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Phathom Pharmaceuticals (PHAT)
NASDAQ:PHAT
US Market
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Phathom Pharmaceuticals (PHAT) AI Stock Analysis

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PHAT

Phathom Pharmaceuticals

(NASDAQ:PHAT)

Rating:56Neutral
Price Target:
$10.00
▼(-2.72% Downside)
Phathom Pharmaceuticals' overall stock score is driven by financial instability due to significant losses and negative cash flows. However, positive technical indicators and a favorable earnings call with strong growth and cost-saving measures provide some optimism. The stock's valuation remains challenging, but FDA exclusivity for VOQUEZNA supports long-term potential.
Positive Factors
FDA Approval
FDA's decision to approve the company's Citizen's Petition and recognize Voquezna's full 10-year exclusivity removes a big overhang on the stock.
Market Confidence
Investor sentiment following the NCE announcement demonstrated a vote of confidence, with PHAT shares closing up approximately 90%.
Revenue Growth
The company has demonstrated sequential revenue growth while utilizing strategic cost reductions.
Negative Factors
Exclusivity Concerns
Shares were severely punished—beyond what was the underlying value with only two years of exclusivity lost.
Market Valuation
PHAT's current market cap is considered to undervalue Voquezna's revenue potential.

Phathom Pharmaceuticals (PHAT) vs. SPDR S&P 500 ETF (SPY)

Phathom Pharmaceuticals Business Overview & Revenue Model

Company DescriptionPhathom Pharmaceuticals (PHAT) is a biopharmaceutical company focused on developing and commercializing innovative therapies for gastrointestinal diseases. The company primarily targets conditions such as peptic ulcer disease and gastroesophageal reflux disease (GERD) with its lead product candidate, Vonoprazan, a novel potassium-competitive acid blocker designed to provide improved efficacy and tolerability compared to traditional therapies. Phathom operates in the pharmaceuticals sector, emphasizing research, development, and potential commercialization of medications that enhance patient outcomes in digestive health.
How the Company Makes MoneyPhathom Pharmaceuticals generates revenue primarily through the commercialization of its pharmaceutical products, particularly Vonoprazan, once it receives regulatory approval and gains market access. The company may also explore partnerships with larger pharmaceutical firms for co-development and distribution agreements, which can provide upfront payments, milestone payments, and royalties on sales. Additionally, the company's revenue stream could be bolstered by securing licensing agreements and collaborations that leverage its research capabilities and product pipeline, allowing it to monetize its intellectual property and scientific advancements.

Phathom Pharmaceuticals Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: 18.43%|
Next Earnings Date:Nov 06, 2025
Earnings Call Sentiment Positive
The earnings call reflects a positive sentiment overall, with strong growth in prescriptions and revenue, a solid financial position, and effective cost-saving measures. However, there are some challenges, including potential supply disruptions and strategic shifts in sales focus.
Q2-2025 Updates
Positive Updates
Significant Growth in VOQUEZNA Prescriptions
Over 580,000 VOQUEZNA prescriptions have been filled, with a 49% growth in 14 weeks. In Q2, 173,000 prescriptions were filled, showing a 36% growth over Q1.
Positive Financial Performance
Reported $39.5 million in revenue for Q2, representing a 39% growth over Q1 revenue. The company also achieved a $12 million reduction in non-GAAP OpEx compared to Q1.
Improved Cash Position and Guidance
Ended the quarter with approximately $150 million in cash. Provided revenue guidance of $165 million to $175 million for full year 2025, above analyst consensus.
Exclusivity Achieved for VOQUEZNA
The FDA updated the Orange Book to reflect exclusivity for VOQUEZNA tablets through May 2032, potentially extending exclusivity into 2033.
Cost-Saving Initiatives
Implemented cost-saving initiatives, reducing Q2 non-GAAP operating expenses by $12 million compared to Q1, with further reductions projected.
Negative Updates
Potential Supply Disruption
There could be a supply disruption in the VOQUEZNA triple pack due to issues with clarithromycin tablets, but no disruption has occurred yet.
Focus Shift and Sales Target Changes
Phathom is shifting focus from primary care physicians to gastroenterologists, dropping over 20,000 PCP targets, which may impact new writer conversions.
Company Guidance
During the Phathom Pharmaceuticals second quarter 2025 earnings call, key metrics highlighted included a 49% growth in VOQUEZNA prescriptions over 14 weeks, reaching over 580,000 prescriptions filled by July 25. In Q2 alone, 173,000 prescriptions were filled, marking a 36% increase from Q1. Commercial access for VOQUEZNA remains strong, with over 80% of lives covered, and 68% of Q2 prescriptions were filled through the retail channel. The company reported $39.5 million in revenue for Q2, a 39% increase over Q1, and ended the quarter with approximately $150 million in cash. Phathom provided a full-year 2025 revenue guidance of $165 million to $175 million and communicated cost-saving measures leading to a reduction in Q2 non-GAAP operating expenses by $12 million compared to Q1. The company is on track to achieve profitability by 2026, supported by ongoing revenue growth and disciplined cost management.

Phathom Pharmaceuticals Financial Statement Overview

Summary
Phathom Pharmaceuticals exhibits significant revenue growth but faces substantial net losses and negative cash flows. The negative equity and high financial leverage underscore financial instability, despite maintaining financing cash flows.
Income Statement
42
Neutral
Phathom Pharmaceuticals has shown significant revenue growth, with TTM (Trailing-Twelve-Months) revenue increasing to $81.86 million from $55.25 million annually. However, the company is experiencing substantial losses, with a negative net profit margin and EBIT margin in both TTM and annual reports. The gross profit margin is strong at approximately 86.2% in TTM, but the net loss remains a concern, impacting the overall profitability.
Balance Sheet
35
Negative
The balance sheet indicates a negative stockholders' equity of $338.38 million, reflecting high liabilities compared to assets. Total debt has reduced, but the company still faces a high debt-to-equity ratio due to negative equity. This presents a risk of instability. The equity ratio is also negative, further emphasizing the financial leverage and instability concerns.
Cash Flow
40
Negative
Operating cash flow remains negative, with a worsening trend in TTM at -$282.68 million. Free cash flow also decreased, indicating potential cash flow challenges. However, the company has managed to maintain financing cash flows, which slightly offsets the negative operating cash flow impact. The operating cash flow to net income ratio reflects inefficiency in converting income to cash flow.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue55.25M682.00K0.000.000.00
Gross Profit47.28M515.00K-620.00K-521.00K-300.00K
EBITDA-261.52M-159.05M-171.82M-134.56M-124.19M
Net Income-334.33M-201.59M-223.01M-148.09M-133.32M
Balance Sheet
Total Assets378.32M413.84M164.81M189.43M295.11M
Cash, Cash Equivalents and Short-Term Investments297.26M381.39M155.38M183.26M287.50M
Total Debt201.91M139.03M97.07M91.34M49.02M
Total Liabilities631.90M486.60M239.62M117.28M100.84M
Stockholders Equity-253.58M-72.76M-74.81M72.16M194.27M
Cash Flow
Free Cash Flow-266.90M-139.21M-147.57M-148.94M-70.73M
Operating Cash Flow-266.77M-137.58M-146.53M-148.62M-69.69M
Investing Cash Flow-135.00K-1.63M-1.04M-328.00K-1.04M
Financing Cash Flow182.77M367.58M120.04M44.71M114.46M

Phathom Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.28
Price Trends
50DMA
8.84
Positive
100DMA
6.61
Positive
200DMA
7.53
Positive
Market Momentum
MACD
0.35
Negative
RSI
66.42
Neutral
STOCH
87.13
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PHAT, the sentiment is Positive. The current price of 10.28 is above the 20-day moving average (MA) of 8.81, above the 50-day MA of 8.84, and above the 200-day MA of 7.53, indicating a bullish trend. The MACD of 0.35 indicates Negative momentum. The RSI at 66.42 is Neutral, neither overbought nor oversold. The STOCH value of 87.13 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PHAT.

Phathom Pharmaceuticals Risk Analysis

Phathom Pharmaceuticals disclosed 82 risk factors in its most recent earnings report. Phathom Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Phathom Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (60)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$600.18M6.18376.09%105.62%
60
Neutral
$190.95M7.36-18.12%-66.80%-157.68%
60
Neutral
HK$18.14B4.94-4.00%3.36%10.19%-23.62%
56
Neutral
$729.30M181.41%1049.81%7.85%
56
Neutral
$697.29M-87.42%-100.08%-2.45%
47
Neutral
$312.38M-48.57%-100.00%83.98%
43
Neutral
$225.29M-59.60%-100.00%31.43%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PHAT
Phathom Pharmaceuticals
10.38
-1.79
-14.71%
RIGL
Rigel
34.52
21.85
172.45%
BNTC
Benitec Biopharma
12.39
3.17
34.38%
ALLO
Allogene Therapeutics
1.03
-1.32
-56.17%
TRDA
Entrada Therapeutics Inc
5.16
-10.65
-67.36%
AMLX
Amylyx Pharmaceuticals Inc
8.20
6.21
312.06%

Phathom Pharmaceuticals Corporate Events

Product-Related AnnouncementsRegulatory Filings and Compliance
Phathom Pharmaceuticals Gains FDA Exclusivity for VOQUEZNA
Positive
Jun 16, 2025

On June 16, 2025, Phathom Pharmaceuticals announced that the FDA updated the Orange Book to reflect a full 10-year period of non-patent New Chemical Entity exclusivity for VOQUEZNA tablets. This correction confirms VOQUEZNA’s exclusivity through May 3, 2032, supporting its long-term commercial potential and aligning with statutory requirements.

The most recent analyst rating on (PHAT) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on Phathom Pharmaceuticals stock, see the PHAT Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Phathom Pharmaceuticals Holds Annual Stockholders Meeting
Neutral
Jun 9, 2025

On June 3, 2025, Phathom Pharmaceuticals held its Annual Meeting of Stockholders, where key decisions were made regarding the election of directors, ratification of the accounting firm, and executive compensation. The stockholders elected Class III directors, ratified Ernst & Young LLP as the accounting firm for 2025, approved executive compensation, and decided to hold annual votes on executive compensation, aligning with the board’s recommendations.

The most recent analyst rating on (PHAT) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on Phathom Pharmaceuticals stock, see the PHAT Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and StrategyRegulatory Filings and Compliance
Phathom Pharmaceuticals Gains FDA Approval for VOQUEZNA® Exclusivity
Positive
Jun 6, 2025

On June 6, 2025, Phathom Pharmaceuticals announced that the FDA approved their Citizen Petition, filed in December 2024, to correct the Orange Book and recognize a 10-year New Chemical Entity exclusivity for VOQUEZNA® (vonoprazan) tablets, extending through May 3, 2032. This approval enhances Phathom’s market position by securing extended exclusivity for their product, potentially impacting their commercialization strategy and competitive landscape in the gastrointestinal treatment market.

The most recent analyst rating on (PHAT) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on Phathom Pharmaceuticals stock, see the PHAT Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 12, 2025