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Inventiva (IVA)
NASDAQ:IVA
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Inventiva (IVA) AI Stock Analysis

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IVA

Inventiva

(NASDAQ:IVA)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
$4.00
▼(-2.44% Downside)
Inventiva's overall stock score is primarily impacted by its poor financial performance, characterized by persistent losses and negative margins. The technical analysis further indicates a bearish trend, while the valuation metrics highlight ongoing financial challenges. The absence of earnings call data and corporate events does not influence the score.
Positive Factors
Strategic Leadership Change
The appointment of Andrew Obenshain as CEO is a strategic move to enhance U.S. market expansion. His experience in drug approvals and commercialization is expected to strengthen Inventiva's position in the MASH field, potentially driving long-term growth and market presence.
R&D Investment
The $100 million ATM program aims to finance R&D for lanifibranor and other projects. This investment supports ongoing clinical trials and strengthens Inventiva's financial position, potentially enhancing its competitive edge in the biotechnology sector.
Revenue Growth
The substantial revenue growth indicates successful product development partnerships and licensing agreements. This trend, if sustained, could improve financial stability and support long-term strategic goals.
Negative Factors
Financial Instability
Negative stockholders' equity and high liabilities indicate financial distress, limiting Inventiva's ability to invest in growth opportunities and posing risks to its long-term sustainability.
Cash Flow Challenges
Negative cash flows suggest Inventiva is not generating sufficient cash from operations, which may hinder its ability to fund R&D and other strategic initiatives, impacting long-term viability.
Profitability Issues
Ongoing losses and negative margins reflect operational inefficiencies. This persistent lack of profitability could strain resources and limit the company's capacity to achieve sustainable growth.

Inventiva (IVA) vs. SPDR S&P 500 ETF (SPY)

Inventiva Business Overview & Revenue Model

Company DescriptionInventiva S.A., a clinical-stage biopharmaceutical company, focuses on the development of oral small molecule therapies for the treatment of non-alcoholic steatohepatitis (NASH), mucopolysaccharidoses (MPS), and other diseases. Its lead product candidate is Lanifibranor, which has completed Phase IIb clinical trial to treat NASH. The company also develops Odiparcil, which has completed Phase IIa clinical trial for the treatment of MPS VI subtype disease. In addition, it has a pipeline of earlier stage programs in oncology and other diseases. The company has strategic collaboration with AbbVie for the treatment of autoimmune diseases; and Boehringer Ingelheim International GmbH for developing new treatments for idiopathic pulmonary fibrosis. Inventiva S.A. was founded in 2011 and is based in Daix, France.
How the Company Makes MoneyInventiva generates revenue through a combination of product development partnerships, licensing agreements, and potential milestone payments from its collaborations with larger pharmaceutical companies. The company typically enters into strategic alliances that allow it to share the costs and risks associated with drug development while also receiving upfront payments and royalties based on the sales of partnered products. Additionally, Inventiva may receive funding through grants and public financing aimed at supporting research in rare diseases and metabolic disorders, contributing to its financial sustainability.

Inventiva Earnings Call Summary

Earnings Call Date:Sep 29, 2025
(Q4-2024)
|
% Change Since: |
Next Earnings Date:Apr 01, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant progress in the clinical development of lanifibranor, positive trial results, and a strong financial position bolstered by recent financing activities. However, challenges such as workforce reduction and decreased revenue were noted. The sentiment remains cautiously optimistic with strategic partnerships and governance strengthening, despite financial and operational challenges.
Q4-2024 Updates
Positive Updates
Significant Progress in Lanifibranor Clinical Development
Completed screening of Phase 3 NATiV3 trial in early January 2025, targeting recruitment completion in H1 2025. Three data monitoring committee meetings with positive recommendations for continuation without protocol modification.
Positive Results from LEGEND Trial
Statistically significant reduction in HBA1C with lanifibranor alone and in combination, improved insulin sensitivity, and significant improvement in markers of liver injury. Combination with empagliflozin mitigates weight gain.
Strong Financial Position
Raised approximately $184 million in gross proceeds from several financing operations, including a $125 million structured financing. Cash position at the end of 2024 was €96.6 million, a net positive variance of close to €61 million from the previous year.
Strategic Partnerships and Market Expansion
Partner Hepalys launched clinical development of lanifibranor in Japan. Licensing agreements in place in Japan, South Korea, and China position lanifibranor as a leading oral drug in MASH in these regions.
Strengthened Governance and Team
Reinforced Board of Directors with three new members, including Mark Pruzanski as Chairman. Reinforced development team to prepare for regulatory filing and potential commercial launch of lanifibranor.
Negative Updates
Reduction in Workforce
Decision to stop all pre-clinical activities not related to lanifibranor, leading to a reduction of approximately 50% of the workforce.
Decreased Revenue
Recorded revenues of €9.2 million in 2024, compared to €17.5 million in 2023, primarily due to the timing of milestone payments.
Increased Net Loss
Net loss for the full year 2024 was €184.2 million, compared to €110.4 million in 2023, driven by non-cash financial items and increased expenses.
Company Guidance
During the Inventiva Full Year 2024 Financial Results Webcast and Conference Call, key guidance and metrics were provided by the company's leadership. CEO Frédéric Cren highlighted the significant progress in the clinical development of lanifibranor, emphasizing the closing of screening for the Phase 3 NATiV3 trial and targeting recruitment completion in H1 2025. The topline results are expected in the second half of 2026, with potential U.S. approval by March. The call also addressed the company's financial position, with a cash runway extending to September 2025, and potentially September 2026 after securing additional financing. The 2024 financial highlights included a cash position of €96.6 million, revenues of €9.2 million, and a net loss of €184.2 million. The company also discussed strategic decisions, such as focusing resources on lanifibranor development, which led to a reduction in workforce by approximately 50%. The call concluded with a discussion on potential partnerships and long-term plans for commercialization.

Inventiva Financial Statement Overview

Summary
Inventiva is facing substantial financial difficulties with persistent losses, negative margins, and significant reliance on external financing. The income statement, balance sheet, and cash flow statement all indicate financial distress, with negative equity and poor cash flow generation.
Income Statement
35
Negative
Inventiva's income statement highlights significant challenges in profitability. The company reports consistent negative net income and EBIT over the years. The revenue growth rate is volatile, with a decrease in the most recent year. Both gross profit and net profit margins are negative, indicating that the company is struggling to cover its costs. EBITDA margin is also highly negative, showcasing operational inefficiencies.
Balance Sheet
30
Negative
Inventiva's balance sheet reveals financial instability with negative stockholders' equity and a high total liabilities figure. The debt-to-equity ratio is not applicable due to negative equity, and return on equity is also negative, reflecting poor returns on shareholders' investments. The equity ratio is negative, further indicating financial distress and a reliance on liabilities.
Cash Flow
40
Negative
The cash flow statement indicates persistent negative operating and free cash flows, suggesting that Inventiva is not generating enough cash from its operations to sustain its business activities. While there is a significant financing cash flow, likely from debt or equity raises, the operating cash flow to net income ratio and free cash flow to net income ratio are weak, pointing towards cash flow challenges.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue9.20M17.48M12.18M4.19M372.00K
Gross Profit9.20M17.50M17.06M4.19M4.42M
EBITDA-166.53M-102.04M-56.29M-52.76M-31.77M
Net Income-184.21M-110.43M-54.27M-49.64M-33.62M
Balance Sheet
Total Assets118.97M69.56M116.00M121.98M138.92M
Cash, Cash Equivalents and Short-Term Investments96.56M27.34M87.78M86.55M113.02M
Total Debt54.33M37.49M34.51M10.12M10.06M
Total Liabilities225.61M101.59M70.53M33.12M27.71M
Stockholders Equity-106.65M-32.03M45.48M88.87M111.21M
Cash Flow
Free Cash Flow-86.26M-82.15M-45.49M-48.16M-30.88M
Operating Cash Flow-85.93M-81.61M-44.93M-47.63M-30.59M
Investing Cash Flow8.74M-7.73M8.87M-1.79M-8.56M
Financing Cash Flow145.59M29.08M37.27M25.45M111.67M

Inventiva Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.10
Price Trends
50DMA
5.40
Negative
100DMA
4.48
Negative
200DMA
3.79
Positive
Market Momentum
MACD
-0.34
Positive
RSI
41.11
Neutral
STOCH
7.58
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IVA, the sentiment is Negative. The current price of 4.1 is below the 20-day moving average (MA) of 4.91, below the 50-day MA of 5.40, and above the 200-day MA of 3.79, indicating a neutral trend. The MACD of -0.34 indicates Positive momentum. The RSI at 41.11 is Neutral, neither overbought nor oversold. The STOCH value of 7.58 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for IVA.

Inventiva Risk Analysis

Inventiva disclosed 83 risk factors in its most recent earnings report. Inventiva reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Inventiva Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$916.49M10.85%-1.41%
47
Neutral
$866.69M-65.10%-5.18%
46
Neutral
$732.89M-55.41%-22.52%-37.00%
45
Neutral
$658.57M-53.16%636.99%27.10%
41
Neutral
$616.04M-0.99-12.52%-82.84%
38
Underperform
$922.03M-56.28%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IVA
Inventiva
4.18
1.41
50.90%
IOVA
Iovance Biotherapeutics
1.81
-8.77
-82.89%
KURA
Kura Oncology
9.94
-7.74
-43.78%
URGN
Urogen Pharma
19.31
7.19
59.32%
MRVI
Maravai Lifesciences Holdings
2.89
-2.19
-43.11%
MBX
MBX Biosciences, Inc.
24.74
1.83
7.99%

Inventiva Corporate Events

Inventiva Announces General Meeting to Discuss Strategic Resolutions
Oct 20, 2025

On October 20, 2025, Inventiva S.A. announced the upcoming Ordinary and Extraordinary General Meeting scheduled for November 27, 2025, in Paris, France. The meeting will address several key agenda items, including the approval of the CEO’s compensation policy, a settlement agreement with Mr. Frédéric Cren, and the authorization for the Board to grant share options. These resolutions reflect Inventiva’s strategic focus on aligning executive compensation with company performance and expanding its capital structure to support future growth, potentially impacting shareholder value and employee incentives.

Inventiva Launches $100 Million ATM Program to Boost R&D Efforts
Oct 14, 2025

On October 14, 2025, Inventiva announced the implementation of a new At-The-Market (ATM) program, filing a shelf registration statement with the SEC to issue and sell ordinary shares in the form of American Depositary Shares (ADS) for up to $100 million. The proceeds are intended to finance the research and development of lanifibranor, working capital requirements, and general corporate purposes. The ATM program allows for sales to eligible investors, with the new shares to be traded on Euronext Paris and Nasdaq. This strategic move aims to strengthen Inventiva’s financial position and support its ongoing clinical trials, potentially impacting its market positioning and stakeholder interests.

Inventiva Appoints Andrew Obenshain as CEO to Drive U.S. Market Expansion
Oct 1, 2025

On October 1, 2025, Inventiva announced the appointment of Andrew Obenshain as the new Chief Executive Officer, succeeding co-founder Frédéric Cren. This leadership change is part of a strategic move to support Inventiva’s growth, particularly in preparing for potential commercialization in the U.S. market for MASH. Obenshain’s global experience in drug approvals and commercialization is expected to strengthen Inventiva’s position in the MASH field and advance the development of lanifibranor, a promising oral therapy for MASH.

Inventiva S.A. Reports Significant Revenue Growth Amid Rising Losses
Sep 29, 2025

On September 29, 2025, Inventiva S.A. released its unaudited financial results for the first half of 2025, revealing a significant increase in revenues to €4,454,000 from €41,000 in the same period last year. Despite this revenue growth, the company reported a net loss of €175,882,000, which is a substantial increase from the previous year’s loss of €49,029,000. The financial update highlights the company’s ongoing challenges in managing its expenses, particularly in research and development and general administrative costs, which have impacted its financial performance.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 30, 2025