Synlogic (SYBX)
OTHER OTC:SYBX
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Synlogic
(OTC:SYBX)
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Rating:49Neutral
Price Target:
$0.64
▼(-47.21% Downside)
Action:Upgraded
Date:05/15/26
The score is held down primarily by weak fundamentals—near-zero revenue, continued negative operating/free cash flow, and a materially reduced equity/asset base—despite improved loss and burn trends and no reported debt. Technicals are only mildly supportive in the near term, and valuation looks optically low on P/E but is less meaningful given the current business and cash-flow profile.
Positive Factors
No reported debt
Zero reported debt materially reduces financial risk and interest burden, improving strategic flexibility. Over a multi-month horizon this lowers bankruptcy and interest-coverage risk, giving management more optionality for financing development programs or pursuing partnerships without immediate debt service constraints.
Negative Factors
Near-zero recurring revenue
With essentially no recurring product revenue, the company remains fully reliant on collaborations, milestones, or financing. That structural absence of commercial cash flow keeps long-term sustainability dependent on clinical success or external funding, raising execution and dilution risk over the next several months.
Read all positive and negative factors
Positive Factors
Negative Factors
No reported debt
Zero reported debt materially reduces financial risk and interest burden, improving strategic flexibility. Over a multi-month horizon this lowers bankruptcy and interest-coverage risk, giving management more optionality for financing development programs or pursuing partnerships without immediate debt service constraints.
Read all positive factors
Synlogic (SYBX) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$7.34M
Dividend YieldN/A
Average Volume (3M)41.08K
Price to Earnings (P/E)2.8
Beta (1Y)0.52
Revenue GrowthN/A
EPS Growth-138.25%
CountryUS
Employees1
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)N/A
Shares Outstanding11,696,641
10 Day Avg. Volume24,108
30 Day Avg. Volume41,078
Financial Highlights & Ratios
PEG Ratio0.14
Price to Book (P/B)1.16
Price to Sales (P/S)0.00
P/FCF Ratio-3.16
Enterprise Value/Market Cap-0.87
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/Ebitda1.62
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
Synlogic Business Overview & Revenue Model
Company Description
Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotic medicines to treat metabolic and immunological diseases in the United States. Its therapeutic programs include SYNB1618 and SY...
How the Company Makes Money
Synlogic has historically generated revenue primarily from collaboration and license arrangements (e.g., upfront payments, research funding/cost reimbursements, and potential milestone payments) rather than from product sales, because it has been ...
Synlogic Financial Statement Overview
Summary
Income Statement
18
Very Negative
Balance Sheet
56
Neutral
Cash Flow
22
Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 8.00K | 3.37M | 1.18M | 1.75M |
| Gross Profit | 0.00 | 0.00 | 8.00K | 3.37M | 1.18M | 1.75M |
| EBITDA | -3.95M | -3.53M | -22.06M | -55.31M | -63.63M | -58.12M |
| Net Income | -641.00K | -1.00M | -23.36M | -57.28M | -66.15M | -60.56M |
Balance Sheet | ||||||
| Total Assets | 14.61M | 15.45M | 19.83M | 75.55M | 110.86M | 174.74M |
| Cash, Cash Equivalents and Short-Term Investments | 14.11M | 14.67M | 18.86M | 47.75M | 77.63M | 128.59M |
| Total Debt | 0.00 | 0.00 | 0.00 | 17.27M | 20.30M | 20.59M |
| Total Liabilities | 2.06M | 3.58M | 7.08M | 32.90M | 28.25M | 27.47M |
| Stockholders Equity | 12.55M | 11.86M | 12.75M | 42.66M | 82.61M | 147.27M |
Cash Flow | ||||||
| Free Cash Flow | -3.32M | -4.36M | -31.67M | -51.83M | -57.62M | -52.88M |
| Operating Cash Flow | -3.32M | -4.36M | -31.66M | -51.61M | -56.89M | -52.20M |
| Investing Cash Flow | 155.00K | 167.00K | 25.34M | 38.77M | 58.35M | -53.25M |
| Financing Cash Flow | 0.00 | 0.00 | 172.00K | 20.94M | -2.04M | 89.38M |
Synlogic Technical Analysis
Neutral
1.22
Price Trends
0.63
Positive
0.71
Negative
1.12
Negative
Market Momentum
<0.01
Negative
55.96
Neutral
85.71
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For SYBX, the sentiment is Neutral. The current price of 1.22 is above the 20-day moving average (MA) of 0.63, above the 50-day MA of 0.63, and above the 200-day MA of 1.12, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 55.96 is Neutral, neither overbought nor oversold. The STOCH value of 85.71 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for SYBX.
Synlogic Risk Analysis
Synlogic disclosed 34 risk factors in its most recent earnings report. Synlogic reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Synlogic Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
52 Neutral | $15.99M | -10.35 | -290.37% | ― | 235.51% | 85.50% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
49 Neutral | $7.34M | 2.78 | -27.54% | ― | ― | -138.25% | |
48 Neutral | $22.75M | -1.58 | -112.05% | ― | ― | 94.17% | |
47 Neutral | $28.41M | -2.51 | -84.39% | ― | -83.00% | 19.02% | |
47 Neutral | $59.48M | -1.63 | -368.38% | ― | ― | 58.01% | |
45 Neutral | $5.77M | -0.17 | -389.34% | ― | ― | 99.36% |
* Healthcare Sector Average
SYBX
Synlogic
0.66
-0.48
-42.19%
LSTA
Lisata Therapeutics
3.12
0.62
24.80%
APVO
Aptevo Therapeutics
4.45
-132.35
-96.75%
ICU
SeaStar Medical Holding
3.89
-9.11
-70.08%
CING
Cingulate Inc
4.39
1.06
31.83%
ALLR
Allarity Therapeutics
1.49
0.41
37.96%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.