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Entrada Therapeutics Inc (TRDA)
NASDAQ:TRDA
US Market
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Entrada Therapeutics Inc (TRDA) AI Stock Analysis

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TRDA

Entrada Therapeutics Inc

(NASDAQ:TRDA)

Rating:60Neutral
Price Target:
$6.50
▲(25.24% Upside)
The overall stock score for Entrada Therapeutics Inc. is primarily influenced by its strong financial performance and attractive valuation. However, bearish technical indicators and recent declines in revenue and net income temper the outlook. The strategic board appointment is a positive development, but the company's ability to manage cash flows and sustain growth remains critical.
Positive Factors
Clinical Development
Multiple candidates advancing in clinical development positions Entrada favorably to become a one-stop shop for DMD patients needing exon-skipping therapies.
Financial Stability
Entrada ended with $354M in cash, expected to be sufficient to fund operations into 2Q27.
Regulatory Progress
Key regulatory clearances obtained, clearing path for multiple global clinical development programs to advance.
Negative Factors
Clinical Risks
Risks include failure to generate favorable mid-stage clinical data and inability to advance lead candidates into pivotal trials in a timely manner.
Financial Performance
Entrada Therapeutics recorded top-line revenue of ~$2M, missing the forecast of $8M.
Partnership and Dilution Risks
Risks include partnership risks and long-term dilution risk.

Entrada Therapeutics Inc (TRDA) vs. SPDR S&P 500 ETF (SPY)

Entrada Therapeutics Inc Business Overview & Revenue Model

Company DescriptionEntrada Therapeutics Inc (TRDA) is a biotechnology company focused on developing intracellular biologics to treat devastating diseases. The company operates in the biotechnology sector, specializing in the development of novel therapeutics that can target intracellular disease drivers, addressing challenges associated with delivering biologics into cells. Entrada's core products include its proprietary Endosomal Escape Vehicle (EEV) technology, which is designed to enable the delivery of various therapeutic modalities, including nucleic acids, peptides, and proteins, directly into the cell cytosol.
How the Company Makes MoneyEntrada Therapeutics generates revenue through strategic collaborations and partnerships with other pharmaceutical and biotechnology companies. These partnerships often involve licensing their proprietary EEV technology for the development of therapies targeting specific diseases, leading to potential milestone payments and royalties based on the success of the partnered products. Additionally, Entrada may earn revenue from government grants or research funding to support its innovative therapeutic projects. As the company advances its own pipeline of investigational drugs, future revenue could also come from the commercialization of its proprietary therapeutics, contingent upon successful clinical trials and regulatory approval.

Entrada Therapeutics Inc Financial Statement Overview

Summary
Entrada Therapeutics Inc. has shown impressive revenue growth and improving profitability over the past years. However, recent declines in revenue and net income, coupled with negative cash flow, highlight the need for strategic management to sustain growth and financial stability.
Income Statement
65
Positive
Entrada Therapeutics Inc. has demonstrated significant revenue growth over recent years, with a notable increase in total revenue from $0 in 2021 to $210.78 million in 2024. The company achieved a positive net income of $65.63 million in 2024, indicating improving profitability. However, the TTM data shows a decline in revenue to $172.22 million and net income to $24.78 million, suggesting recent challenges. Gross profit margins have been strong, and the EBIT and EBITDA margins indicate operational efficiency improvements. Despite these, the recent dip in revenue and earnings raises concerns about sustaining growth momentum.
Balance Sheet
70
Positive
The balance sheet reveals a solid equity position with a stockholders' equity of $417.26 million in the latest TTM. The debt-to-equity ratio remains low, indicating prudent financial leverage. The company's total assets have grown significantly, and cash reserves are robust, reflecting strong liquidity. However, the stability of equity amidst fluctuating liabilities warrants attention. Overall, the balance sheet showcases financial stability, though vigilance is needed to maintain a low leverage profile.
Cash Flow
55
Neutral
Cash flow analysis shows a volatile operating cash flow, with the latest TTM indicating a negative figure of $-54.55 million. Free cash flow has also been negative, reflecting high capital expenditures relative to cash generated from operations. The substantial financing cash flow suggests reliance on external funding to support operations. While capital investments are necessary for growth, the persistent cash outflows pose a risk if not offset by future revenue increases.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue210.78M129.01M0.000.000.00
Gross Profit207.01M29.13M-1.90M-1.12M-326.00K
EBITDA47.01M-321.00K-95.35M-50.01M-26.34M
Net Income65.63M-6.68M-87.46M-50.07M-26.38M
Balance Sheet
Total Assets526.32M469.19M252.06M305.83M43.53M
Cash, Cash Equivalents and Short-Term Investments420.00M351.97M45.16M291.06M39.05M
Total Debt59.21M68.23M25.94M0.000.00
Total Liabilities97.64M226.83M39.50M7.12M85.02M
Stockholders Equity428.68M242.36M212.55M298.72M-41.49M
Cash Flow
Free Cash Flow-44.72M134.19M-96.67M-55.44M-27.89M
Operating Cash Flow-41.56M139.80M-93.79M-50.86M-25.57M
Investing Cash Flow-27.80M-138.40M-148.65M-4.58M-2.32M
Financing Cash Flow102.96M21.04M479.00K307.46M50.09M

Entrada Therapeutics Inc Technical Analysis

Technical Analysis Sentiment
Negative
Last Price5.19
Price Trends
50DMA
6.92
Negative
100DMA
7.80
Negative
200DMA
11.75
Negative
Market Momentum
MACD
-0.40
Positive
RSI
30.53
Neutral
STOCH
27.32
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For TRDA, the sentiment is Negative. The current price of 5.19 is below the 20-day moving average (MA) of 6.15, below the 50-day MA of 6.92, and below the 200-day MA of 11.75, indicating a bearish trend. The MACD of -0.40 indicates Positive momentum. The RSI at 30.53 is Neutral, neither overbought nor oversold. The STOCH value of 27.32 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for TRDA.

Entrada Therapeutics Inc Risk Analysis

Entrada Therapeutics Inc disclosed 94 risk factors in its most recent earnings report. Entrada Therapeutics Inc reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Entrada Therapeutics Inc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (47)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$568.61M5.86376.09%105.62%
60
Neutral
$197.41M7.36-18.12%-66.80%-157.68%
58
Neutral
$612.03M-115.47%
57
Neutral
$681.24M-87.42%-100.32%-197.69%
47
Neutral
$309.76M-48.57%-100.00%83.98%
47
Neutral
C$190.13M-2.29-23.77%3.17%17.53%1.84%
43
Neutral
$227.48M-59.60%-100.00%31.43%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
TRDA
Entrada Therapeutics Inc
5.19
-9.02
-63.48%
RIGL
Rigel
31.70
20.45
181.78%
BNTC
Benitec Biopharma
11.80
2.56
27.71%
ALLO
Allogene Therapeutics
1.04
-1.32
-55.93%
AMLX
Amylyx Pharmaceuticals Inc
7.64
5.66
285.86%
ZBIO
Zenas BioPharma, Inc.
14.63
-3.34
-18.59%

Entrada Therapeutics Inc Corporate Events

Executive/Board ChangesShareholder Meetings
Entrada Therapeutics Holds Virtual Annual Stockholders Meeting
Neutral
Jun 11, 2025

On June 11, 2025, Entrada Therapeutics, Inc. held its Annual Meeting of Stockholders virtually, where a quorum was established with 30,259,526 shares represented. During the meeting, stockholders elected three Class I directors to the Board and ratified the appointment of Ernst & Young LLP as the independent registered public accounting firm for the fiscal year ending December 31, 2025.

The most recent analyst rating on (TRDA) stock is a Buy with a $25.00 price target. To see the full list of analyst forecasts on Entrada Therapeutics Inc stock, see the TRDA Stock Forecast page.

Executive/Board ChangesBusiness Operations and Strategy
Entrada Therapeutics Appoints New Board Member
Positive
Jun 3, 2025

On May 30, 2025, Entrada Therapeutics expanded its Board of Directors from six to seven members, appointing Maha Radhakrishnan, M.D., as a Class III director and a member of the Audit Committee, effective June 1, 2025. Dr. Radhakrishnan brings extensive experience in global drug development, which is expected to support Entrada’s clinical momentum, particularly in advancing its Duchenne muscular dystrophy programs. Her appointment is seen as a strategic move to enhance the company’s capability in delivering innovative therapies for serious illnesses.

The most recent analyst rating on (TRDA) stock is a Buy with a $25.00 price target. To see the full list of analyst forecasts on Entrada Therapeutics Inc stock, see the TRDA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 08, 2025