutral
$750.58M-11.25-28.90%68.64%50.57%
46
Neutral
$415.88M-2.43-677.38%7.97%59.82%
43
Neutral
$745.82M-3.07-161.87%-6.15%
42
Neutral
$552.69M-2.73-188.82%4.89%24.20%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
SANA
Sana Biotechnology
2.69
-0.14
-4.95%
GERN
Geron
1.13
-0.49
-30.25%
EDIT
Editas Medicine
2.65
0.72
37.05%
CRSP
Crispr Therapeutics AG
51.60
9.51
22.59%
TSHA
Taysha Gene Therapies
5.43
2.63
93.93%
PRME
Prime Medicine, Inc.
2.96
1.29
77.25%

Sana Biotechnology Corporate Events

Executive/Board ChangesShareholder Meetings
Sana Biotechnology Shareholders Reelect Directors and Ratify Auditor
Positive
Jun 5, 2026
Sana Biotechnology, Inc. reported the outcomes of its 2026 annual meeting of stockholders, held on June 4, 2026, where shareholders elected all Class II director nominees to serve three-year terms expiring at the 2029 annual meeting. The vote reaf...
Business Operations and StrategyPrivate Placements and Financing
Sana Biotechnology Raises $69 Million Through Equity Offering
Positive
May 15, 2026
On May 15, 2026, Sana Biotechnology, Inc. reported that it had sold a total of 21,607,878 shares of its common stock under an amended and restated sales agreement with TD Securities (USA) LLC, which acted as the sales agent. The transaction genera...
Executive/Board ChangesRegulatory Filings and Compliance
Sana Biotechnology Rebalances Board Classes With Director Shift
Neutral
Apr 24, 2026
Sana Biotechnology, Inc. announced a governance adjustment on April 22, 2026, to rebalance its Board of Directors in line with its Amended and Restated Certificate of Incorporation. To achieve a more equal distribution across three director classe...
Business Operations and StrategyPrivate Placements and Financing
Sana Biotechnology Secures Strategic Equity Investment from Mayo
Positive
Apr 13, 2026
On April 10, 2026, Sana Biotechnology entered into a stock purchase agreement with Mayo Clinic under which Mayo Clinic will buy 7,507,507 shares at $3.33 per share for roughly $25 million, with an option to purchase an additional 7,507,507 shares ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 06, 2026