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Phathom Pharmaceuticals (PHAT)
NASDAQ:PHAT
US Market

Phathom Pharmaceuticals (PHAT) AI Stock Analysis

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Phathom Pharmaceuticals

(NASDAQ:PHAT)

Rating:54Neutral
Price Target:
$10.00
▼(-6.02%Downside)
Phathom Pharmaceuticals faces significant financial challenges, with high net losses and negative cash flows weighing heavily on its score. Technical analysis shows positive momentum, but valuation concerns persist due to negative profitability metrics. Recent corporate events, including FDA approval for exclusivity, offer some positive outlook, but overall instability remains a concern.
Positive Factors
Innovation
VOQUEZNA acts as a novel and differentiated potassium competitive acid blocker (PCAB) for GERD and NERD patients, representing the first innovation in GERD in decades.
Market Confidence
Investor sentiment following the NCE announcement demonstrated a vote of confidence, with PHAT shares closing up approximately 90%.
Regulatory Approval
FDA's decision to approve the company's Citizen's Petition and recognize Voquezna's full 10-year exclusivity removes a big overhang on the stock.
Negative Factors
C-Suite Changes
A number of C-suite changes were announced, including the departure of the COO, CCO, and CFO, effective within a few weeks.
Target Price Reduction
Strategic updates have led to a reduction in the price target from $28 to $20 per share.

Phathom Pharmaceuticals (PHAT) vs. SPDR S&P 500 ETF (SPY)

Phathom Pharmaceuticals Business Overview & Revenue Model

Company DescriptionPhathom Pharmaceuticals (PHAT) is a biopharmaceutical company focused on the development and commercialization of novel treatments for gastrointestinal (GI) diseases. The company operates primarily in the pharmaceutical sector with a commitment to addressing unmet medical needs in the GI space. Phathom's core product portfolio includes innovative therapies designed to improve the lives of patients suffering from acid-related disorders and other GI conditions.
How the Company Makes MoneyPhathom Pharmaceuticals generates revenue through the development, approval, and commercialization of its pharmaceutical products. The company's primary revenue stream is expected to come from the sales of its lead product candidates once they receive regulatory approval and enter the market. Phathom is involved in strategic partnerships and licensing agreements, which can provide upfront payments, milestone payments, and royalties, contributing to its earnings. These partnerships are crucial for funding research and development activities and for gaining access to additional resources and expertise necessary for successful product commercialization.

Phathom Pharmaceuticals Earnings Call Summary

Earnings Call Date:May 01, 2025
(Q1-2025)
|
% Change Since: 148.02%|
Next Earnings Date:Aug 07, 2025
Earnings Call Sentiment Neutral
Phathom Pharmaceuticals is experiencing solid prescription growth and is making strides towards profitability through cost management. However, challenges such as stock price constraints, leadership transitions, and strategic promotional cutbacks underscore the need for careful navigation in the coming quarters.
Q1-2025 Updates
Positive Updates
VOQUEZNA Revenue Milestone
Phathom Pharmaceuticals achieved an annualized run-rate of $120 million in net revenues for VOQUEZNA within the first 18 months of launch.
Prescription Growth
VOQUEZNA prescriptions exceeded 390,000 from launch through April 18, showing a 30% growth over the last 8 weeks and an 8% increase in the first quarter over the fourth quarter.
Commercial Coverage
VOQUEZNA has over 120 million lives covered, representing more than 80% of the total commercially insured market in the U.S.
Cost Management Initiatives
Phathom plans to reduce operating expenses to less than $55 million per quarter by Q4 2025, aiming for profitability in 2026 without additional financing.
Negative Updates
Stock Price and Capital Access
Phathom's stock trading near $4 per share limits flexible access to capital, leading to a need for stringent cost management to avoid dilutive financing.
Personnel Changes and Reduction in Force
Significant leadership changes with transitions of key executives and a 6% reduction in total staffing as part of cost-saving measures.
Potential Supply Disruption
Phathom is monitoring a potential future disruption in the supply of VOQUEZNA TRIPLE PAKs, although no commercial disruption has occurred yet.
Direct-to-Consumer (DTC) Promotion Cutbacks
Phathom is halting broadcast cable and streaming television promotions due to lower ROI, focusing instead on digital promotions.
Paused Eosinophilic Esophagitis Study
Plans for a Phase 2 eosinophilic esophagitis study have been paused, pending the outcome of the Citizens Petition decision and strategic considerations.
Company Guidance
During the Phathom Pharmaceuticals First Quarter 2025 earnings call, CEO Steve Basta provided guidance emphasizing the company's focus on growing VOQUEZNA's sales and achieving profitability by 2026. The company has set a target to reduce its operating expenses to less than $55 million per quarter by Q4 2025, excluding interest, stock compensation, and certain accruals. This cost management strategy is intended to enable Phathom to reach profitable operations without requiring additional financing. The call also highlighted a successful start for VOQUEZNA, with an annualized run-rate of $120 million in net revenues within the first 18 months of launch. Phathom reported net revenues of $28.5 million for Q1 2025 and ended the quarter with $212 million in cash. The company plans to maintain its sales force strength while implementing cost-saving measures, such as reducing direct-to-consumer broadcast spending and pausing certain R&D activities. The company remains focused on managing costs and driving revenue growth to build a sustainable business.

Phathom Pharmaceuticals Financial Statement Overview

Summary
Phathom Pharmaceuticals exhibits significant revenue growth, but substantial net losses, negative cash flows, and negative equity highlight financial instability. Reliance on external financing further increases risk.
Income Statement
42
Neutral
Phathom Pharmaceuticals has shown significant revenue growth, with TTM (Trailing-Twelve-Months) revenue increasing to $81.86 million from $55.25 million annually. However, the company is experiencing substantial losses, with a negative net profit margin and EBIT margin in both TTM and annual reports. The gross profit margin is strong at approximately 86.2% in TTM, but the net loss remains a concern, impacting the overall profitability.
Balance Sheet
35
Negative
The balance sheet indicates a negative stockholders' equity of $338.38 million, reflecting high liabilities compared to assets. Total debt has reduced, but the company still faces a high debt-to-equity ratio due to negative equity. This presents a risk of instability. The equity ratio is also negative, further emphasizing the financial leverage and instability concerns.
Cash Flow
40
Negative
Operating cash flow remains negative, with a worsening trend in TTM at -$282.68 million. Free cash flow also decreased, indicating potential cash flow challenges. However, the company has managed to maintain financing cash flows, which slightly offsets the negative operating cash flow impact. The operating cash flow to net income ratio reflects inefficiency in converting income to cash flow.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
81.86M55.25M682.00K0.000.000.00
Gross Profit
70.59M47.28M515.00K-620.00K-521.00K-300.00K
EBIT
-286.38M-277.47M-167.31M-172.44M-135.08M-125.67M
EBITDA
-274.92M-261.52M-159.05M-171.82M-134.56M-124.19M
Net Income Common Stockholders
-251.47M-334.33M-201.59M-223.01M-148.09M-133.32M
Balance SheetCash, Cash Equivalents and Short-Term Investments
212.31M297.26M381.39M155.38M183.26M287.50M
Total Assets
294.21M378.32M413.84M164.81M189.43M295.11M
Total Debt
203.56M201.91M139.03M97.07M91.34M49.02M
Net Debt
-8.75M-95.35M-242.36M-58.31M-91.92M-238.48M
Total Liabilities
632.58M631.90M486.60M239.62M117.28M100.84M
Stockholders Equity
-338.38M-253.58M-72.76M-74.81M72.16M194.27M
Cash FlowFree Cash Flow
-282.66M-266.90M-139.21M-147.57M-148.94M-70.73M
Operating Cash Flow
-282.68M-266.77M-137.58M-146.53M-148.62M-69.69M
Investing Cash Flow
-113.00K-135.00K-1.63M-1.04M-328.00K-1.04M
Financing Cash Flow
172.87M182.77M367.58M120.04M44.71M114.46M

Phathom Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price10.64
Price Trends
50DMA
4.65
Positive
100DMA
5.22
Positive
200DMA
9.13
Positive
Market Momentum
MACD
1.54
Negative
RSI
86.40
Negative
STOCH
70.20
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PHAT, the sentiment is Positive. The current price of 10.64 is above the 20-day moving average (MA) of 5.86, above the 50-day MA of 4.65, and above the 200-day MA of 9.13, indicating a bullish trend. The MACD of 1.54 indicates Negative momentum. The RSI at 86.40 is Negative, neither overbought nor oversold. The STOCH value of 70.20 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PHAT.

Phathom Pharmaceuticals Risk Analysis

Phathom Pharmaceuticals disclosed 82 risk factors in its most recent earnings report. Phathom Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Phathom Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
77
Outperform
$366.74M9.90531.78%68.74%
61
Neutral
$288.07M9.397.22%5.74%24.45%
57
Neutral
$492.06M-83.24%-100.32%-197.69%
54
Neutral
$742.82M181.41%3055.71%-18.80%
54
Neutral
$432.61M-48.57%-100.00%83.98%
54
Neutral
$5.37B3.26-45.10%3.30%16.81%0.02%
43
Neutral
$293.10M-59.60%-100.00%31.43%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PHAT
Phathom Pharmaceuticals
10.64
-1.06
-9.06%
RIGL
Rigel
20.52
11.26
121.60%
BNTC
Benitec Biopharma
16.48
8.99
120.03%
ALLO
Allogene Therapeutics
1.34
-0.96
-41.74%
TRDA
Entrada Therapeutics Inc
7.59
-7.62
-50.10%
AMLX
Amylyx Pharmaceuticals Inc
5.52
3.87
234.55%

Phathom Pharmaceuticals Corporate Events

Executive/Board ChangesShareholder Meetings
Phathom Pharmaceuticals Holds Annual Stockholders Meeting
Neutral
Jun 9, 2025

On June 3, 2025, Phathom Pharmaceuticals held its Annual Meeting of Stockholders, where key decisions were made regarding the election of directors, ratification of the accounting firm, and executive compensation. The stockholders elected Class III directors, ratified Ernst & Young LLP as the accounting firm for 2025, approved executive compensation, and decided to hold annual votes on executive compensation, aligning with the board’s recommendations.

The most recent analyst rating on (PHAT) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on Phathom Pharmaceuticals stock, see the PHAT Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and StrategyRegulatory Filings and Compliance
Phathom Pharmaceuticals Gains FDA Approval for VOQUEZNA® Exclusivity
Positive
Jun 6, 2025

On June 6, 2025, Phathom Pharmaceuticals announced that the FDA approved their Citizen Petition, filed in December 2024, to correct the Orange Book and recognize a 10-year New Chemical Entity exclusivity for VOQUEZNA® (vonoprazan) tablets, extending through May 3, 2032. This approval enhances Phathom’s market position by securing extended exclusivity for their product, potentially impacting their commercialization strategy and competitive landscape in the gastrointestinal treatment market.

The most recent analyst rating on (PHAT) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on Phathom Pharmaceuticals stock, see the PHAT Stock Forecast page.

Executive/Board Changes
Phathom Pharmaceuticals Appoints Theodore Schroeder to Board
Positive
Apr 16, 2025

Phathom Pharmaceuticals has appointed Theodore R. Schroeder to its Board of Directors as a Class I director, effective April 16, 2025. Mr. Schroeder, with over 30 years of experience in drug development and commercialization, will serve on the audit committee and brings significant leadership experience from his previous roles at various pharmaceutical companies. His appointment is expected to strengthen the board with his extensive industry knowledge and leadership skills.

Executive/Board ChangesBusiness Operations and Strategy
Phathom Pharmaceuticals Announces Leadership Transition in 2025
Neutral
Apr 1, 2025

Phathom Pharmaceuticals announced a leadership transition effective April 1, 2025, with Steven Basta appointed as the new Chief Executive Officer, President, and Class I director, succeeding Terrie Curran who resigned for personal reasons. The company also adopted a 2025 Employment Inducement Incentive Award Plan to attract new talent, reserving 2,500,000 shares for equity awards. This strategic move aims to strengthen the company’s leadership and incentivize new hires, potentially impacting its market position and stakeholder interests.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.