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Entrada Therapeutics Inc
(NASDAQ:TRDA)
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Rating:49Neutral
Price Target:
$7.50
▼(-46.39% Downside)
Action:Reiterated
Date:06/27/26
The score is held down primarily by sharply worsening recent financial performance (large losses and significant cash burn) despite a relatively manageable leverage profile. Technicals remain pressured with the stock below key longer-term moving averages and a negative MACD, while valuation offers limited support given ongoing losses and no dividend. Offsetting factors include positive corporate updates and pipeline progress alongside stated funding runway into Q3 2027.
Positive Factors
Diversified clinical pipeline
Entrada's portfolio spans multiple genetic indications (DMD, DM1, inherited retinal diseases), creating several staggered clinical catalysts through 2026. This diversification reduces binary single-program risk, increases chances of at least one de-risking event, and supports longer-term developer economics and partner interest.
Negative Factors
High cash burn
Sustained negative operating and free cash flow at ~-$132M TTM drains liquidity and forces reliance on external financing or partnerships. Over months this elevates dilution risk, constrains discretionary R&D spending, and pressures timeline flexibility for longer development programs if burn isn't reduced.
Read all positive and negative factors
Positive Factors
Negative Factors
Diversified clinical pipeline
Entrada's portfolio spans multiple genetic indications (DMD, DM1, inherited retinal diseases), creating several staggered clinical catalysts through 2026. This diversification reduces binary single-program risk, increases chances of at least one de-risking event, and supports longer-term developer economics and partner interest.
Read all positive factors
Entrada Therapeutics Inc (TRDA) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$299.70M
Dividend YieldN/A
Average Volume (3M)538.39K
Price to Earnings (P/E)―
Beta (1Y)1.17
Revenue Growth-96.67%
EPS Growth-559.52%
CountryUS
Employees183
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-4.00
Shares Outstanding38,820,618
10 Day Avg. Volume231,883
30 Day Avg. Volume538,394
Financial Highlights & Ratios
PEG Ratio<0.01
Price to Book (P/B)1.39
Price to Sales (P/S)16.73
P/FCF Ratio-3.28
Enterprise Value/Market Cap0.79
Enterprise Value/Revenue41.42
Enterprise Value/Gross Profit-6.93
Enterprise Value/Ebitda-1.44
Forecast
1Y Price Target
$18.75Price Target Upside34.02% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering7
EPS Forecast (FY)-3.91
Revenue Forecast (FY)$19.51M
Entrada Therapeutics Inc Business Overview & Revenue Model
Company Description
Entrada Therapeutics, Inc. operates as a biotechnology enterprise dedicated to pioneering endosomal escape vehicle (EEV) therapeutics, specifically engineered to tackle a range of neuromuscular ailments. The company leverages its proprietary EEV p...
How the Company Makes Money
Entrada Therapeutics is a clinical-stage biotech company and does not primarily generate recurring product sales because it does not have approved commercial products. The company’s funding and revenue, when present, generally come from a combinat...
Entrada Therapeutics Inc Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
66
Positive
Cash Flow
22
Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 5.74M | 25.42M | 210.78M | 129.01M | 0.00 | 0.00 |
| Gross Profit | -34.31M | 21.32M | 210.78M | 129.01M | 0.00 | 0.00 |
| EBITDA | -164.87M | -142.40M | 70.26M | 14.90M | -90.09M | -50.04M |
| Net Income | -166.12M | -143.75M | 65.63M | -6.68M | -94.62M | -51.16M |
Balance Sheet | ||||||
| Total Assets | 335.52M | 377.38M | 526.32M | 469.19M | 252.06M | 305.83M |
| Cash, Cash Equivalents and Short-Term Investments | 254.86M | 295.70M | 420.00M | 351.97M | 188.71M | 291.06M |
| Total Debt | 49.75M | 50.93M | 59.21M | 68.23M | 25.94M | 0.00 |
| Total Liabilities | 64.66M | 71.25M | 97.64M | 226.83M | 39.50M | 7.12M |
| Stockholders Equity | 270.85M | 306.13M | 428.68M | 242.36M | 212.55M | 298.72M |
Cash Flow | ||||||
| Free Cash Flow | -131.64M | -129.55M | -44.72M | 134.19M | -96.67M | -55.44M |
| Operating Cash Flow | -131.70M | -128.51M | -41.56M | 139.80M | -93.79M | -50.86M |
| Investing Cash Flow | 139.01M | 116.81M | -27.80M | -138.40M | -148.65M | -4.58M |
| Financing Cash Flow | 637.00K | 887.00K | 102.96M | 21.04M | 479.00K | 307.46M |
Entrada Therapeutics Inc Technical Analysis
Neutral
13.99
Price Trends
8.24
Negative
10.35
Negative
9.55
Negative
Market Momentum
-0.04
Negative
51.40
Neutral
66.14
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TRDA, the sentiment is Neutral. The current price of 13.99 is above the 20-day moving average (MA) of 6.97, above the 50-day MA of 8.24, and above the 200-day MA of 9.55, indicating a neutral trend. The MACD of -0.04 indicates Negative momentum. The RSI at 51.40 is Neutral, neither overbought nor oversold. The STOCH value of 66.14 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for TRDA.
Entrada Therapeutics Inc Risk Analysis
Entrada Therapeutics Inc disclosed 93 risk factors in its most recent earnings report. Entrada Therapeutics Inc reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Entrada Therapeutics Inc Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
60 Neutral | $475.44M | -3.48 | -50.68% | ― | -12.37% | 19.59% | |
52 Neutral | $465.61M | -5.73 | -37.57% | ― | ― | 24.50% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
49 Neutral | $299.70M | -1.88 | -51.22% | ― | -96.67% | -559.52% | |
46 Neutral | $115.18M | -2.59 | -36.37% | ― | -100.00% | -1056.82% |
* Healthcare Sector Average
TRDA
Entrada Therapeutics Inc
7.53
0.37
5.17%
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SGMT
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-15.41%
Entrada Therapeutics Inc Corporate Events
Business Operations and StrategyExecutive/Board ChangesShareholder Meetings
Entrada Therapeutics Stockholders Approve Directors and Equity Plans
Positive
Jun 10, 2026
Entrada Therapeutics Inc. held its Annual Meeting of stockholders on June 10, 2026, with 33,190,234 of 38,820,616 eligible common shares represented, establishing a quorum for all matters up for vote. Stockholders elected Peter S. Kim, Ph.D., and ...
Business Operations and StrategyRegulatory Filings and Compliance
Entrada Therapeutics Highlights Transformational Year and Pipeline Progress
Positive
May 19, 2026
On May 18, 2026, Entrada Therapeutics updated its corporate presentation to highlight what it calls a transformational year, underscored by five clinical-stage programs in Duchenne muscular dystrophy and myotonic dystrophy type 1 and a deepening p...
Business Operations and StrategyFinancial Disclosures
Entrada posts strong ENTR-601-44 Duchenne Phase 1/2 data
Positive
May 7, 2026
On May 7, 2026, Entrada Therapeutics reported first-quarter 2026 results and unveiled positive topline data from Cohort 1 of its Phase 1/2 ELEVATE-44-201 trial of ENTR-601-44 in boys with Duchenne muscular dystrophy amenable to exon 44 skipping. P...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.