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Entrada Therapeutics Inc (TRDA)
NASDAQ:TRDA
US Market
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Entrada Therapeutics Inc (TRDA) AI Stock Analysis

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TRDA

Entrada Therapeutics Inc

(NASDAQ:TRDA)

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Neutral 54 (OpenAI - 4o)
Rating:54Neutral
Price Target:
$7.50
▼(-25.60% Downside)
Entrada Therapeutics Inc's overall stock score is primarily influenced by its financial challenges, including declining revenues and persistent losses. Despite these issues, the stock exhibits strong technical momentum, which boosts its score. However, valuation concerns due to negative earnings and lack of dividends weigh down the overall assessment.
Positive Factors
Proprietary Technology
The TET platform provides a competitive edge by enabling effective delivery of therapeutic agents, potentially leading to successful treatments and partnerships.
Partnerships and Collaborations
Strong partnerships with pharmaceutical firms enhance revenue potential and provide financial support for R&D, crucial for long-term growth in biotech.
Low Leverage
Low leverage provides financial stability and flexibility, reducing risk and allowing the company to focus on R&D and strategic growth initiatives.
Negative Factors
Declining Revenues
Declining revenues indicate challenges in product commercialization and market penetration, impacting long-term financial sustainability.
Cash Flow Challenges
Negative cash flow limits the company's ability to invest in R&D and scale operations, potentially hindering growth and innovation efforts.
Profitability Issues
Ongoing profitability issues suggest operational inefficiencies and high costs, which could strain resources and affect long-term viability.

Entrada Therapeutics Inc (TRDA) vs. SPDR S&P 500 ETF (SPY)

Entrada Therapeutics Inc Business Overview & Revenue Model

Company DescriptionEntrada Therapeutics, Inc., a biotechnology company, develops endosomal escape vehicle (EEV) therapeutics for the treatment of multiple neuromuscular diseases. Its endosomal escape vehicle platform develops a portfolio of oligonucleotide, antibody, and enzyme-based programs. The company's lead product candidate is ENTR-601-44, which is in preclinical trail for the treatment of Duchenne muscular dystrophy and myotonic dystrophy type 1. It also engages in the development of EEV-PMO-CAG for the treatment of myotonic dystrophy type 1. The company was formerly known as CycloPorters, Inc. and changed its name to Entrada Therapeutics, Inc. in October 2017. Entrada Therapeutics, Inc. was incorporated in 2016 and is headquartered in Boston, Massachusetts.
How the Company Makes MoneyEntrada Therapeutics generates revenue through a combination of product development partnerships, grants, and potential future product sales. The company collaborates with pharmaceutical firms and research organizations to develop its therapies, often receiving milestone payments and royalties from these partnerships. Additionally, Entrada may receive funding from government and non-profit organizations aimed at supporting research in rare and genetic diseases. As the company advances its drug candidates through clinical trials, it may also attract further investments and partnerships, enhancing its revenue potential.

Entrada Therapeutics Inc Financial Statement Overview

Summary
Entrada Therapeutics Inc is facing significant financial challenges, with declining revenues and persistent losses impacting profitability. While the company maintains a stable balance sheet with low leverage, cash flow issues persist. The biotechnology industry often involves high R&D costs and long development cycles, which may contribute to the current financial performance.
Income Statement
35
Negative
Entrada Therapeutics Inc has experienced a significant decline in revenue with a negative growth rate of -22.59% in the TTM period. The company is facing challenges with profitability, as evidenced by negative net profit and EBIT margins. Despite a high gross profit margin, the overall financial performance is hindered by substantial operating losses.
Balance Sheet
50
Neutral
The company maintains a relatively low debt-to-equity ratio of 0.15, indicating conservative leverage. However, the return on equity is negative, reflecting ongoing losses. The equity ratio is stable, suggesting a solid capital structure despite profitability challenges.
Cash Flow
40
Negative
Operating cash flow and free cash flow are both negative, indicating cash flow challenges. The free cash flow to net income ratio is slightly above 1, suggesting some alignment between cash flow and accounting profits, but the overall cash flow position remains weak.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue61.52M210.78M129.01M0.000.000.00
Gross Profit23.16M210.78M129.01M0.000.00-326.00K
EBITDA-113.78M47.01M-321.00K-95.35M-50.01M-26.20M
Net Income-103.45M65.63M-6.68M-94.62M-51.16M-26.52M
Balance Sheet
Total Assets412.90M526.32M469.19M252.06M305.83M43.53M
Cash, Cash Equivalents and Short-Term Investments326.84M420.00M351.97M188.71M291.06M39.05M
Total Debt52.40M59.21M68.23M25.94M0.000.00
Total Liabilities72.18M97.64M226.83M39.50M7.12M85.02M
Stockholders Equity340.72M428.68M242.36M212.55M298.72M-41.49M
Cash Flow
Free Cash Flow-129.80M-44.72M134.19M-96.67M-55.44M-27.89M
Operating Cash Flow-127.91M-41.56M139.80M-93.79M-50.86M-25.57M
Investing Cash Flow141.05M-27.80M-138.40M-148.65M-4.58M-2.32M
Financing Cash Flow2.10M102.96M21.04M479.00K307.46M50.09M

Entrada Therapeutics Inc Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.08
Price Trends
50DMA
6.92
Positive
100DMA
6.35
Positive
200DMA
7.71
Positive
Market Momentum
MACD
0.92
Negative
RSI
77.14
Negative
STOCH
77.43
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TRDA, the sentiment is Positive. The current price of 10.08 is above the 20-day moving average (MA) of 8.20, above the 50-day MA of 6.92, and above the 200-day MA of 7.71, indicating a bullish trend. The MACD of 0.92 indicates Negative momentum. The RSI at 77.14 is Negative, neither overbought nor oversold. The STOCH value of 77.43 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for TRDA.

Entrada Therapeutics Inc Risk Analysis

Entrada Therapeutics Inc disclosed 93 risk factors in its most recent earnings report. Entrada Therapeutics Inc reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Entrada Therapeutics Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
60
Neutral
$219.11M-51.06%-44.94%-274.42%
54
Neutral
$385.25M-27.11%-71.42%-248.91%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$259.73M-59.98%-10.57%1.98%
44
Neutral
$219.49M-39.78%-38.23%
41
Neutral
$712.87M-45.35%36.65%
33
Underperform
$215.37M10.4219.23%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TRDA
Entrada Therapeutics Inc
10.08
-9.81
-49.32%
GNFT
Genfit SA
4.65
0.44
10.45%
BDTX
Black Diamond Therapeutics
3.78
1.13
42.64%
CCCC
C4 Therapeutics
2.68
-1.87
-41.10%
VTYX
Ventyx Biosciences
9.99
7.31
272.76%
SGMT
Sagimet Biosciences, Inc. Class A
7.08
1.39
24.43%

Entrada Therapeutics Inc Corporate Events

Entrada Therapeutics Reports Increased Losses Amid R&D Expansion
Nov 7, 2025

Entrada Therapeutics Inc., a clinical-stage biopharmaceutical company, focuses on developing innovative medicines that target intracellular mechanisms, primarily within the biotechnology sector. The company’s recent earnings report highlights a challenging quarter with a net loss of $44.1 million, reflecting increased research and development expenses as they advance their therapeutic programs. Key financial metrics indicate a decrease in collaboration revenue to $1.6 million for the quarter, down from $19.6 million the previous year, while operating expenses rose to $48.7 million. Despite these challenges, Entrada maintains a strong cash position with $326.8 million in cash, cash equivalents, and marketable securities, ensuring operational funding for at least the next twelve months. Looking ahead, the company remains focused on advancing its therapeutic candidates and leveraging its proprietary EEV platform to explore additional opportunities in the biopharmaceutical landscape.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 22, 2025